利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

7 条记录 (耗时 0.019 秒)

    METHOD FOR PREPARING SPECIMEN FOR MASS SPECTROMETRY
    2.
    发明申请
    METHOD FOR PREPARING SPECIMEN FOR MASS SPECTROMETRY 审中-公开
    制备样品用于质谱分析的方法

    公开(公告)号：US20090166529A1

    公开(公告)日：2009-07-02

    申请号：US12297160

    申请日：2007-03-23

    申请人： Shuichi Shinma ,  Mitsutoshi Setou ,  Yuki Sugiura ,  Masaru Furuta ,  Takahiro Harada

    发明人： Shuichi Shinma ,  Mitsutoshi Setou ,  Yuki Sugiura ,  Masaru Furuta ,  Takahiro Harada

    IPC分类号： B01D59/44 ,  G01N1/30 ,  G01N1/00

    CPC分类号： G01N35/1002 ,  G01N1/2813 ,  H01J49/0418 ,  Y10T436/25

    摘要： The present invention provides a specimen preparation method for mass spectrometry based on Matrix Assisted Laser Desorption Ionization (MALDI), wherein the method enables to form microcrystals (cocrystals) between matrices and biological molecules (protein and the like) on a biological tissue to generate ions thereof highly efficiently and to perform highly sensitive measurement. Microcrystals are formed on the specimen containing biological molecules, i.e. objects of the measurement, by spraying matrix solution beforehand. Furthermore, dispensation of matrix solution on the microcrystals allows crystals to grow by making preformed micro-matrix crystals as crystal nuclei. Therefore, much finer and more homogeneous crystals (cocrystals) are prepared to enable to perform highly sensitive mass spectrometry based on MALDI. The present invention is a specimen preparation method for mass spectrometry based on matrix assisted laser desorption ionization, wherein the method comprises steps forming microcrystals of matrices on the specimen by spraying matrix solution on the specimen and allowing the microcrystals to grow further by dispensing matrix solutions to the specimen.

    摘要翻译： 本发明提供了一种基于矩阵辅助激光解吸电离（MALDI）的质谱的样品制备方法，其中该方法能够在生物组织上形成基质和生物分子（蛋白质等）之间的微晶（共晶体）以产生离子 高效地进行高灵敏度测定。 通过预先喷涂基质溶液，在含有生物分子即测量对象的样品上形成微晶。 此外，微晶上的基质溶液的分配允许晶体通过使预成型的微晶体晶体作为晶核而生长。 因此，准备更精细和更均匀的晶体（共晶体）以使得能够基于MALDI进行高度敏感的质谱分析。 本发明是一种基于矩阵辅助激光解吸电离的质谱法的样品制备方法，其特征在于，该方法包括通过将样品上的基质溶液喷射到样品上形成基质的微晶的步骤，并通过将基质溶液分配到 标本。

    TRANSFERRING SYSTEM AND TRANSFERRING METHOD
    3.
    发明申请
    TRANSFERRING SYSTEM AND TRANSFERRING METHOD 有权
    传输系统和传输方法

    公开(公告)号：US20130285285A1

    公开(公告)日：2013-10-31

    申请号：US13820078

    申请日：2011-08-31

    申请人： Tatsuya Shimoda ,  Mitsunori Kokubo ,  Yuki Sugiura

    发明人： Tatsuya Shimoda ,  Mitsunori Kokubo ,  Yuki Sugiura

    IPC分类号： B29C59/02

    CPC分类号： B29C59/026 ,  B82Y10/00 ,  B82Y40/00 ,  G03F7/0002 ,  G11B5/855 ,  G11B7/263

    摘要： A transfer system (1) for transferring a fine transfer pattern (M1) formed in a mold (M) to a to-be-molded material (D) provided on a substrate (W) includes a positioning device (3) configured to position the substrate (W) relative to the mold (M) and to bond the mold (M) and the substrate (W) together after the positioning, and a transfer device (5) provided separately from the positioning device (3) and configured to receive the mold (M) and the substrate (W) positioned and bonded together by the positioning device (3), and to cure the to-be-molded material (D) while pressing the mold (M) and the substrate (W) thereby to perform transfer.

    摘要翻译： 用于将形成在模具（M）中的精细转印图案（M1）转印到设置在基板（W）上的待成形材料（D）的转印系统（1）包括定位装置（3） 所述基板（W）相对于所述模具（M），并且在所述定位之后将所述模具（M）和所述基板（W）接合在一起;以及传送装置（5），与所述定位装置（3）分开设置， 通过定位装置（3）接收定位和结合在一起的模具（M）和基板（W），并且在压制模具（M）和基板（W）的同时固化待模制材料（D） 从而进行转移。

    Press forming machine for glass
    5.
    发明申请
    Press forming machine for glass 审中-公开
    玻璃成型机

    公开(公告)号：US20050235699A1

    公开(公告)日：2005-10-27

    申请号：US11113998

    申请日：2005-04-26

    申请人： Satoshi Fukuyama ,  Shigeru Fujiwara ,  Yuki Sugiura

    发明人： Satoshi Fukuyama ,  Shigeru Fujiwara ,  Yuki Sugiura

    IPC分类号： C03B11/00 ,  C03B11/08 ,  C03B11/12 ,  C03B11/16

    CPC分类号： C03B11/16 ,  C03B11/005 ,  C03B11/08 ,  C03B2215/66

    摘要： Inert gas is supplied from a supply source to the interior of a forming chamber through lines and gas supply routes. Variable flow control valves are provided in the middle of the lines and are controlled by a command from a control unit. The variable flow control valves vary pressure or flow rate of the inert gas in accordance with a command value to be sent every moment from the control unit such that the pressure or flow rate gradually reach a target value. According to the present invention, the pressure in the forming chamber is not varied abruptly when supply of the inert gas is stopped or the setting of flow rate thereof is changed. As a result, fluctuation in output of a load cell 8b can be suppressed and high precision of pressing force can be secured.

    摘要翻译： 惰性气体通过管线和气体供应路线从供应源供应到成形室的内部。 可变流量控制阀设置在管路的中间，并由控制单元的指令控制。 可变流量控制阀根据每一时刻从控制单元发送的命令值改变惰性气体的压力或流量，使得压力或流量逐渐达到目标值。 根据本发明，当停止供给惰性气体或其流量的设定改变时，成形室中的压力不会突然变化。 结果，可以抑制测力传感器8b的输出波动，并且可以确保压力的高精度。

    Press forming machine for glass
    6.
    发明授权
    Press forming machine for glass 有权
    玻璃成型机

    公开(公告)号：US07503189B2

    公开(公告)日：2009-03-17

    申请号：US11118358

    申请日：2005-05-02

    申请人： Satoshi Fukuyama ,  Shigeru Fujiwara ,  Yuki Sugiura

    发明人： Satoshi Fukuyama ,  Shigeru Fujiwara ,  Yuki Sugiura

    IPC分类号： G12B1/00

    CPC分类号： C03B11/005 ,  C03B11/125 ,  C03B11/16

    摘要： A load cell is attached between a fixed axis and an upper die assembly and arranged in a forming chamber. For this reason, the load cell is hardly influenced by reduction of pressure in the forming chamber. A cooling plate is arranged between the load cell and the upper die assembly. An interior of the forming chamber is sectioned into two zones by the cooling plate, a flange and an isolating plate. The upper die assembly and a lower die assembly are housed in the lower zone surrounded by a transparent quartz tube. The load cell is housed in the upper zone surrounded by a cooling chamber. Thus, temperature rise of the load cell can be prevented.

    摘要翻译： 测力传感器安装在固定轴线和上模具组件之间并且布置在成形室中。 因此，称重传感器几乎不受成形室内压力的降低的影响。 在测力传感器和上模组件之间布置有冷却板。 成形室的内部由冷却板，凸缘和隔离板分成两个区域。 上模组件和下模组件容纳在由透明石英管围绕的下部区域中。 称重传感器容纳在由冷却室包围的上部区域中。 因此，可以防止测力传感器的温度上升。

    Press forming machine for glass
    7.
    发明申请
    Press forming machine for glass 有权
    玻璃成型机

    公开(公告)号：US20050279137A1

    公开(公告)日：2005-12-22

    申请号：US11118358

    申请日：2005-05-02

    申请人： Satoshi Fukuyama ,  Shigeru Fujiwara ,  Yuki Sugiura

    发明人： Satoshi Fukuyama ,  Shigeru Fujiwara ,  Yuki Sugiura

    IPC分类号： C03B11/00 ,  C03B11/12 ,  C03B11/16

    CPC分类号： C03B11/005 ,  C03B11/125 ,  C03B11/16

    摘要： A load cell is attached between a fixed axis and an upper die assembly and arranged in a forming chamber. For this reason, the load cell is hardly influenced by reduction of pressure in the forming chamber. A cooling plate is arranged between the load cell and the upper die assembly. An interior of the forming chamber is sectioned into two zones by the cooling plate, a flange and an isolating pate. The upper die assembly and a lower die assembly are housed in the lower zone surrounded by a transparent quartz tube. The load cell is housed in the upper zone surrounded by a cooling chamber. Thus, temperature rise of the load cell can be prevented.

    摘要翻译： 测力传感器安装在固定轴线和上模具组件之间并且布置在成形室中。 因此，称重传感器几乎不受成形室内压力的降低的影响。 在压力传感器和上模组件之间布置有冷却板。 成形室的内部通过冷却板，凸缘和隔离板分成两个区域。 上模组件和下模组件容纳在由透明石英管围绕的下部区域中。 称重传感器容纳在由冷却室包围的上部区域中。 因此，可以防止测力传感器的温度上升。