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    T cell apoptosis inducer and method therefore
    1.
    发明授权
    T cell apoptosis inducer and method therefore 有权
    因此T细胞凋亡诱导剂和方法

    公开(公告)号：US09339055B2

    公开(公告)日：2016-05-17

    申请号：US13167483

    申请日：2011-06-23

    申请人： Shigeru Fujiwara ,  Hiroki Kanzato ,  Satoshi Hachimura

    发明人： Shigeru Fujiwara ,  Hiroki Kanzato ,  Satoshi Hachimura

    IPC分类号： C12N1/20 ,  A23L1/30 ,  A61K35/745 ,  A61K35/747 ,  C12R1/225 ,  C12R1/23

    CPC分类号： A23L1/3014 ,  A23L33/135 ,  A23Y2220/05 ,  A23Y2300/55 ,  A61K35/745 ,  A61K35/747 ,  C12N1/20 ,  C12R1/225 ,  C12R1/23

    摘要： An inducer of T cell apoptosis and a health food for inducing T cell apoptosis comprising as an active ingredient of a lactic acid bacterium belonging to the genus Lactobacillus or the genus Bifidobacterium are disclosed. Particularly preferred lactic acid bacteria belonging to the genus Lactobacillus or the genus Bifidobacterium are Lactobacillus acidophilus L-92 (FERM BP-4981), Lactobacillus amylovorus CP1750 (FERM BP-10532), Bifidobacterium catenulatum CP2829 (FERM BP-10533) and Bifidobacterium longum CP760 (FERM BP-10531). The inducer of T cell apoptosis of the invention is useful in the prevention and cure of a disease such as an organ-specific autoimmune disease or type I allergy.

    摘要翻译： 公开了一种T细胞凋亡诱导剂和用于诱导T细胞凋亡的保健食品，其包含属于乳杆菌属或双歧杆菌属的乳酸菌的活性成分。 属于乳杆菌属或双歧杆菌属的特别优选的乳酸菌是嗜酸乳杆菌L-92（FERM BP-4981），淀粉乳杆菌CP1750（FERM BP-10532），连锁双歧杆菌CP2829（FERM BP-10533）和长双歧杆菌CP760 （FERM BP-10531）。 本发明的T细胞凋亡诱导剂可用于预防和治疗诸如器官特异性自身免疫性疾病或I型变态反应的疾病。

    Image forming and erasing apparatus and image forming and erasing method
    2.
    发明授权
    Image forming and erasing apparatus and image forming and erasing method 有权
    图像形成和擦除装置及图像形成和擦除方法

    公开(公告)号：US08879976B2

    公开(公告)日：2014-11-04

    申请号：US13291338

    申请日：2011-11-08

    申请人： Shigeru Fujiwara ,  Satoshi Kinouchi ,  Ryota Saeki ,  Shoko Shimmura ,  Kazutoshi Takahashi ,  Toshihiro Sone ,  Takafumi Amano

    发明人： Shigeru Fujiwara ,  Satoshi Kinouchi ,  Ryota Saeki ,  Shoko Shimmura ,  Kazutoshi Takahashi ,  Toshihiro Sone ,  Takafumi Amano

    IPC分类号： G03G15/20 ,  G03G15/00

    CPC分类号： G03G15/6573 ,  G03G15/6585 ,  G03G15/6591

    摘要： An image forming apparatus according to an embodiment includes: an image erasing section including a first member which has an elastic layer and heats a recording medium having a thermally decolorizable toner image on the toner image side and a second member which erases the toner image by allowing the recording medium in cooperation with the first member; an image forming section which transfers a thermally decolorizable toner image onto the recording medium on which the toner image is erased to form an unfixed toner image; and an image fixing section including a third member which does not have an elastic layer and heats the recording medium on the unfixed toner image side and a fourth member which fixes the unfixed toner image by allowing the recording medium in cooperation with the third member.

    摘要翻译： 根据实施例的图像形成装置包括：图像擦除部分，包括具有弹性层的第一部件，并且在调色剂图像侧加热具有热可脱色调色剂图像的记录介质，以及通过允许调色剂图像来消除调色剂图像的第二部件 记录介质与第一个成员协作; 将热可脱色调色剂图像转印到其上清除调色剂图像的记录介质上以形成未定影的调色剂图像的图像形成部分; 以及图像定影部，其包括不具有弹性层的第三构件，并且对未定影的调色剂像侧加热记录介质;以及第四构件，其通过允许记录介质与第三构件协作来固定未定影的调色剂图像。

    AGENT FOR IMPROVING LIPID METABOLISM
    4.
    发明申请
    AGENT FOR IMPROVING LIPID METABOLISM 有权
    改善脂质代谢的代理

    公开(公告)号：US20130089633A1

    公开(公告)日：2013-04-11

    申请号：US13702742

    申请日：2011-06-08

    申请人： Futoshi Nakamura ,  Yu Ishida ,  Shigeru Fujiwara

    发明人： Futoshi Nakamura ,  Yu Ishida ,  Shigeru Fujiwara

    IPC分类号： A61K35/74

    CPC分类号： A61K35/74 ,  A23D7/0053 ,  A23D7/0056 ,  A23D9/007 ,  A23K10/16 ,  A23L2/52 ,  A23L33/135 ,  A23Y2220/00 ,  A61K35/747

    摘要： This invention provides an effective means or method for improving lipid metabolism, and a means or method for treatment or prevention of diseases or disorders associated with the lipid metabolism disorder. Specifically, this invention relates to an agent for improving the lipid metabolism comprising, as active ingredients, broken cells of a lactic acid bacterium, and to a method for enhancing an effect of a lactic acid bacterium for improving the lipid metabolism comprising a step of breaking the lactic acid bacterium.

    摘要翻译： 本发明提供了改善脂质代谢的有效手段或方法，以及用于治疗或预防与脂质代谢紊乱相关的疾病或病症的方法或方法。 具体地说，本发明涉及一种改善脂质代谢的药剂，其特征在于，其含有作为活性成分的乳酸菌的破碎细胞，以及提高乳酸菌用于改善脂质代谢的效果的方法，其特征在于，包括： 乳酸菌。

    FUSER AND IMAGE FORMING APPARATUS
    6.
    发明申请
    FUSER AND IMAGE FORMING APPARATUS 审中-公开
    FUSER和图像形成装置

    公开(公告)号：US20120183337A1

    公开(公告)日：2012-07-19

    申请号：US13351016

    申请日：2012-01-16

    申请人： Kazutoshi Takahashi ,  Satoshi Kinouchi ,  Shigeru Fujiwara ,  Ryota Saeki ,  Shoko Shimmura ,  Toshihiro Sone ,  Takafumi Amano

    发明人： Kazutoshi Takahashi ,  Satoshi Kinouchi ,  Shigeru Fujiwara ,  Ryota Saeki ,  Shoko Shimmura ,  Toshihiro Sone ,  Takafumi Amano

    IPC分类号： G03G15/20

    CPC分类号： G03G15/206

    摘要： According to one embodiment, a fuser includes a heating roller, an endless belt, and a pressing roller. The heating roller rotates and comes into contact with a toner surface side of a sheet to heat the sheet. The endless belt has hardness lower than the hardness of the heating roller. The pressing roller is an only rotating body provided in a space formed by the endless belt and having an outer diameter smaller than the inner diameter of the endless belt. The pressing roller has hardness lower than the hardness of the heating roller and presses the heating roller via a part of the endless belt.

    摘要翻译： 根据一个实施例，定影器包括加热辊，环形带和加压辊。 加热辊旋转并与片材的调色剂表面侧接触以加热片材。 环形带的硬度低于加热辊的硬度。 加压辊是设置在由环形带形成的空间中并且具有小于环形带的内径的外径的唯一旋转体。 加压辊的硬度低于加热辊的硬度，并通过环形带的一部分按压加热辊。

    RENAL-FUNCTION-AMELIORATING AGENT
    7.
    发明申请
    RENAL-FUNCTION-AMELIORATING AGENT 审中-公开
    肾功能调节剂

    公开(公告)号：US20120177622A1

    公开(公告)日：2012-07-12

    申请号：US13428841

    申请日：2012-03-23

    申请人： Hiromi Suzuki ,  Shigeru Fujiwara

    发明人： Hiromi Suzuki ,  Shigeru Fujiwara

    IPC分类号： A61K35/74 ,  A61P13/12

    CPC分类号： A61K35/74 ,  A61K35/744

    摘要： A method for improving glomerular filtration rate includes administering to a subject in need thereof an agent containing a culture of a bacterium belonging to the genus Bacillus. A method for ameliorating renal failure includes administering to a subject in need thereof an agent with a serum creatinine-lowering effect containing as an active ingredient a culture of a genus Bacillus bacterium. A method for improving glomerular filtration rate or ameliorating renal failure includes administering to a subject in need thereof an agent containing spores of a bacterium belonging to the genus Bacillus.

    摘要翻译： 用于改善肾小球滤过率的方法包括向有需要的受试者施用含有属于芽孢杆菌属的细菌培养物的试剂。 改善肾功能衰竭的方法包括向有需要的受试者施用含有作为活性成分的芽孢杆菌属细菌的培养物的血清肌酐降低作用的药剂。 用于改善肾小球滤过率或改善肾功能衰竭的方法包括向有需要的受试者施用含有属于芽孢杆菌属的细菌孢子的药剂。

    LIPID-METABOLISM-AMELIORATING AGENT
    9.
    发明申请
    LIPID-METABOLISM-AMELIORATING AGENT 审中-公开
    脂肪代谢改性剂

    公开(公告)号：US20100183576A1

    公开(公告)日：2010-07-22

    申请号：US12438242

    申请日：2007-08-14

    申请人： Hiromi Suzuki ,  Shigeru Fujiwara

    发明人： Hiromi Suzuki ,  Shigeru Fujiwara

    IPC分类号： A61K35/74

    CPC分类号： A61K35/74 ,  A61K35/744

    摘要： Pharmaceutical agents and food products which have no side effects, are easy to ingest continuously, and have a serum triglyceride-lowering effect are provided. A lipid metabolism-ameliorating agent and a serum triglyceride-lowering agent, each comprising as an active ingredient a culture of a bacterium belonging to the genus Bacillus, are disclosed. The bacterium belonging to the genus Bacillus is preferably Bacillus subtilis, and more preferably Bacillus subtilis C-3102 (FERN BP-1096). The lipid metabolism-ameliorating agent and the serum triglyceride-lowering agent are useful for treating and preventing diseases such as arteriosclerosis.

    摘要翻译： 没有副作用的药剂和食品容易连续摄取，并具有血清甘油三酯降低效果。 公开了脂质代谢改善剂和血清甘油三酯降低剂，其各自含有属于芽孢杆菌属的细菌的培养物作为活性成分。 属于芽孢杆菌属的细菌优选是枯草芽孢杆菌，更优选枯草芽孢杆菌C-3102（FERN BP-1096）。 脂质代谢改善剂和血清甘油三酯降低剂可用于治疗和预防动脉硬化等疾病。

    Image forming apparatus with cleaning device that does not cause excessive cutting and cleaning method
    10.
    发明授权
    Image forming apparatus with cleaning device that does not cause excessive cutting and cleaning method 有权
    具有清洁装置的图像形成装置，其不会引起过度的切割和清洁方法

    公开(公告)号：US07542695B2

    公开(公告)日：2009-06-02

    申请号：US11447346

    申请日：2006-06-06

    申请人： Shigeru Fujiwara

    发明人： Shigeru Fujiwara

    IPC分类号： G03G15/16

    CPC分类号： G03G21/0029

    摘要： In an image forming apparatus including a cleaning device having a cleaning blade arranged so as to make contact with and separate from a cleaned surface, an occurrence of excessive cutting when the cleaning blade makes contact with the cleaned surface is prevented. The image forming apparatus includes the cleaning blade for making contact with and separating from the cleaned surface and scraping off toner adhered onto the cleaned surface and a regulation unit for regulating a movement of the cleaning blade in the direction of contact with the cleaned surface up to a position where a pressing force to the cleaned surface by the cleaning blade does not exceed a predetermined pressing force.

    摘要翻译： 在包括具有布置成与清洁表面接触并与其分离的清洁刮板的清洁装置的图像形成装置中，防止了当清洁刮板与清洁表面接触时出现过度切割。 图像形成装置包括用于与清洁表面接触并与其分离并清除附着在清洁表面上的调色剂的清洁刮板和用于调节清洁刮板沿与清洁表面接触的方向的运动的调节单元，直到 通过清洁刮板对清洁表面的按压力不超过预定的按压力的位置。