公开(公告)号：US20200293934A1

公开(公告)日：2020-09-17

申请号：US16818188

申请日：2020-03-13

申请人： Yunong JI ,  Hirotaka UNNO ,  Shigeo HATADA ,  Manabu SEO

发明人： Yunong JI ,  Hirotaka UNNO ,  Shigeo HATADA ,  Manabu SEO

IPC分类号： G06N7/00

摘要： Provided is a technique capable of adequately presenting the product specifications of a material sample even when the concentration distribution of the material is asymmetrical. A material sample according to the present disclosure stores a material having variation according to a probability distribution. As the product specifications of the material sample, the representative value of the probability distribution as well as an interval in which the amount of the material is greater than or equal to a target probability on the probability distribution is displayed.

公开(公告)号：US20190025185A1

公开(公告)日：2019-01-24

申请号：US16041603

申请日：2018-07-20

申请人： Ikuo KATOH ,  Manabu SEO ,  Yunong JI ,  Nobuaki TOYOSHIMA ,  Hiroki SOMADA ,  Ryuya MASHIKO ,  Satoshi IZUMI ,  Takahiko MATSUMOTO ,  Daisuke TAKAGI

发明人： Ikuo KATOH ,  Manabu SEO ,  Yunong JI ,  Nobuaki TOYOSHIMA ,  Hiroki SOMADA ,  Ryuya MASHIKO ,  Satoshi IZUMI ,  Takahiko MATSUMOTO ,  Daisuke TAKAGI

IPC分类号： G01N15/14

摘要： A particle counting apparatus is provided that includes: a droplet discharger configured to discharge a droplet containing at least one luminescent particle capable of emitting light upon receiving light; a light irradiator configured to irradiate the droplet discharged by the droplet discharger with light; at least one light receiver configured to receive light emitted by the at least one luminescent particle irradiated with the light emitted by the light irradiator; and circuitry configured to count luminescent particles contained in the droplet based on the light received by the at least one light receiver, the circuitry being configured to measure a presence or absence of the luminescent particles contained in the droplet; and to measure a number of the luminescent particles contained in the droplet.

公开(公告)号：US20210010072A1

公开(公告)日：2021-01-14

申请号：US16766125

申请日：2018-11-22

申请人： Koei SUZUKI ,  Hirotaka UNNO ,  Manabu SEO ,  Satoshi IZUMI ,  Yusuke OSAKI ,  Yudai KAWASHIMA ,  Michie HASHIMOTO

发明人： Koei SUZUKI ,  Hirotaka UNNO ,  Manabu SEO ,  Satoshi IZUMI ,  Yusuke OSAKI ,  Yudai KAWASHIMA ,  Michie HASHIMOTO

IPC分类号： C12Q1/6851 ,  C12Q1/686

摘要： Provided is a device including: a plurality of wells; a reagent composition located in each of the wells and containing an amplifiable reagent in a specific copy number; and two or more groups into which the wells are divided to have the amplifiable reagent located in the same specific copy number but to be varied in composition of the reagent composition except for the specific copy number. Preferably, composition except for the specific copy number of the amplifiable reagent includes at least any one of primer and amplifying reagent. More preferably, the device includes two or more groups varied in the specific copy number. Yet more preferably, the groups of wells include at least a negative control group in which the specific copy number of the amplifiable reagent is 0, and a group in which the specific copy number of the amplifiable reagent is close to the limit of detection.

公开(公告)号：US20210147906A1

公开(公告)日：2021-05-20

申请号：US16766117

申请日：2018-11-22

申请人： Yusuke OSAKI ,  Satoshi IZUMI ,  Yudai KAWASHIMA ,  Michie HASHIMOTO ,  Manabu SEO ,  Koei SUZUKI ,  Hirotaka UNNO

发明人： Yusuke OSAKI ,  Satoshi IZUMI ,  Yudai KAWASHIMA ,  Michie HASHIMOTO ,  Manabu SEO ,  Koei SUZUKI ,  Hirotaka UNNO

IPC分类号： C12Q1/6806 ,  B01L3/02 ,  C12Q1/689 ,  C12Q1/70

摘要： Provided is a detection determining method used in detection of a testing target in a sample by amplification of the testing target and an amplifiable reagent, wherein the amplifiable reagent is provided in a number of 200 or less, the detection determining method including a determining step of determining that the testing target is present and a detection result is positive when the amplifiable reagent is amplified and the testing target is amplified, and determining that the testing target is absent or at least less than a specific copy number of the amplifiable reagent and a detection result is negative when the amplifiable reagent is amplified and the testing target is not amplified. Also provided are a detection determining device, a detection determining program, and a device used for the detection determining method.

公开(公告)号：US20130235376A1

公开(公告)日：2013-09-12

申请号：US13785436

申请日：2013-03-05

申请人： Naohiro KAMIJO ,  Kohei SHIMBO ,  Yoichi KUBOTA ,  Manabu SEO

发明人： Naohiro KAMIJO ,  Kohei SHIMBO ,  Yoichi KUBOTA ,  Manabu SEO

IPC分类号： G01J3/42

CPC分类号： G01J3/42 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/024 ,  G01J3/0262 ,  G01J3/0297 ,  G01J3/18 ,  G01J3/24 ,  G01J3/2823 ,  G01J3/50 ,  G01J2003/503 ,  G03G15/00 ,  G03G15/5062

摘要： A spectrometer includes a light source to project a light beam to a target object, an optical element including a plurality of apertures through which the light beam reflected by the target object transmits, a diffraction element to form diffracted images from a plurality of light beams having transmitted through the optical element, and a light receiving element to receive the diffracted images formed by the diffraction element and including an optical shield to block a diffracted image other than a certain-order diffracted image.

摘要翻译： 光谱仪包括将光束投射到目标物体的光源，包括由目标物体反射的光束透过的多个孔的光学元件，衍射元件，以从具有多个光束的多个光束形成衍射图像，所述多个光束具有 通过光学元件透射的光接收元件和用于接收由衍射元件形成的衍射图像的光接收元件，并且包括光学屏蔽件以阻挡除一定级衍射图像之外的衍射图像。

公开(公告)号：US20200023328A1

公开(公告)日：2020-01-23

申请号：US16435779

申请日：2019-06-10

申请人： Yuzuru KURAMOCHI ,  Daisuke TAKAGI ,  Satoshi OKANO ,  Takahiko MATSUMOTO ,  Koichi MURAMATSU ,  Satoshi NAKAZAWA ,  Ryuya MASHIKO ,  Manabu SEO ,  Hidekazu YAGINUMA ,  Mayuko MURANO

发明人： Yuzuru KURAMOCHI ,  Daisuke TAKAGI ,  Satoshi OKANO ,  Takahiko MATSUMOTO ,  Koichi MURAMATSU ,  Satoshi NAKAZAWA ,  Ryuya MASHIKO ,  Manabu SEO ,  Hidekazu YAGINUMA ,  Mayuko MURANO

IPC分类号： B01J2/18 ,  B41J2/045 ,  B41J2/025

摘要： A droplet forming device is provided. The droplet forming device includes a liquid holder configured to hold a liquid, a film having a discharge hole, two or more vibration generators configured to vibrate the film, and a driver configured to apply a driving signal to the vibration generators. One or more of the vibration generators are disposed in each region on the film where a polarity of bending moment differs.

公开(公告)号：US20190136304A1

公开(公告)日：2019-05-09

申请号：US16161203

申请日：2018-10-16

申请人： Manabu SEO ,  Satoshi IZUMI ,  Yudai KAWASHIMA

发明人： Manabu SEO ,  Satoshi IZUMI ,  Yudai KAWASHIMA

IPC分类号： C12Q1/6844

摘要： Provided is a detection accuracy identifying method for identifying a detection accuracy for detecting a testing target nucleic acid, the method including identifying a detection accuracy ability of the testing target nucleic acid, using a standard substance containing a known number of nucleic acid molecule and based on a probability at which the known number of nucleic acid molecule is detected.

公开(公告)号：US20130063723A1

公开(公告)日：2013-03-14

申请号：US13559982

申请日：2012-07-27

申请人： Kohei SHIMBO ,  Naohiro KAMIJO ,  Yoichi KUBOTA ,  Manabu SEO

发明人： Kohei SHIMBO ,  Naohiro KAMIJO ,  Yoichi KUBOTA ,  Manabu SEO

IPC分类号： G01J3/18

CPC分类号： G01J3/524 ,  B41F33/00 ,  B41F33/0045 ,  G01J3/04 ,  G01J3/28 ,  G01J3/502 ,  G01N21/86 ,  H04N1/6033 ,  H04N1/6044

摘要： A spectral characteristic acquiring apparatus is provided which includes: an area dividing part; a spectrum separating part; a light receiving part; and a calculating part, wherein the calculating part includes a transformation matrix storing part that stores a transformation matrix used for calculating the spectral characteristic corresponding to electrical signals of a first diffraction pattern group including two or more adjacent diffraction patterns, and a spectral characteristic calculating part that calculates, based on the electrical signals of the first diffraction pattern group and the corresponding transformation matrix, the spectral characteristic at the locations of the image carrying medium corresponding to the apertures of the first diffraction pattern group.

摘要翻译： 提供了一种光谱特征获取装置，包括：区域分割部分; 光谱分离部分; 光接收部; 以及计算部分，其中所述计算部分包括变换矩阵存储部分，所述变换矩阵存储部分存储用于计算与包括两个或更多个相邻衍射图案的第一衍射图形组的电信号相对应的光谱特性的变换矩阵，以及光谱特性计算部分 其基于第一衍射图案组的电信号和相应的变换矩阵计算与第一衍射图案组的孔对应的图像承载介质的位置处的光谱特性。

公开(公告)号：US20180363028A1

公开(公告)日：2018-12-20

申请号：US16007274

申请日：2018-06-13

申请人： Satoshi IZUMI ,  Manabu SEO ,  Takahiko MATSUMOTO ,  Hiroki SOMADA ,  Ryuya MASHIKO ,  Takeshi ORITO ,  Hiroki NAKAE

发明人： Satoshi IZUMI ,  Manabu SEO ,  Takahiko MATSUMOTO ,  Hiroki SOMADA ,  Ryuya MASHIKO ,  Takeshi ORITO ,  Hiroki NAKAE

IPC分类号： C12Q1/6806 ,  C12Q1/686 ,  G01N15/14

摘要： Provided is a method for producing a cell contained base, the method being capable of providing a cell contained base highly accurately controlled in number of nucleic acid molecules contained in a low-concentration nucleic acid standard sample, the method including a liquid droplet discharging step of discharging a cell suspension in the form of a liquid droplet with a liquid droplet discharging unit onto a base including at least one cell contained region; a cell number counting step of counting a number of cells contained in the liquid droplet with a plurality of sensors from two or more directions while the liquid droplet is flying into the cell contained region; and a liquid droplet landing step of landing the liquid droplet in the at least one cell contained region in a manner that a predetermined number of cells are located in the at least one cell contained region.

公开(公告)号：US20170120604A1

公开(公告)日：2017-05-04

申请号：US15335040

申请日：2016-10-26

申请人： Manabu SEO ,  Satoshi NAKAZAWA ,  Yuzuru KURAMOCHI ,  Daisuke TAKAGI ,  Takahiko MATSUMOTO

发明人： Manabu SEO ,  Satoshi NAKAZAWA ,  Yuzuru KURAMOCHI ,  Daisuke TAKAGI ,  Takahiko MATSUMOTO

IPC分类号： B41J2/17 ,  G01N15/06 ,  G01N21/49 ,  B41J2/045

CPC分类号： B41J2/1707 ,  B41J2/14201 ,  B41J2/16579 ,  B41J2002/14354 ,  B41J2202/15 ,  G01N15/06 ,  G01N2015/0693

摘要： A liquid droplet forming apparatus includes a liquid retention unit configured to retain particle suspension liquid in which precipitated particles are suspended; a membrane member, in which a nozzle is formed, configured to discharge the particle suspension liquid retained in the liquid retention unit, as a liquid droplet, by vibration from the nozzle; and a particle state detection unit configured to detect, from a side of the liquid retention unit, a particle state of the precipitated particle around the nozzle in the particle suspension liquid.