-
1.发明授权Denaturant stable and/or protease resistant, chaperone-like oligomeric proteins, polynucleotides encoding same, their uses and methods of increasing a specific activity thereof 有权变性剂稳定和/或蛋白酶抗性，伴侣样寡聚蛋白，编码它们的多核苷酸，其用途和提高其比活性的方法公开(公告)号：US07253341B2
公开(公告)日：2007-08-07
申请号：US10233409
申请日：2002-09-04
申请人： Wangxia Wang , Dan Pelah , Tal Alegrand , Yehonathan Pouny , Ira Marton , Amnon Wolf , Oded Shoseyov , Arie Altman
发明人： Wangxia Wang , Dan Pelah , Tal Alegrand , Yehonathan Pouny , Ira Marton , Amnon Wolf , Oded Shoseyov , Arie Altman
CPC分类号： C12P21/02 , A61K38/00 , C07K14/415 , C07K2319/00 , C07K2319/20 , C07K2319/35 , C12N9/96 , C12N15/62 , C12N15/8257 , C12N15/8271 , C12N15/8273
摘要： Novel denaturant-stable, protease resistant, homo-oligomeric proteins, also referred to herein as stable proteins (SPs), having chaperone-like activity; methods of production and purification of SPs; nucleic acids encoding SPs; methods of isolating nucleic acids encoding SPs; antibodies recognizing SPs; the use of SPs for stabilizing, refolding, repairing, preventing aggregation and de-aggregating macromolecules such as proteins; fusion proteins including SPs; nucleic acid constructs encoding the fusion proteins; and their uses in a variety of methods and applications.
摘要翻译： 新型变性剂稳定，蛋白酶抗性，同源寡聚蛋白，本文也称为具有伴侣样活性的稳定蛋白（SP）; SP的生产和净化方法; 编码SP的核酸; 分离编码SP的核酸的方法; 识别SP的抗体; 使用SP来稳定，重折叠，修复，防止聚集和聚集大分子如蛋白质; 融合蛋白包括SP; 编码融合蛋白的核酸构建体; 及其在各种方法和应用中的应用。
-
公开(公告)号：US09051379B2
公开(公告)日：2015-06-09
申请号：US11988314
申请日：2006-07-09
申请人： Amnon Wolf , Yehonathan Pouny , Ira Marton , Or Dgany , Arie Altman , Oded Shoseyov
发明人： Amnon Wolf , Yehonathan Pouny , Ira Marton , Or Dgany , Arie Altman , Oded Shoseyov
IPC分类号： A61K38/00 , C07K1/00 , C07K14/415 , A61K38/17 , B82Y30/00
CPC分类号： A61K47/48246 , A61K38/17 , A61K47/48884 , A61K47/64 , A61K47/6929 , B82Y30/00 , C07K14/415
摘要： SP1 and modified SP1 variant polypeptides capable of forming reversible molecular associations with substances, compositions-of-matter comprising same, and uses thereof are provided.
摘要翻译： 提供了能够与物质形成可逆分子缔合的SP1和修饰的SP1变体多肽，包含其的物质组合物及其用途。
-
3.发明申请Denaturat stable and/or protease resistant, chaperone-like oligomeric proteins, polynucleotides encoding same and their uses 审中-公开变性稳定和/或蛋白酶抗性，伴侣样寡聚蛋白，编码它们的多核苷酸及其用途公开(公告)号：US20050074763A1
公开(公告)日：2005-04-07
申请号：US10468841
申请日：2002-03-05
申请人： Wangxia Wang , Dan Pelah , Tal Alegrand , Oded Shoseyov , Arie Altman
发明人： Wangxia Wang , Dan Pelah , Tal Alegrand , Oded Shoseyov , Arie Altman
CPC分类号： C12N9/96 , A61K38/00 , C07K14/415 , C07K2319/00 , C07K2319/35 , C12N15/8271
摘要： Novel denaturant-stable, protease resistant, homo-oligomeric proteins, also referred to herein as stable proteins (SPs), having chaperone-like activity; methods of production and purification of SPs; nucleic acids encoding SPs; methods of isolating nucleic acids encoding SPs; antibodies recognizing SPs; the use of SPs for stabilizing, refolding, repairing, preventing aggregation and de-aggregating macromolecules such as proteins; fusion proteins including SPs; nucleic acid constructs encoding the fusion proteins; and their uses in a variety of methods and applications.
摘要翻译： 新型变性剂稳定，蛋白酶抗性，同源寡聚蛋白，本文也称为具有伴侣样活性的稳定蛋白（SP）; SP的生产和净化方法; 编码SP的核酸; 分离编码SP的核酸的方法; 识别SP的抗体; 使用SP来稳定，重折叠，修复，防止聚集和聚集大分子如蛋白质; 融合蛋白包括SP; 编码融合蛋白的核酸构建体; 及其在各种方法和应用中的应用。
-
公开(公告)号：US20090062197A1
公开(公告)日：2009-03-05
申请号：US11988314
申请日：2006-07-09
申请人： Amnon Wolf , Yenonathan Pouny , Ira Marton , Or Dgany , Arie Altman , Oded Shoseyov
发明人： Amnon Wolf , Yenonathan Pouny , Ira Marton , Or Dgany , Arie Altman , Oded Shoseyov
IPC分类号： A61K38/17 , C07K14/435 , A61P43/00 , C07H21/00
CPC分类号： A61K47/48246 , A61K38/17 , A61K47/48884 , A61K47/64 , A61K47/6929 , B82Y30/00 , C07K14/415
摘要： SP1 and modified SP1 variant polypeptides capable of forming reversible molecular associations with substances, compositions-of-matter comprising same, and uses thereof are provided.
摘要翻译： 提供了能够与物质形成可逆分子缔合的SP1和修饰的SP1变体多肽，包含其的物质组合物及其用途。
-
-
-
搜索结果
4 条记录 (耗时 0.042 秒)
