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    Stress-induced promoter and method of using the same
    3.
    发明申请
    Stress-induced promoter and method of using the same 有权
    应激诱导启动子及其使用方法

    公开(公告)号：US20060206966A1

    公开(公告)日：2006-09-14

    申请号：US10550584

    申请日：2004-03-02

    申请人： Kazuko Shinozaki ,  Koji Katsura ,  Yusuke Ito

    发明人： Kazuko Shinozaki ,  Koji Katsura ,  Yusuke Ito

    IPC分类号： A01H1/00 ,  A01H5/00 ,  C12N15/82

    CPC分类号： C12N15/8237

    摘要： This invention provides a stress-inducible promoter that effectively functions in monocotyledonous plants such as rice, and environmental stress-tolerant plants using the promoter. Such promoter is derived from rice and consists of the following DNA (a) or (b): (a) DNA that consists of the nucleotide sequence as shown in SEQ ID NO: 1 or 10; or (b) DNA that hybridizes under stringent conditions with DNA consisting of a nucleotide sequence that is complementary to the DNA consisting of the nucleotide sequence as shown in SEQ ID NO: 1 or 10 and that expresses stress-inducible promoter activity. Such environmental stress-tolerant plant has had such promoter introduced therein.

    摘要翻译： 本发明提供了在单子叶植物如水稻和使用该启动子的环境胁迫耐受植物中有效起作用的应激诱导型启动子。 此类启动子来自水稻，由以下DNA（a）或（b）组成：（a）由SEQ ID NO：1或10所示核苷酸序列组成的DNA; 或（b）在严格条件下与由与由SEQ ID NO：1或10所示的核苷酸序列组成的DNA互补的核苷酸序列的DNA杂交并表达应激诱导型启动子活性的DNA。 这种环境胁迫耐受植物已经在其中引入了这种启动子。

    Stress-induced promoter and method of using the same
    4.
    发明授权
    Stress-induced promoter and method of using the same 有权
    应激诱导启动子及其使用方法

    公开(公告)号：US07339050B2

    公开(公告)日：2008-03-04

    申请号：US10550584

    申请日：2004-03-02

    申请人： Kazuko Shinozaki ,  Koji Katsura ,  Yusuke Ito

    发明人： Kazuko Shinozaki ,  Koji Katsura ,  Yusuke Ito

    IPC分类号： A01H1/00 ,  C07H21/04 ,  C12N5/14 ,  C12N15/09

    CPC分类号： C12N15/8237

    摘要： This invention provides a stress-inducible promoter that effectively functions in monocotyledonous plants such as rice, and environmental stress-tolerant plants using the promoter. Such promoter is derived from rice and consists of the following DNA (a) or (b): (a) DNA that consists of the nucleotide sequence as shown in SEQ ID NO: 1 or 10; or (b) DNA that hybridizes under stringent conditions with DNA consisting of a nucleotide sequence that is complementary to the DNA consisting of the nucleotide sequence as shown in SEQ ID NO: 1 or 10 and that expresses stress-inducible promoter activity. Such environmental stress-tolerant plant has had such promoter introduced therein.

    摘要翻译： 本发明提供了在单子叶植物如水稻和使用该启动子的环境胁迫耐受植物中有效起作用的应激诱导型启动子。 此类启动子来自水稻，由以下DNA（a）或（b）组成：（a）由SEQ ID NO：1或10所示核苷酸序列组成的DNA; 或（b）在严格条件下与由与由SEQ ID NO：1或10所示的核苷酸序列组成的DNA互补的核苷酸序列的DNA杂交并表达应激诱导型启动子活性的DNA。 这种环境胁迫耐受植物已经在其中引入了这种启动子。

    Genes encoding plant transcription factors
    5.
    发明授权
    Genes encoding plant transcription factors 有权
    编码植物转录因子的基因

    公开(公告)号：US07138277B2

    公开(公告)日：2006-11-21

    申请号：US10302382

    申请日：2002-11-22

    申请人： Kazuko Shinozaki ,  Yusuke Ito ,  Yoh Sakuma

    发明人： Kazuko Shinozaki ,  Yusuke Ito ,  Yoh Sakuma

    IPC分类号： A01H5/00 ,  C12N15/82

    CPC分类号： C07K14/415 ,  C07H21/04 ,  C12N15/8273

    摘要： Identification of a gene from monocotyledonous plants such as rice, which codes for a transcription factor specific to a stress tolerant gene and provision of a novel environmental stress tolerant plant using the gene. From the rice genome, a gene, which binds to a cis element existing upstream of the gene encoding a stress responsive protein and for a transcription factor to activate the transcription of the gene, is identified. Further, the gene of the transcription factor is used to transform a plant, thereby improving tolerance against environmental stresses such as low temperature, dehydration, and salt stresses.

    摘要翻译： 鉴定来自单子叶植物如水稻的基因，其编码对胁迫耐受基因特异性的转录因子，并提供使用该基因的新型环境胁迫耐受植物。 从水稻基因组中鉴定了与编码应激应答蛋白的基因上游存在的顺式元件和激活基因转录的转录因子结合的基因。 此外，转录因子的基因用于转化植物，从而改善对环境胁迫的耐受性，例如低温，脱水和盐胁迫。

    Genes encoding plant transcription factors
    7.
    发明授权
    Genes encoding plant transcription factors 有权
    编码植物转录因子的基因

    公开(公告)号：US07842854B2

    公开(公告)日：2010-11-30

    申请号：US11453724

    申请日：2006-06-15

    申请人： Kazuko Shinozaki ,  Yusuke Ito ,  Yoh Sakuma

    发明人： Kazuko Shinozaki ,  Yusuke Ito ,  Yoh Sakuma

    IPC分类号： C12N15/29 ,  C12N15/82

    CPC分类号： C07K14/415 ,  C07H21/04 ,  C12N15/8273

    摘要： Identification of a gene from monocotyledonous plants such as rice, which codes for a transcription factor specific to a stress tolerant gene and provision of a novel environmental stress tolerant plant using the gene. From the rice genome, a gene, which binds to a cis element existing upstream of the gene encoding a stress responsive protein and for a transcription factor to activate the transcription of the gene, is identified. Further, the gene of the transcription factor is used to transform a plant, thereby improving tolerance against environmental stresses such as low temperature, dehydration, and salt stresses.

    摘要翻译： 鉴定来自单子叶植物如水稻的基因，其编码对胁迫耐受基因特异性的转录因子，并提供使用该基因的新型环境胁迫耐受植物。 从水稻基因组中鉴定了与编码应激反应蛋白的基因上游存在的顺式元件和激活基因转录的转录因子结合的基因。 此外，转录因子的基因用于转化植物，从而改善对环境胁迫的耐受性，例如低温，脱水和盐胁迫。

    Adiponectin expression-inducing agents and uses thereof
    9.
    发明申请
    Adiponectin expression-inducing agents and uses thereof 失效
    脂联素表达诱导剂及其用途

    公开(公告)号：US20070203061A1

    公开(公告)日：2007-08-30

    申请号：US10594969

    申请日：2005-03-31

    申请人： Takashi Kadowaki ,  Toshimasa Yamauchi ,  Shoko Kitajima ,  Yusuke Ito

    发明人： Takashi Kadowaki ,  Toshimasa Yamauchi ,  Shoko Kitajima ,  Yusuke Ito

    IPC分类号： A61K38/17 ,  C07K14/705 ,  C12Q1/68 ,  G01N33/53 ,  C07H21/04 ,  C12P21/06

    CPC分类号： C07K14/47 ,  A61K38/00 ,  A61K48/00 ,  G01N33/6875 ,  G01N33/74 ,  G01N33/92 ,  G01N2500/10 ,  G01N2800/044

    摘要： The present invention provides adiponectin expression-inducing agents, and therapeutic agents using the same for obesity and obesity-related diseases such as cardiovascular diseases or metabolic diseases, as well as methods of searching for adiponectin expression-inducing agents. KLF9, which can bind to the 32-bp fragment of position −188 to position −157 from the adiponectin expression start site, was demonstrated to enhance adiponectin promoter activity. Therefore, the present invention uses KLF9 as an adiponectin expression-inducing agent, and suggests that KLF9 replenishment therapy is useful for preventing and/or treating obesity or obesity-related diseases including metabolic diseases such as insulin resistance and type II diabetes, and cardiovascular diseases.

    摘要翻译： 本发明提供了脂联素表达诱导剂和使用其的治疗剂用于肥胖症和肥胖相关疾病如心血管疾病或代谢疾病，以及搜索脂联素表达诱导剂的方法。 KLF9可以结合位点-188的32-bp片段，从脂联素表达起始位点到位置-157，证明增强脂连蛋白启动子活性。 因此，本发明使用KLF9作为脂联素表达诱导剂，并且表明KLF9补充疗法可用于预防和/或治疗肥胖症或肥胖相关疾病，包括诸如胰岛素抵抗和II型糖尿病等代谢疾病和心血管疾病 。

    Exhalation gaseous component gauge and a cellular phone equipped with function of measuring gaseous components
    10.
    发明授权
    Exhalation gaseous component gauge and a cellular phone equipped with function of measuring gaseous components 有权
    呼气气分量计和配备测量气体组分功能的蜂窝电话

    公开(公告)号：US06858182B1

    公开(公告)日：2005-02-22

    申请号：US09551349

    申请日：2000-04-18

    申请人： Yusuke Ito ,  Kuniyoshi Koizumi ,  Hiroki Kenmochi

    发明人： Yusuke Ito ,  Kuniyoshi Koizumi ,  Hiroki Kenmochi

    IPC分类号： H04B1/40 ,  G01N33/497 ,  H04M1/02 ,  H04M1/21 ,  H04M1/725 ,  G01N21/00

    CPC分类号： H04M1/0202 ,  G01N33/497 ,  G01N33/4972 ,  H04M1/21 ,  H04M1/72519 ,  H04M2250/12

    摘要： Disclosed is an exhalation gaseous component gauge including, in a palm-sized casing having exhalation taking-in and taking-out slots made on its front and rear sides, a semiconductor gas sensor so placed that the air flowing from one's mouth may pass the sensor, a CPU responsive to the signal from the sensor for determining the quantity of the exhalation gaseous components, and a display for showing the so determined result. The palm-sized casing is so sized and configured as to permit one to have a look at the display while holding the gauge in hand to direct the air from the mouth to the exhalation taking-in slot. Also, disclosed is a cellular phone equipped with an exhalation gaseous component gauge.

    摘要翻译： 公开了一种呼气气体分量计，其包括在手掌大小的壳体中，其具有在其前侧和后侧形成的具有呼气导入和取出槽的半导体气体传感器，使得从嘴的流动的空气可以通过传感器 响应于来自传感器的用于确定呼出气体成分的量的信号的CPU，以及显示如此确定的结果的显示器。 手掌大小的外壳的尺寸和构造尺寸被设计成允许人们在拿着量规的同时观察显示器，以将空气从嘴部引导到呼气插入槽。 此外，公开了配备有呼气气体成分计的蜂窝电话。