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公开(公告)号：US5791084A
公开(公告)日：1998-08-11
申请号：US933748
申请日：1997-09-23
CPC分类号： A01C1/06
摘要： A method for making a gel coat of gel-coated seed easily disintegrable, in which the gel-coated seed has an aqueous gel layer water-insolubilized with a metal ion, wherein the method comprises blocking the insolubilizing action of the metal ion with a sequestering agent.
摘要翻译： 一种使凝胶涂覆的种子的凝胶涂层容易分解的方法，其中所述凝胶涂覆的种子具有水不溶于金属离子的水性凝胶层，其中所述方法包括用隔离层阻断金属离子的不溶化作用 代理商
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公开(公告)号：US5706602A
公开(公告)日：1998-01-13
申请号：US662084
申请日：1996-06-12
CPC分类号： A01C1/06
摘要： A method for making a gel coat of gel-coated seed easily disintegrable, in which the gel-coated seed has an aqueous gel layer water-insolubilized with a metal ion, wherein the method comprises blocking the insolubilizing action of the metal ion with a sequestering agent.
摘要翻译： 一种使凝胶涂覆的种子的凝胶涂层容易分解的方法，其中所述凝胶涂覆的种子具有水不溶于金属离子的水性凝胶层，其中所述方法包括用隔离层阻断金属离子的不溶化作用 代理商
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公开(公告)号：US5910281A
公开(公告)日：1999-06-08
申请号：US662083
申请日：1996-06-12
摘要： A method for restoring a dried aqueous organic gel capsule which includes aqueous organic gel hardened with a metal ion and then has been solidified by drying, wherein the method comprises immersing the solidified capsule in an aqueous solution containing the metal ion.
摘要翻译： 一种恢复干燥的水性有机凝胶胶囊的方法，其包括用金属离子硬化的水性有机凝胶，然后通过干燥固化，其中所述方法包括将固化的胶囊浸入含有金属离子的水溶液中。
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公开(公告)号：US5701700A
公开(公告)日：1997-12-30
申请号：US679263
申请日：1996-07-12
CPC分类号： A01C1/06
摘要： A method for storing gel-coated seeds having a gel coat comprising an aqueous gel having been water-insolubilized by a metal ion, which comprises storing the gel-coated seeds in an aqueous solution containing the metal ion.
摘要翻译： 一种用于储存凝胶涂覆的种子的方法，所述凝胶涂层包含水溶性凝胶，所述凝胶涂层已被金属离子水不溶化，其包括将所述凝胶涂覆的种子储存在含有金属离子的水溶液中。
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公开(公告)号：US08695409B2
公开(公告)日：2014-04-15
申请号：US13596385
申请日：2012-08-28
申请人： Yasushi Kohno , Takao Ban , Hidehito Tsujii
发明人： Yasushi Kohno , Takao Ban , Hidehito Tsujii
IPC分类号： G01M15/04
CPC分类号： G01F1/6842 , G01F1/698 , G01F1/6983 , G01F5/00
摘要： An air flow rate measuring apparatus includes a heater and a control circuit. The heater heats a part of an intake air sucked into an engine. The control circuit controls an energization of the heater. The heater has a measuring-mode temperature when a flow rate of the intake air is measured. The control circuit has a heat cleaner which temporarily raises a temperature of the heater higher than the measuring-mode temperature when an energization of the air flow rate measuring apparatus is started.
摘要翻译： 空气流量测量装置包括加热器和控制电路。 加热器加热吸入发动机的进气的一部分。 控制电路控制加热器的通电。 当测量进气的流量时，加热器具有测量模式温度。 控制电路具有在开始空气流量测量装置通电时临时使加热器的温度高于测量模式温度的热清洁器。
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公开(公告)号：US20130317065A1
公开(公告)日：2013-11-28
申请号：US13980604
申请日：2012-01-24
申请人： Kazuya Tatani , Atsushi Kondo , Tatsuhiro Kondo , Naohiro Kawamura , Shigeki Seto , Yasushi Kohno
发明人： Kazuya Tatani , Atsushi Kondo , Tatsuhiro Kondo , Naohiro Kawamura , Shigeki Seto , Yasushi Kohno
IPC分类号： A61K31/4439 , C07D401/14 , C07D413/14 , C07D405/06 , C07D417/06 , A61K31/506 , A61K31/444 , A61K31/427 , A61K31/41 , A61K31/4245 , C07D401/06 , C07D405/14 , C07D409/14 , A61K31/404
CPC分类号： A61K31/4245 , A61K31/404 , A61K31/41 , A61K31/427 , A61K31/4439 , A61K31/444 , A61K31/506 , A61K45/06 , C07D209/18 , C07D401/06 , C07D401/14 , C07D403/10 , C07D405/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/06 , C07D419/14 , A61K2300/00
摘要： The present invention provides a compound represented by the general formula (I) of the present invention, which has EP1 receptor antagonism: wherein A represents a benzene ring, a pyridine ring, or the like; Y1 represents a C1-6 alkylene group or the like; Y2 represents a single bond or the like; Z represents —C(═O)—NHSO2R6, an acidic 5-membered hetero ring group, or the like; R1 represents a hydrogen atom or the like; R2 represents a phenyl group, a 5-membered aromatic heterocyclic group, or the like; R3 represents a halogen atom, a C1-6 alkoxy group, or the like; R4 represents a hydrogen atom, a halogen atom, or the like; R5 represents a hydrogen atom or the like; and R6 represents a C1-6 alkyl group or the like], or a pharmaceutically acceptable salt thereof. Furthermore, the compound (I) of the present invention can be used as an agent for treating or preventing LUTS, in particular, various symptoms of OABs.
摘要翻译： 本发明提供了具有EP1受体拮抗作用的本发明通式（I）表示的化合物：其中A表示苯环，吡啶环等; Y1表示C1-6亚烷基等; Y2表示单键等; Z表示-C（= O）-NHSO 2 R 6，酸性5元杂环基等; R1表示氢原子等; R 2表示苯基，5元芳族杂环基等; R3表示卤素原子，C1-6烷氧基等; R 4表示氢原子，卤素原子等; R5表示氢原子等; R6表示C1-6烷基等〕或其药学上可接受的盐。 此外，本发明的化合物（I）可以用作治疗或预防LUTS，特别是OAB的各种症状的药剂。
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7.发明申请PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT 审中-公开含有相同活性成分的吡咯烷酮衍生物和PDE抑制剂公开(公告)号：US20100160335A1
公开(公告)日：2010-06-24
申请号：US12452172
申请日：2008-06-18
申请人： Yasushi Kohno , Koji Ochiai , Satoshi Takita , Akihiko Kojima , Tomohiko Eiraku , Tetsuya Kishi
发明人： Yasushi Kohno , Koji Ochiai , Satoshi Takita , Akihiko Kojima , Tomohiko Eiraku , Tetsuya Kishi
IPC分类号： A61K31/50 , A61K31/501 , C07D403/00
CPC分类号： C07D413/14 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14 , C07D471/04
摘要： It is to provide a novel pyridazinone derivative represented by the following general formula (1), which is useful as a pharmaceutical and has a phosphodiesterase inhibitory action: wherein R1 represents H or C1-6 alkyl, each of R2 and R3 represents H, X, C1-6 alkoxy, Z represents O or S, and A represents AA or BB, wherein AA represents: and BB represents: wherein R4 represents H or C1-6 alkyl, and each of R5 and R6 represents C1-6 alkyl.
摘要翻译： 提供由以下通式（1）表示的新的哒嗪酮衍生物，其可用作药物并具有磷酸二酯酶抑制作用：其中R1表示H或C1-6烷基，R2和R3各自表示H，X C 1-6烷氧基，Z表示O或S，A表示AA或BB，其中AA表示：BB表示：其中R4表示H或C1-6烷基，R5和R6各自表示C1-6烷基。
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8.发明授权公开(公告)号：US07703320B2
公开(公告)日：2010-04-27
申请号：US12120517
申请日：2008-05-14
申请人： Junzo Yamaguchi , Yasushi Kohno
发明人： Junzo Yamaguchi , Yasushi Kohno
IPC分类号： G01F1/68
CPC分类号： G01F1/692
摘要： According to a flow measuring device, first ranges formed by a first plurality of resistors form a single continuous value range on a flow direction coordinate axis. Thus, the first plurality of resistors is limited from being thermally insulated from one another in the flow direction, and thereby detectivity is improved. Also, second ranges formed by a second plurality of resistors form an other single continuous value range on a longitudinal direction coordinate axis. The other continuous value range includes a position that corresponds to a half length of a heating element in a longitudinal direction. As a result, detection difference is obtained at the position, at which a temperature is most optimally detected, and thereby detectivity is further improved.
摘要翻译： 根据流量测量装置，由第一多个电阻器形成的第一范围在流动方向坐标轴上形成单个连续值范围。 因此，第一多个电阻器被限制为在流动方向上彼此热绝缘，从而提高了检测性。 此外，由第二多个电阻器形成的第二范围在纵向坐标轴上形成另一个单个连续值范围。 另一连续值范围包括对应于加热元件在纵向上的半长度的位置。 结果，在最佳检测温度的位置处获得检测差异，从而进一步提高检测性。
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9.发明申请Aminophosphonic acid derivative, salt thereof, and modulator of sip receptor 有权氨基膦酸衍生物，其盐和sip受体的调节剂公开(公告)号：US20080275008A1
公开(公告)日：2008-11-06
申请号：US12213187
申请日：2008-06-16
申请人： Yasushi Kohno , Kiyoaki Tanaka , Kazuhiko Kuriyama , Wataru Hori
发明人： Yasushi Kohno , Kiyoaki Tanaka , Kazuhiko Kuriyama , Wataru Hori
IPC分类号： A61K31/662
CPC分类号： C07C47/575 , C07C45/71 , C07F7/1804 , C07F9/3826 , C07F9/3882 , C07F9/4015 , C07F9/4056 , C07F9/653
摘要： Aminophosphonic acid derivatives (e.g., 2-amino-5-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]-2-methylpentylphosphonate monoester) are represented by the following general formula (1): and act as effective S1P receptor modulators while posing less side effects.
摘要翻译： 氨基膦酸衍生物（例如2-氨基-5- [4-（3-苄氧基苯硫基）-2-氯苯基] -2-甲基戊基膦酸酯单酯）由以下通式（1）表示：作为有效的S1P受体调节剂， 减少副作用。
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公开(公告)号：US06694811B2
公开(公告)日：2004-02-24
申请号：US10379938
申请日：2003-03-06
IPC分类号： G01F168
CPC分类号： G01F1/6842
摘要： A flow meter is formed with a passage for introducing and carrying air to measure and has a sensing part disposed in the passage for measuring a flow rate of the air. A contraction part is formed on an inner surface of the passage so that the contraction part faces the sensing part. The contraction part narrows the flow of the air flowing near the sensing part. A flat surface of the contraction part is formed in parallel with the surface of the sensing part and at least upstream of the sensing part. Thus, collision of particles against the sensing part and adhesion of contaminants to the sensing pert are inhibited. Meanwhile, the flow rate of the air is measured stably and accurately.
摘要翻译： 流量计形成有用于引入和携带空气进行测量的通道，并且具有设置在通道中的用于测量空气流量的感测部分。 收缩部分形成在通道的内表面上，使得收缩部分面向感测部分。 收缩部分使感应部分附近的空气流动变窄。 收缩部分的平坦表面形成为与感测部分的表面平行并且至少在感测部分的上游。 因此，抑制了颗粒与传感部分的碰撞以及污染物与传感污染物的粘附。 同时，稳定且准确地测量空气的流量。
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