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公开(公告)号：US09518132B2
公开(公告)日：2016-12-13
申请号：US13883282
申请日：2011-11-09
IPC分类号： C07K16/28 , C07K16/46 , C07K16/00 , C07K16/24 , C07K16/30 , C07K16/40 , G01N33/68 , A61K38/00 , A61K39/00
CPC分类号： C07K16/468 , A61K38/00 , A61K2039/505 , C07K16/00 , C07K16/248 , C07K16/2803 , C07K16/2809 , C07K16/2878 , C07K16/30 , C07K16/40 , C07K16/46 , C07K2317/30 , C07K2317/31 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/66 , C07K2317/73 , G01N33/6854
摘要： Provided herein in certain embodiments are polypeptide complexes capable of binding to an antigen. Pharmaceutical compositions, method of using the polypeptide complexes are also provided.
摘要翻译： 本文在某些实施方案中提供能够结合抗原的多肽复合物。 还提供了药物组合物，使用多肽复合物的方法。
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公开(公告)号：US20130230525A1
公开(公告)日：2013-09-05
申请号：US13883282
申请日：2011-11-09
CPC分类号： C07K16/468 , A61K38/00 , A61K2039/505 , C07K16/00 , C07K16/248 , C07K16/2803 , C07K16/2809 , C07K16/2878 , C07K16/30 , C07K16/40 , C07K16/46 , C07K2317/30 , C07K2317/31 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/66 , C07K2317/73 , G01N33/6854
摘要： Provided herein in certain embodiments are polypeptide complexes capable of binding to an antigen. Pharmaceutical compositions, method of using the polypeptide complexes are also provided.
摘要翻译： 本文在某些实施方案中提供能够结合抗原的多肽复合物。 还提供了药物组合物，使用多肽复合物的方法。
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公开(公告)号：USD1043857S1
公开(公告)日：2024-09-24
申请号：US29934639
申请日：2024-03-27
申请人： Bo Chen
设计人： Bo Chen
摘要： FIG. 1 is a front view of a toy car showing the new design.
FIG. 2 is a rear view thereof.
FIG. 3 is a left side view thereof.
FIG. 4 is a right side view thereof.
FIG. 5 is a top view thereof; and,
FIG. 6 is a bottom view thereof.
The broken lines in the Figures show portions of the toy car that form no part of the claimed design.-
公开(公告)号：USD1013797S1
公开(公告)日：2024-02-06
申请号：US29835672
申请日：2022-04-21
申请人： Bo Chen
设计人： Bo Chen
摘要： FIG. 1 is a front view of a bubble and water gun in accordance with the present invention.
FIG. 2 is a rear view thereof.
FIG. 3 is a left side view thereof.
FIG. 4 is a right side view thereof.
FIG. 5 is a top view thereof; and,
FIG. 6 is a bottom view thereof.
The broken lines show portions of the bubble and water gun that form no part of the claimed design.-
公开(公告)号：USD987947S1
公开(公告)日：2023-06-06
申请号：US29872786
申请日：2023-03-20
申请人： Bo Chen
设计人： Bo Chen
摘要： FIG. 1 is a front, top perspective view of a slipper, showing my new design;
FIG. 2 is a rear, bottom perspective view thereof;
FIG. 3 is a left side elevation view thereof;
FIG. 4 is a right side elevation view thereof;
FIG. 5 is a front elevation view thereof;
FIG. 6 is a rear elevation view thereof;
FIG. 7 is a top plan view thereof;
FIG. 8 is a bottom plan view thereof; and,
FIG. 9 is an enlarged view of detail “9” identified in FIG. 2.
The dashed lines in the figures illustrate portions of the slipper that form no part of the claimed design. The dash dot dash lines in FIGS. 2 and 9 are for the purpose of illustrating the enlarged view indicators and form no part of the claimed design.-
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公开(公告)号：US20180353772A1
公开(公告)日：2018-12-13
申请号：US16002821
申请日：2018-06-07
申请人： Bo Chen , Rafael Armando Sierra
发明人： Bo Chen , Rafael Armando Sierra
IPC分类号： A61N5/06
CPC分类号： A61N5/0616 , A61B18/203 , A61B2018/00023 , A61B2018/00464 , A61N5/0625 , A61N2005/007 , A61N2005/0628 , A61N2005/063 , A61N2005/0643 , A61N2005/0644 , A61N2005/0659 , A61N2005/0663 , A61N2005/067
摘要： In part, the disclosure relates to systems and methods for applying treatment energy, e.g., electromagnetic radiation such as laser radiation, to body areas having bulges and fat deposits and loose skin. Methods and systems disclosed herein are surprisingly effective in generating a desirable temperature profile in a target region (e.g., moderate hyperthermia in a range of about 42 to about 47° C.)). Such systems and methods also provide a dynamic balance of heating (via the application of optical radiation to the skin surface) and cooling, while substantially confining treatment temperatures to the treatment region (e.g., at or below the dermal-hypodermal (D/H) junction). In some aspects, systems and methods are provided that simultaneously reduce fatty deposits (e.g., through lipolysis) and tighten the skin (e.g., through the increased production of collagen) while minimizing patient discomfort and unintended damage, for example, within the epidermis and hypodermis regions adjacent the treatment region.
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