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公开(公告)号：US20090203581A1
公开(公告)日：2009-08-13
申请号：US11995351
申请日：2006-07-07
申请人： Ulrich Sensfuss , Leif Christensen , Jane Spetzler , Kilian Waldemar Conde Frieboes , Henning Thogersen
发明人： Ulrich Sensfuss , Leif Christensen , Jane Spetzler , Kilian Waldemar Conde Frieboes , Henning Thogersen
CPC分类号： C07K14/685 , A61K47/542 , A61K47/545
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US20080306008A1
公开(公告)日：2008-12-11
申请号：US11666800
申请日：2005-11-04
申请人： Ulrich Sensfuss , Leif Christensen
发明人： Ulrich Sensfuss , Leif Christensen
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US07541430B2
公开(公告)日：2009-06-02
申请号：US11268268
申请日：2005-11-07
申请人： Ulrich Sensfuss , Kilian Waldemar Conde Frieboes , Leif Christensen , Ingrid Vivika Petterson , Thomas Kruse Hansen , Michael Ankersen , Kjeld Madsen
发明人： Ulrich Sensfuss , Kilian Waldemar Conde Frieboes , Leif Christensen , Ingrid Vivika Petterson , Thomas Kruse Hansen , Michael Ankersen , Kjeld Madsen
IPC分类号： A61K38/10
摘要： Novel cyclic and linear peptides of the formula R1—X—X1—X2—X3—X4—X5—X6—X7—X8—X9—X10—X11—R2 are useful in the treatment of obesity are provided.
摘要翻译： 式R1-X-X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-R2的新型环状和线性肽可用于治疗肥胖症。
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公开(公告)号：US20080280820A1
公开(公告)日：2008-11-13
申请号：US11666795
申请日：2005-11-04
申请人： Ulrich Sensfuss , Leif Christensen
发明人： Ulrich Sensfuss , Leif Christensen
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
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公开(公告)号：US20070027091A1
公开(公告)日：2007-02-01
申请号：US11278014
申请日：2006-03-30
申请人： Kilian Conde-Frieboes , Ulrich Sensfuss , Kjeld Madsen , Nils Johansen , Leif Christensen , Thomas Hansen , Birgitte Wulff
发明人： Kilian Conde-Frieboes , Ulrich Sensfuss , Kjeld Madsen , Nils Johansen , Leif Christensen , Thomas Hansen , Birgitte Wulff
摘要： Small cyclic peptides of the formula X1-X2-X3-X4-X5-X6-X7-R1 comprising 7-12 amino acid residues are provided. Said peptides are MC4 receptor agonists, and thus useful in the treatment of obesity and related diseases.
摘要翻译： 提供了包含7-12个氨基酸残基的式X1-X2-X3-X4-X5-X6-X7-R-1的小环肽。 所述肽是MC4受体激动剂，因此可用于治疗肥胖症和相关疾病。
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公开(公告)号：US20070244054A1
公开(公告)日：2007-10-18
申请号：US11268268
申请日：2005-11-07
申请人： Ulrich Sensfuss , Kilian Conde Frieboes , Leif Christensen , Ingrid Petterson , Thomas Hansen , Michael Ankersen , Kjeld Madsen
发明人： Ulrich Sensfuss , Kilian Conde Frieboes , Leif Christensen , Ingrid Petterson , Thomas Hansen , Michael Ankersen , Kjeld Madsen
摘要： Novel cyclic and linear peptides of the formula R1—X—X1—X2—X3—X4—X5—X6—X7—X8—X9—X10—X11—R2 are useful in the treatment of obesity are provided.
摘要翻译： 新型的具有式R 1至X 2的环状和线性肽-X -X 2 -X 3 -X 3 - 第4〜第5至第六至第六至第七至第十七至第十七 另外还提供了用于治疗肥胖症的SUP＃9 - 10 - 10 - 11 - 2 - 2。
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公开(公告)号：US07517854B2
公开(公告)日：2009-04-14
申请号：US11278014
申请日：2006-03-30
申请人： Kilian Waldemar Conde-Frieboes , Ulrich Sensfuss , Kjeld Madsen , Nils Langeland Johansen , Leif Christensen , Thomas Kruse Hansen , Birgitte Schjellerup Wulff
发明人： Kilian Waldemar Conde-Frieboes , Ulrich Sensfuss , Kjeld Madsen , Nils Langeland Johansen , Leif Christensen , Thomas Kruse Hansen , Birgitte Schjellerup Wulff
IPC分类号： A61K38/12
摘要： Small cyclic peptides of the formula X1-X2-X3-X4-X5-X6-X7-R1 comprising 7-12 amino acid residues are provided. Said peptides are MC4 receptor agonists, and thus useful in the treatment of obesity and related diseases.
摘要翻译： 提供了包含7-12个氨基酸残基的式X1-X2-X3-X4-X5-X6-X7-R1的小环肽。 所述肽是MC4受体激动剂，因此可用于治疗肥胖症和相关疾病。
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公开(公告)号：US20090088388A1
公开(公告)日：2009-04-02
申请号：US12168993
申请日：2008-07-08
申请人： Ulrich Sensfuss , Kilian Waldemar Conde Frieboes , Leif Christensen , Ingrid Vivika Petterson , Thomas Kruse Hansen , Michael Ankersen , Kjeld Madsen
发明人： Ulrich Sensfuss , Kilian Waldemar Conde Frieboes , Leif Christensen , Ingrid Vivika Petterson , Thomas Kruse Hansen , Michael Ankersen , Kjeld Madsen
摘要： Novel cyclic and linear peptides of the formula R1—X—X1—X2—X3—X4—X5—X6—X7—X8—X9—X10—X11—R2 are useful in the treatment of obesity are provided.
摘要翻译： 式R1-X-X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-R2的新型环状和线性肽可用于治疗肥胖症。
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9.发明授权公开(公告)号：US08354189B2
公开(公告)日：2013-01-15
申请号：US12525680
申请日：2008-01-24
申请人： Phat T. Pham , Dinh B. Le , Mark N. Obrovac , Leif Christensen
发明人： Phat T. Pham , Dinh B. Le , Mark N. Obrovac , Leif Christensen
IPC分类号： H01M4/34
CPC分类号： H01M4/621 , H01M4/134 , H01M4/1395 , H01M4/38 , H01M4/386 , H01M4/387 , H01M4/525 , H01M10/0525 , Y10T29/49115
摘要： Provided are electrode compositions for lithium-ion electrochemical cells that include novel binders. The novel binders include lithium polysalts of carboxylic and sulfonic acids, lithium salts of copolymers of acids, lithium polysulfonate fluoropolymers, a cured phenolic resin, cured glucose, and combinations thereof.
摘要翻译： 提供了用于锂离子电化学电池的电极组合物，其包括新的粘合剂。 新型粘合剂包括羧酸和磺酸的多元醇锂，酸的共聚物的锂盐，聚磺酸锂含氟聚合物，固化的酚醛树脂，固化的葡萄糖及其组合。
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公开(公告)号：US07851085B2
公开(公告)日：2010-12-14
申请号：US11387205
申请日：2006-03-23
申请人： Mark N. Obrovac , Leif Christensen
发明人： Mark N. Obrovac , Leif Christensen
CPC分类号： H01M10/0525 , B22F2998/00 , C22C1/002 , C22C1/0416 , C22C1/0491 , C22C28/00 , C22C2200/02 , H01M4/38 , H01M4/382 , H01M4/46 , B22F9/04 , B22F9/08
摘要： Alloy compositions, lithium ion batteries, and methods of making lithium ion batteries are described. The lithium ion batteries have anodes that contain an alloy composition that includes a) silicon, b) aluminum, c) transition metal, d) tin, and e) a fifth element that contains yttrium, a lanthanide element, an actinide element, or a combination thereof. The alloy composition is a mixture of an amorphous phase that includes silicon and a nanocrystalline phase that includes an intermetallic compound of tin and the fifth element.
摘要翻译： 描述了合金组成，锂离子电池和制造锂离子电池的方法。 锂离子电池具有包含a）硅，b）铝，c）过渡金属，d）锡和e）第五元素的合金组成的阳极，其包含钇，镧系元素，锕系元素或 的组合。 合金组成是包括硅和纳米晶相的非晶相的混合物，其包括锡的金属间化合物和第五元素。
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