公开(公告)号：US20210229119A1

公开(公告)日：2021-07-29

申请号：US17155462

申请日：2021-01-22

Applicant: Waters Technologies Corporation

Inventor： Wade P. Leveille ,  Joseph D. Michienzi ,  Jeffrey Musacchio ,  Emrys Jones ,  Steven Derek Pringle ,  Stephen Hattan ,  Gregory T. Roman

IPC: B05B5/03 ,  B05B12/32

Abstract: A sprayer assembly for an ion source is disclosed. The sprayer includes a capillary having an outlet, a sheath for the capillary, and an elastic member. The sheath can move relative to the capillary between a first position in which the sheath covers the outlet of the capillary and a second position in which the outlet of the capillary is exposed. When the sheath moves from the first position to or towards the second position, the elastic member provides a restoring force that acts to restore the position of the sheath to or towards the first position.

公开(公告)号：US20240033756A1

公开(公告)日：2024-02-01

申请号：US18467937

申请日：2023-09-15

Applicant: Waters Technologies Corporation

Inventor： Wade P. Leveille ,  Joseph D. Michienzi ,  Jeffrey Musacchio ,  Emrys Jones ,  Steven Derek Pringle ,  Stephen Hattan ,  Gregory T. Roman

IPC: B05B5/03 ,  B05B12/32

CPC classification number: B05B5/03 ,  B05B12/32

Abstract: A sprayer assembly for an ion source is disclosed. The sprayer includes a capillary having an outlet, a sheath for the capillary, and an elastic member. The sheath can move relative to the capillary between a first position in which the sheath covers the outlet of the capillary and a second position in which the outlet of the capillary is exposed. When the sheath moves from the first position to or towards the second position, the elastic member provides a restoring force that acts to restore the position of the sheath to or towards the first position.

公开(公告)号：US20210300965A1

公开(公告)日：2021-09-30

申请号：US17211092

申请日：2021-03-24

Applicant: Waters Technologies Corporation

Inventor： Jennifer M. Nguyen ,  Matthew A. Lauber ,  Yun Wang Alelyunas ,  Gregory T. Roman ,  Henry Y. Shion

IPC: C07K1/18 ,  B01D53/10

Abstract: The present disclosure provides devices, systems, kits and methods useful for quantitation of biomolecules such as intact proteins and nucleic acids.

公开(公告)号：US20180246087A1

公开(公告)日：2018-08-30

申请号：US15905935

申请日：2018-02-27

Applicant: Waters Technologies Corporation

Inventor： Gregory T. Roman ,  James P. Murphy

IPC: G01N33/543 ,  G01N21/33

CPC classification number: G01N33/54346 ,  G01N21/33 ,  G01N33/6848 ,  G01N33/6851

Abstract: The present disclosure relates devices and methods for analyzing intact antibodies, antibody subunits, antibody drug conjugate subunits, antibody drug conjugates, and intact proteins in a biological mixture.

公开(公告)号：US12077560B2

公开(公告)日：2024-09-03

申请号：US17211092

申请日：2021-03-24

Applicant: Waters Technologies Corporation

Inventor： Jennifer M. Nguyen ,  Matthew A. Lauber ,  Yun Wang Alelyunas ,  Gregory T. Roman ,  Henry Y. Shion

IPC: B01L3/00 ,  A23C9/146 ,  B01D53/10 ,  B01F23/00 ,  B01F23/41 ,  B01F101/23 ,  B23Q17/24 ,  C07K1/18 ,  C12M1/34 ,  C12Q1/04 ,  C12Q1/18 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/39 ,  G01N21/45 ,  G01N21/64 ,  G01N30/12 ,  G01N30/68 ,  G01N30/70 ,  G01N30/72 ,  G01N30/88 ,  G01N33/00 ,  G01N33/18 ,  G01N33/50 ,  G01N33/68

CPC classification number: C07K1/18 ,  B01D53/10 ,  A23C9/1465 ,  C12Q2547/101

Abstract: The present disclosure provides devices, systems, kits and methods useful for quantitation of biomolecules such as intact proteins and nucleic acids.

公开(公告)号：US11794200B2

公开(公告)日：2023-10-24

申请号：US17155462

申请日：2021-01-22

Applicant: Waters Technologies Corporation

Inventor： Wade P. Leveille ,  Joseph D. Michienzi ,  Jeffrey Musacchio ,  Emrys Jones ,  Steven Derek Pringle ,  Stephen Hattan ,  Gregory T. Roman

IPC: B05B5/03 ,  B05B12/32

CPC classification number: B05B5/03 ,  B05B12/32

Abstract: A sprayer assembly for an ion source is disclosed. The sprayer includes a capillary having an outlet, a sheath for the capillary, and an elastic member. The sheath can move relative to the capillary between a first position in which the sheath covers the outlet of the capillary and a second position in which the outlet of the capillary is exposed. When the sheath moves from the first position to or towards the second position, the elastic member provides a restoring force that acts to restore the position of the sheath to or towards the first position.

公开(公告)号：US11092597B2

公开(公告)日：2021-08-17

申请号：US15905935

申请日：2018-02-27

Applicant: Waters Technologies Corporation

Inventor： Gregory T. Roman ,  James P. Murphy

IPC: G01N33/68 ,  G01N33/543 ,  G01N21/33

Abstract: The present disclosure relates devices and methods for analyzing intact antibodies, antibody subunits, antibody drug conjugate subunits, antibody drug conjugates, and intact proteins in a biological mixture.