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12 条记录 (耗时 0.049 秒)

    Crystals of free (2R, 4R)-monatin and use thereof
    1.
    发明授权
    Crystals of free (2R, 4R)-monatin and use thereof 失效
    游离（2R，4R） - 莫丹汀的晶体及其用途

    公开(公告)号：US07935377B2

    公开(公告)日：2011-05-03

    申请号：US10860018

    申请日：2004-06-04

    申请人： Yusuke Amino ,  Kazuko Hirasawa ,  Kenichi Mori ,  Tadashi Takemoto

    发明人： Yusuke Amino ,  Kazuko Hirasawa ,  Kenichi Mori ,  Tadashi Takemoto

    IPC分类号： A23L1/236 ,  A61K31/40

    CPC分类号： C07D209/20 ,  A23L27/32

    摘要： A crystal of free (2R,4R)-monatin is useful as a sweet substance. The crystals resist absorption of water even under high humidity, are stable and exhibit a high degree of sweetness. Thus, such crystals may used as a sweetening agent or an ingredient thereof, and as an ingredient for imparting sweetness to foods and beverages.

    摘要翻译： 游离（2R，4R） - 莫纳甜的晶体可用作甜味物质。 即使在高湿度下，晶体也能抵抗水分的吸收，稳定，呈现高度的甜度。 因此，这种晶体可以用作甜味剂或其成分，并且作为赋予食品和饮料甜度的成分。

    Process for producing monatin or salt thereof
    4.
    发明授权
    Process for producing monatin or salt thereof 失效
    制备莫纳甜或其盐的方法

    公开(公告)号：US07534898B2

    公开(公告)日：2009-05-19

    申请号：US11627700

    申请日：2007-01-26

    申请人： Yusuke Amino ,  Kazuko Hirasawa

    发明人： Yusuke Amino ,  Kazuko Hirasawa

    IPC分类号： C07D209/20

    CPC分类号： C07D209/18

    摘要： To provide a process for producing monatin where steric configuration of 2-position is in an R configuration or a salt thereof by isomerization of 2-position of monatin where steric configuration of 2-position is in an S configuration.A process for producing monatin where steric configuration of 2-position is in an R configuration or a salt thereof, characterized in that, the process contains a step where isomerization reaction of 2-position of monatin in which steric configuration of 2-position is in an S configuration is carried out in a mixed solvent of water and organic solvent in the presence of an aldehyde and, after that, a step where monatin in which steric configuration of 2-position is in an R configuration or a salt is crystallized.

    摘要翻译： 为了提供通过2-位置为S构型的莫纳甜2-位的异构化来生产2-位的立体构型为R构型的莫纳甜的方法或其盐。 一种制备2-位立体构型为R构型或其盐的莫纳甜的方法，其特征在于，该方法包括其中2-位的立体构型位于莫纳甜2位的异构化反应的步骤 在水和有机溶剂的混合溶剂中在醛的存在下进行S构型，之后，其中2-位的立体构型为R构型的莫纳甜或盐结晶化的步骤。

    Organic amine salts of glutamic acid derivatives and their application
    7.
    发明授权
    Organic amine salts of glutamic acid derivatives and their application 失效
    谷氨酸衍生物的有机胺盐及其应用

    公开(公告)号：US07612214B2

    公开(公告)日：2009-11-03

    申请号：US10992795

    申请日：2004-11-22

    申请人： Yusuke Amino ,  Kazuko Hirasawa

    发明人： Yusuke Amino ,  Kazuko Hirasawa

    IPC分类号： C07D209/18

    CPC分类号： C07D209/20 ,  A23L27/31 ,  A23L27/32

    摘要： The present invention provides an organic amine salt of monatin, or crystal form thereof, and its application as well as a method for resolving the stereoisomers of monatin by forming its salt. The present invention further provides a salt form of monatin that is useful as a sweetening agent or as the active ingredient of a sweetener. The present invention also provides a method for preparing a salt of a particular stereoisomer of monatin with an organic amine by utilizing the difference of crystallinity or solubility of the salt of the stereoisomer of monatin with the organic amine. The present invention also relates to a use of the salt in a method for preparing a metal salt of monatin in which the organic amine is replaced by a metal such as sodium, potassium, or the like.

    摘要翻译： 本发明提供了莫纳甜或其结晶形式的有机胺盐及其应用，以及通过形成其盐来分解莫纳甜的立体异构体的方法。 本发明还提供了可用作甜味剂或作为甜味剂的活性成分的莫纳甜盐形式。 本发明还提供了通过利用莫纳甜的立体异构体的盐与有机胺的结晶度或溶解度的差异来制备莫纳甜的特定立体异构体与有机胺的方法。 本发明还涉及盐在制备莫纳甜金属盐的方法中的用途，其中有机胺被诸如钠，钾等的金属代替。

    Amino acid derivative and sweetening agent
    8.
    发明授权
    Amino acid derivative and sweetening agent 有权
    氨基酸衍生物和甜味剂

    公开(公告)号：US07244462B2

    公开(公告)日：2007-07-17

    申请号：US10981587

    申请日：2004-11-05

    申请人： Yusuke Amino ,  Kazuko Hirasawa

    发明人： Yusuke Amino ,  Kazuko Hirasawa

    IPC分类号： A23L1/236

    CPC分类号： C07D209/18 ,  A23L27/31

    摘要： The present invention provides a novel amino acid derivative, and a salt for thereof. The present invention further provides a sweetening agent and a food or beverage, which contains the novel amino acid derivative of the present invention to increase the sweetness of the same.

    摘要翻译： 本发明提供了一种新的氨基酸衍生物及其盐。 本发明还提供甜味剂和食品或饮料，其含有本发明的新型氨基酸衍生物以增加其甜味。

    Organic amine salts of glutamic acid derivatives and their application
    9.
    发明申请
    Organic amine salts of glutamic acid derivatives and their application 失效
    谷氨酸衍生物的有机胺盐及其应用

    公开(公告)号：US20050137246A1

    公开(公告)日：2005-06-23

    申请号：US10992795

    申请日：2004-11-22

    申请人： Yusuke Amino ,  Kazuko Hirasawa

    发明人： Yusuke Amino ,  Kazuko Hirasawa

    IPC分类号： A23L2/60 ,  A23L27/00 ,  A23L27/30 ,  A61K8/00 ,  A61K8/49 ,  A61K47/22 ,  A61Q11/00 ,  C07B57/00 ,  C07C229/08 ,  C07C229/26 ,  C07C229/36 ,  C07C237/12 ,  C07C279/14 ,  C07D209/20 ,  C07K5/075 ,  A61K31/405 ,  C07D209/18

    CPC分类号： C07D209/20 ,  A23L27/31 ,  A23L27/32

    摘要： The present invention provides an organic amine salt of monatin, or crystal form thereof, and its application as well as a method for resolving the stereoisomers of monatin by forming its salt. The present invention further provides a salt form of monatin that is useful as a sweetening agent or as the active ingredient of a sweetener. The present invention also provides a method for preparing a salt of a particular stereoisomer of monatin with an organic amine by utilizing the difference of crystallinity or solubility of the salt of the stereoisomer of monatin with the organic amine. The present invention also relates to a use of the salt in a method for preparing a metal salt of monatin in which the organic amine is replaced by a metal such as sodium, potassium, or the like.

    摘要翻译： 本发明提供了莫纳甜或其结晶形式的有机胺盐及其应用，以及通过形成其盐来分解莫纳甜的立体异构体的方法。 本发明还提供了可用作甜味剂或作为甜味剂的活性成分的莫纳甜盐形式。 本发明还提供了通过利用莫纳甜的立体异构体的盐与有机胺的结晶度或溶解度的差异来制备莫纳甜的特定立体异构体与有机胺的方法。 本发明还涉及盐在制备莫纳甜金属盐的方法中的用途，其中有机胺被诸如钠，钾等的金属代替。

    PROCESS FOR PRODUCING MONATIN OR SALT THEREOF
    10.
    发明申请
    PROCESS FOR PRODUCING MONATIN OR SALT THEREOF 失效
    生产辛胺或其盐的方法

    公开(公告)号：US20070191464A1

    公开(公告)日：2007-08-16

    申请号：US11627700

    申请日：2007-01-26

    申请人： Yusuke Amino ,  Kazuko Hirasawa

    发明人： Yusuke Amino ,  Kazuko Hirasawa

    IPC分类号： C07D209/18 ,  A61K31/405

    CPC分类号： C07D209/18

    摘要： [Problems] To provide a process for producing monatin where steric configuration of 2-position is in an R configuration or a salt thereof by isomerization of 2-position of monatin where steric configuration of 2-position is in an S configuration. [Means for Resolution] A process for producing monatin where steric configuration of 2-position is in an R configuration or a salt thereof, characterized in that, the process contains a step where isomerization reaction of 2-position of monatin in which steric configuration of 2-position is in an S configuration is carried out in a mixed solvent of water and organic solvent in the presence of an aldehyde and, after that, a step where monatin in which steric configuration of 2-position is in an R configuration or a salt is crystallized.

    摘要翻译： [问题]提供通过2-位置为S构型的莫纳甜2-位的异构化来生产2-位的立体构型为R构型的莫纳甜的方法或其盐。 [解决方法]制造2-位的立体构型为R构型的莫纳甜的方法或其盐，其特征在于，所述方法含有如下步骤：其中monatin的2-位异构化反应， 2-位是S构型，在水和有机溶剂的混合溶剂中，在醛的存在下进行，之后是其中2-位的立体构型为R构型的莫纳甜或 盐结晶。