公开(公告)号：US20100217178A1

公开(公告)日：2010-08-26

申请号：US12389751

申请日：2009-02-20

申请人： Ying-Cheng Lo ,  Alp Akonur ,  Isaac Martis ,  Andrew C. Hayes

发明人： Ying-Cheng Lo ,  Alp Akonur ,  Isaac Martis ,  Andrew C. Hayes

IPC分类号： A61M1/28 ,  G06N5/02 ,  G06F17/10 ,  G06G7/60

CPC分类号： A61M1/28 ,  A61M1/1613 ,  A61M1/287 ,  G06F19/3481 ,  G16H50/50

摘要： A method for peritoneal dialysis treatment includes (i) predicting results of a plurality of patient therapy outcomes for a plurality of different mixed dextrose level dialysis solutions; (ii) selecting one of the mixed dextrose level solutions for a patient based on the results; and (iii) performing at least one therapy using different unmixed dextrose level solutions that combine to simulate a like cumulative concentration that would be achieved using the selected mixed dextrose level solution.

摘要翻译： 腹膜透析治疗的方法包括（i）预测多种不同混合葡萄糖水平透析溶液的多种患者治疗结果的结果; （ii）基于结果选择患者的混合葡萄糖水平溶液之一; 和（iii）使用不同混合葡萄糖水平溶液进行至少一种治疗，其组合以模拟使用所选择的混合葡萄糖水平溶液将达到的类似累积浓度。

公开(公告)号：US09348975B2

公开(公告)日：2016-05-24

申请号：US12431458

申请日：2009-04-28

申请人： Ying-Cheng Lo ,  Alp Akonur ,  Isaac Martis

发明人： Ying-Cheng Lo ,  Alp Akonur ,  Isaac Martis

IPC分类号： G06F19/00 ,  A61M1/28

CPC分类号： G06F19/3481 ,  A61M1/28 ,  A61M1/281 ,  A61M1/282 ,  A61M2205/3569 ,  A61M2205/52 ,  A61M2205/6018 ,  A61M2205/6054 ,  A61M2205/6072 ,  G06F19/00

摘要： Peritoneal dialysis therapy outcomes have been calculated for a variety of dwell times of peritoneal dialysis fluids in the peritoneal cavities of dialysis patients using kinetic modeling. The length of dwell time should not be the same for every patient, but should vary according to the patient condition and needs. Some patients have a potential for expressing greater ultrafiltrate into the dialysis fluid, and these patients can benefit from a longer dwell time, whereas other patients with less potential will not benefit from a longer dwell time. An optimal or peak time is observed for each peritoneal dialysis therapy outcome, such as ultrafiltrate volume rate, urea clearance (Kt/V), and creatinine clearance, while minimizing hydrocarbon absorption. These values and input parameters can be used to tailor the peritoneal dialysis dwell time for each patient, estimating the peak dwell time that will yield the best therapy outcome for each patient.

摘要翻译： 已经使用动力学模型计算了透析患者腹膜腔腹膜透析液的各种停留时间的腹膜透析治疗结果。 每个患者的停留时间长度不应相同，但应根据患者情况和需要而变化。 一些患者有可能在透析液中表达更多的超滤液，这些患者可以从更长的停留时间中受益，而潜在的潜力较小的患者不会受益于更长的停留时间。 对于每个腹膜透析治疗结果，观察到最佳或高峰时间，例如超滤液体积率，尿素清除率（Kt / V）和肌酐清除率，同时使烃吸收最小化。 这些值和输入参数可用于定制每个患者的腹膜透析停留时间，估计将为每位患者产生最佳治疗结果的峰值停留时间。

公开(公告)号：US20090275881A1

公开(公告)日：2009-11-05

申请号：US12431458

申请日：2009-04-28

申请人： Ying-Cheng Lo ,  Alp Akonur ,  Isaac Martis

发明人： Ying-Cheng Lo ,  Alp Akonur ,  Isaac Martis

IPC分类号： A61M1/28 ,  A61B5/00 ,  A61B5/107 ,  G06F17/10 ,  G06F17/30

CPC分类号： G06F19/3481 ,  A61M1/28 ,  A61M1/281 ,  A61M1/282 ,  A61M2205/3569 ,  A61M2205/52 ,  A61M2205/6018 ,  A61M2205/6054 ,  A61M2205/6072 ,  G06F19/00

摘要： Peritoneal dialysis therapy outcomes have been calculated for a variety of dwell times of peritoneal dialysis fluids in the peritoneal cavities of dialysis patients using kinetic modeling. The length of dwell time should not be the same for every patient, but should vary according to the patient condition and needs. Some patients have a potential for expressing greater ultrafiltrate into the dialysis fluid, and these patients can benefit from a longer dwell time, whereas other patients with less potential will not benefit from a longer dwell time. An optimal or peak time is observed for each peritoneal dialysis therapy outcome, such as ultrafiltrate volume rate, urea clearance (Kt/V), and creatinine clearance, while minimizing hydrocarbon absorption. These values and input parameters can be used to tailor the peritoneal dialysis dwell time for each patient, estimating the peak dwell time that will yield the best therapy outcome for each patient.

摘要翻译： 已经使用动力学模型计算了透析患者腹膜腔腹膜透析液的各种停留时间的腹膜透析治疗结果。 每个患者的停留时间长度不应相同，但应根据患者情况和需要而变化。 一些患者有可能在透析液中表达更多的超滤液，这些患者可以从更长的停留时间中受益，而潜在的潜力较小的患者不会受益于更长的停留时间。 对于每个腹膜透析治疗结果观察到最佳或高峰时间，例如超滤液体积率，尿素清除率（Kt / V）和肌酐清除率，同时使烃吸收最小化。 这些值和输入参数可用于定制每个患者的腹膜透析停留时间，估计将为每位患者产生最佳治疗结果的峰值停留时间。