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公开(公告)号：US06238655B1
公开(公告)日：2001-05-29
申请号：US08990989
申请日：1997-12-15
IPC分类号： A61K732
CPC分类号： A61Q13/00 , A61K8/44 , A61K2800/57 , A61Q15/00 , C07C233/50 , C07C233/63 , C07C233/83 , C07C235/52 , C07C2601/08
摘要： Disclosed are &agr;-amides of L-amino acids that produce fragrance or attenuate or mask malodor. In particular, threonine amides, glycine amides, serine amides, and alanine amides can be used in the invention. Such &agr;-amides of L-amino acids are useful for generating pleasant fragrances or attenuating or masking malodor upon cleavage of the &agr;-amides of L-amino acids by bacteria in axillae. The &agr;-amides of L-amino acids can be incorporated into skin treatment compositions and personal care products, such as deodorants, body sprays and antiperspirants, and used in methods for producing fragrance or attenuating or masking malodor.
摘要翻译： 公开了产生香味或减弱或掩盖恶臭的L-氨基酸的α-酰胺。 特别地，苏氨酰胺，甘氨酸酰胺，丝氨酰胺和丙氨酸酰胺可用于本发明。 这种L-氨基酸的α-酰胺可用于产生令人愉悦的香味，或在腋窝细菌中切断L-氨基酸的α-酰胺后减弱或掩蔽恶臭。 L-氨基酸的α-酰胺可以并入皮肤处理组合物和个人护理产品中，例如除臭剂，身体喷雾剂和止汗剂，并且用于生产香料或减弱或掩蔽恶臭的方法。
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公开(公告)号：US5932198A
公开(公告)日：1999-08-03
申请号：US990988
申请日：1997-12-15
IPC分类号： A61K8/00 , A61K8/02 , A61K8/04 , A61K8/30 , A61K8/44 , A61K8/49 , A61Q5/00 , A61Q5/02 , A61Q9/02 , A61Q9/04 , A61Q13/00 , A61Q15/00 , A61Q19/00 , A61Q19/10 , C07C205/00 , A61K7/32 , A61K7/00 , A61K7/06 , A61K7/15
CPC分类号： A61Q15/00 , A61K8/02 , A61K8/046 , A61K8/44 , A61K8/492 , A61Q13/00 , A61K2800/57 , A61K2800/77
摘要： Disclosed are .alpha.-amides of L-amino acids that produce fragrance or attenuate or mask malodor. In particular, glutamine and asparagine amides can be used in the invention. Such .alpha.-amides of L-amino acids are useful for generating pleasant fragrances or attenuating or masking malodor upon cleavage of the .alpha.-amides of L-amino acids by bacteria in axillae. The .alpha.-amides of L-amino acids can be incorporated into skin treatment compositions and personal care products, such as deodorants, body sprays and antiperspirants, and used in methods for producing fragrance or attenuating or masking malodor.
摘要翻译： 公开了产生香味或减弱或掩盖恶臭的L-氨基酸的α-酰胺。 特别地，谷氨酰胺和天冬酰胺酰胺可用于本发明。 这种L-氨基酸的α-酰胺可用于产生令人愉悦的香味，或者在腋窝细菌裂解L-氨基酸的α-酰胺后，减弱或掩蔽恶臭。 L-氨基酸的α-酰胺可以并入皮肤处理组合物和个人护理产品中，例如除臭剂，身体喷雾剂和止汗剂，并且用于生产香料或减弱或掩蔽恶臭的方法。
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公开(公告)号：US20120225898A1
公开(公告)日：2012-09-06
申请号：US13471810
申请日：2012-05-15
IPC分类号： A61K31/506 , A61P17/14
CPC分类号： A61K8/4953 , A61K8/361 , A61K8/678 , A61K31/505 , A61K2800/10 , A61Q7/00 , Y10S514/88
摘要： The present disclosure relates to compositions containing certain pyrimidine compounds such as minoxidil and/or certain pyrimidine sulfate (inner salt) compounds such as minoxidil sulfate and especially compositions containing pyrimidine compounds in combination with an admixtures comprising at least one antioxidant, at least one organic acid and a select fatty acid mixture. The present disclosure also relates to use of the compositions to grow and/or regrow hair and/or prevent hair loss in mammals and particularly in humans.
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4.发明申请Methods of Reducing Hair Loss and/or Facilitating Hair Growth and/or Regrowth 有权减少脱发和/或促进头发生长和/或再生长的方法公开(公告)号：US20110144142A1
公开(公告)日：2011-06-16
申请号：US12638142
申请日：2009-12-15
CPC分类号： A61K8/922 , A61K8/044 , A61K8/36 , A61K8/365 , A61K8/4953 , A61K8/678 , A61K8/97 , A61K31/19 , A61K31/20 , A61K31/201 , A61K31/355 , A61K31/375 , A61K31/505 , A61K2800/522 , A61K2800/592 , A61Q7/00 , Y10S514/88
摘要： The present disclosure relates to methods of retarding hair loss or facilitating hair growth and/or regrowth. More specifically, the present disclosure relates to methods of using the disclosed compositions to increase the rate of terminal hair growth and/or regrowth in a mammal.
摘要翻译： 本发明涉及延缓脱发或促进毛发生长和/或再生长的方法。 更具体地，本公开涉及使用所公开的组合物来增加哺乳动物中末梢毛发生长和/或再生长的速率的方法。
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公开(公告)号：US08877762B2
公开(公告)日：2014-11-04
申请号：US13471810
申请日：2012-05-15
CPC分类号： A61K8/4953 , A61K8/361 , A61K8/678 , A61K31/505 , A61K2800/10 , A61Q7/00 , Y10S514/88
摘要： The present disclosure relates to compositions containing certain pyrimidine compounds such as minoxidil and/or certain pyrimidine sulfate (inner salt) compounds such as minoxidil sulfate and especially compositions containing pyrimidine compounds in combination with an admixtures comprising at least one antioxidant, at least one organic acid and a select fatty acid mixture. The present disclosure also relates to use of the compositions to grow and/or regrow hair and/or prevent hair loss in mammals and particularly in humans.
摘要翻译： 本公开内容涉及含有某些嘧啶化合物如米诺地尔和/或某些嘧啶硫酸盐（内盐）化合物如硫酸米诺地尔的组合物，特别是含有嘧啶化合物的组合物与包含至少一种抗氧化剂，至少一种有机酸 和选择性脂肪酸混合物。 本公开还涉及组合物在哺乳动物，特别是人中生长和/或再生毛发和/或预防脱发的用途。
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6.发明授权Methods of reducing hair loss and/or facilitating hair growth and/or regrowth 有权减少脱发和/或促进毛发生长和/或再生长的方法公开(公告)号：US08871773B2
公开(公告)日：2014-10-28
申请号：US13908507
申请日：2013-06-03
CPC分类号： A61K8/922 , A61K8/044 , A61K8/36 , A61K8/365 , A61K8/4953 , A61K8/678 , A61K8/97 , A61K31/19 , A61K31/20 , A61K31/201 , A61K31/355 , A61K31/375 , A61K31/505 , A61K2800/522 , A61K2800/592 , A61Q7/00 , Y10S514/88
摘要： The present disclosure relates to methods of retarding hair loss or facilitating hair growth and/or regrowth. More specifically, the present disclosure relates to methods of using the disclosed compositions to increase the rate of terminal hair growth and/or regrowth in a mammal.
摘要翻译： 本发明涉及延缓脱发或促进毛发生长和/或再生长的方法。 更具体地，本公开涉及使用所公开的组合物来增加哺乳动物中末梢毛发生长和/或再生长的速率的方法。
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公开(公告)号：US08470833B2
公开(公告)日：2013-06-25
申请号：US12638091
申请日：2009-12-15
IPC分类号： A61K31/505 , A61K31/355 , A61K31/34 , A61K31/19
CPC分类号： A61K8/4953 , A61K8/361 , A61K8/678 , A61K31/505 , A61K2800/10 , A61Q7/00 , Y10S514/88
摘要： The present disclosure relates to compositions containing certain pyrimidine compounds such as minoxidil and/or certain pyrimidine sulfate (inner salt) compounds such as minoxidil sulfate and especially compositions containing pyrimidine compounds in combination with an admixtures comprising at least one antioxidant, at least one organic acid and a select fatty acid mixture. The present disclosure also relates to use of the compositions to grow and/or regrow hair and/or prevent hair loss in mammals and particularly in humans.
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公开(公告)号：US20080128425A1
公开(公告)日：2008-06-05
申请号：US11607384
申请日：2006-12-01
申请人： Donald Rick , Ammunje S. Nayak , Gurpreet Bhathal , Susan Wendling , Virginia Streusand Goldman
发明人： Donald Rick , Ammunje S. Nayak , Gurpreet Bhathal , Susan Wendling , Virginia Streusand Goldman
CPC分类号： A61K9/0014 , A61K8/02 , A61K8/26 , A61K2800/242 , A61K2800/88 , A61Q19/00
摘要： The present invention contemplates a dual warming and analgesic composition comprising a hydrous portion comprising water and an anhydrous portion comprising a zeolite a carrier and a suspending or dispersing agent, wherein the anhydrous portion and the hydrous portion are combined in use to provide warming and analgesic effects without the addition of external water.
摘要翻译： 本发明涉及一种双重升温和止痛组合物，其包含含水的含水部分和包含沸石的载体和悬浮剂或分散剂的无水部分，其中所述无水部分和所述含水部分在使用中组合以提供加温和止痛效果 不加外界水。
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公开(公告)号：US20110144141A1
公开(公告)日：2011-06-16
申请号：US12638091
申请日：2009-12-15
IPC分类号： A61K31/505 , A61P17/00
CPC分类号： A61K8/4953 , A61K8/361 , A61K8/678 , A61K31/505 , A61K2800/10 , A61Q7/00 , Y10S514/88
摘要： The present disclosure relates to compositions containing certain pyrimidine compounds such as minoxidil and/or certain pyrimidine sulfate (inner salt) compounds such as minoxidil sulfate and especially compositions containing pyrimidine compounds in combination with an admixtures comprising at least one antioxidant, at least one organic acid and a select fatty acid mixture. The present disclosure also relates to use of the compositions to grow and/or regrow hair and/or prevent hair loss in mammals and particularly in humans.
摘要翻译： 本公开内容涉及含有某些嘧啶化合物如米诺地尔和/或某些嘧啶硫酸盐（内盐）化合物如硫酸米诺地尔的组合物，特别是含有嘧啶化合物的组合物与包含至少一种抗氧化剂，至少一种有机酸 和选择性脂肪酸混合物。 本公开还涉及组合物在哺乳动物，特别是人中生长和/或再生毛发和/或预防脱发的用途。
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公开(公告)号：US06569411B2
公开(公告)日：2003-05-27
申请号：US10219964
申请日：2002-08-15
IPC分类号： A61K732
CPC分类号： A61Q13/00 , A61K8/02 , A61K8/046 , A61K8/26 , A61K8/28 , A61K8/44 , A61K8/585 , A61K2800/57 , A61K2800/77 , A61Q15/00 , A61Q17/005 , C07C229/22 , C07C229/28 , C07C229/36 , C07C233/47 , C07C271/22 , C07C2601/14 , C07F7/081 , C07J41/0055
摘要： Serine carbonates of formula I are precursors for organoleptic compounds, masking agents and antimicrobial agents. Further they are alternative substrates for malodor producing enzymes. The symbols in formula I are defined in claim 1.
摘要翻译： 式I的丝氨酸碳酸酯是感官化合物，掩蔽剂和抗微生物剂的前体。 此外，它们是产生恶臭的酶的替代底物。 式I中的符号在权利要求1中定义。
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