公开(公告)号：US4266021A

公开(公告)日：1981-05-05

申请号：US968202

申请日：1978-12-11

申请人： Ulf T. G. Nylen ,  Lars-Goran Olsson ,  Bengt G. Paulsson ,  Lars A. G. Qvarnstrom ,  Rolf H. L. Wichers

发明人： Ulf T. G. Nylen ,  Lars-Goran Olsson ,  Bengt G. Paulsson ,  Lars A. G. Qvarnstrom ,  Rolf H. L. Wichers

IPC分类号： G01N33/48 ,  A61B5/00 ,  A61M1/16 ,  A61M1/34 ,  C12Q1/00 ,  G01N33/487 ,  C12M1/34 ,  C12Q1/54 ,  G01N31/14

CPC分类号： C12Q1/00 ,  A61B5/14525 ,  A61B5/14865 ,  A61M1/16 ,  A61M1/1609 ,  A61M1/3437 ,  Y10T436/255

摘要： A method and apparatus is provided for measuring the content of a compound in a liquid medium, and which is particularly useful for measuring the concentration of a low molecular weight compound in a complex medium in which there is provided a dialyzer in contact with the complex fluid medium and through which dialysis fluid is conducted to receive by diffusion a portion of the low molecular weight compound to produce a dialysate. The dialysate with the low molecular weight commpound to be examined is first conducted through a venting device for removal of gaseous particles therefrom before conduction through a reaction chamber containing enzymes for promoting the conversion of the low molecular weight compound in the dialysate into a converted reaction product. The dialysate is then conducted from the reaction chamber to a measuring unit for measuring the concentration of the converted reaction product in the dialysate conducted from the reaction chamber, the concentration of the converted reaction product being representative of the content of the low molecular weight compound in the complex fluid medium.

摘要翻译： 提供了一种用于测量液体介质中化合物含量的方法和装置，其特别可用于测量复合介质中的低分子量化合物的浓度，其中提供了与复合流体接触的透析器 通过透析液进行渗透以通过扩散一部分低分子量化合物以产生透析液。 首先通过排气装置进行待检查的低分子量通气的透析液，以便在通过含有促进透析液中低分子量化合物转化为转化反应产物的酶的反应室之前从其中除去气态颗粒 。 然后将透析液从反应室传导到测量单元，用于测量从反应室进行的透析液中转化的反应产物的浓度，转化反应产物的浓度代表低分子量化合物的含量 复合流体介质。