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公开(公告)号：US20170152371A1
公开(公告)日：2017-06-01
申请号：US14953472
申请日：2015-11-30
申请人： Ping Duan , Anil K. Sadana , Suman Khatiwada , Yingqing Xu , Xiao Wang
发明人： Ping Duan , Anil K. Sadana , Suman Khatiwada , Yingqing Xu , Xiao Wang
CPC分类号： C08K7/14 , B29C43/003 , B29K2105/0002 , B29K2105/0067 , B29K2995/006 , C08K3/16 , E21B33/00 , E21B33/1208 , E21B34/00 , E21B41/00
摘要： A degradable polymer composition comprises a polyurethane comprising ester groups in a backbone of the polyurethane and carboxylic acid groups attached to the backbone of the polyurethane; and a filler comprising one or more of the following: a powder comprising particles having an average particle size of about 5 microns to about 500 microns; or a fiber having an average length of about ⅛ inch to about 5 inches. Also disclosed are articles comprising the composition. A method to degrade the article includes exposing the article to a fluid at a temperature of about 25° C. to about 300° C.
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公开(公告)号：US10329407B2
公开(公告)日：2019-06-25
申请号：US14953472
申请日：2015-11-30
申请人： Ping Duan , Anil K. Sadana , Suman Khatiwada , Yingqing Xu , Xiao Wang
发明人： Ping Duan , Anil K. Sadana , Suman Khatiwada , Yingqing Xu , Xiao Wang
IPC分类号： C08K7/14 , B29C43/00 , E21B41/00 , C08K3/16 , E21B33/00 , E21B33/12 , E21B34/00 , B29K105/00
摘要： A degradable polymer composition comprises a polyurethane comprising ester groups in a backbone of the polyurethane and carboxylic acid groups attached to the backbone of the polyurethane; and a filler comprising one or more of the following: a powder comprising particles having an average particle size of about 5 microns to about 500 microns; or a fiber having an average length of about ⅛ inch to about 5 inches. Also disclosed are articles comprising the composition. A method to degrade the article includes exposing the article to a fluid at a temperature of about 25° C. to about 300° C.
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公开(公告)号：US10227471B2
公开(公告)日：2019-03-12
申请号：US15211661
申请日：2016-07-15
申请人： Xiao Wang , Ping Duan , Anil K. Sadana
发明人： Xiao Wang , Ping Duan , Anil K. Sadana
摘要： A degradable polymer composite comprises a polyurethane comprising one or more of the following groups: ester groups; carbonate groups; or ether groups, in a backbone of the polyurethane; and about 1 to about 30 parts by weight of an acidic or basic powder comprising particles having an average size of about 5 microns to about 1 millimeter per 100 parts of the polyurethane.
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公开(公告)号：US20180016411A1
公开(公告)日：2018-01-18
申请号：US15211661
申请日：2016-07-15
申请人： Xiao Wang , Ping Duan , Anil K. Sadana
发明人： Xiao Wang , Ping Duan , Anil K. Sadana
CPC分类号： C08K3/30 , C08G18/10 , C08G18/42 , C08G18/44 , C08G18/48 , C08G18/7621 , C08G2230/00 , C08K2201/005 , E21B33/12 , E21B34/06 , C08G18/3243
摘要： A degradable polymer composite comprises a polyurethane comprising one or more of the following groups: ester groups; carbonate groups; or ether groups, in a backbone of the polyurethane; and about 1 to about 30 parts by weight of an acidic or basic powder comprising particles having an average size of about 5 microns to about 1 millimeter per 100 parts of the polyurethane.
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公开(公告)号：US20150210825A1
公开(公告)日：2015-07-30
申请号：US14209057
申请日：2014-03-13
申请人： Anil K. Sadana , Xiao Wang , James R. Korte
发明人： Anil K. Sadana , Xiao Wang , James R. Korte
IPC分类号： C08K3/34
CPC分类号： C08F2/44 , C08K9/04 , C08K9/12 , C08K2201/011 , C08F220/56 , C08F220/06 , C08F2220/585
摘要： Nanocomposite microgel particles containing a three-dimensional network, containing a water-swellable nanoclay and an organic network polymer. The nanocomposite microgel particles include primary nanocomposite microgel particles having a mean diameter of 1 to 10 micrometers. Also disclosed is a method of manufacture for the nanocomposite microgel particles. The nanocomposite microgel particles can be used together with a base polymer to provide water swellable compositions.
摘要翻译： 含有三维网络的纳米复合微凝胶颗粒，含有水溶胀性纳米粘土和有机网状聚合物。 纳米复合微凝胶颗粒包括平均直径为1至10微米的初级纳米复合微粒凝胶颗粒。 还公开了纳米复合微凝胶颗粒的制造方法。 纳米复合微凝胶颗粒可以与基础聚合物一起使用以提供水溶胀性组合物。
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6.发明授权Methods of manufacturing poly(hexahydrotriazine)s via suspension or emulsion polymerization 有权通过悬浮或乳液聚合制备聚（六氢三嗪）的方法公开(公告)号：US09505885B2
公开(公告)日：2016-11-29
申请号：US14674213
申请日：2015-03-31
申请人： Xiao Wang , Anil K. Sadana , Suman Khatiwada
发明人： Xiao Wang , Anil K. Sadana , Suman Khatiwada
CPC分类号： C08G73/065 , C08G12/08 , C08G73/024 , C08G73/0638 , C08G73/0644 , C08J3/12 , C08J2379/04
摘要： A method of manufacturing a hemiaminal dynamic covalent network (HDCN) comprises reacting a diamine and formaldehyde in the presence of a reaction medium comprising a polar solvent and a nonpolar solvent at a temperature of about 15° C. to about 100° C. to form the HDCN. A composition comprising the produced HDCN can be molded to form various articles comprising poly(hexahydrotriazine)s.
摘要翻译： 制备血液动力共价网络（HDCN）的方法包括在约15℃至约100℃的温度下，在包含极性溶剂和非极性溶剂的反应介质存在下使二胺和甲醛反应形成 HDCN。 可以将包含所生产的HDCN的组合物模制成包含聚（六氢三嗪）的各种制品。
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公开(公告)号：US20150210824A1
公开(公告)日：2015-07-30
申请号：US14163553
申请日：2014-01-24
申请人： Xiao Wang , Anil K. Sadana
发明人： Xiao Wang , Anil K. Sadana
IPC分类号： C08K3/34
CPC分类号： C08K3/346 , C08F2/44 , C08K2201/011 , Y10T428/2982
摘要： Nanocomposite microgel particles containing a three-dimensional network, containing a water-swellable nanoclay and an organic network polymer. The nanocomposite microgel particles include primary nanocomposite microgel particles having a mean diameter of 1 to 10 micrometers. Also disclosed is a method of manufacture for the nanocomposite microgel particles.
摘要翻译： 含有三维网络的纳米复合微凝胶颗粒，含有水溶胀性纳米粘土和有机网状聚合物。 纳米复合微凝胶颗粒包括平均直径为1至10微米的初级纳米复合微粒凝胶颗粒。 还公开了纳米复合微凝胶颗粒的制造方法。
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8.发明申请METHODS OF MANUFACTURING POLY(HEXAHYDROTRIAZINE)S VIA SUSPENSION OR EMULSION POLYMERIZATION 有权通过悬浮或乳液聚合制备聚（十六氢化INE INE INE INE））ATION ATION ATION ATION ATION ATION ATION ATION ATION ATION ATION ATION公开(公告)号：US20160289387A1
公开(公告)日：2016-10-06
申请号：US14674213
申请日：2015-03-31
申请人： Xiao Wang , Anil K. Sadana , Suman Khatiwada
发明人： Xiao Wang , Anil K. Sadana , Suman Khatiwada
CPC分类号： C08G73/065 , C08G12/08 , C08G73/024 , C08G73/0638 , C08G73/0644 , C08J3/12 , C08J2379/04
摘要： A method of manufacturing a hemiaminal dynamic covalent network (HDCN) comprises reacting a diamine and formaldehyde in the presence of a reaction medium comprising a polar solvent and a nonpolar solvent at a temperature of about 15° C. to about 100° C. to form the HDCN. A composition comprising the produced HDCN can be molded to form various articles comprising poly(hexahydrotriazine)s.
摘要翻译： 制备血液动力共价网络（HDCN）的方法包括在约15℃至约100℃的温度下，在包含极性溶剂和非极性溶剂的反应介质存在下使二胺和甲醛反应形成 HDCN。 可以将包含所生产的HDCN的组合物模制成包含聚（六氢三嗪）的各种制品。
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公开(公告)号：US09334337B2
公开(公告)日：2016-05-10
申请号：US14209057
申请日：2014-03-13
申请人： Anil K. Sadana , Xiao Wang , James R. Korte
发明人： Anil K. Sadana , Xiao Wang , James R. Korte
IPC分类号： C08K9/04 , C08K9/12 , C08F2/44 , C08F220/56
CPC分类号： C08F2/44 , C08K9/04 , C08K9/12 , C08K2201/011 , C08F220/56 , C08F220/06 , C08F2220/585
摘要： Nanocomposite microgel particles containing a three-dimensional network, containing a water-swellable nanoclay and an organic network polymer. The nanocomposite microgel particles include primary nanocomposite microgel particles having a mean diameter of 1 to 10 micrometers. Also disclosed is a method of manufacture for the nanocomposite microgel particles. The nanocomposite microgel particles can be used together with a base polymer to provide water swellable compositions.
摘要翻译： 含有三维网络的纳米复合微凝胶颗粒，含有水溶胀性纳米粘土和有机网状聚合物。 纳米复合微凝胶颗粒包括平均直径为1至10微米的初级纳米复合微粒凝胶颗粒。 还公开了纳米复合微凝胶颗粒的制造方法。 纳米复合微凝胶颗粒可以与基础聚合物一起使用以提供水溶胀性组合物。
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公开(公告)号：US20210389303A1
公开(公告)日：2021-12-16
申请号：US17347360
申请日：2021-06-14
IPC分类号： G01N33/50 , C07K14/435 , C12N15/11 , C12N9/22 , C12N15/90
摘要： Provided herein are compositions and methods for real-time identification and isolation of base-edited cell populations. Also provided herein are methods for producing enriched isogenic lines of genetically modified cells, including base-edited human pluripotent stem cells. In particular, provided herein are methods utilizing transient expression of reporter proteins, the detectable signal of which is altered following base editing. Using the transient reporter with a base editor permits enrichment of isogenic populations of base-edited cells.
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