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公开(公告)号:US20110264707A1
公开(公告)日:2011-10-27
申请号:US12767704
申请日:2010-04-26
IPC分类号: G06F17/30
摘要: A method for capturing patterns and associated points of variability includes providing an XML schema defining elements representing different point of variability (POV) types for a pattern. The elements belong to an XML schema “substitution group” to enable the POV types to be substituted for one another. In selected embodiments, the method enables a pattern author to add new or custom POV types to the “substitution group,” thereby allowing the pattern author to extend the pattern meta model to include new POV types. Once the desired POV types are defined, the method enables the pattern author to generate an instance of the XML schema, defining the points of variability for a specific pattern, using the elements defined in the XML schema “substitution group.” A corresponding apparatus and computer program product are also disclosed and claimed herein.
摘要翻译: 用于捕获模式和相关联的可变性点的方法包括提供定义表示模式的不同变异点(POV)类型的元素的XML模式。 这些元素属于一个XML模式“替换组”,以使得POV类型可以互相替代。 在所选择的实施例中,该方法使得模式作者能够向“替换组”添加新的或定制的POV类型,从而允许模式作者将模式元模型扩展以包括新的POV类型。 一旦定义了所需的POV类型,该方法使得模式作者能够使用XML模式“替换组”中定义的元素来生成XML模式的实例,以定义特定模式的变异点。对应的设备和 本文还公开并要求保护计算机程序产品。
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公开(公告)号:US09244659B2
公开(公告)日:2016-01-26
申请号:US12767704
申请日:2010-04-26
摘要: A method for capturing patterns and associated points of variability includes providing an XML schema defining elements representing different point of variability (POV) types for a pattern. The elements belong to an XML schema “substitution group” to enable the POV types to be substituted for one another. In selected embodiments, the method enables a pattern author to add new or custom POV types to the “substitution group,” thereby allowing the pattern author to extend the pattern meta model to include new POV types. Once the desired POV types are defined, the method enables the pattern author to generate an instance of the XML schema, defining the points of variability for a specific pattern, using the elements defined in the XML schema “substitution group.” A corresponding apparatus and computer program product are also disclosed and claimed herein.
摘要翻译: 用于捕获模式和相关联的可变性点的方法包括提供定义表示模式的不同变异点(POV)类型的元素的XML模式。 这些元素属于一个XML模式“替换组”,以使得POV类型可以互相替代。 在所选择的实施例中,该方法使得模式作者能够向“替换组”添加新的或定制的POV类型,从而允许模式作者将模式元模型扩展以包括新的POV类型。 一旦定义了所需的POV类型,该方法使得模式作者能够使用XML模式“替换组”中定义的元素来生成XML模式的实例,以定义特定模式的变异点。对应的设备和 本文还公开并要求保护计算机程序产品。
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公开(公告)号:US20140032739A1
公开(公告)日:2014-01-30
申请号:US13557651
申请日:2012-07-25
IPC分类号: G06F15/173
摘要: The present invention provides a method, system and computer program product for watch list oriented processing of events in a multi-object event data processing system. In an embodiment of the invention, a method for watch list oriented processing of events in a multi-object event data processing system, can include pre-processing a set of subscriptions against a pool of objects monitored for events in the data processing system to produce a watch list of objects. The method further can include receiving events in the data processing system corresponding to different ones of the objects in the pool of objects. The method yet further can include comparing the received events to the watch list to determine which events pertain to objects referenced in the watch list.
摘要翻译: 本发明提供了一种用于在多对象事件数据处理系统中对于事件进行观看列表定向处理的方法,系统和计算机程序产品。 在本发明的一个实施例中,一种用于在多对象事件数据处理系统中对于事件进行观察列表处理的方法,可以包括针对针对数据处理系统中的事件监视的对象池预处理一组订阅以产生 对象的观察列表。 该方法还可以包括在数据处理系统中接收与对象池中的不同对象相对应的事件。 该方法还包括将接收到的事件与观察列表进行比较,以确定哪些事件涉及在观察列表中引用的对象。
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公开(公告)号:US07252968B2
公开(公告)日:2007-08-07
申请号:US10773302
申请日:2004-02-09
申请人: Thomas Jenuwein , Götz Laible , Donal O'Carroll , Frank Eisenhaber , Stephen Rea
发明人: Thomas Jenuwein , Götz Laible , Donal O'Carroll , Frank Eisenhaber , Stephen Rea
CPC分类号: C07K14/4702 , A01K2217/05 , A61K38/00 , Y02A90/22 , Y02A90/26
摘要: The invention concerns the deregulation of the chromatin-regulator genes which have a SET domain, such deregulation being of importance in certain cancer conditions. These genes can be used in the diagnosis and therapy of such conditions.
摘要翻译: 本发明涉及具有SET结构域的染色质调节基因的去调节,这种去调节在某些癌症病症中是重要的。 这些基因可用于诊断和治疗这些病症。
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公开(公告)号:US07052889B2
公开(公告)日:2006-05-30
申请号:US10302904
申请日:2002-11-25
申请人: Thomas Jenuwein , Donal O'Carroll , Stephen Rea
发明人: Thomas Jenuwein , Donal O'Carroll , Stephen Rea
CPC分类号: C12Q1/48 , A61K38/00 , C07K14/4702 , C07K16/40 , C12N9/1007 , G01N33/6875 , G01N2333/91011 , G01N2500/00
摘要: Murine and human Suv39h2 polypeptide and DNA molecules encoding them. Suv39h2 is a novel member of the Suv3-9 gene family. Suv39h2 is a novel component of meiotic higher order chromatin. It has histone methyltransferase activity and is required, in combination with Suv39h1, for male gametogenesis. Suv39h2 can be used in screening methods to identify modulators of its methyltransferase activity, which are useful in cancer therapy and for male contraception.
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公开(公告)号:US20050089880A1
公开(公告)日:2005-04-28
申请号:US10773302
申请日:2004-02-09
申请人: Thomas Jenuwein , Gotz Laible , Donal O'Carroll , Frank Eisenhaber , Stephen Rea
发明人: Thomas Jenuwein , Gotz Laible , Donal O'Carroll , Frank Eisenhaber , Stephen Rea
IPC分类号: A01K67/027 , A61K38/00 , C07K14/47 , C07K16/18 , C12N1/21 , C12N5/10 , C12N15/09 , C12Q1/68 , G01N33/50 , C07H21/04 , C12N9/22
CPC分类号: C07K14/4702 , A01K2217/05 , A61K38/00 , Y02A90/22 , Y02A90/26
摘要: The invention concerns the deregulation of the chromatin-regulator genes which have a SET domain, such deregulation being of importance in certain cancer conditions. These genes can be used in the diagnosis and therapy of such conditions.
摘要翻译: 本发明涉及具有SET结构域的染色质调节基因的去调节,这种去调节在某些癌症病症中是重要的。 这些基因可用于诊断和治疗这些病症。
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公开(公告)号:US10122598B2
公开(公告)日:2018-11-06
申请号:US13557651
申请日:2012-07-25
IPC分类号: G06F15/173 , H04L12/26 , G06F9/54
摘要: The present invention provides a method, system and computer program product for watch list oriented processing of events in a multi-object event data processing system. In an embodiment of the invention, a method for watch list oriented processing of events in a multi-object event data processing system, can include pre-processing a set of subscriptions against a pool of objects monitored for events in the data processing system to produce a watch list of objects. The method further can include receiving events in the data processing system corresponding to different ones of the objects in the pool of objects. The method yet further can include comparing the received events to the watch list to determine which events pertain to objects referenced in the watch list.
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公开(公告)号:US06689583B1
公开(公告)日:2004-02-10
申请号:US09589892
申请日:2000-06-09
申请人: Thomas Jenuwein , Götz Laible , Donal O'Carroll , Frank Eisenhaber , Stephen Rea
发明人: Thomas Jenuwein , Götz Laible , Donal O'Carroll , Frank Eisenhaber , Stephen Rea
IPC分类号: C12P2102
CPC分类号: C07K14/4702 , A01K2217/05 , A61K38/00 , Y02A90/22 , Y02A90/26
摘要: The invention concerns the deregulation of the chromatin-regulator genes which have a SET domain, such deregulation being of importance in certain cancer conditions. These genes can be used in the diagnosis and therapy of such conditions.
摘要翻译: 本发明涉及具有SET结构域的染色质调节基因的去调节,这种去调节在某些癌症病症中是重要的。 这些基因可用于诊断和治疗这些病症。
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9.
公开(公告)号:US06555329B2
公开(公告)日:2003-04-29
申请号:US09876221
申请日:2001-06-08
IPC分类号: C12Q148
CPC分类号: C07K16/40 , C12N9/1007 , C12Q1/48 , G01N33/6875 , G01N2333/91011 , G01N2500/00
摘要: A method for identifying compounds that alter higher order chromatin dependent chromosome stability is based on determining the compounds' ability to modify a methyltransferase with Suv39h-like methyltransferase activity. The identified compounds are useful in therapy, in particular the therapy of human cancer and for contraception.
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