公开(公告)号：US20220221074A1

公开(公告)日：2022-07-14

申请号：US17569744

申请日：2022-01-06

申请人： Waters Technologies Corporation

发明人： Sean Eric Anderson ,  Wade P. Leveille

IPC分类号： F16K15/18 ,  F16K31/06

摘要： Described is an active check valve that uses electro-magnetic actuation for operation. The valve includes a plunger assembly having a magnet in a sealed internal volume. The plunger assembly further includes a plunger tip that extends from either a plunger assembly housing or a sealing member. Although the plunger assembly is disposed in the solvent flow, the magnet is not exposed to the solvent. When the valve is actuated, the plunger tip moves the sealing member to open or close the valve. Optionally, an arming force may be applied to the sealing member in advance of opening or closing to reduce the subsequent additional force necessary to move the sealing member during opening or closing, thereby improving the accuracy of the solvent composition in liquid chromatography system applications.

公开(公告)号：US20210396721A1

公开(公告)日：2021-12-23

申请号：US17354234

申请日：2021-06-22

申请人： Waters Technologies Corporation

发明人： Michael O. Fogwill ,  Martin Gilar ,  Joseph D. Michienzi ,  Wade P. Leveille ,  Geoff C. Gerhardt ,  Jeffrey Musacchio ,  Jason F. Hill ,  Sylvain G. Cormier

IPC分类号： G01N30/46 ,  G01N30/32 ,  G01N30/30

摘要： The exemplary embodiments may provide a collective insulating sleeve for a plurality of chromatography columns or may provide separate insulating sleeve for each of the chromatography columns in a plurality. As a result, column ovens are not needed, and pre-heaters may not be required for each chromatography column in some exemplary embodiments. Thus, parallel column arrangements in the exemplary embodiments may be more compact than conventional arrangements.

公开(公告)号：US20210229119A1

公开(公告)日：2021-07-29

申请号：US17155462

申请日：2021-01-22

申请人： Waters Technologies Corporation

发明人： Wade P. Leveille ,  Joseph D. Michienzi ,  Jeffrey Musacchio ,  Emrys Jones ,  Steven Derek Pringle ,  Stephen Hattan ,  Gregory T. Roman

IPC分类号： B05B5/03 ,  B05B12/32

摘要： A sprayer assembly for an ion source is disclosed. The sprayer includes a capillary having an outlet, a sheath for the capillary, and an elastic member. The sheath can move relative to the capillary between a first position in which the sheath covers the outlet of the capillary and a second position in which the outlet of the capillary is exposed. When the sheath moves from the first position to or towards the second position, the elastic member provides a restoring force that acts to restore the position of the sheath to or towards the first position.

公开(公告)号：US10802002B2

公开(公告)日：2020-10-13

申请号：US15990097

申请日：2018-05-25

申请人： Waters Technologies Corporation

发明人： Joseph D. Michienzi ,  Keith Fadgen ,  Wade P. Leveille ,  Raymond P. Fisk ,  Frank John Marszalkowski, Jr.

IPC分类号： G01N30/60 ,  B01D15/10 ,  B01D15/22 ,  B05B5/16 ,  G01N30/72 ,  B01D15/18

摘要： Described is a chromatographic column assembly that includes an outer tube comprising a metal, a first conduit disposed within the outer tube, a second conduit disposed within the outer tube, and a first joint located between the first conduit and the second conduit. The outer tube is deformed by a first uniform radial crimp at a longitudinal location along the outer tube that surrounds the first conduit on a first side of the first joint, and a second uniform radial cramp at a longitudinal location along the outer tube that surrounds the second conduit on a second side of the first joint. The first and second uniform radial cramps form a fluid-tight seal between the first conduit and the second conduit and each have a substantially flat base region over which a diameter of the outer tube is reduced for a non-zero longitudinal length.

公开(公告)号：US20190187109A1

公开(公告)日：2019-06-20

申请号：US16223330

申请日：2018-12-18

申请人： Waters Technologies Corporation

发明人： Moon Chul Jung ,  Abhijit Tarafder ,  Wade P. Leveille

IPC分类号： G01N30/14 ,  B01D15/26 ,  B01D15/18

CPC分类号： G01N30/14 ,  B01D15/18 ,  B01D15/26 ,  G01N1/34 ,  G01N30/32 ,  G01N30/34 ,  G01N2030/143 ,  G01N2030/342

摘要： In various aspects provided are purification media and containers for dispensing a purified liquid are provided herein where a high surface area-to-volume chemically interactive purification media positioned at the outlet of a container that purifies the liquid as it is dispensed and/or extracted.

公开(公告)号：US20180202888A1

公开(公告)日：2018-07-19

申请号：US15872755

申请日：2018-01-16

申请人： Waters Technologies Corporation

发明人： Abhijit Tarafder ,  Moon Chul Jung ,  Jonathan L. Belanger ,  Xiangjin Song ,  Wade P. Leveille ,  Darryl W. Brousmiche

IPC分类号： G01M3/20 ,  G01N30/34 ,  G01N30/02

摘要： Systems, methods, and devices for detecting leaks in chromatography systems are disclosed. A coating is disposed to conform to at least one component of a chromatography system, such as a fitting or a section of tubing. The coating is made of or contains a responsive material that can undergo a detectable change when exposed to a chromatographic fluid or mobile phase. The change of the responsive material can indicate the presence of the fluid or mobile phase, a change in at least one physical property of the coating to prevent passage of the fluid or mobile phase, or a combination thereof.

公开(公告)号：US11428674B2

公开(公告)日：2022-08-30

申请号：US16415181

申请日：2019-05-17

申请人： Waters Technologies Corporation

发明人： Peter Kirby ,  Marcos O. Peroza ,  Steven D. Trudeau ,  Ryan Hill ,  Raymond P. Fisk ,  Jonathan Belanger ,  Wade P. Leveille

IPC分类号： G01N30/60 ,  B01D15/10 ,  G01N30/02 ,  F16L19/00 ,  G01N30/30

摘要： A clamp assembly includes a rail configured to receive a first fluidic assembly, and a carriage slidably mounted to the rail and configured to receive a second fluidic assembly. The carriage is operable to establish a first fluid tight seal between the first fluidic assembly and a chromatography column received within the claim assembly, and to establish a second fluid tight seal between the second fluidic assembly and the chromatography column.

公开(公告)号：US10953346B2

公开(公告)日：2021-03-23

申请号：US15873280

申请日：2018-01-17

申请人： Waters Technologies Corporation

发明人： Xiangjin Song ,  James P. Murphy ,  Keith Fadgen ,  Wade P. Leveille ,  Joseph D. Michienzi ,  Jonathan L. Belanger ,  Moon Chul Jung ,  Abhijit Tarafder

IPC分类号： B01D15/14 ,  B01L3/00 ,  B65D1/02 ,  B65D23/14 ,  G01N35/00 ,  G01N30/80 ,  B01L9/00 ,  G01N30/26

摘要： Solvent containers and solvent container trays for chromatography systems are described for providing control over solvent supply and waste collection. Designated solvent containers and exclusively designated solvent containers provide solvents for use by chromatography systems. Control over solvent supply is achieved by requiring matched container shape and container receiving position shape within the tray, and additionally or alternatively, through solvent container coding readable by the solvent tray and chromatography system which provide information about the solvent container to the chromatography system.

公开(公告)号：US10823713B2

公开(公告)日：2020-11-03

申请号：US15847586

申请日：2017-12-19

申请人： WATERS TECHNOLOGIES CORPORATION

发明人： Wade P. Leveille ,  Jonathan L. Belanger ,  Moon Chul Jung ,  Abhijit Tarafder ,  Joseph Michienzi ,  Keith Fadgen ,  Kevin Wyndham ,  Xiangjin Song

IPC分类号： G01N30/32 ,  B01D15/16 ,  B65D83/14 ,  G01N30/38

摘要： The present disclosure generally relates to systems, methods and devices for providing pressurized solvent flow in chromatography systems.

公开(公告)号：US10753916B2

公开(公告)日：2020-08-25

申请号：US15872842

申请日：2018-01-16

申请人： Waters Technologies Corporation

发明人： Moon Chul Jung ,  Jonathan L. Belanger ,  Xiangjin Song ,  Abhijit Tarafder ,  Joseph A. Jarrell ,  Wade P. Leveille

IPC分类号： G01N30/88 ,  G01M3/20 ,  G01N30/60 ,  G01N30/86 ,  G01M3/26 ,  G01N30/02 ,  G01N30/26 ,  G01N30/04

摘要： Systems, methods, and devices for detecting leaks in chromatography systems are disclosed. The leak detection system includes a sealable compartment disposed to surround at least one component of a chromatography system. The detector is in communication, e.g., fluid communication, with an interior of the sealable compartment and configured to detect the leak by various mean including the presence of liquid or the presence of vapor, or both within the sealable compartment.