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    Fluid vaporizing device having controlled temperature profile heater/capillary tube
    1.
    发明授权
    Fluid vaporizing device having controlled temperature profile heater/capillary tube 有权

    公开(公告)号：US06640050B2

    公开(公告)日：2003-10-28

    申请号：US09957026

    申请日：2001-09-21

    申请人： Walter A. Nichols ,  Kenneth A. Cox ,  Douglas D. McRae ,  Tung Tien Nguyen

    发明人： Walter A. Nichols ,  Kenneth A. Cox ,  Douglas D. McRae ,  Tung Tien Nguyen

    IPC分类号： F24F600

    CPC分类号： A61M11/041 ,  A61M11/001 ,  A61M11/007 ,  A61M11/042 ,  A61M15/025 ,  A61M2016/0021 ,  A61M2205/8206

    摘要： A fluid vaporizing device useful for vaporizing fluid into an aerosol includes a capillary tube made from an electrically conductive material, an upstream electrode connected to the tube, and a downstream electrode connected to the tube and provided with an electrical resistivity sufficient to cause heating of the downstream electrode during operation to approximately the same temperature as the tube at the point of connection. The upstream and downstream electrodes connected to the capillary tube divide the tube into an initial feed section, a heated section, and a tip. A source of material to be volatilized is provided to the tube at the feed section, passes downstream into the heated section, is vaporized, and then exits from the tube through the tip. The temperature profile of the tube along the heated section is controlled by varying parameters to substantially eliminate any effect of the downstream electrode as a heat sink. These parameters may include the electrical resistivity of the downstream electrode, its cross-sectional area, and its length.

    Dual capillary fluid vaporizing device
    2.
    发明授权
    Dual capillary fluid vaporizing device 有权
    双毛细管流体蒸发装置

    公开(公告)号：US06715487B2

    公开(公告)日：2004-04-06

    申请号：US10430272

    申请日：2003-05-07

    申请人： Walter A. Nichols ,  Kenneth A. Cox ,  Tung Tien Nguyen

    发明人： Walter A. Nichols ,  Kenneth A. Cox ,  Tung Tien Nguyen

    IPC分类号： A61M1500

    CPC分类号： A61M15/00 ,  A61M11/007 ,  A61M11/042 ,  A61M15/025 ,  A61M2016/0024

    摘要： A fluid vaporizing device useful for vaporizing fluid into an aerosol and includes first and second capillary tubes connected electrically in series by providing separate electrodes at the inlet ends of each capillary tube, and connecting the outlet ends of the capillary tubes by an electrical connection that connects the outlet ends both electrically and thermally. The capillary tubes are heated by the flow of electricity therethrough, and liquid flowing through the tubes is vaporized. The outlet ends of the capillary tubes are easily maintained at a temperature for optimizing aerosol generation since there is minimal heat loss through the connection connecting the outlet ends.

    摘要翻译： 一种流体蒸发装置，其用于将流体蒸发成气溶胶，并且包括通过在每个毛细管的入口端处提供分开的电极串联电连接的第一和第二毛细管，并且通过电连接连接毛细管的出口端，该电连接 出口端部电气和热端都结束。 毛细管由电流通过其加热，流过管的液体被蒸发。 毛细管的出口端容易地保持在用于优化气溶胶产生的温度，因为通过连接出口端的连接件具有最小的热损失。

    Dual capillary fluid vaporizing device
    3.
    发明授权
    Dual capillary fluid vaporizing device 有权
    双毛细管流体蒸发装置

    公开(公告)号：US06568390B2

    公开(公告)日：2003-05-27

    申请号：US09956966

    申请日：2001-09-21

    申请人： Walter A. Nichols ,  Kenneth A. Cox ,  Tung Tien Nguyen

    发明人： Walter A. Nichols ,  Kenneth A. Cox ,  Tung Tien Nguyen

    IPC分类号： A61M1500

    CPC分类号： A61M15/00 ,  A61M11/007 ,  A61M11/042 ,  A61M15/025 ,  A61M2016/0024

    摘要： A fluid vaporizing device useful for vaporizing fluid into an aerosol and includes first and second capillary tubes connected electrically in series by providing separate electrodes at the inlet ends of each capillary tube, and connecting the outlet ends of the capillary tubes by an electrical connection that connects the outlet ends both electrically and thermally. The capillary tubes are heated by the flow of electricity therethrough, and liquid flowing through the tubes is vaporized. The outlet ends of the capillary tubes are easily maintained at a temperature for optimizing aerosol generation since there is minimal heat loss through the connection connecting the outlet ends.

    摘要翻译： 一种流体蒸发装置，其用于将流体蒸发成气溶胶，并且包括通过在每个毛细管的入口端处提供分开的电极串联电连接的第一和第二毛细管，并且通过电连接连接毛细管的出口端，该电连接 出口端部电气和热端都结束。 毛细管由电流通过其加热，流过管的液体被蒸发。 毛细管的出口端容易地保持在用于优化气溶胶产生的温度，因为通过连接出口端的连接件具有最小的热损失。

    Methods and apparatus for producing nanoscale particles
    8.
    发明申请
    Methods and apparatus for producing nanoscale particles 有权
    制备纳米级颗粒的方法和装置

    公开(公告)号：US20080268060A1

    公开(公告)日：2008-10-30

    申请号：US12149604

    申请日：2008-05-05

    申请人： Tung T. Nguyen ,  Nina Brown ,  Jui C. Lin ,  Stephen Pham ,  Kenneth A. Cox ,  Douglas D. McRae ,  Walter A. Nichols

    发明人： Tung T. Nguyen ,  Nina Brown ,  Jui C. Lin ,  Stephen Pham ,  Kenneth A. Cox ,  Douglas D. McRae ,  Walter A. Nichols

    IPC分类号： A61K9/14 ,  A61K31/58 ,  A61K31/137

    CPC分类号： A61K31/137 ,  A61K9/0073 ,  A61K31/573 ,  A61K47/08 ,  A61K47/10 ,  A61M11/041 ,  A61M11/042 ,  A61M15/0025 ,  A61M15/025 ,  A61M2016/0021 ,  A61M2205/8206 ,  A61M2205/8237

    摘要： Liquid nanoscale particle precursor materials for generating nanoscale particles include at least one high volatility carrier and a second component. A nanoscale particle generating device generates nanoscale particles by passing a liquid nanoscale particle precursor material through a flow passage heated to convert the carrier into a vapor and the second component into nanoscale particles. The nanoscale particles preferably consist essentially of the second component and can consist essentially of dry, solid particles. The particle generator can be incorporated in a hand held inhaler, and can be delivered to a targeted portion of the lung using the inhaler. Composite controlled release particles of micron or nanoscale size can be produced by flowing a solution of medicament, control release agent and carrier liquid through a capillary heater.

    摘要翻译： 用于产生纳米尺寸颗粒的液体纳米级颗粒前体材料包括至少一种高挥发性载体和第二组分。 纳米级粒子产生装置通过使液体纳米级粒子前体材料通过加热的流动通道将载体转化为蒸气并将第二组分转变为纳米级颗粒而产生纳米级颗粒。 纳米尺度颗粒优选基本上由第二组分组成，并且可以基本上由干燥的固体颗粒组成。 颗粒发生器可以并入手持式吸入器中，并且可以使用吸入器输送到肺的目标部分。 可以通过使药物，控制释放剂和载液的溶液流过毛细管加热器来生产微米或纳米尺寸的复合控制释放颗粒。