公开(公告)号：US07257433B2

公开(公告)日：2007-08-14

申请号：US10768680

申请日：2004-02-02

申请人： Yoshiaki Takamura ,  Naoki Kobayashi ,  Sunao Takeda ,  Takashi Usuda

发明人： Yoshiaki Takamura ,  Naoki Kobayashi ,  Sunao Takeda ,  Takashi Usuda

IPC分类号： A61B5/00

CPC分类号： A61B5/14551 ,  G01N2021/3144

摘要： An apparatus for measuring a concentration of a light-absorbing substance in blood is disclosed. A light emitter emits light beams to irradiate a living tissue, each of the light beams being associated with one wavelength which is absorbed by the blood. A first instrument measures first intensities of the light beams, which are to be incident on the living tissue. A second instrument measures second intensities of the light beams, which are transmitted through the living tissue. A first calculator calculates an attenuation variation ratio, which is a ratio of attenuation variations of the respective light beams due to variation of a volume of the blood caused by pulsation, based on the second intensities of the light beams. A second calculator calculates the concentration based on the first intensities, the second intensities, and the attenuation variation ratio.

摘要翻译： 公开了一种用于测量血液中光吸收物质浓度的装置。 光发射器发射光束以照射活组织，每个光束与由血液吸收的一个波长相关联。 第一个仪器测量将要入射到活体组织上的光束的第一强度。 第二种仪器测量透过活组织的光束的第二强度。 第一计算器基于光束的第二强度计算衰减变化比，其是由于由脉动引起的血液的体积的变化引起的各个光束的衰减变化的比率。 第二计算器基于第一强度，第二强度和衰减变化率来计算浓度。

公开(公告)号：US06622095B2

公开(公告)日：2003-09-16

申请号：US10075623

申请日：2002-02-15

申请人： Naoki Kobayashi ,  Takashi Usuda ,  Michio Kanemoto ,  Yoshiaki Takamura ,  Teiji Ukawa

发明人： Naoki Kobayashi ,  Takashi Usuda ,  Michio Kanemoto ,  Yoshiaki Takamura ,  Teiji Ukawa

IPC分类号： A61B500

CPC分类号： A61B5/14551

摘要： An apparatus for determining concentrations of hemoglobins includes a light source for emitting lights of at least three different wavelengths, a first wavelength in a near-infrared region, a second wavelength in a red region, and a third wavelength in a red orange region, light receiving device for receiving light emitted by the light source, transmitted through a living tissue or reflected by the living tissue, attenuation ratio processing device for processing attenuation ratios between the wavelengths in accordance with variations of received-light output signals in each of the wavelengths output from the light receiving device, the variations are caused by a pulsation of blood and concentration ratio processing device for processing concentration ratios of at least oxyhemoglobin and methemoglobin based on the output signals from the attenuation ratio processing device.

公开(公告)号：US20090326338A1

公开(公告)日：2009-12-31

申请号：US12495750

申请日：2009-06-30

申请人： Naofumi Kobayashi ,  Sunao Takeda ,  Naoki Kobayashi

发明人： Naofumi Kobayashi ,  Sunao Takeda ,  Naoki Kobayashi

IPC分类号： A61B5/00

CPC分类号： G01N33/497 ,  A61B5/083 ,  G01N2001/2282 ,  G01N2001/4033

摘要： A method of analyzing a gas component derived from living body, includes: extracting a first gas component from a gas contained in an atmosphere by a first method and removing the extracted first gas component from the gas to defecate the atmosphere; obtaining a mixed gas of the defecated atmosphere and a second gas component from a subject; extracting the first gas component from the mixed gas by a second method; and analyzing the first gas component extracted from the mixed gas. The second method is the same as the first method.

摘要翻译： 一种分析来自生物体的气体成分的方法，包括：通过第一种方法从包含在气氛中的气体中提取第一气体成分，并从所述气体中除去所提取的第一气体成分，使大气排出; 从受试者获得排便气体和第二气体成分的混合气体; 通过第二种方法从混合气体提取第一气体组分; 并分析从混合气体中提取的第一气体成分。 第二种方法与第一种方法相同。

公开(公告)号：US07313426B2

公开(公告)日：2007-12-25

申请号：US11090239

申请日：2005-03-28

申请人： Sunao Takeda ,  Naoki Kobayashi ,  Hiroshi Kubota

发明人： Sunao Takeda ,  Naoki Kobayashi ,  Hiroshi Kubota

IPC分类号： A61B5/00

CPC分类号： A61B5/14551 ,  A61B5/14532 ,  A61B2560/0209

摘要： In an apparatus for determining a concentration of a light absorbing substance in blood, a plurality of photo emitters are adapted to emit light beams having different wavelengths toward a living tissue including a blood vessel. A photo receiver is adapted to receive the light beams which have been transmitted through or reflected from the living tissue. A driver inputs driving currents for causing the respective photo emitters to emit the light beams. An optimizer obtains values of AC components of the light beams received by the photo receiver, and adjusts values of the driving currents such that the values of the AC components fall within a predetermined range.

摘要翻译： 在用于测定血液中的光吸收物质的浓度的装置中，多个光发射器适于向包括血管的生物体组织发射具有不同波长的光束。 光接收器适于接收已经通过活体组织传播或反射的光束。 A驱动器输入用于使各个光发射器发射光束的驱动电流。 优化器获得由光接收器接收的光束的AC分量的值，并且调整驱动电流的值，使得AC分量的值落在预定范围内。

公开(公告)号：US08649837B2

公开(公告)日：2014-02-11

申请号：US12175413

申请日：2008-07-17

申请人： Yoshihiro Sugo ,  Naoki Kobayashi ,  Sunao Takeda

发明人： Yoshihiro Sugo ,  Naoki Kobayashi ,  Sunao Takeda

IPC分类号： A61B5/00

CPC分类号： A61B5/14551 ,  A61B5/02416 ,  A61B5/7257

摘要： In order to measure a pulse rate and an oxygen saturation of a subject who is in an exercised state, each of two pulse wave signals obtained from the subject is separated into a signal component and a noise component. A frequency spectrum of the signal component and a frequency spectrum of the noise component are obtained. It is judged whether a body motion of the subject is occurred based on the frequency spectrum of the signal component and the frequency spectrum of the noise component. A pulsation frequency is determined based on the judgment as to the body motion. The pulse rate is calculated based on the pulsation frequency. The oxygen saturation is calculated based on a ratio of spectra of the two pulse wave signals corresponding to the pulsation frequency.

摘要翻译： 为了测量处于锻炼状态的受试者的脉搏率和氧饱和度，从被检体获得的两个脉搏波信号中的每一个被分离为信号分量和噪声分量。 获得信号分量的频谱和噪声分量的频谱。 基于信号分量的频谱和噪声分量的频谱，判断是否发生被检体的体动。 基于关于身体运动的判断来确定脉动频率。 脉搏频率基于脉动频率计算。 基于对应于脉动频率的两个脉波信号的频谱比计算氧饱和度。

公开(公告)号：US20050250997A1

公开(公告)日：2005-11-10

申请号：US11090239

申请日：2005-03-28

申请人： Sunao Takeda ,  Naoki Kobayashi ,  Hiroshi Kubota

发明人： Sunao Takeda ,  Naoki Kobayashi ,  Hiroshi Kubota

IPC分类号： A61B5/00 ,  A61B5/0245 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/35 ,  G01N21/359

CPC分类号： A61B5/14551 ,  A61B5/14532 ,  A61B2560/0209

摘要： In an apparatus for determining a concentration of a light absorbing substance in blood, a plurality of photo emitters are adapted to emit light beams having different wavelengths toward a living tissue including a blood vessel. A photo receiver is adapted to receive the light beams which have been transmitted through or reflected from the living tissue. A driver inputs driving currents for causing the respective photo emitters to emit the light beams. An optimizer obtains values of AC components of the light beams received by the photo receiver, and adjusts values of the driving currents such that the values of the AC components fall within a predetermined range.

摘要翻译： 在用于测定血液中的光吸收物质的浓度的装置中，多个光发射器适于向包括血管的生物体组织发射具有不同波长的光束。 光接收器适于接收已经通过活体组织传播或反射的光束。 A驱动器输入用于使各个光发射器发射光束的驱动电流。 优化器获得由光接收器接收的光束的AC分量的值，并且调整驱动电流的值，使得AC分量的值落在预定范围内。

公开(公告)号：US10349842B2

公开(公告)日：2019-07-16

申请号：US13211390

申请日：2011-08-17

申请人： Takashi Usuda ,  Yoshiharu Kikuchi ,  Hideaki Hirahara ,  Naoki Kobayashi ,  Katsuyoshi Suzuki

发明人： Takashi Usuda ,  Yoshiharu Kikuchi ,  Hideaki Hirahara ,  Naoki Kobayashi ,  Katsuyoshi Suzuki

IPC分类号： A61B5/02 ,  A61B5/0225 ,  A61B5/021 ,  A61B5/022

摘要： A blood pressure measuring apparatus, which measures a blood pressure of a living body, includes: a cuff-pressure control unit which controls a cuff pressure of a cuff that presses a part of the living body; an oscillation signal detection unit which detects an oscillation signal from the cuff pressure; a blood pressure specification unit which specifies systolic and diastolic blood pressures as the blood pressure of the living body from the oscillation signal; and a blood pressure determination unit which determines whether systolic and diastolic blood pressures are appropriate or not. The cuff-pressure control unit controls the cuff pressure to be inflated to a first set value, the blood pressure specification unit specifies the systolic and diastolic blood pressures based on a change of an oscillation signal that is detected by the oscillation signal detection unit when the cuff pressure is inflated to the first set value, and when the blood pressure determination unit determines that both the systolic and diastolic blood pressures are appropriate, the cuff-pressure control unit ends the inflating of the cuff pressure to release the cuff pressure.

公开(公告)号：US09615774B2

公开(公告)日：2017-04-11

申请号：US13526959

申请日：2012-06-19

申请人： Naoki Kobayashi ,  Masayuki Inoue ,  Hidetoshi Dainobu ,  Toshiki Aoki ,  Kumi Sugiyama ,  Iwao Takahashi ,  Kazumasa Ito ,  Takashi Usuda

发明人： Naoki Kobayashi ,  Masayuki Inoue ,  Hidetoshi Dainobu ,  Toshiki Aoki ,  Kumi Sugiyama ,  Iwao Takahashi ,  Kazumasa Ito ,  Takashi Usuda

IPC分类号： A61B5/08 ,  A61B5/00 ,  A61B5/083

CPC分类号： A61B5/082 ,  A61B5/0075 ,  A61B5/0836 ,  A61B5/6803 ,  A61B5/6814

摘要： A CO2 sensor includes: a sensing portion operable to change in color in accordance with a CO2 partial pressure in expiration from at least one of nares and a mouth of a living body; and a mounting member adapted to hold the sensing portion at a position where the expiration from the at least one of the nares and the mouth impinges on the sensing portion.

公开(公告)号：US06415236B1

公开(公告)日：2002-07-02

申请号：US09725865

申请日：2000-11-30

申请人： Naoki Kobayashi ,  Michio Kanemoto ,  Takashi Usuda ,  Teiji Ukawa

发明人： Naoki Kobayashi ,  Michio Kanemoto ,  Takashi Usuda ,  Teiji Ukawa

IPC分类号： A61B500

摘要： An apparatus for determining concentrations of hemoglobins additionally uses a light source 3 which emits light of a third wavelength in an orangy red wavelength region of 590 to 660 nm. The apparatus includes light receiving means 6 for receiving lights that are emitted by the light sources and transmitted through or reflected by a living tissue, attenuation ratio processing means 15 for processing attenuation ratios &PHgr; on the wavelengths based on variations of signals associated with the wavelengths output from the light receiving means, which variations are caused by a pulsation of blood, and concentration ratio processing means 16 for processing concentration ratios of at least oxyhemoglobin, deoxyhemoglobin and carboxyhemoglobin based on the output signals from the attenuation ratio processing means. The apparatus thus constructed can properly measure carboxyhemoglobin COHb, and present its concentration display and an alarm display in a simple manner, which is clinically effective.

公开(公告)号：US09493683B2

公开(公告)日：2016-11-15

申请号：US13382837

申请日：2010-07-08

申请人： Naoki Kobayashi ,  Mikio Konno ,  Daisuke Nagao ,  Yoshihiro Mashiko ,  Toshiaki Otsu

发明人： Naoki Kobayashi ,  Mikio Konno ,  Daisuke Nagao ,  Yoshihiro Mashiko ,  Toshiaki Otsu

IPC分类号： C08L11/02 ,  C08L11/00 ,  C09J111/02 ,  C08F2/24 ,  C08F2/22 ,  C08F2/26 ,  C08F36/18

CPC分类号： C09J111/02 ,  C08F2/22 ,  C08F2/24 ,  C08F2/26 ,  C08F36/18

摘要： Provided is a polychloroprene latex extremely superior in adhesion properties.According to the present invention, chloroprene or a mixture of chloroprene and a monomer copolymerizable with chloroprene is polymerized in the presence of a surfactant in an aqueous medium, in which the surfactant's concentration is lower than its critical micelle concentration (CMC) to obtain a polychloroprene latex. The polychloroprene latex produced according to the present invention is extremely superior in adhesion properties and others and give a smaller amount of deposits during production.

摘要翻译： 根据本发明，氯丁二烯或可与氯丁二烯共聚的单体的混合物在表面活性剂存在下在水性介质中聚合，其中表面活性剂的浓度低于其临界胶束浓度（CMC）以获得聚氯丁二烯 胶乳。 根据本发明生产的聚氯丁二烯胶乳在粘合性能等方面非常优异，并且在生产过程中产生较少量的沉积物。