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公开(公告)号:US20180251827A1
公开(公告)日:2018-09-06
申请号:US15962944
申请日:2018-04-25
Inventor: Daniel T. CHIU , Bryant S. FUJIMOTO , Alexander R. GANSEN , Gloria S. YEN , Robert M. LORENZ
IPC: C12Q1/6851
CPC classification number: C12Q1/6851 , C12Q1/6806 , C12Q2527/146 , C12Q2531/113 , C12Q2545/114
Abstract: Methods, devices and systems for performing digital measurements are provided.
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公开(公告)号:US20200157615A1
公开(公告)日:2020-05-21
申请号:US16783037
申请日:2020-02-05
Inventor: Daniel T. CHIU , Bryant S. FUJIMOTO , Alexander R. GANSEN , Gloria S. YEN , Robert M. LORENZ
IPC: C12Q1/6851 , C12Q1/6806
Abstract: Methods and systems for digital measurements are provided. In an embodiment, the method includes producing a plurality of droplets, wherein at least one of the droplets of the plurality of droplets contains an analyte molecule from a sample; measuring at least a first portion of the plurality of droplets to determine individual volumes of droplets in the first portion of the plurality of droplets; analyzing at least a second portion of the plurality of droplets to determine a number of droplets in the second portion of the plurality of droplets that contain the analyte molecule; and using individual volumes of the droplets in the first portion of the plurality of droplets and the number of droplets in the second portion of the plurality of droplets that contain the analyte molecule to determine the concentration of the analyte molecule in the sample.
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公开(公告)号:US20170175174A1
公开(公告)日:2017-06-22
申请号:US15301798
申请日:2015-04-08
Inventor: Daniel T. CHIU , Jason E. KREUTZ , Gloria S. YEN , Bryant S. FUJIMOTO
CPC classification number: C12Q1/6816 , G01N15/1434 , G01N21/47 , G01N21/6428 , G01N2015/1445 , G01N2021/6439 , G06K9/0014 , G06K9/4647 , G06T7/62 , G06T2207/10056 , G06T2207/30072 , C12Q2531/113 , C12Q2537/157 , C12Q2563/107 , C12Q2563/159
Abstract: Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure.
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公开(公告)号:US20240263214A1
公开(公告)日:2024-08-08
申请号:US18581760
申请日:2024-02-20
Inventor: Daniel T. CHIU , Jason E. KREUTZ , Gloria S. YEN , Bryant S. FUJIMOTO
IPC: C12Q1/6816 , G01N15/1434 , G01N21/47 , G01N21/64 , G06T7/62 , G06V20/69
CPC classification number: C12Q1/6816 , G01N15/1434 , G01N21/47 , G01N21/6428 , G06T7/62 , G06V20/695 , G01N2015/1445 , G01N2021/6439 , G06T2207/10056 , G06T2207/30072
Abstract: Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure.
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公开(公告)号:US20220356512A1
公开(公告)日:2022-11-10
申请号:US17813415
申请日:2022-07-19
Inventor: Daniel T. CHIU , Jason E. KREUTZ , Gloria S. YEN , Bryant S. FUJIMOTO
Abstract: Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure.
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