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公开(公告)号：US09873751B2
公开(公告)日：2018-01-23
申请号：US14541764
申请日：2014-11-14
Applicant: Quick-Med Technologies, Inc.
Inventor： William Toreki , Susan Leander , Gerald M. Olderman
IPC: A61K9/00 , C08F8/00 , A61L15/60 , A61L15/46 , A01N37/02 , A01N59/00 , A61K33/40 , A61K47/48 , A61L15/24 , A61L15/44 , C08L33/08 , C08L33/10
CPC classification number: C08F8/00 , A01N37/02 , A01N59/00 , A61K33/40 , A61K47/58 , A61K2800/56 , A61L15/24 , A61L15/44 , A61L15/46 , A61L15/60 , A61L2300/11 , A61L2300/404 , A61L2300/802 , C08L33/08 , C08L33/10 , Y10T428/1324
Abstract: This invention pertains to a polymeric composition and an antimicrobial composition, each comprising a superabsorbent polymer (SAP), such as used in diapers and sanitary napkins, and peroxide. The superabsorbent material can be made by the process of treating a preformed SAP, such as a crosslinked polyacrylate salt, with a treatment solution comprising hydrogen peroxide dissolved in water, followed by drying. The resulting superabsorbent material has strong antimicrobial activity. Optionally, the treatment solution may also contain a metal salt, including those of zinc, zirconium, and magnesium.
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公开(公告)号：US20170156340A1
公开(公告)日：2017-06-08
申请号：US15413414
申请日：2017-01-23
Applicant: Quick-Med Technologies, Inc.
Inventor： William Toreki , Rustom S. Kanga
CPC classification number: A01N59/16 , A01N59/06 , D06M11/44 , D06M11/45 , D06M11/46 , D06M11/48 , D06M15/00 , D06M23/08 , A01N25/04 , A01N25/10 , A01N25/34 , A01N59/00
Abstract: This invention relates to regenerable antimicrobial coatings with long-lasting efficacy for use in medical applications including implants, medical instruments or devices, and hospital equipment. The same coatings would also have broad utility in the consumer, industrial, and institutional markets. The coating technology would be based on sequestration of hydrogen peroxide (HP) by zinc oxide binders incorporated into the coatings.
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公开(公告)号：US20170156339A1
公开(公告)日：2017-06-08
申请号：US15413258
申请日：2017-01-23
Applicant: Quick-Med Technologies, Inc.
Inventor： William Toreki , Rustom S. Kanga
IPC: A01N59/16 , A01N59/00 , C09D131/04 , C09D7/12 , C09D133/00 , C09D175/04 , A01N25/10 , C09D5/14
CPC classification number: A01N59/16 , A01N25/10 , A01N59/00 , A61L2/00 , A61L2/208 , A61L2/232 , A61L2/238 , A61L9/00 , A61L27/446 , A61L27/54 , A61L27/56 , A61L28/0092 , A61L29/126 , A61L29/146 , A61L31/128 , A61L31/146 , A61L31/16 , A61L2202/24 , A61L2300/11 , A61L2300/404 , A61L2420/04 , C08K2003/2217 , C08K2003/2237 , C08K2003/2244 , C08K2003/2296 , C09D5/14 , C09D7/61 , C09D7/62 , C09D7/67 , C09D11/00 , C09D131/04 , C09D133/00 , C09D175/04
Abstract: This invention relates to regenerable antimicrobial coatings with long-lasting efficacy for use in medical applications including implants, medical instruments or devices, and hospital equipment. The same coatings would also have broad utility in the consumer, industrial, and institutional markets. The coating technology would be based on sequestration of hydrogen peroxide (HP) by zinc oxide binders incorporated into the coatings.
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4.发明申请Regeneration of Antimicrobial Coatings Containing Metal Derivatives Upon Exposure to Vapor-Phase Hydrogen Peroxide 有权暴露于气相过氧化氢时含有金属衍生物的抗微生物涂层的再生公开(公告)号：US20150366214A1
公开(公告)日：2015-12-24
申请号：US14741606
申请日：2015-06-17
Applicant: Quick-Med Technologies, Inc.
Inventor： William Toreki , Rustom Sam Kanga , Bernard Christopher Crampsie , Brendan Barry Wynn
CPC classification number: A61L2/208 , A01N25/10 , A01N25/34 , A01N59/00 , A01N59/16 , A61L2/202 , A61L2/232 , A61L2/238 , A61L2300/102 , A61L2300/11 , B05D3/0446 , B05D3/0453 , B05D5/00 , B05D2201/02
Abstract: This invention relates to regenerable antimicrobial coatings with long-lasting efficacy for use in medical applications including implants, medical instruments or devices, and hospital equipment. The same coatings would also have broad utility in the consumer, industrial, and institutional markets. The coating technology is based on sequestration of hydrogen peroxide (HP) by zinc oxide binders incorporated into the coatings.
Abstract translation: 本发明涉及具有长期有效性的可再生抗微生物涂层，其用于医疗应用，包括植入物，医疗仪器或装置以及医院设备。 相同的涂料在消费者，工业和机构市场也将具有广泛的用途。 涂层技术基于掺入涂层中的氧化锌粘合剂对过氧化氢（HP）的螯合。
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公开(公告)号：US08277827B2
公开(公告)日：2012-10-02
申请号：US12971659
申请日：2010-12-17
Applicant: William Toreki , Albina Mikhaylova , Susan Leander , Bernd Liesenfeld , Gerald M. Olderman
Inventor： William Toreki , Albina Mikhaylova , Susan Leander , Bernd Liesenfeld , Gerald M. Olderman
CPC classification number: D06M11/50 , A61L15/46 , A61L2300/11 , A61L2300/404 , C09D5/14 , C11D3/046 , C11D3/3947 , C11D17/048 , D06M11/155 , D06M11/57 , D06M11/65 , D06M16/00
Abstract: This invention pertains to method for imparting a durable antimicrobial activity to substrates, particularly textiles. An acetate-free metal and peroxide antimicrobial treatment formulation is prepared by adjusting the pH of a mixture of a metal salt in aqueous hydrogen peroxide to about 7.5. The substrate is treated with the composition and dried to afford the treated substrate with antimicrobial activity. Zinc salts, ions, or complexes are preferred.
Abstract translation: 本发明涉及赋予基材，特别是纺织品持久的抗微生物活性的方法。 通过将金属盐在过氧化氢水溶液中的混合物的pH调节至约7.5来制备不含乙酸盐的金属和过氧化物抗微生物处理制剂。 用组合物处理底物并干燥以提供具有抗微生物活性的经处理的底物。 锌盐，离子或络合物是优选的。
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Patent Agency Ranking
6.发明授权Materials with covalently-bonded, nonleachable, polymeric antimicrobial surfaces 有权具有共价键合，不可漂洗，聚合抗菌表面的材料公开(公告)号：US07709694B2
公开(公告)日：2010-05-04
申请号：US09965740
申请日：2001-09-28
Applicant: Christopher D. Batich , Gregory Schultz , Bruce A. Mast , Gerald M. Olderman , David S. Lerner , William Toreki
Inventor： Christopher D. Batich , Gregory Schultz , Bruce A. Mast , Gerald M. Olderman , David S. Lerner , William Toreki
IPC: A61F13/00
CPC classification number: A01N25/34 , A61F13/8405 , A61L15/46 , A61L2300/206 , A61L2300/208 , A61L2300/404 , A61L2300/606 , A01N25/10 , A01N33/12 , A01N47/44
Abstract: This invention relates to methods and compositions for materials having a non-leaching coating that has antimicrobial properties. The coating is applied to substrates such as gauze-type wound dressings. Covalent, non-leaching, non-hydrolyzable bonds are formed between the substrate and the polymer molecules that form the coating. A high concentration of anti-microbial groups on multi-length polymer chains and relatively long average chain lengths, contribute to an absorbent or superabsorbent surface with a high level antimicrobial effect.
Abstract translation: 本发明涉及具有抗菌性能的非浸出涂层的材料的方法和组合物。 将涂层施加到诸如纱布式伤口敷料的基底上。 在底物和形成涂层的聚合物分子之间形成共价，非浸出，不可水解的键。 在多长度聚合物链上具有高浓度的抗微生物群和相当长的平均链长，有助于具有高水平抗微生物效果的吸收剂或超吸收剂表面。
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公开(公告)号：US20090246165A1
公开(公告)日：2009-10-01
申请号：US12064487
申请日：2006-08-22
Applicant: William Toreki , Gerald Olderman
Inventor： William Toreki , Gerald Olderman
Abstract: An alcohol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer.
Abstract translation: 醇溶性，水不溶性消毒剂组合物以及使用该组合物进行消毒并为各种表面（包括皮肤）提供延长的抗微生物性能的方法。 该组合物包含抗微生物聚合物，其能够在不使用含金属或金属的化合物的情况下赋予表面抗微生物性能。 将组合物施加到表面并允许蒸发，留下抗微生物聚合物的涂层。
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8.发明申请METHOD OF ATTACHING AN ANTIMICROBIAL CATIONIC POLYELECTROLYTE TO THE SURFACE OF A SUBSTRATE 有权将抗微生物阳离子聚电解质连接到基材表面的方法公开(公告)号：US20090181157A1
公开(公告)日：2009-07-16
申请号：US11569942
申请日：2006-08-22
Applicant: William Toreki , Bernd Liesenfeld , David Moore , Susan Leander , Christopher Batich
Inventor： William Toreki , Bernd Liesenfeld , David Moore , Susan Leander , Christopher Batich
IPC: B05D3/02
CPC classification number: A01N33/12 , A01N37/12 , A61L2/18 , A61L2/232 , A61L15/46 , A61L2300/208 , A61L2300/216 , A61L2300/404 , A61L2300/80 , A01N25/10 , A01N25/24 , A01N25/34 , A01N2300/00
Abstract: A method of bonding an antimicrobial cationic polyelectrolyte to the surface of a substrate is described, wherein the antimicrobial thus attached to the substrate provides the substrate with antimicrobial properties, and at least a portion of the bonded antimicrobial is substantially non-leachable during normal conditions of use and storage. A method of manufacturing an antimicrobial material is described which comprises exposure of the substrate to a solution of antimicrobial cationic polyelectrolyte, followed by drying the exposed substrate thoroughly to impart a non-leaching property to at least a portion of the antimicrobial cationic polyelectrolytes.
Abstract translation: 描述了将抗微生物阳离子聚电解质结合到基底表面的方法，其中由此附着到基底上的抗微生物赋予底物抗微生物性质，并且至少一部分结合的抗微生物剂在正常条件下基本上不可浸出 使用和存储。 描述了制造抗微生物材料的方法，其包括将基底暴露于抗微生物阳离子聚电解质溶液，然后彻底干燥曝光的底物，以赋予至少一部分抗微生物阳离子聚电解质非浸出性。
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9.发明申请Disinfectant with Durable Activity Based on Alcohol-Soluble Quaternary Ammonium Polymers and Copolymers 失效基于醇溶性季铵盐聚合物和共聚物的耐久活性消毒剂公开(公告)号：US20090117164A1
公开(公告)日：2009-05-07
申请号：US12350784
申请日：2009-01-08
Applicant: William Toreki , Gerald Olderman
Inventor： William Toreki , Gerald Olderman
CPC classification number: A01N47/44 , A01N33/12 , A01N31/02 , A01N31/16 , A01N2300/00
Abstract: An alcohol- or glycol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises at least one alcohol or glycol and an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or a metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer. Alternatively, the composition is incorporated into or within the substrate.
Abstract translation: 醇或二醇可溶的水不溶性消毒剂组合物及其使用方法，用于消毒，并为多种表面（包括皮肤）提供延长的抗微生物性能。 组合物包含至少一种醇或二醇和能够赋予表面抗微生物性能而不使用金属或含金属的化合物的抗微生物聚合物。 将组合物施加到表面并允许蒸发，留下抗微生物聚合物的涂层。 或者，将组合物掺入或在基底内。
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10.发明申请公开(公告)号：US20050033251A1
公开(公告)日：2005-02-10
申请号：US10786959
申请日：2004-02-25
Applicant: William Toreki , Gregory Staab , Gerald Olderman
Inventor： William Toreki , Gregory Staab , Gerald Olderman
CPC classification number: A61L15/46 , A01N25/34 , A61F13/8405 , A61L2300/206 , A61L2300/208 , A61L2300/404 , A61L2300/606 , A01N25/10 , A01N33/12 , A01N47/44
Abstract: This invention relates to methods and compositions for materials having a non-leaching coating that has antimicrobial properties. The coating is applied to substrates such as gauze-type wound dressings, powders and other substrates. Covalent, non-leaching, non-hydrolyzable bonds are formed between the substrate and the polymer molecules that form the coating. A high concentration of anti-microbial groups on multi-length polymer chains and relatively long average chain lengths, contribute to an absorbent or superabsorbent surface with a high level antimicrobial efficacy. Utilization of non-leaching coatings having a plurality of anionic or cationic sites is used according to this invention to bind a plurality of oppositely charged biologically or chemically active compounds, and to release the bound oppositely charged biologically or chemically active compounds from said substrate over a period of time to achieve desired objectives as diverse as improved wound healing to reduction in body odor.
Abstract translation: 本发明涉及具有抗菌性能的非浸出涂层的材料的方法和组合物。 将涂层施加到诸如纱布式伤口敷料，粉末和其它底物的基底上。 在底物和形成涂层的聚合物分子之间形成共价，非浸出，不可水解的键。 在多长度聚合物链上具有高浓度的抗微生物群和相当长的平均链长，有助于具有高水平抗微生物效能的吸收剂或超吸收剂表面。 根据本发明使用具有多个阴离子或阳离子位点的非浸出涂层的使用以结合多个带相反电荷的生物或化学活性化合物，并通过一个或多个化学活性化合物从所述底物上释放结合的带相反电荷的生物或化学活性化合物 一段时间以达到预期的目标，如改善伤口愈合以减少体臭。
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