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1.发明申请公开(公告)号：US20130310442A1
公开(公告)日：2013-11-21
申请号：US13821669
申请日：2011-09-09
申请人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch , Nicole Dinse , Dirk Zboralski
发明人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch , Nicole Dinse , Dirk Zboralski
IPC分类号： A61K31/7105 , A61K31/69 , A61K35/12
CPC分类号： C12N15/115 , A61K31/69 , A61K31/7076 , A61K31/7088 , A61K31/7105 , A61K31/713 , A61K35/12 , A61K45/06 , C12N2310/16 , C12N2310/30 , C12N2310/351 , C12N2320/30 , C12N2320/31 , A61K2300/00
摘要： The present invention is related to a nucleic acid molecule capable of binding to SDF-1, preferably capable of inhibiting SDF-1, whereby the nucleic acid molecule is for use in a method for the treatment and/or prevention of a disease or disorder, for use in a method for the treatment of a subject suffering from a disease or disorder or being at risk of developing a disease or disorder as an adjunct therapy, or for use as a medicament for the treatment and/or prevention of a disease or disorder, whereby the disease or disorder is cancer.
摘要翻译： 本发明涉及能够结合SDF-1，优选能够抑制SDF-1的核酸分子，其中核酸分子用于治疗和/或预防疾病或病症的方法， 用于治疗患有疾病或障碍或患有作为辅助治疗的疾病或病症发生风险的受试者的方法，或用作治疗和/或预防疾病或病症的药物 ，其中疾病或病症是癌症。
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公开(公告)号：US08772257B2
公开(公告)日：2014-07-08
申请号：US12672449
申请日：2008-08-06
申请人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch , Nicole Dinse
发明人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch , Nicole Dinse
CPC分类号： C12N15/115 , A61K31/7105 , A61K31/713 , A61K47/60 , C07K14/521 , C07K16/24 , C12N2310/16 , C12N2310/351 , C12N2320/30 , Y02A50/401
摘要： The present invention is related to a nucleic acid molecule binding to SDF-1, whereby the nucleic acid molecule influences migration of cells.
摘要翻译： 本发明涉及与SDF-1结合的核酸分子，其中核酸分子影响细胞的迁移。
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公开(公告)号：US20110223127A1
公开(公告)日：2011-09-15
申请号：US12672449
申请日：2008-08-06
申请人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch , Nicole Dinse
发明人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch , Nicole Dinse
IPC分类号： A61K47/48 , C07H21/00 , C07H21/02 , C08G65/48 , A61K31/7088 , C12N5/071 , A61K35/12 , C12N5/078 , C12N5/0781 , C12N5/0783 , C07K16/24 , A61P9/00 , A61P35/02 , A61P7/06 , A61P35/00 , A61P35/04 , A61P37/04 , A61P19/02 , A61P29/00 , A61P3/10 , A61P17/06 , A61P17/00 , A61P9/10 , A61P25/00 , A61P37/06
CPC分类号： C12N15/115 , A61K31/7105 , A61K31/713 , A61K47/60 , C07K14/521 , C07K16/24 , C12N2310/16 , C12N2310/351 , C12N2320/30 , Y02A50/401
摘要： The present invention is related to a nucleic acid molecule binding to SDF-1, whereby the nucleic acid molecule influences migration of cells.
摘要翻译： 本发明涉及与SDF-1结合的核酸分子，其中核酸分子影响细胞的迁移。
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公开(公告)号：US08314223B2
公开(公告)日：2012-11-20
申请号：US12374311
申请日：2009-01-18
申请人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch , Nicole Dinse
发明人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch , Nicole Dinse
IPC分类号： C07H21/04
CPC分类号： C12N15/115 , C12N2310/16 , C12N2310/351 , C12N2320/30
摘要： The present invention is related to a nucleic acid molecule, preferably binding to SDF-1, selected from the group comprising type A nucleic acid molecules, type B nucleic acid molecules, type C nucleic acid molecules and nucleic acid molecules having a nucleic acid sequence according to any of SEQ ID NO:142, SEQ ID NO:143 or SEQ ID NO:144.
摘要翻译： 本发明涉及优选与SDF-1结合的核酸分子，所述核酸分子选自包含A型核酸分子，B型核酸分子，C型核酸分子和核酸分子的核酸分子，所述核酸分子具有根据 至SEQ ID NO：142，SEQ ID NO：143或SEQ ID NO：144中的任一个。
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公开(公告)号：US08507456B2
公开(公告)日：2013-08-13
申请号：US12679307
申请日：2008-09-24
申请人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
发明人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
CPC分类号： C12N15/115 , C12N2310/16 , C12N2310/3183 , C12N2310/323 , Y10T436/143333
摘要： The present invention is related to a nucleic acid, preferably binding to C5a, selected from the group comprising type A nucleic acids, type B nucleic acids, type C nucleic acids, type D nucleic acids and nucleic acids having a nucleic acid sequence according to any of SEQ.ID.No. 73 to 79.
摘要翻译： 本发明涉及优选结合C5a的核酸，其选自包含A型核酸，B型核酸，C型核酸，D型核酸和具有根据任何的核酸序列的核酸 SEQ.ID.No. 73到79。
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公开(公告)号：US20100284961A1
公开(公告)日：2010-11-11
申请号：US12279183
申请日：2007-02-14
申请人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
发明人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
IPC分类号： A61K38/19 , C07H21/02 , C07H21/00 , A61K31/7088 , A61K31/7105 , C40B30/00 , G01N33/53 , C40B40/00 , A61P37/02
CPC分类号： C12N15/1136 , C12N15/115 , C12N2310/16 , C12N2310/351 , C12Q1/6813 , G01N33/566
摘要： The present invention is related to a nucleic acid, preferably binding to MCP-1, selected from the group comprising type 1A nucleic acids, type 1B nucleic acids, type 2 nucleic acids, type 3 nucleic acids, type 4 nucleic acids and nucleic acids having a nucleic acid sequence according to any of SEQ. ID. No. 87 to 115.
摘要翻译： 本发明涉及优选结合MCP-1的核酸，其选自1A型核酸，1B型核酸，2型核酸，3型核酸，4型核酸和具有 根据SEQ ID NO：6中任一项所述的核酸序列。 ID。 第87至115号。
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公开(公告)号：US20150141496A1
公开(公告)日：2015-05-21
申请号：US14277826
申请日：2014-05-15
申请人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
发明人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
IPC分类号： C12N15/115 , A61K31/7088
CPC分类号： C12N15/115 , A61K31/7088 , C12N2310/16 , C12N2320/30
摘要： The present invention is related to a nucleic acid molecule capable of binding to MCP-I, whereby the nucleic acid molecule is for use as a medicament for the treatment and/or prevention of a chronic disease or chronic disorder, preferably selected from the group consisting of chronic respiratory disease, chronic kidney disease and systemic lupus erythematosus.
摘要翻译： 本发明涉及能够结合MCP-1的核酸分子，其中该核酸分子用作治疗和/或预防慢性疾病或慢性病症的药物，优选选自以下组 慢性呼吸系统疾病，慢性肾脏疾病和系统性红斑狼疮。
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公开(公告)号：US08193159B2
公开(公告)日：2012-06-05
申请号：US12279183
申请日：2007-02-14
申请人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
发明人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
CPC分类号： C12N15/1136 , C12N15/115 , C12N2310/16 , C12N2310/351 , C12Q1/6813 , G01N33/566
摘要： The present invention is related to a nucleic acid, preferably binding to MCP-1, selected from the group comprising type 1A nucleic acids, type 1B nucleic acids, type 2 nucleic acids, type 3 nucleic acids, type 4 nucleic acids and nucleic acids having a nucleic acid sequence according to any of SEQ. ID. No. 87 to 115.
摘要翻译： 本发明涉及优选结合MCP-1的核酸，其选自1A型核酸，1B型核酸，2型核酸，3型核酸，4型核酸和具有 根据SEQ ID NO：6中任一项所述的核酸序列。 ID。 第87至115号。
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公开(公告)号：US20130035376A1
公开(公告)日：2013-02-07
申请号：US13487341
申请日：2012-06-04
申请人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
发明人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
IPC分类号： C12N15/115 , A61K31/7088 , C40B30/04 , G01N33/566 , C12Q1/68
CPC分类号： C12N15/1136 , C12N15/115 , C12N2310/16 , C12N2310/351 , C12Q1/6813 , G01N33/566
摘要： The present invention is related to a nucleic acid, preferably binding to MCP-1, selected from the group consisting of Type 1A nucleic acids, type 1B nucleic acids, Type 2 nucleic acids, Type 3 nucleic acids, Type 4 nucleic acids and nucleic acids comprising SEQ ID NOs:87-115
摘要翻译： 本发明涉及优选结合MCP-1的核酸，其选自1A型核酸，1B型核酸，2型核酸，3型核酸，4型核酸和核酸 包含SEQ ID NO：87-115
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公开(公告)号：US20110046207A1
公开(公告)日：2011-02-24
申请号：US12679307
申请日：2008-09-24
申请人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
发明人： Werner Purschke , Florian Jarosch , Dirk Eulberg , Sven Klussmann , Klaus Buchner , Christian Maasch
IPC分类号： A61K31/7105 , C07H21/02 , G01N33/50 , C12Q1/68 , A61P27/02
CPC分类号： C12N15/115 , C12N2310/16 , C12N2310/3183 , C12N2310/323 , Y10T436/143333
摘要： The present invention is related to a nucleic acid, preferably binding to C5a, selected from the group comprising type A nucleic acids, type B nucleic acids, type C nucleic acids, type D nucleic acids and nucleic acids having a nucleic acid sequence according to any of SEQ.ID.No. 73 to 79.
摘要翻译： 本发明涉及优选结合C5a的核酸，其选自包含A型核酸，B型核酸，C型核酸，D型核酸和具有根据任何的核酸序列的核酸 SEQ.ID.No. 73到79。
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