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公开(公告)号：US20140371730A1
公开(公告)日：2014-12-18
申请号：US14340961
申请日：2014-07-25
CPC分类号： A61B18/203 , A61B2018/0047 , A61N5/0616 , A61N2005/067 , H01S3/0092 , H01S3/0627 , H01S3/08018 , H01S3/08054 , H01S3/093 , H01S3/094038 , H01S3/094076 , H01S3/094084 , H01S3/1024 , H01S3/107 , H01S3/1106 , H01S3/1109 , H01S3/1121 , H01S3/1611 , H01S3/1623 , H01S3/1633 , H01S3/1643 , H01S3/1673
摘要： Methods, systems and apparatus are disclosed for delivery of pulsed treatment radiation by employing a pump radiation source generating picosecond pulses at a first wavelength, and a frequency-shifting resonator having a lasing medium and resonant cavity configured to receive the picosecond pulses from the pump source at the first wavelength and to emit radiation at a second wavelength in response thereto, wherein the resonant cavity of the frequency-shifting resonator has a round trip time shorter than the duration of the picosecond pulses generated by the pump radiation source. Methods, systems and apparatus are also disclosed for providing beam uniformity and a sub-harmonic resonator.
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2.发明申请公开(公告)号：US20110152847A1
公开(公告)日：2011-06-23
申请号：US12947310
申请日：2010-11-16
CPC分类号： A61N5/0616 , A61B18/203 , A61B2018/00011 , A61B2018/00452 , A61B2018/0047 , A61B2018/208 , A61B2018/2211 , G02B5/1885
摘要： Methods and apparatus for treatment, such as skin rejuvenation treatment, using non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:YAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a non-uniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the target tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production). A large area of tissue, preferably 7-10 mm in diameter, can be treated simultaneously, while minimizing the risk of burning or other damage to the skin.In one embodiment, the invention uses a fiber bundle to provide a non-uniform energy output beam. In another embodiment, the invention uses a diffractive lens array to produce the non-uniform output beam. A cooling system can also be integrated with the laser treatment system.
摘要翻译： 治疗方法和设备，如皮肤嫩肤治疗，使用不均匀的激光辐射。 激光辐射的高强度部分导致处理区域的选定部分内的胶原蛋白破坏和收缩，而辐射的较低强度部分引起成纤维细胞刺激，导致治疗区域的其它部分的胶原产生。 来自激光源（例如Nd：YAG激光器）的输出光束被耦合到光学系统中，该光学系统修改光束以提供具有不均匀能量分布的大直径光束，该光束由多个高强度区域 被处理梁内的低强度区域包围。 较高强度区域将目标组织的部分热量选择为足以进行第一次处理（例如胶原收缩）的温度，而较低强度区域为第二次处理提供足够的能量（例如刺激的胶原产生）。 可以同时治疗大面积的组织，优选直径为7-10mm，同时最小化对皮肤的燃烧或其它损伤的风险。 在一个实施例中，本发明使用纤维束来提供不均匀的能量输出束。 在另一个实施例中，本发明使用衍射透镜阵列来产生不均匀的输出光束。 冷却系统也可以与激光治疗系统集成。
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公开(公告)号：US07856985B2
公开(公告)日：2010-12-28
申请号：US11347672
申请日：2006-02-03
IPC分类号： A61B19/00
CPC分类号： A61N5/0616 , A61B18/203 , A61B2018/00011 , A61B2018/00452 , A61B2018/0047 , A61B2018/208 , A61B2018/2211 , G02B5/1885
摘要： Methods and apparatus for treatment, such as skin rejuvenation treatment, using non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:YAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a non-uniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the target tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production). A large area of tissue, preferably 7-10 mm in diameter, can be treated simultaneously, while minimizing the risk of burning or other damage to the skin.In one embodiment, the invention uses a fiber bundle to provide a non-uniform energy output beam. In another embodiment, the invention uses a diffractive lens array to produce the non-uniform output beam. A cooling system can also be integrated with the laser treatment system.
摘要翻译： 治疗方法和设备，如皮肤嫩肤治疗，使用不均匀的激光辐射。 激光辐射的高强度部分导致处理区域的选定部分内的胶原蛋白破坏和收缩，而辐射的较低强度部分引起成纤维细胞刺激，导致治疗区域的其它部分的胶原产生。 来自激光源（例如Nd：YAG激光器）的输出光束被耦合到光学系统中，该光学系统修改光束以提供具有不均匀能量分布的大直径光束，该光束由多个高强度区域 被处理梁内的低强度区域包围。 较高强度区域将目标组织的部分热量选择为足以进行第一次处理（例如胶原收缩）的温度，而较低强度区域为第二次处理提供足够的能量（例如刺激的胶原产生）。 可以同时治疗大面积的组织，优选直径为7-10mm，同时最小化对皮肤的燃烧或其它损伤的风险。 在一个实施例中，本发明使用纤维束来提供不均匀的能量输出束。 在另一个实施例中，本发明使用衍射透镜阵列来产生不均匀的输出光束。 冷却系统也可以与激光治疗系统集成。
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公开(公告)号：US20090076489A1
公开(公告)日：2009-03-19
申请号：US12135971
申请日：2008-06-09
IPC分类号： A61B18/22
CPC分类号： A61B18/22 , A61B18/201 , A61B90/361 , A61B90/37 , A61B2017/00084 , A61B2017/00119 , A61B2018/00166 , A61B2018/00464 , A61B2018/00642 , A61B2018/00791 , A61B2218/007
摘要： A laser surgical method is disclosed including: providing a laser surgical device including a handpiece including: an optical delivery component that transmits laser energy from a source to a treatment volume; and an accelerometer configured to provide information indicative of the position of the handpiece. The method includes using the handpiece to transmit laser energy from the source to a plurality of positions within the treatment volume; using the accelerometer, providing information indicative of the position of the handpiece; determining information indicative of an amount of energy delivered at each of the plurality of positions within the treatment volume based on the information indicative of the position of the handpiece, and displaying a graphical representation indicative of the amount of energy delivered at each of the plurality of positions within the treatment volume.
摘要翻译： 公开了一种激光手术方法，包括：提供包括手持件的激光手术装置，其包括：将激光能量从源传递到治疗体积的光学递送部件; 以及加速度计，被配置为提供指示所述手持件的位置的信息。 该方法包括使用手持件将激光能量从源传递到治疗体积内的多个位置; 使用所述加速度计提供指示所述手持件的位置的信息; 基于指示所述手持件的位置的信息，确定指示在所述处理容积内的所述多个位置中的每个位置处的能量的量的信息，以及显示指示在所述多个 处理量内的位置。
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公开(公告)号：US20180353772A1
公开(公告)日：2018-12-13
申请号：US16002821
申请日：2018-06-07
申请人： Bo Chen , Rafael Armando Sierra
发明人： Bo Chen , Rafael Armando Sierra
IPC分类号： A61N5/06
CPC分类号： A61N5/0616 , A61B18/203 , A61B2018/00023 , A61B2018/00464 , A61N5/0625 , A61N2005/007 , A61N2005/0628 , A61N2005/063 , A61N2005/0643 , A61N2005/0644 , A61N2005/0659 , A61N2005/0663 , A61N2005/067
摘要： In part, the disclosure relates to systems and methods for applying treatment energy, e.g., electromagnetic radiation such as laser radiation, to body areas having bulges and fat deposits and loose skin. Methods and systems disclosed herein are surprisingly effective in generating a desirable temperature profile in a target region (e.g., moderate hyperthermia in a range of about 42 to about 47° C.)). Such systems and methods also provide a dynamic balance of heating (via the application of optical radiation to the skin surface) and cooling, while substantially confining treatment temperatures to the treatment region (e.g., at or below the dermal-hypodermal (D/H) junction). In some aspects, systems and methods are provided that simultaneously reduce fatty deposits (e.g., through lipolysis) and tighten the skin (e.g., through the increased production of collagen) while minimizing patient discomfort and unintended damage, for example, within the epidermis and hypodermis regions adjacent the treatment region.
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公开(公告)号：US20090292277A1
公开(公告)日：2009-11-26
申请号：US12534379
申请日：2009-08-03
IPC分类号： A61B18/20
CPC分类号： A61B18/203 , A61B2017/00769 , A61B2018/00452 , A61B2018/0047 , A61N5/0616 , A61N2005/067 , G02F1/0327 , H01S3/00 , H01S3/107 , H01S3/1103 , H01S3/1109 , H01S3/115
摘要： Apparatuses and methods are disclosed for applying laser energy having desired pulse characteristics, including a sufficiently short duration and/or a sufficiently high energy for the photomechanical treatment of skin pigmentations and pigmented lesions, both naturally-occurring (e.g., birthmarks), as well as artificial (e.g., tattoos). The laser energy may be generated with an apparatus having a resonator with the capability of switching between a modelocked pulse operating mode and an amplification operating mode. The operating modes are carried out through the application of a time-dependent bias voltage, having waveforms as described herein, to an electro-optical device (e.g., a Pockels cell) positioned along the optical axis of the resonator.
摘要翻译： 公开了用于施加具有所需脉冲特性的激光能量的装置和方法，包括具有足够短的持续时间和/或足够高的能量用于光自由发生（例如胎记）的皮肤色素沉着和着色损伤的光机械处理，以及 人造（如纹身）。 可以利用具有在锁模脉冲操作模式和放大操作模式之间切换的能力的谐振器的装置来产生激光能量。 操作模式通过将具有如本文所述波形的时间相关偏压施加到沿着谐振器的光轴定位的电光器件（例如，普克尔斯单元）来执行。
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公开(公告)号：US20080031288A1
公开(公告)日：2008-02-07
申请号：US11461812
申请日：2006-08-02
IPC分类号： H01S3/115
CPC分类号： A61B18/203 , A61B2017/00769 , A61B2018/00452 , A61B2018/0047 , A61N5/0616 , A61N2005/067 , G02F1/0327 , H01S3/00 , H01S3/107 , H01S3/1103 , H01S3/1109 , H01S3/115
摘要： Apparatuses and methods are disclosed for applying laser energy having desired pulse characteristics, including a sufficiently short duration and/or a sufficiently high energy for the photomechanical treatment of skin pigmentations and pigmented lesions, both naturally-occurring (e.g., birthmarks), as well as artificial (e.g., tattoos). The laser energy may be generated with an apparatus having a resonator with the capability of switching between a modelocked pulse operating mode and an amplification operating mode. The operating modes are carried out through the application of a time-dependent bias voltage, having waveforms as described herein, to an electro-optical device (e.g., a Pockels cell) positioned along the optical axis of the resonator.
摘要翻译： 公开了用于施加具有所需脉冲特性的激光能量的装置和方法，包括具有足够短的持续时间和/或足够高的能量用于光自由发生（例如胎记）的皮肤色素沉着和着色损伤的光机械处理，以及 人造的（如纹身）。 可以利用具有在锁模脉冲操作模式和放大操作模式之间切换的能力的谐振器的装置来产生激光能量。 操作模式通过将具有如本文所述波形的时间相关偏压施加到沿着谐振器的光轴定位的电光器件（例如，普克尔斯单元）来执行。
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公开(公告)号：US09028536B2
公开(公告)日：2015-05-12
申请号：US12534379
申请日：2009-08-03
CPC分类号： A61B18/203 , A61B2017/00769 , A61B2018/00452 , A61B2018/0047 , A61N5/0616 , A61N2005/067 , G02F1/0327 , H01S3/00 , H01S3/107 , H01S3/1103 , H01S3/1109 , H01S3/115
摘要： Apparatuses and methods are disclosed for applying laser energy having desired pulse characteristics, including a sufficiently short duration and/or a sufficiently high energy for the photomechanical treatment of skin pigmentations and pigmented lesions, both naturally-occurring (e.g., birthmarks), as well as artificial (e.g., tattoos). The laser energy may be generated with an apparatus having a resonator with the capability of switching between a modelocked pulse operating mode and an amplification operating mode. The operating modes are carried out through the application of a time-dependent bias voltage, having waveforms as described herein, to an electro-optical device (e.g., a Pockels cell) positioned along the optical axis of the resonator.
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公开(公告)号：US20130096546A1
公开(公告)日：2013-04-18
申请号：US13508293
申请日：2010-03-05
IPC分类号： A61B18/20
CPC分类号： A61B18/203 , A61B18/22 , A61B2018/00452 , A61B2018/1807 , A61B2018/2211 , A61B2018/2294 , A61N5/06 , A61N5/0616 , A61N2005/0652 , A61N2005/067
摘要： An apparatus is disclosed including: an incoherent light source that generates a treatment beam having a non-uniform energy profile, the non-uniform energy profile being included of regions of relatively high energy per unit area within a substantially uniform background region of relatively low energy per unit area.
摘要翻译： 公开了一种装置，其包括：非相干光源，其产生具有不均匀能量分布的处理束，所述非均匀能量分布包括在相对较低能量的基本上均匀的背景区域内的每单位面积相对较高能量的区域 每单位面积。
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公开(公告)号：US20130035675A1
公开(公告)日：2013-02-07
申请号：US13566306
申请日：2012-08-03
IPC分类号： A61B18/20
CPC分类号： A61B18/203 , A61B2018/0047
摘要： This application provides a consumer device for aesthetic applications, and methods for titrating doses of therapeutic light output from the device in the form of a non-uniform beam, in connection with dermal rejuvenation and cosmetic applications.
摘要翻译： 该应用提供了美学应用的消费者设备，以及用于以与非皮肤复原和化妆品应用相结合的非均匀束的形式滴定从该装置输出的治疗光剂量的方法。
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