Dermal pharmaceutical preparations
    1.
    发明授权
    Dermal pharmaceutical preparations 失效
    皮肤药物制剂

    公开(公告)号:US4954343A

    公开(公告)日:1990-09-04

    申请号:US406200

    申请日:1989-09-12

    IPC分类号: A61K9/70 A61L15/58

    CPC分类号: A61K9/7061 A61L15/58

    摘要: A dermal pharmaceutical preparation comprising a soft support having provided thereon a pressure-sensitive adhesive layer containing a pressure-sensitive adhesive and a drug, wherein said pressure-sensitive adhesive is a copolymer comprising a (meth)acrylamide having an amino group as a comonomer unit. The preparation remains the drug in a dissolved state and is excellent in drug liberation and adhesion to the skin.

    摘要翻译: 一种皮肤药物制剂,其包含在其上设置有含有压敏粘合剂和药物的压敏粘合剂层的软质载体,其中所述压敏粘合剂是包含具有氨基作为共聚单体单元的(甲基)丙烯酰胺的共聚物 。 制剂保持药物溶解状态,药物释放和对皮肤的粘附性优异。

    Adiponectin expression-inducing agents and uses thereof
    3.
    发明申请
    Adiponectin expression-inducing agents and uses thereof 失效
    脂联素表达诱导剂及其用途

    公开(公告)号:US20070203061A1

    公开(公告)日:2007-08-30

    申请号:US10594969

    申请日:2005-03-31

    摘要: The present invention provides adiponectin expression-inducing agents, and therapeutic agents using the same for obesity and obesity-related diseases such as cardiovascular diseases or metabolic diseases, as well as methods of searching for adiponectin expression-inducing agents. KLF9, which can bind to the 32-bp fragment of position −188 to position −157 from the adiponectin expression start site, was demonstrated to enhance adiponectin promoter activity. Therefore, the present invention uses KLF9 as an adiponectin expression-inducing agent, and suggests that KLF9 replenishment therapy is useful for preventing and/or treating obesity or obesity-related diseases including metabolic diseases such as insulin resistance and type II diabetes, and cardiovascular diseases.

    摘要翻译: 本发明提供了脂联素表达诱导剂和使用其的治疗剂用于肥胖症和肥胖相关疾病如心血管疾病或代谢疾病,以及搜索脂联素表达诱导剂的方法。 KLF9可以结合位点-188的32-bp片段,从脂联素表达起始位点到位置-157,证明增强脂连蛋白启动子活性。 因此,本发明使用KLF9作为脂联素表达诱导剂,并且表明KLF9补充疗法可用于预防和/或治疗肥胖症或肥胖相关疾病,包括诸如胰岛素抵抗和II型糖尿病等代谢疾病和心血管疾病 。

    COOLING UNIT, COOLING APPARATUS, AND PROJECTION DISPLAY APPARATUS
    5.
    发明申请
    COOLING UNIT, COOLING APPARATUS, AND PROJECTION DISPLAY APPARATUS 审中-公开
    冷却装置,冷却装置和投影显示装置

    公开(公告)号:US20120133907A1

    公开(公告)日:2012-05-31

    申请号:US13307837

    申请日:2011-11-30

    IPC分类号: G03B21/16 F28D15/00

    CPC分类号: G03B21/16

    摘要: A projection display apparatus comprising: a housing member that accommodates an illumination optical unit; a projection optical unit; and a cooling unit, wherein the housing member includes a layout space in a virtually columnar shape having a bottom that is a circumscribed circle of the projection optical unit in a cross sectional view vertical to the projection optical unit; the layout space includes a first layout space in a substantially conical shape and a second layout space excluding the first layout space; the projection optical unit is provided in the first layout space; and at least a part of the illumination optical unit and the cooling unit is provided in the second layout space; and the illumination optical unit and the cooling unit are disposed in a symmetrical positional relationship with respect to the projection optical unit.

    摘要翻译: 一种投影显示装置,包括:容纳照明光学单元的壳体构件; 投影光学单元; 以及冷却单元,其中所述壳体构件包括具有垂直于所述投影光学单元的横截面视图中具有作为所述投影光学单元的外接圆的底部的虚拟柱状形状的布局空间; 布局空间包括大致圆锥形的第一布局空间和除第一布局空间之外的第二布局空间; 投影光学单元设置在第一布局空间中; 并且所述照明光学单元和所述冷却单元的至少一部分设置在所述第二布局空间中; 并且照明光学单元和冷却单元相对于投影光学单元设置成对称的位置关系。

    Genes encoding plant transcription factors
    6.
    发明授权
    Genes encoding plant transcription factors 有权
    编码植物转录因子的基因

    公开(公告)号:US07842854B2

    公开(公告)日:2010-11-30

    申请号:US11453724

    申请日:2006-06-15

    IPC分类号: C12N15/29 C12N15/82

    摘要: Identification of a gene from monocotyledonous plants such as rice, which codes for a transcription factor specific to a stress tolerant gene and provision of a novel environmental stress tolerant plant using the gene. From the rice genome, a gene, which binds to a cis element existing upstream of the gene encoding a stress responsive protein and for a transcription factor to activate the transcription of the gene, is identified. Further, the gene of the transcription factor is used to transform a plant, thereby improving tolerance against environmental stresses such as low temperature, dehydration, and salt stresses.

    摘要翻译: 鉴定来自单子叶植物如水稻的基因,其编码对胁迫耐受基因特异性的转录因子,并提供使用该基因的新型环境胁迫耐受植物。 从水稻基因组中鉴定了与编码应激反应蛋白的基因上游存在的顺式元件和激活基因转录的转录因子结合的基因。 此外,转录因子的基因用于转化植物,从而改善对环境胁迫的耐受性,例如低温,脱水和盐胁迫。

    Adiponectin expression-inducing agents and uses thereof
    7.
    发明授权
    Adiponectin expression-inducing agents and uses thereof 失效
    脂联素表达诱导剂及其用途

    公开(公告)号:US07741080B2

    公开(公告)日:2010-06-22

    申请号:US10594969

    申请日:2005-03-31

    IPC分类号: C12P19/34 C12N15/00 C07H21/04

    摘要: The present invention provides adiponectin expression-inducing agents, and therapeutic agents using the same for obesity and obesity-related diseases such as cardiovascular diseases or metabolic diseases, as well as methods of searching for adiponectin expression-inducing agents.KLF9, which can bind to the 32-bp fragment of position −188 to position −157 from the adiponectin expression start site, was demonstrated to enhance adiponectin promoter activity. Therefore, the present invention uses KLF9 as an adiponectin expression-inducing agent, and suggests that KLF9 replenishment therapy is useful for preventing and/or treating obesity or obesity-related diseases including metabolic diseases such as insulin resistance and type II diabetes, and cardiovascular diseases.

    摘要翻译: 本发明提供了脂联素表达诱导剂和使用其的治疗剂用于肥胖症和肥胖相关疾病如心血管疾病或代谢疾病,以及搜索脂联素表达诱导剂的方法。 KLF9可以结合位点-188的32-bp片段,从脂联素表达起始位点到位置-157,证明增强脂连蛋白启动子活性。 因此,本发明使用KLF9作为脂联素表达诱导剂,并且表明KLF9补充疗法可用于预防和/或治疗肥胖症或肥胖相关疾病,包括诸如胰岛素抵抗和II型糖尿病等代谢疾病和心血管疾病 。

    Genes encoding plant transcription factors
    8.
    发明授权
    Genes encoding plant transcription factors 有权
    编码植物转录因子的基因

    公开(公告)号:US07138277B2

    公开(公告)日:2006-11-21

    申请号:US10302382

    申请日:2002-11-22

    IPC分类号: A01H5/00 C12N15/82

    摘要: Identification of a gene from monocotyledonous plants such as rice, which codes for a transcription factor specific to a stress tolerant gene and provision of a novel environmental stress tolerant plant using the gene. From the rice genome, a gene, which binds to a cis element existing upstream of the gene encoding a stress responsive protein and for a transcription factor to activate the transcription of the gene, is identified. Further, the gene of the transcription factor is used to transform a plant, thereby improving tolerance against environmental stresses such as low temperature, dehydration, and salt stresses.

    摘要翻译: 鉴定来自单子叶植物如水稻的基因,其编码对胁迫耐受基因特异性的转录因子,并提供使用该基因的新型环境胁迫耐受植物。 从水稻基因组中鉴定了与编码应激应答蛋白的基因上游存在的顺式元件和激活基因转录的转录因子结合的基因。 此外,转录因子的基因用于转化植物,从而改善对环境胁迫的耐受性,例如低温,脱水和盐胁迫。