利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

13 条记录 (耗时 0.038 秒)

    Screening method
    1.
    发明授权
    Screening method 失效
    筛选方法

    公开(公告)号：US07892755B2

    公开(公告)日：2011-02-22

    申请号：US11661555

    申请日：2005-08-29

    申请人： Yasuaki Ito ,  Kazunori Nishi ,  Shoichi Ohkubo ,  Masataka Harada

    发明人： Yasuaki Ito ,  Kazunori Nishi ,  Shoichi Ohkubo ,  Masataka Harada

    IPC分类号： G01N33/566 ,  A61K38/00

    CPC分类号： G01N33/6893 ,  C07K14/705 ,  G01N33/574 ,  G01N2500/00

    摘要： The present invention provides a method of screening a compound or its salt that alters binding properties of a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1, or a salt thereof, and a ligand capable of specifically binding to the protein or its salt, which comprises using (a) the protein, its partial peptide, or a salt thereof and (b) the ligand; a screening kit therefor, and so on. The screening method and kit of the present invention are useful for screening an agent for the prevention/treatment of, e.g., digestive tract disorders, cancer, immune disorders, type II diabetes mellitus or obesity, etc.

    摘要翻译： 本发明提供一种筛选化合物或其盐的方法，其改变包含与SEQ ID NO：1所示的氨基酸序列相同或基本上相同的氨基酸序列的蛋白质的结合性，或其盐，和 能够特异性结合蛋白质或其盐的配体，其包括使用（a）蛋白质，其部分肽或其盐和（b）配体; 一个筛选工具，等等。 本发明的筛选方法和试剂盒可用于筛选用于预防/治疗例如消化道疾病，癌症，免疫疾病，II型糖尿病或肥胖症等的药剂。

    Screening Method
    2.
    发明申请
    Screening Method 失效
    筛选方法

    公开(公告)号：US20080103215A1

    公开(公告)日：2008-05-01

    申请号：US11661555

    申请日：2005-08-29

    申请人： Yasuaki Ito ,  Kazunori Nishi ,  Shoichi Ohkubo ,  Masataka Harada

    发明人： Yasuaki Ito ,  Kazunori Nishi ,  Shoichi Ohkubo ,  Masataka Harada

    IPC分类号： A61K45/00 ,  G01N33/53 ,  G01N33/15 ,  A61P1/00 ,  A61P3/10 ,  A61P35/00 ,  A61P37/00 ,  A61P3/04

    CPC分类号： G01N33/6893 ,  C07K14/705 ,  G01N33/574 ,  G01N2500/00

    摘要： The present invention provides a method of screening a compound or its salt that alters binding properties of a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1, or a salt thereof, and a ligand capable of specifically binding to the protein or its salt, which comprises using (a) the protein, its partial peptide, or a salt thereof and (b) the ligand; a screening kit therefor, and so on. The screening method and kit of the present invention are useful for screening an agent for the prevention/treatment of, e.g., digestive tract disorders, cancer, immune disorders, type II diabetes mellitus or obesity, etc.

    摘要翻译： 本发明提供一种筛选化合物或其盐的方法，其改变包含与SEQ ID NO：1所示的氨基酸序列相同或基本上相同的氨基酸序列的蛋白质的结合性，或其盐，和 能够特异性结合蛋白质或其盐的配体，其包括使用（a）蛋白质，其部分肽或其盐和（b）配体; 一个筛选工具，等等。 本发明的筛选方法和试剂盒可用于筛选用于预防/治疗例如消化道疾病，癌症，免疫疾病，II型糖尿病或肥胖症等的药剂。

    Projection exposure apparatus and method of correcting projection error
    10.
    发明授权
    Projection exposure apparatus and method of correcting projection error 失效
    投影曝光装置和校正投影误差的方法

    公开(公告)号：US4958160A

    公开(公告)日：1990-09-18

    申请号：US238196

    申请日：1988-08-30

    申请人： Yasuaki Ito ,  Takehiko Suzuki ,  Hirokazu Shimeki

    发明人： Yasuaki Ito ,  Takehiko Suzuki ,  Hirokazu Shimeki

    IPC分类号： G03F7/20

    CPC分类号： G03F7/70691 ,  G03F7/70358

    摘要： A projection exposure apparatus in which a wafer is illuminated with a light of slit-like shape from a mask and a carriage for supporting the mask and the wafer as a unit is moved in a predetermined direction relative to a projection optical system, including a mirror system, wherein a pattern formed on the mask is printed on the wafer, is disclosed. By adjusting the attitude of the carriage during movement, a projection error of the pattern of the mask, being projected on the wafer, is corrected. Data necessary for adjusting the carriage attitude is obtained by photoelectrically detecting alignment marks of the mask and the wafer. As a feature, a setting device is provided to allow the setting of the number of wafers, of those of a predetermined number, which are to be treated as the subject of data detection. This makes the apparatus to easily meet either of the requirements of higher precision and higher throughput, as desired. Also, the amount of actual change in the attitude of the carriage, with respect to the instruction value based on the data, is preparatorily detected before the pattern printing and is memorized. This assures higher precision correction of the projection error.

    摘要翻译： 投影曝光装置，其中以掩模和狭缝状的光照射晶片作为一个单元的投影光学系统相对于包括镜子的投影光学系统在预定的方向上移动 系统，其中形成在掩模上的图案被印刷在晶片上。 通过在移动期间调整滑架的姿态，校正投影在晶片上的掩模图案的投影误差。 通过光电检测掩模和晶片的对准标记来获得调整滑架姿态所需的数据。 作为特征，提供了一种设置装置，以允许设置要被视为数据检测对象的预定数量的晶片数量。 这使得装置能够根据需要容易地满足更高精度和更高产量的要求。 此外，在图案打印之前，预先检测出基于数据的托架姿态的实际变化量，并且被记忆。 这样可以更精确地校正投影误差。