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公开(公告)号:US08906663B2
公开(公告)日:2014-12-09
申请号:US13678884
申请日:2012-11-16
申请人: Verenium Corporation
发明人: David Weiner , Ellen Chi , Jennifer Ann Chaplin , Aileen Milan , Jay M. Short , Grace DeSantis , Mark Madden , Mark J. Burk , Dan E. Robertson
IPC分类号: C12N9/78 , C12N15/00 , C12N1/20 , C12N1/00 , C12N5/00 , C12N1/14 , C12P21/06 , C12P21/04 , C07H21/04 , C12P7/42 , C12N15/81 , C12N15/74 , C12N15/70 , C12P21/00 , C12P13/00 , C12P13/04 , C12P41/00 , C12P7/40
CPC分类号: C12P7/42 , C12N9/78 , C12N15/00 , C12N15/70 , C12N15/74 , C12N15/81 , C12N15/815 , C12P7/40 , C12P13/004 , C12P13/04 , C12P21/00 , C12P41/006
摘要: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
摘要翻译: 本发明涉及腈水解酶和编码腈水解酶的核酸。 另外还提供了设计新腈水解酶的方法及其使用方法。 在增加的pH和温度下,腈水解酶具有增加的活性和稳定性。
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公开(公告)号:US20130177949A1
公开(公告)日:2013-07-11
申请号:US13678884
申请日:2012-11-16
申请人: VERENIUM CORPORATION , Darcy Madden
发明人: David Weiner , Ellen Chi , Jennifer Ann Chaplin , Aileen Milan , Jay M. Short , Grace DeSantis , Mark Madden , Mark J. Burk , Dan E. Robertson
CPC分类号: C12P7/42 , C12N9/78 , C12N15/00 , C12N15/70 , C12N15/74 , C12N15/81 , C12N15/815 , C12P7/40 , C12P13/004 , C12P13/04 , C12P21/00 , C12P41/006
摘要: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
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