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公开(公告)号：US08649860B2
公开(公告)日：2014-02-11
申请号：US12781459
申请日：2010-05-17
IPC分类号： A61N1/39
CPC分类号： A61N1/37252 , A61B5/02 , A61B5/04 , A61B5/0452 , A61B5/6846 , A61N1/025 , A61N1/3621 , A61N1/3702 , A61N1/372 , A61N1/3925
摘要： Monitoring physiological parameter using an implantable physiological monitor in order to detect a condition predictive of a possible future pathological episode and collecting additional physiological data associated with the condition predictive of a possible future pathological episode. Monitoring another physiological parameter in order to detect a condition indicative of the beginning of a present pathological episode and collecting additional pathological data in response to the condition. Determining that the condition predictive of a future episode and the condition indicative of a present episode are associated and, in response thereto, storing all the collected physiological data.
摘要翻译： 使用植入式生理监测器监测生理参数，以便检测预测可能的未来病理发作的状况并收集与预测可能的未来病理发作相关的条件相关的附加生理数据。 监测另一个生理参数，以便检测指示本病理发作开始的病症，并根据病情收集额外的病理资料。 确定预测未来事件的状况和指示当前情节的状况是相关联的，并且响应于此，存储所有收集的生理数据。
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公开(公告)号：US20100305642A1
公开(公告)日：2010-12-02
申请号：US12781459
申请日：2010-05-17
IPC分类号： A61N1/00
CPC分类号： A61N1/37252 , A61B5/02 , A61B5/04 , A61B5/0452 , A61B5/6846 , A61N1/025 , A61N1/3621 , A61N1/3702 , A61N1/372 , A61N1/3925
摘要： Monitoring physiological parameter using an implantable physiological monitor in order to detect a condition predictive of a possible future pathological episode and collecting additional physiological data associated with the condition predictive of a possible future pathological episode. Monitoring another physiological parameter in order to detect a condition indicative of the beginning of a present pathological episode and collecting additional pathological data in response to the condition. Determining that the condition predictive of a future episode and the condition indicative of a present episode are associated and, in response thereto, storing all the collected physiological data.
摘要翻译： 使用植入式生理监测器监测生理参数，以便检测预测可能的未来病理发作的状况并收集与预测可能的未来病理发作相关的条件相关的附加生理数据。 监测另一个生理参数，以便检测指示本病理发作开始的病症，并根据病情收集额外的病理资料。 确定预测未来事件的状况和指示当前情节的状况是相关联的，并且响应于此，存储所有收集的生理数据。
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公开(公告)号：US07110816B2
公开(公告)日：2006-09-19
申请号：US10878953
申请日：2004-06-28
IPC分类号： A61N1/365
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.
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4.发明授权Reduction of left-ventricular offset interaction with tachyarrhythmia detection 有权减慢与心律失常检测的左心室偏移相互作用公开(公告)号：US06757562B2
公开(公告)日：2004-06-29
申请号：US10037444
申请日：2001-10-25
IPC分类号： A61N1362
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.
摘要翻译： 通过向两个心室分配指定的偏移间隔来逐步重新同步心室，从而改善快速性心律失常检测的装置和方法。 逃避间隔和快速性心律失常检测的时间是基于指定为速率心室的心室之一的感觉。 提供回波起搏模式，以便当速率心室在另一脑室之后起搏时，防止快速性心律失常检测受到损害。
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5.发明授权Reduction of left-ventricular offset interaction with tachyarrhythmia detection 有权减慢与心律失常检测的左心室偏移相互作用公开(公告)号：US07801609B2
公开(公告)日：2010-09-21
申请号：US11522691
申请日：2006-09-18
IPC分类号： A61N1/00
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.
摘要翻译： 通过向两个心室分配指定的偏移间隔来逐步重新同步心室，从而改善快速性心律失常检测的装置和方法。 逃避间隔和快速性心律失常检测的时间是基于指定为速率心室的心室之一的感觉。 提供回波起搏模式，以便当速率心室在另一脑室之后起搏时，防止快速性心律失常检测受到损害。
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6.发明授权公开(公告)号：US09814395B2
公开(公告)日：2017-11-14
申请号：US13568887
申请日：2012-08-07
申请人： Jeffrey E. Stahmann , David J. Ternes , Barun Maskara , Shantha Arcot-Krishnamurthy , Juan Gabriel Hincapie Ordonez , Scott Vanderlinde
发明人： Jeffrey E. Stahmann , David J. Ternes , Barun Maskara , Shantha Arcot-Krishnamurthy , Juan Gabriel Hincapie Ordonez , Scott Vanderlinde
IPC分类号： A61B5/02 , A61B5/00 , A61B5/021 , A61B5/0215 , A61B5/0295 , A61B5/053 , A61B5/107
CPC分类号： A61B5/02007 , A61B5/021 , A61B5/0215 , A61B5/0295 , A61B5/0535 , A61B5/1076 , A61B5/4836 , A61B5/686 , A61B5/6876 , A61B5/6877 , A61B5/7203 , A61B5/7275
摘要： Implanted electrodes can be used to deliver electrical stimulation signals to areas near blood vessels, nerves, or other internal body locations. In an example, an electrode can be implanted in a cervical location and can be used to measure dimensional changes in an artery using impedance plethysmography. Measured artery dimensional changes can be used to determine one or more physiological parameters associated with a patient's health status, such as pulse transit time, relative pulse pressure, or aterial compliance, among others. These parameters can be used to monitor a patient health status or to modulate a patient's therapy, among other uses. In some examples, an electrode configured to deliver an electrostimulation signal to nerve tissue can be used to provide non-neurostimulating electrical stimulation plethysmography signals near a blood vessel.
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公开(公告)号：US09375566B2
公开(公告)日：2016-06-28
申请号：US13185203
申请日：2011-07-18
IPC分类号： A61N1/08
CPC分类号： A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/053 , A61B5/0816 , A61B5/0826 , A61B5/091 , A61B5/1116 , A61B5/1118 , A61B5/4878 , A61B5/686 , A61B5/746 , A61B7/02 , A61N1/08
摘要： An embodiment of a device for reporting a heart failure status of a patient comprises: a parameter acquisition module configured to acquire at least one trended heart failure parameter; a predetermined event acquisition module configured to acquire at least one predetermined event corresponding to the at least one trended heart failure parameter, wherein each of the at least one predetermined event represents an event condition where a predetermined event definition is satisfied; an alert acquisition module configured to acquire at least one heart failure status alert associated with the at least one predetermined event, wherein each of the at least one alert represents an alert condition where a predetermined alert definition is satisfied; and an output communication module configured to communicate the at least one heart failure status alert.
摘要翻译： 用于报告患者的心力衰竭状态的装置的实施例包括：参数获取模块，被配置为获取至少一个趋势性心力衰竭参数; 预定事件获取模块，被配置为获取与所述至少一个趋势性心力衰竭参数相对应的至少一个预定事件，其中所述至少一个预定事件中的每一个表示满足预定事件定义的事件条件; 警报采集模块，被配置为获取与所述至少一个预定事件相关联的至少一个心力衰竭状态警报，其中所述至少一个警报中的每一个表示满足预定警报定义的警报状况; 以及输出通信模块，被配置为通信所述至少一个心力衰竭状态警报。
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8.发明授权Sensitivity and specificity of pulmonary edema detection when using transthoracic impedance 有权使用经胸阻塞时肺水肿检测的灵敏度和特异性公开(公告)号：US09089275B2
公开(公告)日：2015-07-28
申请号：US11126723
申请日：2005-05-11
IPC分类号： A61B5/053
CPC分类号： A61B5/053 , A61B5/0537 , A61B5/4869 , A61M2230/40 , A61M2230/65 , A61N1/36521 , A61N1/37282
摘要： This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.
摘要翻译： 该专利文献尤其涉及用于增强肺水肿检测的系统，装置和方法，除胸部阻抗之外，还包括以下之一或组合：关于受试者的生理信息，至少一个统计参数， 可编程检测水平，与先前的肺水肿事件相关联的至少一个参数，以及关于受试者的患者症状信息。 在一个示例中，（基底）胸部阻抗阈值被修改为经调整的胸部阻抗阈值。 与基础胸廓阻抗阈值相比，经调整的胸廓阻抗阈值提供了肺水肿检测的灵敏度增加。 在另一示例中，基于由本系统，设备和方法确定的肺水肿指示，向受检者，照顾者或其他用户提供警报。 在另一个实例中，响应于肺水肿指示调整或启动治疗（提供给受试者）。
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公开(公告)号：US08938296B2
公开(公告)日：2015-01-20
申请号：US12214855
申请日：2008-06-23
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A device and method for cardiac rhythm management in which a heart chamber is paced in accordance with sense signals from the opposite chamber or other distant cardiac site. The method is particularly useful in delivering cardiac resynchronization therapy.
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10.发明授权System and method for determining pulmonary performance from transthoracic impedance measures 有权用于确定经胸阻抗措施的肺功能的系统和方法公开(公告)号：US08795189B2
公开(公告)日：2014-08-05
申请号：US12029422
申请日：2008-02-11
申请人： Quan Ni , Jesse W. Hartley , Kent Lee , Jeffrey E. Stahmann
发明人： Quan Ni , Jesse W. Hartley , Kent Lee , Jeffrey E. Stahmann
IPC分类号： A61B5/08
CPC分类号： A61B5/0809 , A61B5/0002 , A61B5/0535 , A61N1/36521 , G06F19/3418
摘要： A system and method for determining pulmonary performance from transthoracic impedance measures is provided. Transthoracic impedance measures collected by an implantable medical device are correlated to pulmonary functional measures. The pulmonary functional measures are grouped by respiratory pattern. Pulmonary performance is evaluated. Differences are determined by comparing the pulmonary functional measures for each respiratory pattern to the pulmonary functional measures for at least one previous respiratory pattern. A trend is identified from the differences. An alert is generated upon sufficient deviation of the trend from a threshold criteria.
摘要翻译： 提供了一种通过经胸阻抗测量来确定肺功能的系统和方法。 由可植入医疗器械收集的经胸阻抗测量与肺功能测量相关。 肺功能测量按呼吸模式分组。 评估肺功能。 通过将每个呼吸模式的肺功能测量与至少一个之前的呼吸模式的肺功能测量进行比较来确定差异。 从差异中确定出一个趋势。 在趋势与阈值标准的充分偏差之后产生警报。
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