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公开(公告)号：US20230392146A1
公开(公告)日：2023-12-07
申请号：US18120030
申请日：2023-03-10
Applicant: UNIVERSITY OF MASSACHUSETTS
Inventor： Anastasia Khvorova , Chantal Ferguson , Sarah Davis
IPC: C12N15/113 , A61P25/28 , C12N15/86
CPC classification number: C12N15/113 , A61P25/28 , C12N15/86 , C12N2310/11 , C12N2310/315 , C12N2310/32 , C12N2750/14143
Abstract: This disclosure relates to novel APP targeting sequences. Novel APP targeting oligonucleotides for the treatment of neurodegenerative diseases are also provided.
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2.发明公开公开(公告)号：US20240067967A1
公开(公告)日：2024-02-29
申请号：US18321971
申请日：2023-05-23
Inventor： Anastasia Khvorova , Vignesh Narayan Hariharan , Sarah Davis , Annabelle Biscans , Ananth Karumanchi
IPC: C12N15/113 , A61P9/12
CPC classification number: C12N15/113 , A61P9/12 , C12N2310/11 , C12N2310/312 , C12N2310/315 , C12N2310/321
Abstract: This disclosure relates to novel targets for angiogenic disorders. Novel oligonucleotides are also provided. Methods of using the novel oligonucleotides for the treatment of angiogenic disorders (e.g., preeclampsia) are also provided.
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公开(公告)号：US11702659B2
公开(公告)日：2023-07-18
申请号：US17846526
申请日：2022-06-22
Inventor： Anastasia Khvorova , Vignesh Narayan Hariharan , Sarah Davis , Annabelle Biscans , Ananth Karumanchi
IPC: C07H21/04 , C12N15/113 , A61P7/00
CPC classification number: C12N15/113 , A61P7/00 , C12N2310/11 , C12N2310/315 , C12N2310/321 , C12N2310/322 , C12N2310/344 , C12N2310/346 , C12N2320/32
Abstract: This disclosure relates to novel targets for angiogenic disorders. Novel oligonucleotides are also provided. Methods of using the novel oligonucleotides for the treatment of angiogenic disorders (e.g., preeclampsia) are also provided.
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公开(公告)号：US20230021431A1
公开(公告)日：2023-01-26
申请号：US17333839
申请日：2021-05-28
Applicant: UNIVERSITY OF MASSACHUSETTS
Inventor： Anastasia Khvorova , Jonathan Watts , Zachary Kennedy , Annabelle Biscans , Bruno Miguel da Cruz Godinho , Chantal Ferguson , Dimas Echeverria Moreno , Ken Yamada , Daniel O'Reilly , Kathryn Monopoli , Vignesh Narayan Hariharan , Qi Tang , Sarah Davis , Samuel Hildebrand , Socheata Ly , Minwook Shin , Pranathi Meda Krishnamurthy , Nicholas McHugh , Jacquelyn Sousa , Jillian Caiazzi , Yann Thillier , Gitali Devi
IPC: C12N15/113
Abstract: This disclosure relates to novel SARS-CoV-2 targeting sequences. Novel SARS-CoV-2 targeting oligonucleotides for the treatment of SARS-CoV-2 infection are also provided.
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公开(公告)号：US20210115442A1
公开(公告)日：2021-04-22
申请号：US16999759
申请日：2020-08-21
Applicant: UNIVERSITY OF MASSACHUSETTS
Inventor： Anastasia Khvorova , Julia Alterman , Sarah Davis , Anton Turanov
IPC: C12N15/113
Abstract: Novel oligonucleotides that are fully chemically stabilized are provided. Methods of using oligonucleotides that are fully chemically stabilized are also provided.
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Patent Agency Ranking
公开(公告)号：US20250043284A1
公开(公告)日：2025-02-06
申请号：US18760779
申请日：2024-07-01
Applicant: UNIVERSITY OF MASSACHUSETTS
Inventor： Anastasia Khvorova , Chantal Ferguson , Sarah Davis , Kathryn Monopoli
IPC: C12N15/113 , A61K47/54 , A61K47/55 , A61K48/00
Abstract: This disclosure relates to novel SNCA targeting sequences. Novel SNCA targeting oligonucleotides for the treatment of neurodegenerative diseases are also provided.
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公开(公告)号：US11279930B2
公开(公告)日：2022-03-22
申请号：US16550076
申请日：2019-08-23
Applicant: UNIVERSITY OF MASSACHUSETTS
Inventor： Anastasia Khvorova , Julia Alterman , Sarah Davis , Anton Turanov
IPC: C12N15/113
Abstract: Novel oligonucleotides that are fully chemically stabilized are provided. Methods of using oligonucleotides that are fully chemically stabilized are also provided.
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公开(公告)号：US20210363524A1
公开(公告)日：2021-11-25
申请号：US17204483
申请日：2021-03-17
Applicant: UNIVERSITY OF MASSACHUSETTS
Inventor： Anastasia Khvorova , Chantal Ferguson , Sarah Davis , Kathryn Monopoli
IPC: C12N15/113 , A61K47/54 , A61K48/00 , A61K47/55
Abstract: This disclosure relates to novel SNCA targeting sequences. Novel SNCA targeting oligonucleotides for the treatment of neurodegenerative diseases are also provided.
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公开(公告)号：US12297430B2
公开(公告)日：2025-05-13
申请号：US17580269
申请日：2022-01-20
Applicant: UNIVERSITY OF MASSACHUSETTS
Inventor： Anastasia Khvorova , Julia Alterman , Sarah Davis , Anton Turanov
IPC: C12N15/113
Abstract: Novel oligonucleotides that are fully chemically stabilized are provided. Methods of using oligonucleotides that are fully chemically stabilized are also provided.
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公开(公告)号：US20240425860A1
公开(公告)日：2024-12-26
申请号：US18675670
申请日：2024-05-28
Applicant: UNIVERSITY OF MASSACHUSETTS
Inventor： Anastasia Khvorova , Jonathan Watts , Zachary Kennedy , Annabelle Biscans , Bruno Miguel da Cruz Godinho , Chantal Ferguson , Dimas Echeverria Moreno , Ken Yamada , Daniel O'Reilly , Kathryn Monopoli , Vignesh Narayan Hariharan , Qi Tang , Sarah Davis , Samuel Hildebrand , Socheata Ly , Minwook Shin , Pranathi Meda Krishnamurthy , Nicholas McHugh , Jacquelyn Sousa , Jillian Caiazzi , Yann Thillier , Gitali Devi
IPC: C12N15/113
Abstract: This disclosure relates to novel SARS-CoV-2 targeting sequences. Novel SARS-CoV-2 targeting oligonucleotides for the treatment of SARS-CoV-2 infection are also provided.
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