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    Scaffold for tissue engineering, artificial blood vessel, cuff, and biological implant covering member
    1.
    发明申请
    Scaffold for tissue engineering, artificial blood vessel, cuff, and biological implant covering member 审中-公开

    公开(公告)号：US20050107868A1

    公开(公告)日：2005-05-19

    申请号：US10950620

    申请日：2004-09-28

    申请人： Yasuhide Nakayama ,  Eisuke Tatsumi ,  Yasushi Nemoto

    发明人： Yasuhide Nakayama ,  Eisuke Tatsumi ,  Yasushi Nemoto

    IPC分类号： A61L27/38 ,  A61L27/50 ,  A61L27/56 ,  A61F2/06 ,  A61F2/02

    CPC分类号： A61L27/38 ,  A61L27/507 ,  A61L27/56

    摘要： The invention provides a porous scaffold for tissue engineering which allows easy cell engraftment and cell culture and thus enables stable organization and an artificial blood vessel which exhibits high patency rate even if the inner diameter is small. The scaffold for tissue engineering is made of thermoplastic resin which forms a porous three-dimensional network structure having communication property, wherein the porous three-dimensional network structure has an average pore diameter of from 100 to 650 μm and an apparent density of from 0.01 to 0.5 g/cm3. The artificial blood vessel is composed of this scaffold. The invention provides a cuff which allows easy infiltration of cells from living subcutaneous tissues, easy engraftment of cells, and neovascularization of capillary vessels so as to obtain robust bonding with subcutaneous tissues and, as a result, ensures separation of a wounded portion from the outside, thereby blocking exacerbation factors such as bacterial infection on healing and inhibiting progression of downgrowth. That is, the invention provides a cuff with none or little infection trouble such as tunnel infection. The cuff comprises a porous three-dimensional network structure which is made of thermoplastic resin or thermosetting resin and has communication property, wherein the porous three-dimensional network structure has an average pore diameter of from 100 to 1000 μm and apparent density of from 0.01 to 0.5 g/cm3. The invention provides a biological implant covering member which allows easy infiltration of cells from living subcutaneous tissues, easy engraftment of cells, and organization, thereby obtaining robust bonding with native tissues and therefore protecting a living body from adverse effect which may occur due to the insertion of a biological implantation member into the living body. The biological implant covering member comprises a porous three-dimensional network structure which is made of thermoplastic resin or thermosetting resin and has communication property, wherein the porous three-dimensional network structure has an average pore diameter of from 100 to 1000 μm and apparent density of from 0.01 to 0.5 g/cm3.

    Cuff member
    2.
    发明申请
    Cuff member 审中-公开
    袖口会员

    公开(公告)号：US20070198053A1

    公开(公告)日：2007-08-23

    申请号：US11506815

    申请日：2006-08-21

    申请人： Eisuke Tatsumi ,  Toshihide Mizuno ,  Yoshiyuki Taenaka ,  Yasushi Nemoto ,  Yoshihiro Okamoto ,  Hare Tazawa

    发明人： Eisuke Tatsumi ,  Toshihide Mizuno ,  Yoshiyuki Taenaka ,  Yasushi Nemoto ,  Yoshihiro Okamoto ,  Hare Tazawa

    IPC分类号： A61B17/00

    CPC分类号： A61M25/02 ,  A61L31/146 ,  A61M2025/0266 ,  A61M2025/0293

    摘要： A cuff member that enhances the invasion and engraftment of cells from subcutaneous tissue of a living body and robustly adheres to the subcutaneous tissue through the vascularization of capillary vessels, and can consequently isolate a wound from the outside, block exacerbating factors such as bacterial infection during healing, inhibit the downgrowth, and reduce infection problems including tunnel infection. A cuff member 2 includes a flange 3 and a tubular portion 4. The cuff member 2 includes a three-dimensional network open-cell porous structure, which is formed of a thermoplastic resin or a thermosetting resin and has an average pore size of 100 to 1000 μm and an apparent density of 0.01 to 0.5 g/cm3. A pad 5 overlies the flange 3. A tube 6 passes through the pad 5 and the flange 3.

    摘要翻译： 一种增强从生物体皮下组织侵入和移植细胞的囊袋，通过毛细血管的血管化牢固地粘附在皮下组织上，从而将伤口从外部分离出来，阻止诸如细菌感染的加重因素 愈合，抑制下丘，减少感染问题，包括隧道感染。 套箍构件2包括凸缘3和管状部分4。 袖带构件2包括由热塑性树脂或热固性树脂形成的平均孔径为100〜1000μm，表观密度为0.01〜0.5g / cm 3的三维网状开孔多孔结构体， SUP> 3 。 垫5叠在凸缘3上。 管6穿过垫5和凸缘3。