利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

44 条记录 (耗时 0.029 秒)

    MAGE-C2 antigenic peptides and uses thereof
    1.
    发明授权
    MAGE-C2 antigenic peptides and uses thereof 失效
    MAGE-C2抗原肽及其用途

    公开(公告)号：US07547517B2

    公开(公告)日：2009-06-16

    申请号：US10670472

    申请日：2003-09-26

    申请人： Wenbin Ma ,  Benoit Van Den Eynde ,  Thierry Boon-Falleur ,  Catherine Germeau ,  Pierre Coulie

    发明人： Wenbin Ma ,  Benoit Van Den Eynde ,  Thierry Boon-Falleur ,  Catherine Germeau ,  Pierre Coulie

    IPC分类号： G01N33/53 ,  C07K17/00

    CPC分类号： C07K14/4748 ,  A61K38/00

    摘要： This invention relates to isolated peptides derived from MAGE-C2, nucleic acid molecules that encode MAGE-C2 and the isolated peptides derived from MAGE-C2, expression vectors comprising the nucleic acid molecules, host cells transformed or transfected with the nucleic acid molecules or the expression vectors, and to tetramers comprising the peptides, HLA molecules, β2 microglobulin and a first and second binding partner. This invention also relates to methods for using the peptides, nucleic acid molecules, expression vectors, tetramers and complexes of this invention as well as to cytolytic T cells which recognize the peptides in complex with an HLA molecule.

    摘要翻译： 本发明涉及衍生自MAGE-C2的分离的肽，编码MAGE-C2的核酸分子和来自MAGE-C2的分离的肽，包含核酸分子的表达载体，用核酸分子转化或转染的宿主细胞 表达载体和包含肽，HLA分子，β2微球蛋白和第一和第二结合配偶体的四聚体。 本发明还涉及使用本发明的肽，核酸分子，表达载体，四聚体和复合物以及识别与HLA分子复合的肽的细胞溶解性T细胞的方法。

    MAGE-C2 ANTIGENIC PEPTIDES AND USES THEREOF
    2.
    发明申请
    MAGE-C2 ANTIGENIC PEPTIDES AND USES THEREOF 有权
    MAGE-C2抗原肽及其用途

    公开(公告)号：US20110305722A1

    公开(公告)日：2011-12-15

    申请号：US13182037

    申请日：2011-07-13

    申请人： Wenbin MA ,  Benoit Van Den Eynde ,  Thierry Boon-Falleur ,  Catherine Germeau ,  Pierre Coulie

    发明人： Wenbin MA ,  Benoit Van Den Eynde ,  Thierry Boon-Falleur ,  Catherine Germeau ,  Pierre Coulie

    IPC分类号： A61K39/385 ,  A61P37/04 ,  C07K14/76 ,  A61P35/00 ,  C07K7/06 ,  G01N33/566

    CPC分类号： C07K14/4748 ,  A61K38/00

    摘要： This invention relates to isolated peptides derived from MAGE-C2, nucleic acid molecules that encode MAGE-C2 and the isolated peptides derived from MAGE-C2, expression vectors comprising the nucleic acid molecules, host cells transformed or transfected with the nucleic acid molecules or the expression vectors, and to tetramers comprising the peptides, HLA molecules, ∃2 microglobulin and a first and second binding partner. This invention also relates to methods for using the peptides, nucleic acid molecules, expression vectors, tetramers and complexes of this invention as well as to cytolytic T cells which recognize the peptides in complex with an HLA molecule.

    摘要翻译： 本发明涉及衍生自MAGE-C2的分离的肽，编码MAGE-C2的核酸分子和来自MAGE-C2的分离的肽，包含核酸分子的表达载体，用核酸分子转化或转染的宿主细胞 表达载体和包含肽，HLA分子，∃2微球蛋白和第一和第二结合配偶体的四聚体。 本发明还涉及使用本发明的肽，核酸分子，表达载体，四聚体和复合物以及识别与HLA分子复合的肽的细胞溶解性T细胞的方法。

    MAGE-C2 antigenic peptides and uses thereof
    3.
    发明授权
    MAGE-C2 antigenic peptides and uses thereof 有权
    MAGE-C2抗原肽及其用途

    公开(公告)号：US08143011B2

    公开(公告)日：2012-03-27

    申请号：US13182037

    申请日：2011-07-13

    申请人： Wenbin Ma ,  Benoit Van Den Eynde ,  Thierry Boon-Falleur ,  Catherine Germeau ,  Pierre Coulie ,  Nathalie Vigneron

    发明人： Wenbin Ma ,  Benoit Van Den Eynde ,  Thierry Boon-Falleur ,  Catherine Germeau ,  Pierre Coulie ,  Nathalie Vigneron

    IPC分类号： G01N33/53 ,  C07K17/00

    CPC分类号： C07K14/4748 ,  A61K38/00

    摘要： This invention relates to isolated peptides derived from MAGE-C2, nucleic acid molecules that encode MAGE-C2 and the isolated peptides derived from MAGE-C2, expression vectors comprising the nucleic acid molecules, host cells transformed or transfected with the nucleic acid molecules or the expression vectors, and to tetramers comprising the peptides, HLA molecules, ∃2 microglobulin and a first and second binding partner. This invention also relates to methods for using the peptides, nucleic acid molecules, expression vectors, tetramers and complexes of this invention as well as to cytolytic T cells which recognize the peptides in complex with an HLA molecule.

    摘要翻译： 本发明涉及衍生自MAGE-C2的分离的肽，编码MAGE-C2的核酸分子和来自MAGE-C2的分离的肽，包含核酸分子的表达载体，用核酸分子转化或转染的宿主细胞 表达载体和包含肽，HLA分子，∃2微球蛋白和第一和第二结合配偶体的四聚体。 本发明还涉及使用本发明的肽，核酸分子，表达载体，四聚体和复合物以及识别与HLA分子复合的肽的细胞溶解性T细胞的方法。

    MAGE-C2 antigenic peptides and uses therefor
    4.
    发明申请
    MAGE-C2 antigenic peptides and uses therefor 审中-公开
    MAGE-C2抗原肽及其用途

    公开(公告)号：US20090233315A1

    公开(公告)日：2009-09-17

    申请号：US12387884

    申请日：2009-05-08

    申请人： Wenbin Ma ,  Benoit Van Den Eynde ,  Thierry Boon-Falleur ,  Catherine Germeau ,  Pierre Coulie

    发明人： Wenbin Ma ,  Benoit Van Den Eynde ,  Thierry Boon-Falleur ,  Catherine Germeau ,  Pierre Coulie

    IPC分类号： G01N33/567 ,  C07K7/06

    CPC分类号： C07K14/4748 ,  A61K38/00

    摘要： This invention relates to isolated peptides derived from MAGE-C2, nucleic acid molecules that encode MAGE-C2 and the isolated peptides derived from MAGE-C2, expression vectors comprising the nucleic acid molecules, host cells transformed or transfected with the nucleic acid molecules or the expression vectors, and to tetramers comprising the peptides, HLA molecules, ∃2 microglobulin and a first and second binding partner. This invention also relates to methods for using the peptides, nucleic acid molecules, expression vectors, tetramers and complexes of this invention as well as to cytolytic T cells which recognize the peptides in complex with an HLA molecule.

    摘要翻译： 本发明涉及衍生自MAGE-C2的分离的肽，编码MAGE-C2的核酸分子和来自MAGE-C2的分离的肽，包含核酸分子的表达载体，用核酸分子转化或转染的宿主细胞 表达载体和包含肽，HLA分子，∃2微球蛋白和第一和第二结合配偶体的四聚体。 本发明还涉及使用本发明的肽，核酸分子，表达载体，四聚体和复合物以及识别与HLA分子复合的肽的细胞溶解性T细胞的方法。

    Endogenous retrovirus tumor associated nucleic acids and antigens
    5.
    发明授权
    Endogenous retrovirus tumor associated nucleic acids and antigens 失效
    内源性逆转录病毒肿瘤相关核酸和抗原

    公开(公告)号：US06770456B1

    公开(公告)日：2004-08-03

    申请号：US09124398

    申请日：1998-07-29

    申请人： Pierre Coulie ,  Thierry Boon-Falleur

    发明人： Pierre Coulie ,  Thierry Boon-Falleur

    IPC分类号： C12P2106

    CPC分类号： C07K14/4748 ,  A61K39/00 ,  G01N33/57484

    摘要： The invention describes HERV-AVL3-B tumor associated genes, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such genes, and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a HERV-AVL3-B gene product.

    摘要翻译： 本发明描述了HERV-AVL3-B肿瘤相关基因，包括其片段和生物功能变体。 还包括由这些基因编码的多肽及其片段，以及与之相关的抗体。 还提供了用于诊断和治疗以HERV-AVL3-B基因产物表达为特征的病症的方法和产品。