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1.Substituted (2-oxo-1-benzimidazolinyl)-peperidines, process for their preparation, and use as anti-retroviral agents 失效
标题翻译: 取代的(2-氧代-1-苯并咪唑啉基) - 哌啶,其制备方法和用作抗逆转录病毒剂公开(公告)号:US5571921A
公开(公告)日:1996-11-05
申请号:US470372
申请日:1995-06-06
申请人: Wolfgang Bender , Dieter H abich , Siegfried Raddatz , Wolfgang R oben , Hanno Wild , Jutta Hansen , Arnold Paessens
发明人: Wolfgang Bender , Dieter H abich , Siegfried Raddatz , Wolfgang R oben , Hanno Wild , Jutta Hansen , Arnold Paessens
IPC分类号: A61K31/445 , A61K31/4427 , A61K31/495 , A61K31/505 , A61K31/535 , A61K31/675 , A61P31/12 , A61P31/18 , C07D401/04 , C07D401/14 , C07D417/14 , C07F9/6506
CPC分类号: C07D401/04 , C07D401/14 , C07D417/14
摘要: The present invention relates to substituted (2-oxo-1-benzimidazolinyl)-piperidines of the general formula (I) ##STR1## in which the substituents have the meaning indicated in the description, to processes for their preparation and to their use as antiretroviral agents.
摘要翻译: 本发明涉及通式(I)的取代的(2-氧代-1-苯并咪唑啉基) - 哌啶,其中取代基具有说明书中指出的含义,其制备方法及其制备方法 用作抗逆转录病毒药物。
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2.Use of substituted chromans, some of which are known, as medicaments, new active compounds and processes for their preparation 失效
标题翻译: 取代的苯并二氢吡喃酮(其中一些已知的)用作药物,新的活性化合物及其制备方法公开(公告)号:US5492918A
公开(公告)日:1996-02-20
申请号:US251986
申请日:1994-06-01
申请人: Hanno Wild , Wolfgang Bender , Dieter Habich , Hans-Georg Heine , Siegfried Raddatz , Wolfgang Roben , Jutta Hansen , Arnold Paessens
发明人: Hanno Wild , Wolfgang Bender , Dieter Habich , Hans-Georg Heine , Siegfried Raddatz , Wolfgang Roben , Jutta Hansen , Arnold Paessens
IPC分类号: A61K31/443 , A61K31/445 , A61P31/12 , C07D405/06 , C07D405/14
CPC分类号: C07D405/06 , C07D405/14
摘要: The present invention relates to the use of substituted chromans of the general formula (I) ##STR1## in which the substituents have the meaning indicated in the description, for the production of medicaments, in particular as HIV protease-inhibiting agents, new active compounds and processes for their preparation.
摘要翻译: 本发明涉及通式(I)的取代苯并二氢吡喃的用途,其中取代基具有说明书中指出的含义,用于生产药物,特别是作为HIV蛋白酶抑制剂,新的活性化合物 及其制备方法。
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公开(公告)号:US5457108A
公开(公告)日:1995-10-10
申请号:US122279
申请日:1993-09-17
申请人: Hanno Wild , Jutta Hansen , Jorg Lautz , Arnold Paessens
发明人: Hanno Wild , Jutta Hansen , Jorg Lautz , Arnold Paessens
IPC分类号: A61K31/13 , A61K31/27 , A61K31/40 , A61K31/403 , A61K31/404 , A61K31/47 , A61K31/535 , A61K31/5375 , A61K31/66 , A61K31/675 , A61P31/12 , A61P31/18 , C07C233/33 , C07C271/20 , C07C271/52 , C07C311/06 , C07C317/28 , C07C317/44 , C07D209/18 , C07D209/42 , C07D215/48 , C07D295/13 , C07D295/20 , C07D493/08 , C07F7/18 , C07F9/40 , C07D215/38 , C07D209/14 , C07D213/04
CPC分类号: C07D295/13 , C07C271/20 , C07C317/44 , C07D209/42 , C07D215/48 , C07F7/1852 , C07F9/4006 , C07F9/4056 , C07C2103/32
摘要: The invention relates to substituted 5-oxo-di-benzo[a,d]cyclohepta-1,4-dienes of the formula (I) ##STR1## processes for their preparation and their use as retroviral agents.
摘要翻译: 本发明涉及式(I)的取代的5-氧代 - 二苯并[a,d]环庚烷-1,4-二烯,其制备方法及其作为逆转录病毒剂的用途。
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公开(公告)号:US5627181A
公开(公告)日:1997-05-06
申请号:US503369
申请日:1995-07-17
申请人: Bernd Riedl , Dieter H abich , Andreas Stolle , Hanno Wild , Rainer Endermann , Klaus D. Bremm , Hein-Peter Kroll , Harald Labischinski , Klaus Schaller , Hans-Otto Werling
发明人: Bernd Riedl , Dieter H abich , Andreas Stolle , Hanno Wild , Rainer Endermann , Klaus D. Bremm , Hein-Peter Kroll , Harald Labischinski , Klaus Schaller , Hans-Otto Werling
IPC分类号: C07D237/20 , A61K31/44 , A61K31/4418 , A61K31/47 , A61K31/495 , A61K31/50 , A61P31/04 , C07D213/72 , C07D215/38 , C07D215/48 , C07D239/42 , C07D241/44 , C07D413/04 , C07D413/14 , C07D417/14 , C07D471/04 , A61K31/535
CPC分类号: C07D413/04 , C07D413/14 , C07D417/14
摘要: The invention relates to 6-membered nitrogen-containing heteroaryloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
摘要翻译: 本发明涉及6元含氮杂芳基恶唑烷酮,其制备方法及其作为药物的用途,特别是抗菌药物。
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5.6-thiono-5,6-dihydro-dibenz[B,E] azepin-11-one-11-oximes 失效
标题翻译: 6-硫基-5,6-二氢 - 二苯并[B,E]吖庚因-11-酮-11-肟公开(公告)号:US5545736A
公开(公告)日:1996-08-13
申请号:US370000
申请日:1995-01-09
IPC分类号: A61K31/55 , A61K31/00 , A61P31/12 , A61P43/00 , C07D223/20 , C07D405/12 , C12N9/99 , A61F31/55
CPC分类号: C07D223/20
摘要: The invention relates to 6-thiono-dibenz[b,e]azepines, to a process for their preparation and to their use as inhibitors of reverse transcriptase and in particular as antiretroviral agents.
摘要翻译: 本发明涉及6-硫杂 - 二苯并[b,e]吖庚因,其制备方法及其作为逆转录酶抑制剂,特别是作为抗逆转录病毒剂的用途。
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公开(公告)号:US5416209A
公开(公告)日:1995-05-16
申请号:US978001
申请日:1992-11-18
IPC分类号: A61K31/00 , A61K31/55 , A61P31/12 , A61P43/00 , C07D223/20 , C07D405/12 , C12N9/99
CPC分类号: C07D405/12 , C07D223/20
摘要: The invention relates to 5,6-dihydro-dibenz[b,e]azepine-6,11-dione-11-oximes, to processes for their preparation and to their use as inhibitors of reverse transcriptase and in particular as antiretroviral agents.
摘要翻译: 本发明涉及5,6-二氢 - 二苯并[b,e]吖庚因-6,11-二酮-11-肟,用于其制备及其作为逆转录酶抑制剂,特别是抗逆转录病毒剂的用途。
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7.Aminoalkyl-substituted 5,6-dihydro-dibenz[b,e]azepine-6,11-dione-11-oximes 失效
标题翻译: 氨基烷基取代的5,6-二氢 - 二苯并[b,e]吖庚因-6,11-二酮-11-肟公开(公告)号:US5385899A
公开(公告)日:1995-01-31
申请号:US977379
申请日:1992-11-17
IPC分类号: A61K31/00 , A61K31/55 , A61P31/12 , A61P43/00 , C07D223/20 , C07D413/12 , C12N9/99 , C07D223/16
CPC分类号: C07D223/20
摘要: The invention relates to aminoalkyl-substituted 5,6-dihydro-dibenz[b,e]azepine-6,11-dione-11-oximes, to processes for their preparation and to their use as antiretroviral agents.
摘要翻译: 本发明涉及氨基烷基取代的5,6-二氢 - 二苯并[b,e]吖庚因-6,11-二酮-11-肟,用于其制备及其作为抗逆转录病毒剂的用途。
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8.4-(pyridin-3-yl)-2(pyridin-2yl)-1,2-dihydro-3H-pyrazol-3-one derivatives as specific HIF-pyrolyl-4-hydroxylase inhibitors for treating cardiovascular and haematological diseases 有权
标题翻译: 4-(吡啶-3-基)-2(吡啶-2-基)-1,2-二氢-3H-吡唑-3-酮衍生物作为特异性HIF-裂解-4-羟化酶抑制剂用于治疗心血管和血液病公开(公告)号:US09085572B2
公开(公告)日:2015-07-21
申请号:US13594622
申请日:2012-08-24
申请人: Ingo Flamme , Jens-Kerim Ergüden , Felix Oehme , Kai Thede , Gunter Karig , Alexander Kuhl , Hanno Wild , Joachim Schuhmacher , Peter Kolkhof , Lars Bärfacker , Joachim Hütter
发明人: Ingo Flamme , Jens-Kerim Ergüden , Felix Oehme , Kai Thede , Gunter Karig , Alexander Kuhl , Hanno Wild , Joachim Schuhmacher , Peter Kolkhof , Lars Bärfacker , Joachim Hütter
IPC分类号: C07D401/14 , A61K31/4439 , C07D413/14
CPC分类号: C07D413/14 , C07D401/14
摘要: The present application relates to novel dipyridyl-dihydropyrazolones, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.
摘要翻译: 本申请涉及新的联吡啶基 - 二氢吡唑酮,其制备方法,其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是心血管和血液疾病和肾脏的药物的用途 疾病和促进伤口愈合。
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公开(公告)号:US06187799B1
公开(公告)日:2001-02-13
申请号:US09083399
申请日:1998-05-22
申请人: Jill E Wood , Hanno Wild , Daniel H Rogers , John Lyons , Michael Katz , Yolanda Caringal , Robert Dally , Wendy Lee , Roger A. Smith , Cheri Blum
发明人: Jill E Wood , Hanno Wild , Daniel H Rogers , John Lyons , Michael Katz , Yolanda Caringal , Robert Dally , Wendy Lee , Roger A. Smith , Cheri Blum
IPC分类号: A61K3138
CPC分类号: C07D207/34 , C07D307/68 , C07D333/38 , C07D409/12 , C07D417/12 , C07D471/04
摘要: Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.
摘要翻译: 治疗由raf激酶介导的肿瘤与取代的脲化合物及其化合物本身的方法。
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公开(公告)号:US5843967A
公开(公告)日:1998-12-01
申请号:US749581
申请日:1996-11-15
申请人: Bernd Riedl , Dieter Habich , Andreas Stolle , Hanno Wild , Rainer Endermann , Klaus Dieter Bremm , Hein-Peter Kroll , Harald Labischinski , Klaus Schaller , Hans-Otto Werling
发明人: Bernd Riedl , Dieter Habich , Andreas Stolle , Hanno Wild , Rainer Endermann , Klaus Dieter Bremm , Hein-Peter Kroll , Harald Labischinski , Klaus Schaller , Hans-Otto Werling
IPC分类号: C07D237/20 , A61K31/44 , A61K31/4418 , A61K31/47 , A61K31/495 , A61K31/50 , A61P31/04 , C07D213/72 , C07D215/38 , C07D215/48 , C07D239/42 , C07D241/44 , C07D413/04 , C07D413/14 , C07D417/14 , C07D471/04 , C07D401/04
CPC分类号: C07D413/04 , C07D413/14 , C07D417/14
摘要: The invention relates to 6-membered nitrogen-containing heteroaryloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
摘要翻译: 本发明涉及6元含氮杂芳基恶唑烷酮,其制备方法及其作为药物的用途,特别是抗菌药物。
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