公开(公告)号：US20140067082A1

公开(公告)日：2014-03-06

申请号：US13832455

申请日：2013-03-15

申请人： Xinyin Liu ,  Mark Fulmer ,  Peter Schaut ,  Kevin Joye

发明人： Xinyin Liu ,  Mark Fulmer ,  Peter Schaut ,  Kevin Joye

IPC分类号： A61L27/56 ,  A61L27/10

CPC分类号： A61L24/0042 ,  A61L24/001 ,  A61L24/02 ,  A61L27/10 ,  A61L27/12 ,  A61L27/32 ,  A61L27/50 ,  A61L27/56 ,  A61L27/58 ,  A61L2400/06 ,  A61L2420/02 ,  A61L2420/08 ,  A61L2430/02 ,  B05D1/12 ,  B05D3/007 ,  C04B28/14 ,  C04B28/344 ,  C04B2111/00836

摘要： The present disclosure is directed to a bioresorbable ceramic composition having a plurality of biocompatible ceramic granules, each of the granules having a coating of a plurality of calcium containing particles, where at least a portion of the particles are bound to at least a portion of an outer surface of each of the granules, and further where the composition is flowable in a dry state. The present disclosure is also directed to a three dimensional scaffold for bone repair that includes the bioresorbable composition, which upon implantation to a locus of repair defines an interconnected pore network between outer walls of the coated granules of the composition. Finally, the present disclosure is directed to methods of forming both the bioresorbable ceramic composition and the three-dimensional ceramic scaffold.

摘要翻译： 本公开涉及具有多个生物相容性陶瓷颗粒的生物可吸收陶瓷组合物，每个颗粒具有多个含钙颗粒的涂层，其中至少一部分颗粒与至少一部分 每个颗粒的外表面，并且其中组合物在干燥状态下可流动。 本公开还涉及用于骨修复的三维支架，其包括生物可再吸收组合物，其在植入修复位点时限定组合物的包衣颗粒的外壁之间的互连孔网络。 最后，本公开涉及形成生物可吸收陶瓷组合物和三维陶瓷支架的方法。