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公开(公告)号：US5870188A
公开(公告)日：1999-02-09
申请号：US715974
申请日：1996-09-19
IPC分类号： G01J3/44
CPC分类号： G01J3/4412
摘要： An excitation beam from a laser is passed through a bandpass filter, and applied to a sample by a collimator lens. An optical adjusting part comprising a camera lens and a converging lens is provided for receiving scattered light from the sample, so that the camera lens receives the scattered light and converts the same to a parallel beam. The converging lens has chromatic aberration, and receives and converges the parallel beam from the camera lens. An inlet slit of a spectroscope is provided as an inlet port on a converging position by the converging lens. This inlet slit is a circular hole having a diameter of about 200 .mu.m. The inlet slit is arranged on a position for converging anti-Stokes-Raman scattered light through the chromatic aberration of the converging lens.
摘要翻译： 来自激光器的激发光束通过带通滤光器，并通过准直透镜施加到样品。 提供包括相机镜头和会聚透镜的光学调节部件，用于接收来自样品的散射光，使得相机镜头接收散射光并将其转换成平行光束。 会聚透镜具有色差，并且从相机透镜接收和收敛平行光束。 分光镜的入口狭缝由会聚透镜设置在聚光位置上的入口。 该入口狭缝是直径约200μm的圆形孔。 入口狭缝布置在通过会聚透镜的色差会聚反斯托克斯 - 拉曼散射光的位置。
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公开(公告)号：US5754289A
公开(公告)日：1998-05-19
申请号：US777282
申请日：1996-12-27
IPC分类号： G01J1/02 , G01J1/42 , G01N21/35 , G01N21/3504 , G01N21/359 , G01N21/65 , G01J3/44
CPC分类号： G01N21/65 , G01N2021/651
摘要： A Raman scattered light measuring apparatus comprises a near infrared semiconductor laser diode as a light source for irradiating a sample with excitation light, while a photoreceiving part for receiving Raman scattered light from the sample comprises a bandpass filter having a vibration wavenumber which is specific to a sample component to be measured as a central wavelength of its transmission region, and a detector consisting of a photodiode of Ge, InAs or InGaAs or a photomultiplier having sensitivity in a near infrared region for detecting Raman scattered light which is transmitted through the bandpass filter.
摘要翻译： 拉曼散射光测量装置包括近红外半导体激光二极管作为用于用激发光照射样品的光源，而用于从样品接收拉曼散射光的光接收部分包括具有振荡波数的带通滤波器，该带通滤波器特定于 待测量的样品成分作为其透射区域的中心波长，以及由Ge，InAs或InGaAs的光电二极管或具有在近红外区域具有灵敏度的光电倍增管的检测器，用于检测通过带通滤波器透射的拉曼散射光。 \！
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公开(公告)号：US5712167A
公开(公告)日：1998-01-27
申请号：US682219
申请日：1996-07-17
CPC分类号： G01N21/65 , Y10T436/173845
摘要： In order to quantitatively measure an Amadori compound by a simple optical method utilizing light scattering, a sample containing an Amadori compound which is stored in a cell is irradiated with excitation light from an He--Ne laser unit so that scattered light from the sample is received and separated into its spectral components for obtaining a light scattering spectrum, and a light scattering peak existing at 820 to 840 cm.sup.-1, 1655 to 1660 cm.sup.-1, 2000 to 2020 cm.sup.-1, 2080 to 2100 cm.sup.-1, 2460 to 2470 cm.sup.-1 or 2530 to 2600 cm.sup.-1 in shift wavenumber with respect to the excitation wavelength in the light scattering spectrum is detected by a detector. The saccharide concentration or the saccharification ratio of the Amadori compound is measured by a calibration curve through the peak intensity or the peak integral value of the light scattering peak.
摘要翻译： 为了通过使用光散射的简单光学方法定量测量阿马多利化合物，将来自He-Ne激光单元的激发光照射存储在电池中的含有Amadori化合物的样品，从而接收来自样品的散射光 并分离成其光谱分量以获得光散射光谱，以及存在于820至840cm -1，1655至1660cm -1，2000至2020cm -1，2080至2100cm -1，2460至 通过检测器检测相对于光散射光谱中的激发波长的2470cm -1或2530〜2600cm -1的位移波数。 阿马多利化合物的糖浓度或糖化率通过校准曲线通过峰光强度或光散射峰的峰值积分值来测量。
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公开(公告)号：US5617205A
公开(公告)日：1997-04-01
申请号：US672027
申请日：1996-06-26
CPC分类号： G01J3/44
摘要： Excitation light from a light source is divided into a sample beam and a correction beam by a half mirror, so that the sample beam is converged on a sample in a sample part by convergent lenses. Condenser lenses are provided in order to converge scattered light from the sample on an inlet slit of a spectroscope, and a holographic notch filter which is set to include the wavelength of the excitation light in its notch region is arranged in order to remove the same wavelength component as the excitation light from the scattered light for selecting target light. The target light and the correction beam are guided onto the same optical axis by a half mirror, to be incident upon a polychrometer through the inlet slit and simultaneously detected. The detected value of the target light is corrected by a simultaneously detected intensity of the correction beam.
摘要翻译： 来自光源的激发光被半反射镜分为采样光束和校正光束，使得样品光束通过会聚透镜会聚在样品部分中的样品上。 提供了冷凝器透镜，以便将来自样品的散射光聚集在分光器的入口狭缝上，并且布置被设置为包括其切口区域中的激发光的波长的全息陷波滤波器，以便去除相同的波长 作为来自用于选择目标光的散射光的激发光的分量。 目标光和校正光束通过半反射镜被引导到相同的光轴上，并通过入口狭缝入射到多个温度计上并同时检测。 通过校正光束的同时检测的强度校正目标光的检测值。
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公开(公告)号：US06887430B1
公开(公告)日：2005-05-03
申请号：US08985816
申请日：1999-03-12
CPC分类号： G01N21/7703 , G01N21/552
摘要： A total reflection cell has a total reflection prism on at least one surface thereof. A mixed solution containing a gold colloid labelled antibody which is adsorbed on a gold colloid is stored in the total reflection cell, and a sample solution containing an antigen causing antigen-antibody reaction with the antibody is added thereto for forming a gold colloid labelled immune complex. A measuring beam is introduced into the total reflection prism from an incident optical system at an angle θ of incidence causing total reflection and an outgoing beam from the total reflection prism is received by a measuring optical system, thereby measuring absorption by the gold colloid labelled immune complex and carrying out qualification and determination of the antigen.
摘要翻译： 全反射单元在其至少一个表面上具有全反射棱镜。 将含有被吸附在金胶体上的金胶体标记抗体的混合溶液储存在全反射池中，向其中加入含抗原抗体与抗体反应的抗原的样品溶液，形成金胶体标记的免疫复合物 。 测量光束从入射光学系统以入射角度θ被引入全反射棱镜，从而引起全反射，并且来自全反射棱镜的输出光束被测量光学系统接收，从而测量金胶体标记的免疫吸收 复杂并进行抗原的鉴定和鉴定。
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公开(公告)号：US5750410A
公开(公告)日：1998-05-12
申请号：US592522
申请日：1996-01-26
IPC分类号： G01N21/55 , G01N33/58 , G01N33/553
CPC分类号： G01N21/77 , G01N21/552 , G01N33/585 , Y10S435/962
摘要： A total reflection cell has a total reflection prism on at least one surface thereof. A mixed solution containing a gold colloid labelled antibody which is adsorbed on a gold colloid is stored in the total reflection cell, and a sample solution containing an antigen causing antigen-antibody reaction with the antibody is added thereto for forming a gold colloid labelled immune complex. A measuring beam is introduced into the total reflection prism from an incident optical system at an angle .theta. of incidence causing total reflection and an outgoing beam from the total reflection prism is received by a measuring optical system, thereby measuring absorption by the gold colloid labelled immune complex and carrying out qualification and determination of the antigen.
摘要翻译： 全反射单元在其至少一个表面上具有全反射棱镜。 将含有被吸附在金胶体上的金胶体标记抗体的混合溶液储存在全反射池中，向其中加入含抗原抗体与抗体反应的抗原的样品溶液，形成金胶体标记的免疫复合物 。 测量光束从入射光学系统以入射角度θ被引入全反射棱镜，从而引起全反射，并且来自全反射棱镜的输出光束被测量光学系统接收，从而测量金胶体标记的免疫吸收 复杂并进行抗原的鉴定和鉴定。
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公开(公告)号：US5741660A
公开(公告)日：1998-04-21
申请号：US594205
申请日：1996-01-30
CPC分类号： G01N21/65 , C12Q1/26 , G01N2021/651
摘要： As to reaction solutions in which the amount of each potassium ferricyanate, glucose oxidase and glucose substrate are set at a constant value while glucose concentrations are varied, intensity changes of peaks at a shift wavenumber of 2081 cm.sup.-1 in light scattering spectra are measured every 10 seconds, the maximum values of the intensity changes of the peaks at the respective glucose concentrations obtained, for obtaining a calibration curve from correlations between the maximum values of the reaction velocities and the glucose concentrations. The calibration curve is employed for carrying out quantitative measurement of an unknown sample.
摘要翻译： 对于在葡萄糖浓度变化时将铁氰化钾，葡萄糖氧化酶和葡萄糖底物的量设定为恒定值的反应溶液，每个测量光散射光谱中在2081cm -1的位移波数处的峰的强度变化 10秒，获得所得各葡萄糖浓度下峰的强度变化的最大值，以从反应速度的最大值与葡萄糖浓度之间的相关性获得校准曲线。 采用校准曲线进行未知样品的定量测量。
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8.发明授权公开(公告)号：US06612986B2
公开(公告)日：2003-09-02
申请号：US09800691
申请日：2001-03-07
IPC分类号： A61B500
CPC分类号： G06F19/3418 , G06F19/00 , G16H10/40 , G16H40/20 , G16H40/63 , Y10S128/904
摘要： A dispersed-type testing/measuring system provides for example a simplified terminal unit to be installed at a patient's home. The dispersed-type testing/measuring system has a central controlling unit 20 and a plurality of terminal units 30 each accessible to the central controlling unit via a communication line 15. Each terminal unit 30 includes a crude data collecting portion 40, and a data transmitting means 45 for sending the data collected by the crude data collecting portion 40 to the central controlling unit 20. The central controlling unit 20 includes a measurement data calculating means 210 for generating measurement data by making calculation on the crude data sent from each terminal unit 30.
摘要翻译： 分散型测试/测量系统例如提供了要安装在患者家中的简化终端单元。分散式测试/测量系统具有中央控制单元20和多个终端单元30，每个终端单元可访问中央控制 每个终端单元30包括原始数据收集部分40和用于将粗原始数据收集部分40收集的数据发送到中央控制单元20的数据发送装置45.中央控制单元20包括 测量数据计算装置210，用于通过对从每个终端单元30发送的原始数据进行计算来产生测量数据。
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公开(公告)号：US06221009B1
公开(公告)日：2001-04-24
申请号：US09214966
申请日：1999-03-09
IPC分类号： A61B500
CPC分类号： G06F19/3418 , G06F19/00 , G16H10/40 , G16H40/20 , G16H40/63 , Y10S128/904
摘要： A dispersed-type testing/measuring system provides for example a simplified terminal unit to be installed at a patient's home. The dispersed-type testing/measuring system has a central controlling unit (20) and a plurality of terminal units 30 each accessible to the central controlling unit via a communication line (15). Each terminal unit (30) includes a crude data collecting portion (40), and a data transmitting means 45 for sending the data collected by the crude data collecting portion 40 to the central controlling unit (20). The central controlling unit 20 includes a measurement data calculating means (210) for generating measurement data by making calculation on the crude data sent from each terminal unit (30).
摘要翻译： 分散式测试/测量系统例如提供了一种要安装在患者家中的简化终端单元。分散式测试/测量系统具有中央控制单元（20）和多个终端单元30，每个终端单元可接入 中央控制单元经由通信线路（15）。 每个终端单元（30）包括原始数据收集部分（40）和用于将由原始数据收集部分40收集的数据发送到中央控制单元（20）的数据发送装置45。 中央控制单元20包括测量数据计算装置，用于通过对从每个终端单元（30）发送的原始数据进行计算来产生测量数据。
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公开(公告)号：US5942754A
公开(公告)日：1999-08-24
申请号：US562814
申请日：1995-11-27
CPC分类号： G01N21/552
摘要： A sample solution is stored in a total reflection cell, and a measuring beam is introduced from an incident optical system to be totally reflected, for measuring a total reflection absorption spectrum. Hydrogen peroxide contained in the sample solution is determined on the basis of absorbance at the position of any absorption peak of the spectrum which is present at 1200 to 1500 cm.sup.-1 or 2600 to 3000 cm.sup.-1. Hydrogen peroxide contained in an aqueous solution can be simply quantitatively analyzed through optical analysis.
摘要翻译： 将样品溶液存储在全反射单元中，并且从入射光学系统引入测量光以被全反射，以测量全反射吸收光谱。 基于在1200至1500cm -1或2600至3000cm -1存在的光谱的任何吸收峰的位置处的吸光度来确定样品溶液中所含的过氧化氢。 含水溶液中的过氧化氢可以通过光学分析简单地定量分析。
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