公开(公告)号：US20150011348A1

公开(公告)日：2015-01-08

申请号：US14375413

申请日：2013-01-31

申请人： Quantifoil Instruments GmbH

发明人： Andreas Vester

IPC分类号： F16H1/32 ,  B01F9/00 ,  B01F9/10

CPC分类号： F16H1/32 ,  B01F9/0001 ,  B01F9/10 ,  B01F11/0014 ,  B01F2015/00642 ,  F16H1/321 ,  F16H3/003 ,  F16H2001/323 ,  F16H2001/324 ,  F16H2001/327 ,  F16H2200/00 ,  F16H2200/2079

摘要： A mechanism for switching a sample holder (14, 40) accommodating a fluidic sample (38) between an orbital motion mode for sample mixing, particularly for shaking, and a rotary motion mode for sample separation, particularly for centrifuging, wherein the mechanism comprises a gear element (11) being drivable by a drive unit (42) to move selectively in a first direction (A) or in a second direction (B) being inverse to the first direction (A), an orbital motion generator (2 to 5) configured for generating an orbital motion of the sample holder (14, 40) when being operated in the orbital motion mode, a rotary motion generator (2, 4, 5) configured for generating a rotary motion of the sample holder (14, 40) when being operated in the rotary motion mode, and a one-way clutch arrangement (12, 13) configured for selectively coupling the gear element (11) with the orbital motion generator (2 to 5) to transfer a driving force from the gear element (11) to the orbital motion generator (2 to 5) for generating the orbital motion when the gear element (11) is driven in the first direction (A) and to freewheel when the gear element (11) is driven in the second direction (B) or coupling the gear element (11) with the rotary motion generator (2, 4, 5) to transfer a driving force from the gear element (11) to the rotary motion generator (2, 4, 5) for generating the rotary motion when the gear element (11) is driven in the second direction (B) and to freewheel when the gear element (11) is driven in the first direction (A).

摘要翻译： 一种用于在用于样品混合的轨道运动模式，特别是用于摇动的轨道运动模式和用于样品分离的旋转运动模式，特别是用于离心分离的旋转运动模式之间切换容纳流体样品（38）的样品架（14,40）的机构，其中所述机构包括 齿轮元件（11）可由驱动单元（42）驱动，以沿与第一方向（A）相反的第一方向（A）或第二方向（B）有选择地移动;轨道运动发生器（2至5） ），被配置为当以轨道运动模式操作时产生样品保持器（14,40）的轨道运动;旋转运动发生器（2,4,5），其被配置为产生样品保持器（14,40）的旋转运动 ），以及单向离合器装置（12,13），其构造成用于选择性地将所述齿轮元件（11）与所述轨道运动发生器（2至5）联接以从所述齿轮传动驱动力 元件（11）到轨道运动发生器（2到5）f 或当沿第一方向（A）驱动齿轮元件（11）时产生轨道运动，并且当齿轮元件（11）沿第二方向（B）被驱动或者将齿轮元件（11）与 旋转运动发生器（2,4,5），用于当齿轮元件（11）被驱动时将驱动力从齿轮元件（11）传递到旋转运动发生器（2,4,5），用于产生旋转运动 第二方向（B），并且当齿轮元件（11）沿第一方向（A）被驱动时飞轮。

公开(公告)号：US20100031757A1

公开(公告)日：2010-02-11

申请号：US12298508

申请日：2007-04-26

申请人： Olaf Hoyer

发明人： Olaf Hoyer

IPC分类号： G01N1/31

CPC分类号： G01N1/2813 ,  G01N1/312

摘要： A sample handling device (100) for handling a sample, the sample handling device (100) comprising a base part (101), a cover part (102), a first force generating unit (104, 105) adapted to generate an attracting force promoting attraction between the base part (101) and the cover part (102), a second force generating unit (108, 142) adapted to generate a counterforce having at least a component being oriented opposite to the attracting force to promote a motion of the base part (101) and the cover part (102) relative to each other, and a control unit (103) adapted for controlling the second force generating unit (108, 142) for moving the base part (101) and the cover part (102) relative to each other for influencing a sample space (130) between the base part (101) and the cover part (102) for accommodating the sample.

摘要翻译： 一种用于处理样品的样品处理装置（100），所述样品处理装置（100）包括基部（101），盖部（102），适于产生吸引力的第一力产生单元（104,105） 促进基部（101）和盖部（102）之间的吸引力，第二力产生单元（108,142），适于产生至少具有与吸引力相对的部件的反作用力，以促进 基部（101）和盖部（102）相对配置的控制单元（103），以及控制单元（103），用于控制第二力产生单元（108,142），用于使基部（101）和盖部（ 102），用于影响用于容纳样品的基部（101）和盖部（102）之间的样品空间（130）。

公开(公告)号：US20160368003A1

公开(公告)日：2016-12-22

申请号：US14901228

申请日：2014-06-27

申请人： QUANTIFOIL INSTRUMENTS GMBH

发明人： Andreas VESTER ,  Falko SCHULZ

IPC分类号： B04B5/10 ,  G01N35/04 ,  B04B9/08 ,  B04B5/04 ,  B04B13/00 ,  B04B11/04

CPC分类号： B04B5/10 ,  B04B5/0421 ,  B04B9/08 ,  B04B11/04 ,  B04B13/00 ,  G01N35/04 ,  G01N2035/00326 ,  G01N2035/00495 ,  G01N2035/00504 ,  G01N2035/0439 ,  G01N2035/0446 ,  G01N2035/0448

摘要： A sample processing arrangement for processing a fluidic sample, the sample processing arrangement including a sample holder for accommodating the fluidic sample, an apparatus having a rotor mechanism and being configured for selectively operating the sample holder in an orbital motion mode for sample mixing, particularly for shaking, or in a rotary motion mode for sample separation, particularly for centrifuging, a mounting platform having a central portion on which the apparatus and the sample holder are mounted and having a surrounding portion circumferentially surrounding the central portion, and a plurality of module accommodation positions circumferentially distributed in the surrounding portion to surround the rotor mechanism and the sample holder, wherein each of the module accommodation positions is configured for detachably accommodating a selectable one of a plurality of sample processing modules, each being configured for fulfilling an assigned sample processing task, by accommodating the respective sample processing module in the respective one of the module accommodation positions.

摘要翻译： 用于处理流体样品的样品处理装置，所述样品处理装置包括用于容纳流体样品的样品保持器，具有转子机构的装置，并且被配置为用于以轨道运动模式选择性地操作样品保持器用于样品混合，特别是用于 摇动或以用于样品分离的旋转运动模式，特别是用于离心的安装平台，具有中心部分的安装平台，装置和样品架安装在该中心部分上，并且具有围绕中心部分的周围部分，以及多个模块容纳 周向分布在周围部分中以围绕转子机构和样品保持器的位置，其中模块容纳位置中的每一个被配置为可拆卸地容纳多个样本处理模块中的可选择的一个样本处理模块，每个样本处理模块被配置用于实现分配的样本处理任务 ，由ac 在相应的模块收纳位置中对相应的样本处理模块进行商品化。

公开(公告)号：US09126162B2

公开(公告)日：2015-09-08

申请号：US13635901

申请日：2011-03-16

申请人： Olaf Simmat ,  Andreas Vester ,  Patrick Heinrich

发明人： Olaf Simmat ,  Andreas Vester ,  Patrick Heinrich

IPC分类号： B01L9/00 ,  B01F11/00 ,  B01F15/00 ,  B01L7/00 ,  G01N35/02 ,  G01N35/00

CPC分类号： B01F11/0008 ,  B01F15/00733 ,  B01L7/52 ,  B01L9/523 ,  B01L2200/025 ,  G01N35/028 ,  G01N2035/00524

摘要： An apparatus for positioning a functional device, wherein the apparatus has a main body, a carrier element that can be disposed on the main body to receive the functional device, positioning stops, which are mounted displaceably to clamp the functional device, an actuating device which is adapted such that, by actuating the actuating device, the positioning stops can be transferred between an operating state engaging the functional device and an operating state releasing the functional device, and a force transmitting element which is adapted to transmit an actuating force from the actuating device to the positioning stops, wherein the actuating device and the force transmitting element are coupled in such a manner that, in the operating state engaging the functional device, the force transmitting element transmits a functional device force of the functional device to the actuating device in such a manner that the actuating device remains in a rest position with respect to the carrier element, in spite of the action of the transmitted functional device force.

摘要翻译： 一种用于定位功能装置的装置，其中所述装置具有主体，可以设置在所述主体上以容纳所述功能装置的载体元件，可移动地安装以固定所述功能装置的定位止动件;致动装置， 适于使得通过致动所述致动装置，所述定位止动件可以在接合所述功能装置的操作状态和释放所述功能装置的操作状态之间传递，以及力传递元件，其适于从所述致动装置传递致动力 设备到定位止动件，其中致动装置和力传递元件以这样的方式联接，使得在与功能装置接合的操作状态下，力传递元件将功能装置的功能装置力传递到致动装置 使得致动装置相对于载体保持在静止位置 元件，尽管发射的功能装置的力的作用。

公开(公告)号：US20140193312A1

公开(公告)日：2014-07-10

申请号：US14207258

申请日：2014-03-12

申请人： Quantifoil Instruments GmbH

发明人： Olaf Hoyer ,  Andreas Vester ,  Patrick Heinrich

IPC分类号： B01L9/00

CPC分类号： B01L9/523 ,  B01F15/00733 ,  B01L2200/025 ,  B01L2300/0829 ,  G01N35/04 ,  G01N2035/042 ,  G01N2035/0491

摘要： The invention relates to an apparatus for positioning a sample carrier plate, wherein the apparatus comprises a main body for receiving the sample carrier plate, positioning stops which are disposed in opposing first corner regions of the main body and are prestressed for clamping the sample carrier plate and mounted displaceably, an actuating device which is disposed at the main body and is equipped such that by actuating the actuating device the positioning stops can be transferred between an operating state engaging the sample carrier plate and an operating state releasing the sample carrier plate, and comprises a force transmitting element which is equipped to transmit an actuating force from the actuating device to the positioning stops.

摘要翻译： 本发明涉及一种用于定位样品载体板的设备，其中该设备包括用于接收样品载体板的主体，定位止动件，其布置在主体的相对的第一角区域中，并被预应力地夹紧样品载体板 并且可移动地安装有致动装置，该致动装置设置在主体处并且被配置成使得通过致动致动装置，定位止动件可以在接合样品载体板的操作状态和释放样品载体板的操作状态之间传递，以及 包括力传递元件，该力传递元件被配置成将致动力从致动装置传递到定位止动件。

公开(公告)号：US09132428B2

公开(公告)日：2015-09-15

申请号：US13257120

申请日：2010-03-18

申请人： Olaf Simmat ,  Andreas Vester ,  Patrick Heinrich

发明人： Olaf Simmat ,  Andreas Vester ,  Patrick Heinrich

IPC分类号： B01L9/00 ,  G01N35/04 ,  B01F15/00

CPC分类号： B01L9/523 ,  B01F15/00733 ,  B01L2200/025 ,  B01L2300/0829 ,  G01N35/04 ,  G01N2035/042 ,  G01N2035/0491

摘要： The invention relates to an apparatus (100) for positioning a sample carrier plate, wherein the apparatus (100) comprises a main body (102) for receiving the sample carrier plate, positioning stops (106, 108) which are disposed in opposing first corner regions of the main body and are prestressed for clamping the sample carrier plate and mounted displaceably, an actuating device (114) which is disposed in a second corner region of the main body and is equipped such that by actuating the actuating device (114) the positioning stops (106, 108) can be transferred between an operating state engaging the sample carrier plate and an operating state releasing the sample carrier plate, and comprises a force transmitting element (118) which is equipped to transmit an actuating force from the actuating device to the positioning stops.

摘要翻译： 本发明涉及一种用于定位样品载体板的装置（100），其中装置（100）包括用于接收样品载体板的主体（102），定位止动件（106,108），其布置在相对的第一角 主体的区域，并且被预应力用于夹紧样品载体板并可移动地安装;致动装置（114），其布置在主体的第二角区域中，并且被配置成使得通过致动致动装置（114） 定位止动件（106,108）可以在接合样品承载板的操作状态和释放样品承载板的操作状态之间传递，并且包括力传递元件（118），该力传递元件被配置成传递来自致动装置 到定位站。

公开(公告)号：US08323588B2

公开(公告)日：2012-12-04

申请号：US12598760

申请日：2008-05-05

申请人： Olaf Hoyer ,  Leander Dittmann ,  Giso Gessner ,  Andreas Vester

发明人： Olaf Hoyer ,  Leander Dittmann ,  Giso Gessner ,  Andreas Vester

IPC分类号： B01L9/00

CPC分类号： B06B1/16 ,  B01F11/0014

摘要： A sample handling device (100) for handling a sample, the sample handling device (100) comprising a drive shaft (101) being drivable by a drive unit (102), a base plate (103) mounted to follow a motion of the drive shaft (101) when being driven by the drive unit (102), wherein the base plate (103) is configured to receive a sample carrier block (104) mountable to follow a motion of the base plate (103), and a compensation weight (105, 106) mounted asymmetrically on the drive shaft (101) in a manner to at least partially compensate an unbalanced mass of the sample handling device (100) during the motion.

摘要翻译： 一种用于处理样品的样品处理装置（100），所述样品处理装置（100）包括可由驱动单元（102）驱动的驱动轴（101），安装成跟随驱动器的运动的基板（103） 轴（101）由驱动单元（102）驱动时，其中基板（103）构造成接收可安装成跟随基板（103）的运动的样品载体块（104），以及补偿重量 （105,106），其以在运动期间至少部分地补偿样品处理装置（100）的不平衡质量的方式不对称地安装在驱动轴（101）上。

公开(公告)号：US20100218620A1

公开(公告)日：2010-09-02

申请号：US12598760

申请日：2008-05-05

申请人： Olaf Hoyer ,  Leander Dittmann ,  Giso Gessner ,  Andreas Vester

发明人： Olaf Hoyer ,  Leander Dittmann ,  Giso Gessner ,  Andreas Vester

IPC分类号： G01N1/00

CPC分类号： B06B1/16 ,  B01F11/0014

摘要： A sample handling device (100) for handling a sample, the sample handling device (100) comprising a drive shaft (101) being drivable by a drive unit (102), a base plate (103) mounted to follow a motion of the drive shaft (101) when being driven by the drive unit (102), wherein the base plate (103) is configured to receive a sample carrier block (104) mountable to follow a motion of the base plate (103), and a compensation weight (105, 106) mounted asymmetrically on the drive shaft (101) in a manner to at least partially compensate an unbalanced mass of the sample handling device (100) during the motion.

摘要翻译： 一种用于处理样品的样品处理装置（100），所述样品处理装置（100）包括可由驱动单元（102）驱动的驱动轴（101），安装成跟随驱动器的运动的基板（103） 轴（101）由驱动单元（102）驱动时，其中基板（103）构造成接收可安装成跟随基板（103）的运动的样品载体块（104），以及补偿重量 （105,106），其以在运动期间至少部分地补偿样品处理装置（100）的不平衡质量的方式不对称地安装在驱动轴（101）上。

公开(公告)号：US10239063B2

公开(公告)日：2019-03-26

申请号：US14901228

申请日：2014-06-27

申请人： QUANTIFOIL INSTRUMENTS GMBH

发明人： Andreas Vester ,  Falko Schulz

IPC分类号： B04B5/04 ,  B04B5/10 ,  B04B9/08 ,  B04B11/04 ,  B04B13/00 ,  G01N35/00 ,  G01N35/04

摘要： A sample processing arrangement for processing a fluidic sample, the sample processing arrangement including a sample holder for accommodating the fluidic sample, an apparatus having a rotor mechanism and being configured for selectively operating the sample holder in an orbital motion mode for sample mixing, particularly for shaking, or in a rotary motion mode for sample separation, particularly for centrifuging, a mounting platform having a central portion on which the apparatus and the sample holder are mounted and having a surrounding portion circumferentially surrounding the central portion, and a plurality of module accommodation positions circumferentially distributed in the surrounding portion to surround the rotor mechanism and the sample holder, wherein each of the module accommodation positions is configured for detachably accommodating a selectable one of a plurality of sample processing modules, each being configured for fulfilling an assigned sample processing task, by accommodating the respective sample processing module in the respective one of the module accommodation positions.

公开(公告)号：US09371889B2

公开(公告)日：2016-06-21

申请号：US14375413

申请日：2013-01-31

申请人： Quantifoil Instruments GmbH

发明人： Andreas Vester

IPC分类号： F16H1/32 ,  B01F11/00 ,  B01F9/00 ,  B01F9/10 ,  F16H3/00 ,  B01F15/00

CPC分类号： F16H1/32 ,  B01F9/0001 ,  B01F9/10 ,  B01F11/0014 ,  B01F2015/00642 ,  F16H1/321 ,  F16H3/003 ,  F16H2001/323 ,  F16H2001/324 ,  F16H2001/327 ,  F16H2200/00 ,  F16H2200/2079

摘要： A mechanism for switching a sample holder (14, 40) accommodating a fluidic sample (38) between an orbital motion mode for sample mixing, particularly for shaking, and a rotary motion mode for sample separation, particularly for centrifuging, wherein the mechanism comprises a gear element (11) being drivable by a drive unit (42) to move selectively in a first direction (A) or in a second direction (B) being inverse to the first direction (A), an orbital motion generator (2 to 5) configured for generating an orbital motion of the sample holder (14, 40) when being operated in the orbital motion mode, a rotary motion generator (2, 4, 5) configured for generating a rotary motion of the sample holder (14, 40) when being operated in the rotary motion mode, and a one-way clutch arrangement (12, 13) configured for selectively coupling the gear element (11) with the orbital motion generator (2 to 5) to transfer a driving force from the gear element (11) to the orbital motion generator (2 to 5) for generating the orbital motion when the gear element (11) is driven in the first direction (A) and to freewheel when the gear element (11) is driven in the second direction (B) or coupling the gear element (11) with the rotary motion generator (2, 4, 5) to transfer a driving force from the gear element (11) to the rotary motion generator (2, 4, 5) for generating the rotary motion when the gear element (11) is driven in the second direction (B) and to freewheel when the gear element (11) is driven in the first direction (A).

摘要翻译： 一种用于在用于样品混合的轨道运动模式，特别是用于摇动的轨道运动模式和用于样品分离的旋转运动模式，特别是用于离心分离的旋转运动模式之间切换容纳流体样品（38）的样品架（14,40）的机构，其中所述机构包括 齿轮元件（11）可由驱动单元（42）驱动，以沿与第一方向（A）相反的第一方向（A）或第二方向（B）有选择地移动;轨道运动发生器（2至5） ），被配置为当以轨道运动模式操作时产生样品保持器（14,40）的轨道运动;旋转运动发生器（2,4,5），其被配置为产生样品保持器（14,40）的旋转运动 ），以及单向离合器装置（12,13），其构造成用于选择性地将所述齿轮元件（11）与所述轨道运动发生器（2至5）联接以从所述齿轮传动驱动力 元件（11）到轨道运动发生器（2到5）f 或当沿第一方向（A）驱动齿轮元件（11）时产生轨道运动，并且当齿轮元件（11）沿第二方向（B）被驱动或者将齿轮元件（11）与 旋转运动发生器（2,4,5），用于当齿轮元件（11）被驱动时将驱动力从齿轮元件（11）传递到旋转运动发生器（2,4,5），用于产生旋转运动 第二方向（B），并且当齿轮元件（11）沿第一方向（A）被驱动时飞轮。