公开(公告)号：US20240308943A1

公开(公告)日：2024-09-19

申请号：US18039480

申请日：2021-11-29

申请人： Trevor Percival Castor

发明人： Trevor Percival Castor

IPC分类号： C07C37/00 ,  B01D11/02 ,  B01D15/40 ,  B01D15/42 ,  C07C51/48 ,  C07D311/80 ,  G01N30/74

CPC分类号： C07C37/004 ,  B01D11/0203 ,  B01D11/0207 ,  B01D11/0219 ,  B01D11/028 ,  B01D11/0288 ,  B01D11/0292 ,  B01D15/40 ,  B01D15/426 ,  C07C51/48 ,  C07D311/80 ,  G01N30/74 ,  C07C2601/16

摘要： This invention is for improved extracting, separating, and manufacturing pharmaceutical grade CBD and other cannabinoids following current Good Manufacturing Practices (cGMP) of the US FDA for use in clinical trials for central nervous system (CNS) and peripheral nervous system (PNS) disorders such as pain, opioid use disorder, anxiety, epilepsy, nausea and vomiting, Multiple sclerosis and other indications by the National Institute of Health (NIH) and other researchers. This invention first established optimum conditions for the selective SuperFluids™ [supercritical fluids and near-critical fluids with or without polar co-solvents such as alcohols] fractionation of Cannabis sativa to isolate CBD, CBDA, Δ9-THC, Δ9-THCA and other cannabinoids Δ9-THC; then defined SuperFluids™ chromatographic purification conditions for the further purification of CBD, CBDA, Δ9-THC, Δ9-THCA with absolute purities >98.5%. This invention is for methods and apparatus to manufacture pharmaceutical-grade CBD and CBDA (98.5% to 100% with

公开(公告)号：US12053717B2

公开(公告)日：2024-08-06

申请号：US15929263

申请日：2020-04-20

申请人： Gene Pool Technologies, Inc.

发明人： David McGhee

IPC分类号： B01D11/02 ,  C11B1/10 ,  C11B9/02

CPC分类号： B01D11/0207 ,  B01D11/0219 ,  C11B1/10 ,  C11B1/102 ,  C11B1/104 ,  C11B1/108 ,  C11B9/025

摘要： The disclosed embodiments include systems and methods for the solvent extraction of a substance from a material. The disclosed systems include multiple tanks and an extraction chamber in communication with the tanks. Solvent transport is accomplished by heating and/or cooling selected tanks to cause the solvent to be transported between tanks.

公开(公告)号：US12037563B2

公开(公告)日：2024-07-16

申请号：US17238342

申请日：2021-04-23

申请人： Botanex Intellectual Property LLC

发明人： Patrick Neil ,  Dave Baker

IPC分类号： C11B1/10 ,  B01D11/02

CPC分类号： C11B1/10 ,  B01D11/0207 ,  B01D11/0219 ,  B01D11/0257 ,  B01D11/0261 ,  B01D11/0288 ,  B01D11/0296 ,  B01D11/0284

摘要： Some variations provide an automated system for solvent extraction of a feed stock to produce a botanical extract, fats, oils, or other desirable solute, comprising: an extraction reactor; a distillation unit; and a second-stage purge chamber or a second-stage purge process utilizing the extraction reactor itself. The second-stage purge chamber or process receives or holds the solid material along with a heated inert non-condensable gas and/or solvent vapor, to recover residual solvent contained in the solid material. Other variations provide a process comprising: feeding a raw material and a solvent into an extraction reactor; generating dissolved material in rich solvent and extracted solid material; distilling the rich solvent to generate purified product and recovered solvent; conveying the solid material and a heated inert non-condensable gas and/or solvent vapor into a second-stage purge chamber, or holding the solid material in the same vessel, to recover residual solvent; and recovering the purified product.

公开(公告)号：US20240024397A1

公开(公告)日：2024-01-25

申请号：US17870495

申请日：2022-07-21

申请人： Gary Grey

发明人： Gary Grey

IPC分类号： A61K36/185 ,  A61K36/738 ,  B01D11/02 ,  B01D3/14 ,  B01D5/00

CPC分类号： A61K36/185 ,  A61K36/738 ,  B01D11/0296 ,  B01D11/0219 ,  B01D3/143 ,  B01D5/006 ,  A61K2236/10 ,  A61K2236/37 ,  B01D2011/007

摘要： The present technology is directed to methods and processes for optimally extracting and distilling desired natural ingredients from raw natural ingredients, involving pre-soaking the raw natural ingredients in a solvent, boiling the liquid component from the pre-soaking step, allowing the resultant vapor to contact the solid component, and passing the resultant enhanced vapor through a distillation column to obtain a desired product. Any steps of the methods and processes herein can be performed in conjunction with a vacuum or pressurizing device—that is, at an elevated or lowered pressure compared with ambient pressure.

公开(公告)号：US11833447B2

公开(公告)日：2023-12-05

申请号：US17548803

申请日：2021-12-13

申请人： Bizzybee LLC

发明人： Boris David Kogon

IPC分类号： A61L2/00 ,  B01D11/00 ,  B01D11/02 ,  F25B19/00

CPC分类号： B01D11/0219 ,  B01D11/0284 ,  B01D11/0288 ,  B01D11/0292 ,  F25B19/005 ,  B01D2011/007

摘要： This disclosure describes systems, methods, and devices for phytochemical extraction. One example extraction system includes two solvent columns, a material column, and a dewaxing column. The solvent columns store and provide solvent for stripping target chemicals from plant material in the material column. The solvent mixed with target chemicals passes into the dewaxing column, where the target chemicals are separated from waxes and lipids. Cooling is applied to elements of the system by way of an open-loop CO2 refrigeration method. Solvent is moved from the solvent columns to the material column by creating a pressure differential between the two solvent columns.

公开(公告)号：US11801453B2

公开(公告)日：2023-10-31

申请号：US17116249

申请日：2020-12-09

申请人： YAU FU INDUSTRY CO., LTD.

发明人： Ruei-Chang Hsiao

IPC分类号： C11B1/10 ,  C02F1/46 ,  B01D11/02 ,  F26B3/34 ,  C02F1/461 ,  C11B1/16 ,  F22G1/16 ,  F22B29/06 ,  F26B3/06 ,  B01D11/00

CPC分类号： B01D11/0219 ,  C02F1/4618 ,  C11B1/10 ,  C11B1/104 ,  C11B1/16 ,  F22B29/06 ,  F22G1/165 ,  F26B3/06 ,  F26B3/34 ,  B01D2011/007

摘要： A method for cell disruption and extraction of a plant, includes placing plant material on a porous container, placing the porous container into a reaction device, and producing water ion steam of an atmospheric pressure by a water ion generator. The water ion steam infiltrates the porous container and permeates the plant material. The water ion steam penetrate cells of the plant material and breaks the cell wall of the cells, to cause a cell disruption. The residual water ion steam is drained outward from the exhaust pipe of the box.

公开(公告)号：US20190195838A1

公开(公告)日：2019-06-27

申请号：US16070898

申请日：2017-01-19

申请人： Waters Technologies Corporation

发明人： Abhijit Tarafder

IPC分类号： G01N30/06 ,  B01D11/02 ,  B01D15/12 ,  G01N1/40

CPC分类号： G01N30/06 ,  B01D11/0203 ,  B01D11/0219 ,  B01D11/028 ,  B01D11/0288 ,  B01D15/12 ,  B01D17/12 ,  G01N1/4055 ,  G01N30/02 ,  G01N30/08 ,  G01N30/20 ,  G01N30/32 ,  G01N30/34 ,  G01N35/1097 ,  G01N2001/4061 ,  G01N2030/009 ,  G01N2030/062 ,  G01N2030/085 ,  G01N2030/328 ,  G01N2030/347 ,  G01N2035/0444

摘要： In a chromatography system, including within the system an extraction vessel which receives a mixture of mobile phase and co-solvent and provides a mixture of mobile phase and co-solvent with sample to a chromatography column to increase sample concentration within the mixture. In addition, adding a reservoir to the chromatography system to form an extraction-pressurization system, wherein the mixture with sample may be collected in the reservoir and may diffuse and equilibrate to an approximately uniform sample concentration before being provided to the chromatography column. Also in addition, providing a plurality of extraction-pressurization systems to allow near-simultaneous extraction of sample and loading of the column, or concurrent extraction and loading by the plurality of extraction-pressurization systems.

公开(公告)号：US20190192992A1

公开(公告)日：2019-06-27

申请号：US16291705

申请日：2019-03-04

申请人： Nextleaf Solutions Ltd.

发明人： Ryan Delmoral Ko

IPC分类号： B01D11/02 ,  B01D46/00

CPC分类号： B01D11/0219 ,  A61K2236/31 ,  A61K2236/333 ,  A61K2236/37 ,  A61K2236/39 ,  B01D11/02 ,  B01D11/0207 ,  B01D11/0284 ,  B01D11/0288 ,  B01D11/0296 ,  B01D11/0492 ,  B01D24/007 ,  B01D29/56 ,  B01D35/18 ,  B01D46/0006 ,  B01D2011/007

摘要： A series of vertically oriented filters of decreasing pore size is sealed from the atmosphere. Pressurized gas is used to force the liquid to be filtered through the filters. The filter stages are thermally insulated from ambient temperatures in order to maintain the liquid passing through at a reduced temperature. Each filter stage has a removable lid, which provides convenient access for replacing the filter cartridge, allowing it to be changed without disturbing the thermally insulated sidewalls of the filter stage.

公开(公告)号：US20180257048A1

公开(公告)日：2018-09-13

申请号：US15915602

申请日：2018-03-08

申请人： Waters Technologies Corporation

发明人： Michael Webster ,  David Sauers ,  Curt White ,  Steven Stricko

IPC分类号： B01F5/06 ,  B01D11/02 ,  C11B1/10

CPC分类号： B01F5/0691 ,  B01D11/0203 ,  B01D11/0219 ,  B01D11/0284 ,  B01F2215/0036 ,  C11B1/104

摘要： Exemplary embodiments are directed to a diffuser assembly configured to be disposed in an extraction path of an extracting solvent in an extraction vessel. The diffuser assembly includes a housing configured to be disposed within the extraction vessel, the housing including an inner surface and an outer surface. The diffuser assembly includes an inlet structure disposed within the housing. The diffuser assembly includes an outlet structure disposed within the housing and spaced from the inlet structure to form a mixing chamber between the inlet structure and the outlet structure. The inlet structure and the outlet structure each have a porosity configured for passage of the extracting solvent therethrough. Passage of the extracting solvent through the inlet structure, the mixing chamber, and the outlet structure redistributes flow of the extracting solvent along the extraction path.

公开(公告)号：US20180036650A1

公开(公告)日：2018-02-08

申请号：US15788185

申请日：2017-10-19

申请人： ESSENTIAL INNOVATIONS, LLC

发明人： Casey STEELE

IPC分类号： B01D11/02 ,  C11B9/02 ,  C11B1/10

CPC分类号： B01D11/0219 ,  B01D11/0207 ,  B01D11/0288 ,  B01D11/0292 ,  C11B1/10 ,  C11B9/02

摘要： A system and method of extracting essential oils from plant material through the use of a low pressure alcohol-based closed system that includes a solvent chamber connected to a material column that in turn is connected to a recovery chamber. Plant material in the material column and the solvent in the solvent chamber are cooled using a cooling liquid, such as nitrogen. A vacuum pump connected to the recovery chamber creates a vacuum in the recovery chamber to draw the cooled solvent through the cooled plant material and extract essential oils, which are collected in the recovery chamber.