公开(公告)号：US20050107868A1

公开(公告)日：2005-05-19

申请号：US10950620

申请日：2004-09-28

申请人： Yasuhide Nakayama ,  Eisuke Tatsumi ,  Yasushi Nemoto

发明人： Yasuhide Nakayama ,  Eisuke Tatsumi ,  Yasushi Nemoto

IPC分类号： A61L27/38 ,  A61L27/50 ,  A61L27/56 ,  A61F2/06 ,  A61F2/02

CPC分类号： A61L27/38 ,  A61L27/507 ,  A61L27/56

摘要： The invention provides a porous scaffold for tissue engineering which allows easy cell engraftment and cell culture and thus enables stable organization and an artificial blood vessel which exhibits high patency rate even if the inner diameter is small. The scaffold for tissue engineering is made of thermoplastic resin which forms a porous three-dimensional network structure having communication property, wherein the porous three-dimensional network structure has an average pore diameter of from 100 to 650 μm and an apparent density of from 0.01 to 0.5 g/cm3. The artificial blood vessel is composed of this scaffold. The invention provides a cuff which allows easy infiltration of cells from living subcutaneous tissues, easy engraftment of cells, and neovascularization of capillary vessels so as to obtain robust bonding with subcutaneous tissues and, as a result, ensures separation of a wounded portion from the outside, thereby blocking exacerbation factors such as bacterial infection on healing and inhibiting progression of downgrowth. That is, the invention provides a cuff with none or little infection trouble such as tunnel infection. The cuff comprises a porous three-dimensional network structure which is made of thermoplastic resin or thermosetting resin and has communication property, wherein the porous three-dimensional network structure has an average pore diameter of from 100 to 1000 μm and apparent density of from 0.01 to 0.5 g/cm3. The invention provides a biological implant covering member which allows easy infiltration of cells from living subcutaneous tissues, easy engraftment of cells, and organization, thereby obtaining robust bonding with native tissues and therefore protecting a living body from adverse effect which may occur due to the insertion of a biological implantation member into the living body. The biological implant covering member comprises a porous three-dimensional network structure which is made of thermoplastic resin or thermosetting resin and has communication property, wherein the porous three-dimensional network structure has an average pore diameter of from 100 to 1000 μm and apparent density of from 0.01 to 0.5 g/cm3.

公开(公告)号：US20060036311A1

公开(公告)日：2006-02-16

申请号：US10525016

申请日：2003-08-20

申请人： Yasuhide Nakayama ,  Shogo Nishi ,  Yasushi Nemoto ,  Yoshihiro Okamoto

发明人： Yasuhide Nakayama ,  Shogo Nishi ,  Yasushi Nemoto ,  Yoshihiro Okamoto

IPC分类号： A61F2/90 ,  A61F2/82

CPC分类号： A61F2/90 ,  A61F2002/072 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2250/0067 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/00 ,  B29C41/042 ,  B29C41/14 ,  B29C41/20 ,  B29C41/22 ,  B29K2995/0059 ,  B29K2995/006 ,  B29L2031/753

摘要： A stent comprising a tubular stent matrix of which diameter is extendable and a flexible polymer layer covering the stent matrix. The polymer layer is closely attached to and covers the entire surface of the stent matrix. Since the flexible polymer layer closely covers the entire surface of the stent matrix not only the outer periphery of the stent matrix, the stent has no problem of causing allergic to metal, stimulus of tissues due to metal, and rust development. Since the inner periphery of the stent is a flat and smooth surface covered by the polymer layer without convexes and concaves, the formation of thrombus can be inhibited well. There is no problem of drift between the polymer layer and the stent matrix, thereby maintaining the positional relationship between the stent matrix and the polymer layer before and after the expansion of the stent.

摘要翻译： 一种支架，其包括直径可延伸的管状支架基质和覆盖支架基质的柔性聚合物层。 聚合物层紧密地附着并覆盖支架基质的整个表面。 由于柔性聚合物层不仅覆盖支架基体的整个表面，而且不仅支架基体的外周，所以支架不会引起金属过敏，金属刺激，以及生锈。 由于支架的内周是由没有凸起和凹陷的聚合物层覆盖的平坦且光滑的表面，因此可以良好地抑制血栓的形成。 在聚合物层和支架基体之间不存在漂移问题，从而在支架膨胀前后维持支架基体与聚合物层之间的位置关系。

公开(公告)号：US08591782B2

公开(公告)日：2013-11-26

申请号：US10525016

申请日：2003-08-20

申请人： Yasuhide Nakayama ,  Shogo Nishi ,  Yasushi Nemoto ,  Yoshihiro Okamoto

发明人： Yasuhide Nakayama ,  Shogo Nishi ,  Yasushi Nemoto ,  Yoshihiro Okamoto

IPC分类号： B29C37/02

CPC分类号： A61F2/90 ,  A61F2002/072 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2250/0067 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/00 ,  B29C41/042 ,  B29C41/14 ,  B29C41/20 ,  B29C41/22 ,  B29K2995/0059 ,  B29K2995/006 ,  B29L2031/753

摘要： A stent comprising a tubular stent matrix of which diameter is extendable and a flexible polymer layer covering the stent matrix. The polymer layer is closely attached to and covers the entire surface of the stent matrix. Since the flexible polymer layer closely covers the entire surface of the stent matrix not only the outer periphery of the stent matrix, the stent has no problem of causing allergic to metal, stimulus of tissues due to metal, and rust development. Since the inner periphery of the stent is a flat and smooth surface covered by the polymer layer without convexes and concaves, the formation of thrombus can be inhibited well. There is no problem of drift between the polymer layer and the stent matrix, thereby maintaining the positional relationship between the stent matrix and the polymer layer before and after the expansion of the stent.

摘要翻译： 一种支架，其包括直径可延伸的管状支架基质和覆盖支架基质的柔性聚合物层。 聚合物层紧密地附着并覆盖支架基质的整个表面。 由于柔性聚合物层不仅覆盖支架基体的整个表面，而且不仅支架基体的外周，所以支架不会引起金属过敏，金属刺激，以及生锈。 由于支架的内周是由没有凸起和凹陷的聚合物层覆盖的平坦且光滑的表面，因此可以良好地抑制血栓的形成。 在聚合物层和支架基体之间不存在漂移问题，从而在支架膨胀前后维持支架基体与聚合物层之间的位置关系。

公开(公告)号：US20160329548A1

公开(公告)日：2016-11-10

申请号：US15096500

申请日：2016-04-12

申请人： Aya Harada ,  Eiji Hojo ,  Yasuhide Nakayama ,  Shin Osaki ,  Hiroshi Okumura ,  Katsuya Noguchi

发明人： Aya Harada ,  Eiji Hojo ,  Yasuhide Nakayama ,  Shin Osaki ,  Hiroshi Okumura ,  Katsuya Noguchi

IPC分类号： H01M2/30 ,  H01M2/02

CPC分类号： H01M2/305 ,  H01M2/0242 ,  H01M2/30 ,  H01M2220/20 ,  H01R43/00 ,  Y10T29/49208

摘要： A storage battery includes a terminal portion for storage batteries having a plurality of bolt insertion holes bored in one or a plurality of directions, a nut insertion opening through which a nut is inserted, a hollow in communication with the bolt insertion holes and the nut insertion opening and the nut having at least one screw hole threaded in a direction coincident with at least one or the plurality of directions. A fixation portion is formed to fix the nut by deforming the terminal portion with the nut being inserted through the nut insertion opening into the hollow and the at least one screw hole of the nut being in communication respectively with the at least one of the plurality of bolt insertion holes.

摘要翻译： 蓄电池包括：具有多个在一个或多个方向上钻孔的螺栓插入孔的蓄电池的端子部分，插入有螺母的螺母插入口，与螺栓插入孔连通的中空部， 所述螺母具有沿与至少一个或多个方向一致的方向螺纹的至少一​​个螺纹孔。 固定部分形成为通过使螺母插入通过螺母插入口进入中空部的螺母使端子部分变形来固定螺母，并且螺母的至少一个螺纹孔分别与多个 螺栓插孔。

公开(公告)号：US08298817B2

公开(公告)日：2012-10-30

申请号：US11252063

申请日：2005-10-18

申请人： Yasuhide Nakayama ,  Makoto Nagaishi ,  Mariko Shiba

发明人： Yasuhide Nakayama ,  Makoto Nagaishi ,  Mariko Shiba

IPC分类号： C12N15/00 ,  A61K47/48 ,  C08G63/48 ,  C08G63/91

CPC分类号： A61K48/0041 ,  A61K31/7088

摘要： The present invention provides a vector which can make nucleic acids to be an aggregate and locate a vector containing a cationic polymer to surround the aggregate so as to protect the nucleic acids from the enzyme. The vector comprises a polymer having branched chain(s). Preferably, 3, 4, or 6 branched chains are bonded to benzene ring. It is preferable that the number of the branched chains is higher. As the branched chain(s), a vinyl-series acrylic polymer is preferable. The vector is synthesized by reacting a dithiocarbamate compound with an acrylamide monomer for the branched chain(s).

摘要翻译： 本发明提供了一种载体，其能够使核酸成为聚集体并且定位包含阳离子聚合物的载体以包围聚集体，以便保护核酸免于酶。 载体包含具有支链的聚合物。 优选地，3,4或6个支链键合到苯环上。 支链的数目较好。 作为支链，优选乙烯基系丙烯酸类聚合物。 载体通过二硫代氨基甲酸酯化合物与支链的丙烯酰胺单体反应而合成。

公开(公告)号：US5225298A

公开(公告)日：1993-07-06

申请号：US564280

申请日：1990-08-08

申请人： Yasuhide Nakayama ,  Katsumi Kitagawa ,  Kenjiro Kishimoto ,  Junji Muto ,  Hironori Kitawaki ,  Shoji Sugiyama

发明人： Yasuhide Nakayama ,  Katsumi Kitagawa ,  Kenjiro Kishimoto ,  Junji Muto ,  Hironori Kitawaki ,  Shoji Sugiyama

IPC分类号： H01M2/16

CPC分类号： H01M2/1613 ,  H01M2300/0005

摘要： A separator in which a flowing rate of an electrolyte is less than 100 mm/hr and a sealed lead acid battery using the separator.

摘要翻译： 电解液的流动速度小于100mm /小时的分离器和使用隔膜的密封型铅酸电池。

公开(公告)号：US5206100A

公开(公告)日：1993-04-27

申请号：US731148

申请日：1991-07-15

申请人： Junji Muto ,  Hironori Kitawaki ,  Shoji Sugiyama ,  Yasuhide Nakayama ,  Katsumi Kitagawa ,  Kenjiro Kishimoto

发明人： Junji Muto ,  Hironori Kitawaki ,  Shoji Sugiyama ,  Yasuhide Nakayama ,  Katsumi Kitagawa ,  Kenjiro Kishimoto

IPC分类号： H01M2/16

CPC分类号： H01M2/1613 ,  H01M2300/0005

摘要： A separator substantially comprising only alkali-containing glass fibers with an average fiber diameter of less than 2 .mu.m, and having an electrolyte dripping speed of lower than 80 mm/hr and a content of sulfer S at the surface of the glass fibers of less than 0.02% by weight, as well as a sealed lead acid battery using such a separator.

摘要翻译： 基本上仅含有平均纤维直径小于2μm的含碱玻璃纤维，并且电解液滴落速度低于80mm / hr，玻璃纤维表面的硫化物S含量较少的隔板 超过0.02重量％，以及使用这种隔膜的密封铅酸电池。

公开(公告)号：US20140212765A1

公开(公告)日：2014-07-31

申请号：US14349180

申请日：2012-09-07

申请人： Aya Harada ,  Yasuhide Nakayama

发明人： Aya Harada ,  Yasuhide Nakayama

IPC分类号： H01M10/12

CPC分类号： H01M10/121 ,  H01M2/1613 ,  H01M4/14 ,  H01M4/56 ,  H01M2004/021

摘要： A valve-regulated lead acid battery comprises an element including a positive electrode plate which retains a positive active material, a negative electrode plate which retains a negative active material, and a separator. An average pore diameter of the negative active material measured by a bubble point method is 0.2 μm or more and 0.35 μm or less. An average pore diameter of the separator measured by the bubble point method is 10 to 40 times as large as the average pore diameter of the negative active material.

摘要翻译： 阀调节铅酸电池包括一个元件，它包括一个保持正极活性材料的正极板，一个负极活性材料的负极板和一个隔板。 通过泡点法测定的负极活性物质的平均孔径为0.2μm以上且0.35μm以下。 通过泡点法测定的隔膜的平均孔径为负极活性物质的平均孔径的10〜40倍。

公开(公告)号：US08652669B2

公开(公告)日：2014-02-18

申请号：US13057886

申请日：2009-08-04

申请人： Yasuhide Nakayama ,  Eiji Hojo ,  Masashi Shiota ,  Shin Ohsaki ,  Shinichi Egami

发明人： Yasuhide Nakayama ,  Eiji Hojo ,  Masashi Shiota ,  Shin Ohsaki ,  Shinichi Egami

IPC分类号： H01M2/12

CPC分类号： H01M2/1252 ,  H01M2/1217

摘要： A lead-acid battery comprising a container having at least one cell chamber and a lid body for covering a top opening of the container. The lid body has on a top surface a recessed portion having therein an annular portion protruding upward and having, in an area of a bottom wall inside the protruding portion, an exhaust hole for exhausting gas from the cell chamber, wherein a guide passage for guiding gas from the exhaust hole to the outside is formed by joining the protruding portion with a joining portion provided on the lid body cover. An annular groove formed between the protruding portion and the vertical wall is covered with an outer periphery of the lid body cover 5 and the guide passage is isolated from the groove.

摘要翻译： 一种铅酸电池，包括具有至少一个电池室的容器和用于覆盖容器顶部开口的盖体。 所述盖体在顶面上具有凹部，所述凹部具有向上突出的环状部，在所述突出部内部的底壁区域具有用于从所述电池室排出气体的排气孔，其特征在于， 通过将突出部与设置在盖体盖上的接合部接合而形成从排气孔到外部的气体。 形成在突出部和垂直壁之间的环形槽被盖体盖5的外周覆盖，并且引导通道与槽隔离。

公开(公告)号：US20130183558A1

公开(公告)日：2013-07-18

申请号：US13825400

申请日：2011-12-12

申请人： Yasuhide Nakayama ,  Eiji Hojo ,  Katsuhiro Ouchi ,  Hidehiko Shibata

发明人： Yasuhide Nakayama ,  Eiji Hojo ,  Katsuhiro Ouchi ,  Hidehiko Shibata

IPC分类号： H01M2/12

CPC分类号： H01M2/1252 ,  H01M2/043 ,  H01M2/1094 ,  H01M2/12 ,  H01M2/1247 ,  H01M10/12 ,  H01M2220/20 ,  Y02E60/126

摘要： A vehicular lead storage battery according to the present invention includes a battery container provided with at least one cell chamber; and a cover plate 1 for covering an upper opening of the battery container. A guide path 8 for discharging gases within a cell chamber to the outside is formed in the cover plate 1. The guide path 8 includes a first guide portion 9B for horizontally guiding gases from the cell chamber; a second guide portion 9C connected to the first guide portion 9B to downwardly guide the gases from the first guide portion 9B; and a third guide portion 10A connected to the second guide portion 9C to horizontally guide the gases from the second guide portion 9C and discharge the gases from an exhaust vent 4K formed in the cover plate 1 to the outside. A corner portion 9K is formed by the first guide portion 9B and the second guide portion 9C, and a corner portion 10K is formed by the second guide portion 9C and the third guide portion 10A. The guide path 8 is formed so that the angle θ of a straight line L having internal contact with the two corner portions 9K and 10K from a horizontal line is greater than the maximum angle of inclination at which the inclined angle of a vehicle is maximum during driving on a sloping ground.

摘要翻译： 根据本发明的车载铅蓄电池包括设置有至少一个电池室的电池容器; 以及用于覆盖电池容器的上部开口的盖板1。 在盖板1中形成用于将细胞室内的气体排出到外部的引导路径8.引导路径8包括用于水平地引导来自细胞室的气体的第一引导部分9B; 连接到第一引导部9B的第二引导部9C，以向下引导来自第一引导部9B的气体; 以及连接到第二引导部分9C的水平地引导来自第二引导部分9C的气体并将形成在盖板1中的排气口4K的气体排出到外部的第三引导部分10A。 角部9K由第一引导部9B和第二引导部9C形成，角部10K由第二引导部9C和第三引导部10A形成。 引导路径8形成为使得从水平线与两个角部9K和10K内部接触的直线L的角度θ大于车辆的倾斜角度的最大倾斜角度 在斜坡上行驶。