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1.发明申请Method for Detecting Disease-Related Marker Using Gastric Mucosal Lavage Fluid 审中-公开使用胃粘膜灌洗液检测疾病相关标记物的方法公开(公告)号：US20100068702A1
公开(公告)日：2010-03-18
申请号：US12227300
申请日：2007-05-15
申请人： Yoshiyuki Watanabe , Yoshiyuki Watanabe , Minoru Toyota , Kohzoh Imai , Yasuhisa Shinomura , Fumio Itoh , Takashi Tokino
发明人： Yoshiyuki Watanabe , Yoshiyuki Watanabe , Minoru Toyota , Kohzoh Imai , Yasuhisa Shinomura , Fumio Itoh , Takashi Tokino
CPC分类号： C12Q1/6806
摘要： The invention relates to a sample containing a gastric mucosa lavage fluid collected from a subject who has received a gastric mucus removal treatment and a method for detecting a disease-related marker using the same. By using the sample of the invention, the disease-related marker can be detected conveniently, less invasively, highly sensitively and highly accurately.
摘要翻译： 本发明涉及含有从接受胃粘液清除处理的受试者收集的胃粘膜灌洗液和使用其的疾病相关标记物检测方法的样品。 通过使用本发明的样品，可以方便地，较少侵入性地，高灵敏度和高度准确地检测疾病相关标志物。
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2.发明授权公开(公告)号：US08841268B2
公开(公告)日：2014-09-23
申请号：US12991335
申请日：2009-05-07
CPC分类号： C12Q1/6886 , A61K31/7105 , A61K31/711 , C07K14/47 , C12N15/113 , C12N2310/141 , C12N2320/10 , C12N2330/10 , C12Q2600/118 , C12Q2600/154 , C12Q2600/178
摘要： The object aims to comprehensively analyze miRNA that undergoes epigenetic silencing in cancer to identify miRNA associated with cancer, elucidate the role of the identified miRNA in cancer, and develop a novel method for detecting cancer and a novel therapeutic agent for cancer both of which relate to the miRNA. Disclosed is a method for detecting cancer in a subject, which comprises detecting methylated CpG in a CpG island located in a promoter region of a microRNA 34b gene and/or a microRNA 34c gene in a biological sample collected from the subject. Also disclosed is a therapeutic agent for cancer, which comprises a nucleic acid encoding a BTG4 gene or BTG4, or comprises a nucleic acid encoding a miR-34b gene and/or an miR-34c gene or miR-34b and/or miR-34c.
摘要翻译： 该目的旨在全面分析在癌症中经历表观遗传学沉默的miRNA，以鉴定与癌症相关的miRNA，阐明鉴定的miRNA在癌症中的作用，并开发出一种检测癌症的新方法和一种用于癌症的新型治疗剂，涉及 miRNA。 公开了一种用于检测受试者中癌症的方法，其包括检测位于从受试者收集的生物样品中的微小RNA 34b基因和/或微小RNA 34c基因的启动子区域中的CpG岛中的甲基化CpG。 还公开了一种癌症治疗剂，其包含编码BTG4基因或BTG4的核酸，或包含编码miR-34b基因和/或miR-34c基因或miR-34b和/或miR-34c的核酸 。
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3.发明申请公开(公告)号：US20110130341A1
公开(公告)日：2011-06-02
申请号：US12991335
申请日：2009-05-07
CPC分类号： C12Q1/6886 , A61K31/7105 , A61K31/711 , C07K14/47 , C12N15/113 , C12N2310/141 , C12N2320/10 , C12N2330/10 , C12Q2600/118 , C12Q2600/154 , C12Q2600/178
摘要： The object aims to comprehensively analyze miRNA that undergoes epigenetic silencing in cancer to identify miRNA associated with cancer, elucidate the role of the identified miRNA in cancer, and develop a novel method for detecting cancer and a novel therapeutic agent for cancer both of which relate to the miRNA. Disclosed is a method for detecting cancer in a subject, which comprises detecting methylated CpG in a CpG island located in a promoter region of a microRNA 34b gene and/or a microRNA 34c gene in a biological sample collected from the subject. Also disclosed is a therapeutic agent for cancer, which comprises a nucleic acid encoding a BTG4 gene or BTG4, or comprises a nucleic acid encoding a miR-34b gene and/or an miR-34c gene or miR-34b and/or miR-34c.
摘要翻译： 该目的旨在全面分析在癌症中经历表观遗传学沉默的miRNA，以鉴定与癌症相关的miRNA，阐明鉴定的miRNA在癌症中的作用，并开发出一种检测癌症的新方法和一种用于癌症的新型治疗剂，涉及 miRNA。 公开了一种用于检测受试者中癌症的方法，其包括检测位于从受试者收集的生物样品中的微小RNA 34b基因和/或微小RNA 34c基因的启动子区域中的CpG岛中的甲基化CpG。 还公开了一种癌症治疗剂，其包含编码BTG4基因或BTG4的核酸，或包含编码miR-34b基因和/或miR-34c基因或miR-34b和/或miR-34c的核酸 。
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4.发明授权公开(公告)号：US09117142B2
公开(公告)日：2015-08-25
申请号：US13995297
申请日：2012-06-07
申请人： Minoru Toyota
发明人： Minoru Toyota
CPC分类号： G06K9/62 , A63F13/12 , A63F2300/552 , A63F2300/6607 , A63F2300/807 , G06T13/80
摘要： A storage unit stores an image file that includes a plurality of dummy image data items indicating predetermined dummy images and movement specifying data specifying the movement of an image, and a plurality of display image data items indicating images of characters. A controller replaces each dummy image data item in the image file with a display image data item to generate a new image file and causes a display unit of a terminal apparatus to display the image file.
摘要翻译： 存储单元存储包括指示预定虚拟图像的多个虚拟图像数据项和指定图像移动的移动指定数据的多个图像数据项和指示图像的多个显示图像数据项的图像文件。 控制器用显示图像数据项替换图像文件中的每个虚拟图像数据项以生成新的图像文件，并使终端装置的显示单元显示图像文件。
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公开(公告)号：US07527315B2
公开(公告)日：2009-05-05
申请号：US11709201
申请日：2007-02-22
申请人： Kazue Sumida , Minoru Toyota , Naomune Moriyama
发明人： Kazue Sumida , Minoru Toyota , Naomune Moriyama
CPC分类号： B60R13/011 , B60N2/757 , B60N2/76 , B60N2002/363 , B60R13/013
摘要： A armrest portion moving forward away from seat backs for allowing an object to be placed thereon is provided at the central portion of the seat backs of a rear row seat, and a movable cushion provided at a central portion of seat cushions in the vehicle width direction. The movable cushion is operative to move upward and forward away from the seat cushions to the location near a front end of the armrest portion. Accordingly, a large-scaled console can be formed at the proper level with the armrest portion and the movable cushion, thereby improving convenience.
摘要翻译： 在后排座椅的座椅靠背的中央部设置有从座椅靠背向前方移动以允许物体放置在其上的扶手部，以及设置在座椅靠垫的车宽方向中央部的可动垫 。 可移动的衬垫可操作以向上和向前移动远离座垫到靠近扶手部分前端的位置。 因此，可以通过扶手部和可动垫在适当的高度上形成大型的控制台，从而提高方便性。
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公开(公告)号：US20050269853A1
公开(公告)日：2005-12-08
申请号：US11126142
申请日：2005-05-11
申请人： Minoru Toyota
发明人： Minoru Toyota
CPC分类号： B60N2/3011 , B60N2/3022 , B60N2/3047 , B60N2/3065 , B60N2/3075 , B60N2/309 , B60N2/36
摘要： The seat device, disposed on the floor panel in the cabin with the instrument panel, comprises the driver seat, the assistant seat and the rear seat, wherein the assistant seat is foldable and movable forward close to the instrument panel to be located in the stored position where the length of the folded seat is made short, the rear seat is foldable and movable forward to be located in the stored position, and the assistant seat in the stored position and the rear seat in the stored position provide the substantially continuous storage space which is formed by back faces of respective seat backs and of the assistant seat and the rear seat. Thus, both the large space and the roomy cabin for passengers can be improved.
摘要翻译： 座椅装置，设置在具有仪表板的机舱内的地板面板上，包括驾驶员座椅，辅助座椅和后座椅，其中辅助座椅是可折叠的并且可靠地靠近仪表板向前移动以被存放在存储的 折叠座椅的长度短的位置，后座椅是可折叠的并且可向前移动以位于存储位置，并且处于存储位置的辅助座椅和处于存储位置的后座椅提供基本上连续的存储空间 其由相应的座椅靠背和辅助座椅和后座椅的背面形成。 因此，可以改善乘客的大空间和宽敞的客舱。
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公开(公告)号：US07487998B2
公开(公告)日：2009-02-10
申请号：US11261475
申请日：2005-10-31
申请人： Minoru Toyota , Akira Ito , Kazue Sumida , Yoshitaka Inoue
发明人： Minoru Toyota , Akira Ito , Kazue Sumida , Yoshitaka Inoue
IPC分类号： B63H11/00
CPC分类号： B60K15/063 , B60N2/3011 , B60N2/305 , B62D25/20
摘要： Disclosed is a fuel tank arrangement structure for a vehicle, which is designed to position a fuel tank 30 under a floor panel 4 forming a floor of a passenger compartment of the vehicle. In the fuel tank arrangement structure, at least a laterally inward portion of the floor panel 4 is formed as a convex floor portion 7 protruding upward from a general surface 8 of the floor panel 4, and at least a laterally inward portion of the fuel tank 30 is formed as a convex fuel-tank portion 30a protruding upward. The convex fuel-tank portion 30a is positioned within a space defined by the convex floor portion 7 while positioning the remaining portion of the fuel tank 30 at a height position lower than the general surface 8 of the floor panel 4, and a seat 9 (10) is positioned inside the passenger compartment and above the convex floor portion 7.
摘要翻译： 公开了一种用于车辆的燃料箱配置结构，其被设计成将燃料箱30定位在形成车辆的乘客室的地板的地板面板4下方。 在燃料箱配置结构中，地板镶板4的至少一个侧向内侧的部分形成为从底板4的一般表面8向上突出的凸起的地板部分7，并且燃料箱的至少一个侧向内部 30形成为向上突出的凸起的燃料箱部分30a。 凸起的燃料箱部分30a位于由凸出的地板部分7限定的空间内，同时将燃料箱30的剩余部分定位在低于地板镶板4的总表面8的高度位置， 10）位于乘客舱内并且在凸起的地板部分7上方。
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公开(公告)号：US06338516B1
公开(公告)日：2002-01-15
申请号：US09257175
申请日：1999-02-25
申请人： Minoru Toyota , Yasuyuki Kimura , Koji Nakao
发明人： Minoru Toyota , Yasuyuki Kimura , Koji Nakao
IPC分类号： B62D900
CPC分类号： B60N2/305 , B60N2/3011 , B60N2/3093 , B62D43/10
摘要： Disclosed herein is a vehicle rear body structure to reduce the amount of the transformation of the vehicle rear body portion for the back row seat in the event of the rear end collision. A pair of the rear wheel houses (51) are formed at the back part of a floor panel. A suspension tower (52) is formed to the rear wheel house (51). The pan (53) is formed nearly in the center part in the traverse direction of the floor panel 1 behind the suspension tower (52). The pan (53) is formed like the plate so as to being opened upward. The bottom of the pan (53) is substantially horizontal. The spare tire (54) is kept substantially horizontal in the pan (53).
摘要翻译： 这里公开了一种在后端碰撞的情况下减少后排座椅的车辆后车身部分的变形量的车辆后车身结构。 一对后轮罩（51）形成在地板面板的后部。 悬挂塔（52）形成在后轮室（51）上。 平底锅（53）几乎形成在悬架塔（52）后面的地板镶板1的横向方向上的中心部分。 锅（53）形成为类似于板向上打开。 平底锅（53）的底部基本上是水平的。 备用轮胎（54）在锅（53）中基本保持水平。
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9.发明申请公开(公告)号：US20130279812A1
公开(公告)日：2013-10-24
申请号：US13995297
申请日：2012-06-07
申请人： Minoru Toyota
发明人： Minoru Toyota
IPC分类号： G06K9/62
CPC分类号： G06K9/62 , A63F13/12 , A63F2300/552 , A63F2300/6607 , A63F2300/807 , G06T13/80
摘要： A storage unit stores an image file that includes a plurality of dummy image data items indicating predetermined dummy images and movement specifying data specifying the movement of an image, and a plurality of display image data items indicating images of characters. A controller replaces each dummy image data item in the image file with a display image data item to generate a new image file and causes a display unit of a terminal apparatus to display the image file.
摘要翻译： 存储单元存储包括指示预定虚拟图像的多个虚拟图像数据项和指定图像移动的移动指定数据的多个图像数据项和指示图像的多个显示图像数据项的图像文件。 控制器用显示图像数据项替换图像文件中的每个虚拟图像数据项以生成新的图像文件，并使终端装置的显示单元显示图像文件。
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公开(公告)号：US20070252401A1
公开(公告)日：2007-11-01
申请号：US11730971
申请日：2007-04-05
申请人： Kazue Sumida , Minoru Toyota , Akira Ito
发明人： Kazue Sumida , Minoru Toyota , Akira Ito
IPC分类号： B60R5/04
CPC分类号： B60R5/04 , B60N2/3009 , B60N2/366
摘要： A seat back is configured to be folded on a seat cushion, a baggage-compartment board is provided in a baggage compartment so as to be supported to move vertically, and there is provided a linkage mechanism to operate the seat back to be folded as the baggage-compartment board moves upward. Accordingly, the seat back can be folded on the seat cushion as the baggage-compartment board moves upward and a difference in level between a back face of the folded seat back and a baggage-compartment floor can be diminished, so operability at a baggage loading can be improved.
摘要翻译： 座椅靠背被配置为折叠在座垫上，行李舱被设置在行李舱中以被支撑以垂直移动，并且设置有连杆机构以操作座椅靠背以被折叠为 行李舱板向上移动。 因此，当行李舱板向上移动时，座椅靠背可以折叠在座垫上，并且可以减小折叠座椅靠背的背面与行李舱室之间的水平差，因此行李装载时的操作性 可以改进。
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