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公开(公告)号：US4625041A
公开(公告)日：1986-11-25
申请号：US770472
申请日：1985-08-29
IPC分类号： A23K20/195 , C07H19/01 , C12P19/44 , C12P19/60 , C07D309/10
CPC分类号： C07H19/01 , A23K20/195 , C12P19/445 , C12P19/60 , C12R1/465
摘要： A new acidic polycyclic ether antibiotic, CP-63,517, having the formula: ##STR1## and cationic salts thereof produced by submerged aerobic propagation of Streptomyces endus subsp. aureus, ATCC-39574, a new strain of microorganism isolated from a soil sample in Japan, a process for producing this antibiotic and methods for its use to improve feed utilization, promote growth of cattle and swine and to control coccidiosis.
摘要翻译： 一种新的酸性多环醚抗生素CP-63,517，具有下式：其中通过唾液链霉菌（Streptomyces endus subsp。）的浸没有氧繁殖产生的阳离子盐。 金黄色葡萄球菌ATCC-39574是从日本土壤样品中分离的新菌株，该抗生素的生产方法及其用于改善饲料利用，促进牛和猪生长以及控制球虫病的方法。
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2.发明授权
公开(公告)号：US4543334A
公开(公告)日：1985-09-24
申请号：US562784
申请日：1983-12-16
CPC分类号： C07H17/08 , C12P19/62 , C12R1/465 , Y10S435/886
摘要： An antibiotic complex, consisting of one major and two minor components, has been isolated from fermentation of a new Streptomyces culture. The components from the complex are three new macrolides which are active as antibacterial agents against certain gram-negative and gram-positive microorganisms.
摘要翻译： 由一种主要和两个次要组分组成的抗生素复合物已经从新的链霉菌培养物的发酵中分离出来。 来自该复合物的组分是三种新的大环内酯类，其作为针对某些革兰氏阴性和革兰氏阳性微生物的抗菌剂是有活性的。
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公开(公告)号：US4707493A
公开(公告)日：1987-11-17
申请号：US931587
申请日：1986-11-17
IPC分类号： C07H19/01 , C12P19/44 , C12P19/60 , C07D309/10
CPC分类号： C07H19/01 , C12P19/445 , C12P19/60 , C12R1/55
摘要： Antibiotic 19-epi-dianemycin, process for its preparation by fermenting a new strain of Streptomyces hygroscopicus, and isolation from the fermentation broth; and its use as an anticoccidial agent and antibacterial agent against gram-positive bacteria.
摘要翻译： 抗生素19-epi-dianemycin，其制备方法是通过发酵新的吸水链霉菌菌株和从发酵液中分离; 并作为抗球虫剂和抗革兰氏阳性菌的抗菌剂使用。
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公开(公告)号：US4547523A
公开(公告)日：1985-10-15
申请号：US549378
申请日：1983-11-07
IPC分类号： C07D493/10 , C12P17/18 , C07D263/56
CPC分类号： C07D493/10 , C12P17/181 , Y10S435/886
摘要： A new polyether antibiotic has been isolated from fermentations of a new microorganism of the genus Streptomyces. This new microorganism is designated as N478-13 and it has ben named Streptomyces routienii Huang sp. nov., (ATCC 39446). The new antibiotic exhibits antibacterial activity against a variety of gram-positive bacteria; it can be used to control swine dysentery; and it promotes increased efficiency of feed utilization (i.e. promotes increased growth) in swine and ruminants.
摘要翻译： 已经从链霉菌属的新微生物的发酵中分离出新的聚醚抗生素。 这种新的微生物被指定为N478-13，它具有本命名为Streptomyces routienii Huang sp。 nov。，（ATCC 39446）。 新型抗生素对各种革兰氏阳性菌具有抗菌活性; 可用于控制猪痢疾; 并且促进猪和反刍动物饲料利用效率提高（即促进生长增长）。
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公开(公告)号：US4652523A
公开(公告)日：1987-03-24
申请号：US660619
申请日：1984-10-15
IPC分类号： C07D493/10 , C12P17/18 , C12R1/465
CPC分类号： C07D493/10 , C12P17/181 , Y10S435/886
摘要： A new polyether antibiotic has been isolated from fermentations of a new microorganism of the genus Streptomyces. This new microorganism is designated as N478-13 and it has been named Streptomyces routienii Huange sp. nov., (ATCC 30446). The new antibiotic exhibits antibacterial activity against a variety of gram-positive bacteria; it can be used to control swine dysentery; and it promotes increased efficiency of feed utilization (i.e. promotes increased growth) in swine and ruminants.
摘要翻译： 已经从链霉菌属的新微生物的发酵中分离出新的聚醚抗生素。 这种新的微生物被命名为N478-13，它被命名为Streptomyces routienii Huange sp。 （ATCC 30446）。 新型抗生素对各种革兰氏阳性菌具有抗菌活性; 可用于控制猪痢疾; 并且促进猪和反刍动物饲料利用效率提高（即促进生长增长）。
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6.发明授权Process for producing an acidic polycyclic ether antibiotic by cultivation of a novel strain of Streptomyces endus subspecies aureus 失效通过培养新型链霉菌属亚种金黄色葡萄球菌生产酸性多环醚抗生素的方法
公开(公告)号：US4552843A
公开(公告)日：1985-11-12
申请号：US581384
申请日：1984-02-17
IPC分类号： C07D519/00 , A23K1/16 , A23K1/17 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P3/00 , C07H17/04 , C07H19/01 , C12N1/20 , C12P1/00 , C12P17/18 , C12P19/00 , C12P19/44 , C12P19/60 , C12R1/465 , C12P19/62
CPC分类号： C07H19/01 , A23K20/195 , C12P19/445 , C12P19/60 , C12R1/465 , Y10S435/886
摘要： A new acidic polycyclic ether antibiotic, CP-63,517, having the formula: ##STR1## and cationic salts thereof produced by submerged aerobic propagation of Streptomyces endus subsp. aureus, ATCC-39574, a new strain of microorganism isolated from a soil sample in Japan, a process for producing this antibiotic and methods for its use to improve feed utilization, promote growth of cattle and swine and to control coccidiosis.
摘要翻译： 一种新的酸性多环醚抗生素CP-63,517，具有下式：其中通过唾液链霉菌（Streptomyces endus subsp。）的淹没有氧繁殖产生的阳离子盐。 金黄色葡萄球菌ATCC-39574是从日本土壤样品中分离的新菌株，该抗生素的生产方法及其用于改善饲料利用，促进牛和猪生长以及控制球虫病的方法。
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公开(公告)号：US4287182A
公开(公告)日：1981-09-01
申请号：US165407
申请日：1980-07-02
申请人： Walter D. Celmer , Walter P. Cullen , Liang H. Huang , John R. Oscarson , Riichiro Shibakawa , Junsuke Tone
发明人： Walter D. Celmer , Walter P. Cullen , Liang H. Huang , John R. Oscarson , Riichiro Shibakawa , Junsuke Tone
CPC分类号： C12P1/06
摘要： Antibiotics CP-54,715 and CP-54,716, identified by their analytical characteristics, are produced by fermentation of a new microbial species Catenuloplanes jaonicus in a new genus Catenuloplanes and are active against gram-positive and anaerobic infections.
摘要翻译： 通过其分析特征鉴定的抗生素CP-54,715和CP-54,716是通过在新型的猫油平板中发酵新的微生物种类的种子来生产的，并且对革兰氏阳性和厌氧感染具有活性。
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公开(公告)号：US4533553A
公开(公告)日：1985-08-06
申请号：US549912
申请日：1983-11-09
IPC分类号： C07H19/01 , C12P17/18 , A61K31/00 , A61K31/35 , C07D309/10 , C07D309/22
CPC分类号： C07H19/01 , C12P17/181 , C12R1/465
摘要： Growth of cattle and swine is promoted and feed utilization efficiency increased by an improved nutrient feed containing the antibiotic of the formula ##STR1##
摘要翻译： 促进牛和猪的生长，饲料利用效率由含有下式的抗生素的改良营养饲料提高：+图像>
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公开(公告)号：US4195079A
公开(公告)日：1980-03-25
申请号：US7901
申请日：1979-01-31
申请人： Walter D. Celmer , Walter P. Cullen , John R. Oscarson , Liang H. Huang , Riichiro Shibakawa , Junsuke Tone
发明人： Walter D. Celmer , Walter P. Cullen , John R. Oscarson , Liang H. Huang , Riichiro Shibakawa , Junsuke Tone
IPC分类号： A23K20/195 , C12P1/06 , C12P17/18 , A61K35/00
CPC分类号： C12R1/03 , A23K20/195 , C12P1/06 , C12P17/181 , Y10S435/825
摘要： A new polycyclic ether antibiotic produced by a strain of Actinomadura verrucosospora under submerged fermentation conditions is useful in controlling coccidiosis in poultry and in improving feed utilization efficiency in ruminants.
摘要翻译： 在浸没发酵条件下，由放线菌（Actinomadura verrucosospora）生产的新型多环醚抗生素可用于控制家禽中的球虫病，提高反刍动物饲料利用效率。
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公开(公告)号：US4169887A
公开(公告)日：1979-10-02
申请号：US930399
申请日：1978-08-02
申请人： Walter D. Celmer , Walter P. Cullen , Charles E. Moppett , Mark T. Jefferson , Liang H. Huang , Riichiro Shibakawa , Junsuke Tone
发明人： Walter D. Celmer , Walter P. Cullen , Charles E. Moppett , Mark T. Jefferson , Liang H. Huang , Riichiro Shibakawa , Junsuke Tone
CPC分类号： C12P1/06 , Y10S435/827
摘要： A species of Actinoplanes, designated Actinoplanes deccanensis Parenti, Pagani and Beretta subsp. salmoneus Huang subsp. nov., ATCC 31355, when subjected to submerged aerobic fermentation, produces a new antibiotic complex. Methods for the recovery and purification of the antibiotic complex and some of the individual antibiotic components are described.
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