-
1.发明授权公开(公告)号：US07420045B1
公开(公告)日：2008-09-02
申请号：US10130555
申请日：2000-11-17
Applicant: Ying Luo , Xiang Xu , Cindy Leo , Betty Huang , Mary Shen
Inventor： Ying Luo , Xiang Xu , Cindy Leo , Betty Huang , Mary Shen
CPC classification number: C07K14/4747 , A61K38/00
Abstract: The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also, provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
Abstract translation: 本发明涉及对细胞周期有影响或与细胞周期有关的新型多肽，核酸和相关分子。 此外，本文提供的是包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及用于产生本发明多肽的方法 本发明。 本发明还提供了鉴定介导细胞周期生物活性的新型组合物的方法，以及这些组合物在疾病诊断和治疗中的应用。
-
2.发明授权公开(公告)号：US06737232B1
公开(公告)日：2004-05-18
申请号：US09442013
申请日：1999-11-17
Applicant: Ying Luo , Xiang Xu , Cindy Leo , Betty Huang , Mary Shen
Inventor： Ying Luo , Xiang Xu , Cindy Leo , Betty Huang , Mary Shen
IPC: C12Q100
CPC classification number: C07K14/4747 , A61K38/00
Abstract: The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
Abstract translation: 本发明涉及对细胞周期有影响或与细胞周期有关的新型多肽，核酸和相关分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本发明还提供了鉴定介导细胞周期生物活性的新型组合物的方法，以及这些组合物在疾病诊断和治疗中的应用。
-
3.发明授权公开(公告)号：US07423118B1
公开(公告)日：2008-09-09
申请号：US09715725
申请日：2000-11-16
Applicant: Ying Luo , Xiang Xu , Cindy Leo , Betty Huang , Mary Shen
Inventor： Ying Luo , Xiang Xu , Cindy Leo , Betty Huang , Mary Shen
IPC: C07K14/00
CPC classification number: C07K14/4747 , A61K38/00
Abstract: The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
Abstract translation: 本发明涉及对细胞周期有影响或与细胞周期有关的新型多肽，核酸和相关分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本发明还提供了鉴定介导细胞周期生物活性的新型组合物的方法，以及这些组合物在疾病诊断和治疗中的应用。
-
公开(公告)号：US20050074825A1
公开(公告)日：2005-04-07
申请号：US10616101
申请日：2003-07-08
Applicant: Ying Luo , Eva Chan , Xiang Xu , Betty Huang , Valeria Ossovskaya
Inventor： Ying Luo , Eva Chan , Xiang Xu , Betty Huang , Valeria Ossovskaya
IPC: A61K38/00 , C12N9/10 , G01N33/574
CPC classification number: C12N9/1077 , A61K38/00 , C12N2310/111
Abstract: The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
-
5.发明授权公开(公告)号：US06887675B1
公开(公告)日：2005-05-03
申请号：US09843159
申请日：2001-04-25
Applicant: Ying Luo , Eva Chan , Xiang Xu , Betty Huang , Valeria Ossovskaya
Inventor： Ying Luo , Eva Chan , Xiang Xu , Betty Huang , Valeria Ossovskaya
CPC classification number: C12N9/1077 , A61K38/00 , C12N2310/111
Abstract: The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
Abstract translation: 本发明涉及对细胞周期有影响或与细胞周期有关的新型多肽，核酸和相关分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本发明还提供了鉴定介导细胞周期生物活性的新组合物的方法，以及这些组合物在疾病诊断和治疗中的应用。
-
Patent Agency Ranking
公开(公告)号：US20060228761A1
公开(公告)日：2006-10-12
申请号：US11295841
申请日：2005-12-06
Applicant: Ying Luo , Pei Yu , Mary Shen , Betty Huang
Inventor： Ying Luo , Pei Yu , Mary Shen , Betty Huang
CPC classification number: C12N9/1205 , C07K14/4738 , C07K16/18
Abstract: The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
-
公开(公告)号：US06617102B1
公开(公告)日：2003-09-09
申请号：US09696668
申请日：2000-10-25
Applicant: Ying Luo , Eva Chan , Xiang Xu , Betty Huang , Valeria Ossovskaya
Inventor： Ying Luo , Eva Chan , Xiang Xu , Betty Huang , Valeria Ossovskaya
IPC: C12Q100
CPC classification number: C12N9/1077 , A61K38/00 , C12N2310/111
Abstract: The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
-
8.发明授权公开(公告)号：US06589725B1
公开(公告)日：2003-07-08
申请号：US09427154
申请日：1999-10-25
Applicant: Ying Luo , Eva Chan , Xiang Xu , Betty Huang
Inventor： Ying Luo , Eva Chan , Xiang Xu , Betty Huang
IPC: C12Q100
CPC classification number: C12N9/1077 , A61K38/00 , C12N2310/111
Abstract: The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
Abstract translation: 本发明涉及对细胞周期有影响或与细胞周期有关的新型多肽，核酸和相关分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本发明还提供了鉴定介导细胞周期生物活性的新型组合物的方法，以及这些组合物在疾病诊断和治疗中的应用。
-
公开(公告)号：US07488805B2
公开(公告)日：2009-02-10
申请号：US11739267
申请日：2007-04-24
Applicant: Ying Luo , Betty Huang , Mary Shen , Pei Wen Yu
Inventor： Ying Luo , Betty Huang , Mary Shen , Pei Wen Yu
IPC: C07K16/00
CPC classification number: C07K14/4747 , A61K38/00
Abstract: The present invention is directed to novel apoptosis polypeptides such as the Apop1, Apop2, and Apop3 proteins and related molecules which are involved in modulating apoptosis and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are method for identifying novel compositions which modulate the biological activity of Apop1, Apop2, and Apop3, and the use of such compositions in diagnosis and treatment of disease.
Abstract translation: 本发明涉及新的凋亡多肽，例如参与调节凋亡的Apop1，Apop2和Apop3蛋白和相关分子以及编码这些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本发明还提供了鉴定调节Apop1，Apop2和Apop3的生物学活性的新组合物的方法，以及这些组合物在疾病诊断和治疗中的用途。
-
公开(公告)号：US07223850B1
公开(公告)日：2007-05-29
申请号：US09762491
申请日：1999-08-06
Applicant: Ying Luo , Betty Huang , Mary Shen , Pei Wen Yu
Inventor： Ying Luo , Betty Huang , Mary Shen , Pei Wen Yu
CPC classification number: C12N9/12
Abstract: The present invention is directed to novel apoptosis polypeptides such as the Apop1, and Apop3 proteins and related molecules which are involved in modulating apoptosis and to nucleic acid molecules encoding those polypeptides. Also provided here are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which modulate the biological activity of Apop1, Apop2, and Apop3, and the use of such compositions in diagnosis and treatment of disease.
Abstract translation: 本发明涉及新的凋亡多肽，例如涉及调节凋亡的Apop1和Apop3蛋白和相关分子以及编码那些多肽的核酸分子。 此处还提供了包含这些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本发明进一步提供了用于鉴定调节Apop1，Apop2和Apop3的生物活性的新组合物的方法，以及这些组合物在诊断和治疗疾病中的用途。
-
-
-
-
-
-
-
-
-
Search Results
17
records
(took 0.029 seconds)
