公开(公告)号：US07135566B2

公开(公告)日：2006-11-14

申请号：US10481246

申请日：2002-06-19

申请人： Yasuhiro Kajihara ,  Ken Sasaki

发明人： Yasuhiro Kajihara ,  Ken Sasaki

IPC分类号： C07H1/06 ,  C07H5/06

CPC分类号： C07H13/10 ,  C07H5/06 ,  C07H7/027 ,  C07H15/12 ,  C12P13/04 ,  C12P19/04 ,  C12P19/28 ,  Y02P20/55

摘要： The present invention provides a process for preparing a sugar chain asparagine derivative. According to the process, various isolated sugar chain asparagine derivatives useful in the field of the development of pharmaceuticals and the like can be conveniently obtained in a large amount as compared to that of the prior art. The present invention also provides a process for preparing a sugar chain asparagine and a process for preparing a sugar chain via a step for preparing a sugar chain asparagine derivative. The present invention further provides a novel sugar chain asparagine derivative, a sugar chain asparagine and a sugar chain.

摘要翻译： 本发明提供了制备糖链天冬酰胺衍生物的方法。 根据该方法，与现有技术相比，可以方便地获得与药物开发领域有用的各种分离的糖链天冬酰胺衍生物。 本发明还提供了制备糖链天冬酰胺的方法和通过制备糖链天冬酰胺衍生物的步骤制备糖链的方法。 本发明还提供了一种新型的糖链天冬酰胺衍生物，糖链天冬酰胺和糖链。

公开(公告)号：US09030589B2

公开(公告)日：2015-05-12

申请号：US14127818

申请日：2012-08-07

申请人： Ken Sasaki ,  Nobuhiro Takeda

发明人： Ken Sasaki ,  Nobuhiro Takeda

IPC分类号： H04N3/14 ,  H04N5/335 ,  H04N5/232 ,  H04N5/359 ,  H04N5/355 ,  H04N5/3745 ,  H01L27/146

CPC分类号： H04N5/359 ,  H01L27/14621 ,  H01L27/14627 ,  H01L27/14641 ,  H04N5/355 ,  H04N5/3559 ,  H04N5/3745

摘要： An image sensor comprises a plurality of pixels, and each pixel having: a plurality of photoelectric conversion units configured to receive light fluxes that pass through different exit pupil regions of an optical system disposed on an object side of the image sensor and accumulate charges, respectively; a separation portion configured to separate the photoelectric conversion units; and setting means configured to selectively set an electric potential of the separation portion to any one of a plurality of electric potentials. Signals can be separately read out from the photoelectric conversion units. Taking an electric potential of a separation portion that separates the plurality of pixels as a reference potential, the plurality of electric potentials include first to third electric potentials; higher than the reference potential, lower than the reference potential, and higher than the reference potential and lower than the first electric potential.

摘要翻译： 图像传感器包括多个像素，并且每个像素具有：多个光电转换单元，被配置为接收通过分别设置在图像传感器的物体侧的光学系统的不同出射光瞳区域的光束并分别积累电荷 ; 分离部，被配置为分离所述光电转换单元; 以及设定装置，被配置为选择性地将分离部分的电位设置为多个电位中的任一个。 信号可以从光电转换单元分别读出。 将多个像素分离为基准电位的分离部分的电位，所述多个电位包括第一至第三电位; 高于参考电位，低于参考电位，并高于参考电位并低于第一电位。

公开(公告)号：US20110092424A1

公开(公告)日：2011-04-21

申请号：US12895517

申请日：2010-09-30

申请人： Ken Sasaki ,  Vanessa Jane Williamson ,  Alberto de Araujo ,  Ewa Walczyk

发明人： Ken Sasaki ,  Vanessa Jane Williamson ,  Alberto de Araujo ,  Ewa Walczyk

IPC分类号： A61K38/00 ,  C07K14/00 ,  C12P21/06 ,  C07H21/04

CPC分类号： C07K14/605 ,  C07K2319/00

摘要： GLP-2 peptides and analogs thereof are produced in high yield and with desired, authentic termini by isolation from a GLP-2 peptide multimer in which at least two units of GLP-2 peptide are coupled through a linker that presents an N-terminal acid cleavage site and a C-terminal enzyme cleavage site. In a specific embodiment, [Gly2]hGLP-2 is produced from a multimeric precursor comprising 2-30 units thereof.

摘要翻译： 通过从其中至少两个单元的GLP-2肽通过呈现N末端酸的连接体偶联的GLP-2肽多聚体分离，以高产率和期望的真实末端产生GLP-2肽及其类似物 切割位点和C末端酶切割位点。 在一个具体实施方案中，[Gly2] hGLP-2由包含其2-30单位的多聚体前体产生。

公开(公告)号：US20110011550A1

公开(公告)日：2011-01-20

申请号：US12921485

申请日：2009-03-25

申请人： Takaharu Noda ,  Masato Ogimoto ,  Katsumasa Ono ,  Ken Sasaki ,  Takeshi Takahashi

发明人： Takaharu Noda ,  Masato Ogimoto ,  Katsumasa Ono ,  Ken Sasaki ,  Takeshi Takahashi

IPC分类号： D21F11/00

CPC分类号： D21H27/002 ,  D21H11/16

摘要： The present invention aims to provide soft and pleasant-to-touch tissue papers for household use with high strength.Provided are a tissue paper for household use characterized in that it contains a pulp obtained by applying an impact force produced during the collapse of bubbles generated by cavitation to pulp fibers and a tissue paper for household use consisting of two or more paper layers characterized in that at least one paper layer contains a pulp obtained by applying an impact force produced during the collapse of bubbles generated by cavitation to pulp fibers.

摘要翻译： 本发明的目的在于提供具有高强度家用的柔软易感的薄纸。 本发明提供一种家用薄页纸，其特征在于，其含有通过将由气蚀产生的气泡崩解产生的冲击力施加到纸浆纤维而获得的纸浆和由两层或多层纸层构成的家用纸巾，其特征在于， 至少一层纸层含有通过将由气蚀产生的气泡崩解产生的冲击力施加到纸浆纤维而获得的纸浆。

公开(公告)号：US20060159709A1

公开(公告)日：2006-07-20

申请号：US11013711

申请日：2004-12-16

申请人： Sheena Loosmore ,  Ken Sasaki ,  Yan Yang ,  Michel Klein

发明人： Sheena Loosmore ,  Ken Sasaki ,  Yan Yang ,  Michel Klein

IPC分类号： A61K39/02 ,  C07H21/04 ,  C12P21/06 ,  C12N15/74 ,  C12N1/21 ,  C07K14/195

CPC分类号： C07K14/212

摘要： An isolated and purified outer membrane protein of a Moraxella strain, particularly M. catarrhalis, having a molecular mass of about 200 kDa, is provided by recombinant means. The about 200 kDa outer membrane protein as well as nucleic acid molecules encoding the same are useful in diagnostic applications and immunogenic compositions, particularly for in vivo administration to a host to confer protection against disease caused by a bacterial pathogen that produces the about 200 kDa outer membrane protein or produces a protein capable of inducing antibodies in a host specifically reactive with the about 200 kDa outer membrane protein.

摘要翻译： 通过重组方法提供分离和纯化的分子量为约200kDa的莫拉氏菌属菌株，特别是卡他莫拉氏菌的外膜蛋白。 大约200kDa的外膜蛋白以及编码它们的核酸分子可用于诊断应用和免疫原性组合物，特别是用于体内施用于宿主以赋予产生约200kDa外部细菌病原体引起的疾病的保护 产生能够在与约200kDa外膜蛋白特异性反应的宿主中诱导抗体的蛋白质。

公开(公告)号：US06948075B2

公开(公告)日：2005-09-20

申请号：US09898115

申请日：2001-07-03

申请人： Ken Sasaki ,  Yasuhito Shimizu ,  Hidetoshi Mori

发明人： Ken Sasaki ,  Yasuhito Shimizu ,  Hidetoshi Mori

IPC分类号： G06F1/00 ,  G06F1/24 ,  G06F11/30 ,  G06F11/32 ,  G06F12/14 ,  H04L9/00 ,  H04L9/32

CPC分类号： G06F11/328 ,  G06F21/31

摘要： The present invention provides a control method for notification of tampering of information apparatus, a computer, and/or a storage medium. It provides a technique for storing information related to a starting factor of the information apparatus and/or the computer, as well as notifying a certified user of the information apparatus and/or the computer of the information, thereby reporting and/or preventing the information apparatus and/or the computer from an illegitimate and/or illegal use. It enables a user to know that a computer or other information apparatus has been used and/or tampered by an uncertified user.

摘要翻译： 本发明提供了一种用于通知信息装置，计算机和/或存储介质的篡改的控制方法。 它提供了一种用于存储与信息装置和/或计算机的启动因子相关的信息的技术，以及通知信息装置的认证用户和/或计算机的信息，由此报告和/或防止信息 设备和/或计算机非法和/或非法使用。 它使得用户能够知道计算机或其他信息设备已经被未认证的用户使用和/或被篡改。

公开(公告)号：US06269866B1

公开(公告)日：2001-08-07

申请号：US09544313

申请日：2000-04-06

申请人： Masaaki Yamamoto ,  Jun Niekawa ,  Tatuhiko Ueki ,  Masami Ikeda ,  Ken Sasaki

发明人： Masaaki Yamamoto ,  Jun Niekawa ,  Tatuhiko Ueki ,  Masami Ikeda ,  Ken Sasaki

IPC分类号： F28D1500

CPC分类号： H01L23/3733 ,  F28D15/0233 ,  F28D15/046 ,  H01L23/3672 ,  H01L23/427 ,  H01L2924/0002 ,  H01L2924/00

摘要： The invention provides a cooling device provided with a heat pipe, which is capable of effectively radiating heat from electronic equipment such as a small-sized computer. The cooling device with the heat pipe comprises a plate-like container made of heat transferring metal for containing a working fluid, and having a heat absorbing surface larger than that of the body to be cooled, a the heat transferring metal column, and a hollow portion in which the working fluid exists. An alternating embodiment of the cooling device with the heat pipe comprises a plate-like container made of heat transferring metal, a heat absorbing wall having a large heat absorbing surface, and a plurality of protrusion portions.

摘要翻译： 本发明提供了一种具有热管的冷却装置，其能够有效地从诸如小型计算机的电子设备辐射热量。 具有热管的冷却装置包括由用于容纳工作流体的传热金属制成的板状容器，并且具有比要冷却的物体更大的吸热表面，传热金属柱和中空部 存在工作流体的部分。 具有热管的冷却装置的交替实施例包括由传热金属制成的板状容器，具有大的吸热表面的吸热壁和多个突出部分。

公开(公告)号：US6082443A

公开(公告)日：2000-07-04

申请号：US23372

申请日：1998-02-13

申请人： Masaaki Yamamoto ,  Jun Niekawa ,  Tatuhiko Ueki ,  Masami Ikeda ,  Ken Sasaki

发明人： Masaaki Yamamoto ,  Jun Niekawa ,  Tatuhiko Ueki ,  Masami Ikeda ,  Ken Sasaki

IPC分类号： F28D15/02 ,  H01L23/367 ,  H01L23/373 ,  H01L23/427 ,  F28D15/00

CPC分类号： F28D15/0233 ,  F28D15/046 ,  H01L23/3672 ,  H01L23/3733 ,  H01L23/427 ,  H01L2924/0002

摘要： The invention provides a cooling device with a heat pipe, which is capable of effectively radiating heat from electronic equipment such as a small-sized computer. The cooling device with the heat pipe comprises a plate-like container made of heat transferring metal for containing a working fluid, and having a heat absorbing surface larger than that of the body to be cooled, a heat transferring metal column, and a hollow portion in which the working fluid exists. An alternating embodiment of the cooling device with the heat pipe comprises a plate-like container made of heat transferring metal, a heat absorbing wall having a large heat absorbing surface, and a plurality of protrusion portions.

摘要翻译： 本发明提供了一种具有热管的冷却装置，其能够有效地从诸如小型计算机的电子设备辐射热量。 具有热管的冷却装置包括由用于容纳工作流体的传热金属制成的板状容器，并且具有大于待冷却体的吸热表面的热吸收表面，传热金属柱和中空部分 其中存在工作流体。 具有热管的冷却装置的交替实施例包括由传热金属制成的板状容器，具有大的吸热表面的吸热壁和多个突出部分。

公开(公告)号：US5808024A

公开(公告)日：1998-09-15

申请号：US478370

申请日：1995-06-07

申请人： Ken Sasaki ,  Robin E. Harkness ,  Sheena M. Loosmore ,  Michel H. Klein

发明人： Ken Sasaki ,  Robin E. Harkness ,  Sheena M. Loosmore ,  Michel H. Klein

IPC分类号： A61K39/00 ,  A61K39/095 ,  C07K14/21 ,  C07K14/22 ,  C12N5/10 ,  C12N15/31 ,  C12N15/62 ,  C07H21/02

CPC分类号： C07K14/212 ,  A61K39/00 ,  C07K2319/02 ,  Y10S530/806 ,  Y10S530/825

摘要： An isolated and purified outer membrane protein of a Moraxella strain, particularly M. catarrhalis, has a molecular mass of about 200 kDa. The about 200 kDa outer membrane protein as well as nucleic acid molecules encoding the same are useful in diagnostic applications and immunogenic compositions, particularly for in vivo administration to a host to confer protection against disease caused by a bacterial pathogen that produces the about 200 kDa outer membrane protein or produces a protein capable of inducing antibodies in a host specifically reactive with the about 200 kDa outer membrane protein.

摘要翻译： 分离和纯化的莫拉氏菌属菌株，特别是卡他莫拉氏菌的外膜蛋白具有约200kDa的分子量。 大约200kDa的外膜蛋白以及编码它们的核酸分子可用于诊断应用和免疫原性组合物，特别是用于体内施用于宿主以赋予产生约200kDa外部细菌病原体引起的疾病的保护 产生能够在与约200kDa外膜蛋白特异性反应的宿主中诱导抗体的蛋白质。

公开(公告)号：US5230249A

公开(公告)日：1993-07-27

申请号：US741753

申请日：1991-08-07

申请人： Ken Sasaki ,  Yoshio Ono ,  Etsuro Nakajima ,  Masayoshi Okuyama

发明人： Ken Sasaki ,  Yoshio Ono ,  Etsuro Nakajima ,  Masayoshi Okuyama

IPC分类号： A43B13/20

CPC分类号： A43B13/203 ,  A43B3/0005

摘要： A footwear of the present invention is provided with tank chambers which are disposed to be in contact with an instep, sole and ankle of the user for applying pressure thereto to protect his foot from shocks. The tank chambers are filled with air and air pressure within the tank chambers can be adjusted. The footwear is further provided with a pressure sensor for measuring air pressure within the tank chambers to generate a pressure signal, and a pressure data displaying device for indicating pressure data on the basis of the pressure signal generated by the pressure sensor. Therefore, the user can make sure on the pressure data display device a pressure level at which the most suitable pressure for his foot is obtained. The user is also allowed to extremely easily adjust the air pressure at the above pressure level, watching an indication on the pressure data display device.

摘要翻译： 本发明的鞋类设置有罐室，其被设置成与使用者的脚背，鞋底和脚踝接触，以向其施加压力以保护他的脚免受冲击。 罐室充满空气，可以调节罐室内的空气压力。 该鞋类还设置有用于测量罐室内的空气压力以产生压力信号的压力传感器，以及用于根据压力传感器产生的压力信号指示压力数据的压力数据显示装置。 因此，用户可以在压力数据显示装置上确保获得用于他的脚最适合的压力的压力水平。 还允许用户极其容易地调节在上述压力水平的空气压力，观察压力数据显示装置上的指示。