摘要:
An agent for the prevention and/or treatment of urine collection disorders associated with lower urinary tract obstructive disease, characterized by containing an indoline derivative represented by the following general formula (I): wherein R; R1; and R2 are defined in the specification. The derivative and salt are usable as an agent for the prevention and/or treatment of urine collection disorders associated with lower urinary tract obstructive disease. Silodosin is the preferred indoline derivative.
摘要:
The present invention provides an agent useful for the prevention of transition to surgical therapy for benign prostatic hyperplasia and the like. The present invention relates to a pharmaceutical composition for the prevention of transition to surgical therapy for benign prostatic hyperplasia, which comprises an indoline derivative represented by the following general formula (I) or a pharmaceutically acceptable salt thereof (in the formula, R represents an optionally substituted aliphatic acyl group, a hydroxyalkyl group, an aliphatic acyloxyalkyl group, a substituted lower alkyl group, an optionally substituted aromatic acyl group, a furoyl group, a pyridylcarbonyl group or the like; R1 represents a cyano group or a carbamoyl group; and R2 represents an optionally substituted lower alkyl group).
摘要翻译:本发明提供了可用于预防过渡到良性前列腺增生等的外科治疗的药剂。 本发明涉及一种用于预防过渡到良性前列腺增生的手术治疗的药物组合物,其包含由以下通式(I)表示的二氢吲哚衍生物或其药学上可接受的盐(在该式中,R表示任选的 取代的脂族酰基,羟烷基,脂族酰氧基烷基,取代的低级烷基,任选取代的芳族酰基,糠酰基,吡啶基羰基等; R 1表示氰基 基团或氨基甲酰基; R 2表示任选取代的低级烷基)。
摘要:
The present invention provides a steel product that consists of, by mass %, C: 0.35-0.7%, Si: 0.30-1.1%, Mn: 0.2-2.0%, Al: 0.005-0.25%, Ti: 0.005-0.1%, Mo: 0.05-0.6%, B: 0.0003-0.006%, S: 0.06% or less, P: 0.02% or less, Cr: 0.2% or less, and the balance Fe and inevitable impurities, and has a structure of bainite and/or martensite, the total volume fraction of bainite and martensite being 10% or more, and an induction hardened member that is made of the steel product having a hardened surface layer formed by induction hardening and has a prior austenite grain size of 12 μm or less through the layer thickness. The member has high fatigue strength and therefore is suitable for an automobile drive shaft, an automobile constant velocity joint or the like.
摘要:
A machine structural steel product having superior formability of rotary-forming, torsional properties, and quenching-crack resistance is provided which is manufactured using an electric furnace instead of a blast furnace and which removes adverse influences of tramp elements. A drive shaft having a superior static strength and fatigue strength is provided. In particular, the machine structural steel product contains: on a mass percent basis, C: 0.35% to 0.50%; Si: 0.15% or less; Mn: 0.20% to 1.1%; P: 0.02% or less; S: 0.005% to 0.035%; Cr: more than 0.1% to 0.2%; Mo: 0.05% to 0.5%; Ti: 0.01% to 0.05%; Al: 0.01% to 0.05%; N: 0.01% or less; B: 0.0005% to 0.0050%; Cu: 0.06% to 0.25%; and Ni: 0.05% to 0.2%, and in addition, the composition described above is adjusted so that an LD value represented by the following equation (1) satisfies 120 or less. LD=0.569×{7.98×(C)}1/2×(1+4.1Mn)·(1+2.83P)·(1−0.62S)·(1+0.64Si)·(1+2.33Cr)·(1+0.52Ni)·(1+3.14Mo)·(1+0.27Cu)·(1+1.5(0.9−C))}+52.6 (1)In the above equation, C, Mn, P, S, Si, Cr, Ni, Mo, and Cu in the equation each indicate the content (mass percent) of the respective elements.
摘要:
Provided is a non heat-treated steel that requires no particular controls over cooling rates and no aging treatments after hot working, that can sufficiently increase tensile strength, yield strength and toughness even at lightly deformed parts, and furthermore, that has excellent material anisotropy and machinability as an alloy steel for machine structures. In other words, it is a non heat-treated steel that contains: C: more than 0.05 mass % to less than 0.10 mass %; Si: 1.0 mass % or less; Mn: more than 2.2 mass % to 5.0 mass %; S: less than 0.020 mass %; Cu: more than 1.0 mass % to 3.0 mass %; Ni: 3.0 mass % or less; Cr: 0.01 to 2.0 mass %; Al: 0.1 mass % or less; Ti: 0.01 to 0.10 mass %; B: 0.0003 to 0.03 mass %; N: 0.0010 to 0.0200 mass %; O: 0.0060 mass % or less; and the balance Fe and inevitable impurities, and that the steel structure is bainitic having block structures at 10% or more in area ratios.
摘要:
A micro electro mechanical device includes an inner frame provided with a movable part and an outer frame provided in a circumference of the inner frame. The outer frame has a fixing part fixed by a joining material. A first torsion bar is provided between the outer frame and the inner frame so as to swingably support the inner frame on the outer frame. A first opening is formed in the outer frame in a vicinity of the first torsion bar. The first opening is positioned between the fixing part of the outer frame and the first torsion bar.
摘要:
An optical modulator for modulating light emitted from a signal light source has a substrate having electrooptic effect, an optical waveguide of a Mach-Zehnder type formed on the substrate, an electrode formed on the substrate to control light propagated in the optical waveguide, an interference light generating means for making radiation light radiated from the optical waveguide and signal light leaking from the optical waveguide interfere with each other to generate interference light, and emitting the interference light from an end surface of the substrate, a photo-detector for monitoring the interference light of the radiation light and the signal light, and a signal controlling circuit for controlling an operating point of the optical modulator according to a change of the interference light monitored by the photo-detector It is thereby possible to prevent degradation of a distinction ratio due to a shift of the operating point of the optical modulator so as to allow stable optical modulation, while facilitating a design of the mechanism of the optical modulator.
摘要:
An optical waveguide device including a package housing having an element mounting surface, an element inserting groove opening to the element mounting surface, and a cutout as a space opening to an inner surface of the element inserting groove; and an optical waveguide element having a dielectric substrate, an optical waveguide formed in a surface of the dielectric substrate, and an electrode formed over the surface of the dielectric substrate, the optical waveguide element being inserted and fixed in the element inserting groove of the package housing by using an adhesive. The cutout opens also to the element mounting surface. In applying the adhesive to the bottom surface of the element inserting groove and inserting the optical waveguide element into the element inserting groove, the adhesive flows into the cutout and is prevented from flowing up to the element mounting surface. Further, a working space for application of the adhesive to the bottom surface of the element inserting groove can be ensured by the cutout.
摘要:
We provide a steel product that includes, by mass %, C: 0.35-0.7%, Si: 0.30-1.1%, Mn: 0.2-2.0%, Al: 0.005-0.25%, Ti: 0.005-0.1%, Mo: 0.05-0.6%, B: 0.0003-0.006%, S: 0.06% or less, P: 0.02% or less, Cr: 0.2% or less, and the balance Fe and inevitable impurities, and has a structure of bainite and/or martensite, the total volume fraction of bainite and martensite being 10% or more, and an induction hardened member that is made of the steel product having a hardened surface layer formed by induction hardening and has a prior austenite grain size of 12 μm or less through the layer thickness. The member has high fatigue strength and therefore is suitable for an automobile drive shaft, an automobile constant velocity joint or the like.
摘要:
An optical modulator for modulating light emitted from a signal light source has a substrate having electrooptic effect, an optical waveguide of a Mach-Zehnder type formed on the substrate, an electrode formed on the substrate to control light propagated in the optical waveguide, a light guiding unit for guiding light radiated or leaking from the optical waveguide, an interference light generating means for making light emitted from the light guiding unit and signal light leaking from the optical waveguide interfere with each other to generate interference light, and for emitting the interference light from an end surface of the substrate, a photo-detector for monitoring the interference light obtained by the interference light generating means, and a signal controlling circuit for controlling an operating point of the optical modulator according to a change of the interference light monitored by the photo-detector, thereby stably controlling the operating point of the optical modulator while facilitating a design of the mechanism.