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    ACTUATOR ELEMENTS FOR MICROFLUIDICS, RESPONSIVE TO MULTIPLE STIMULI
    1.
    发明申请
    ACTUATOR ELEMENTS FOR MICROFLUIDICS, RESPONSIVE TO MULTIPLE STIMULI 审中-公开
    微生物执行器元件，响应多个STIMULI

    公开(公告)号：US20090165877A1

    公开(公告)日：2009-07-02

    申请号：US12278417

    申请日：2007-02-01

    Applicant: Jacob Marinus Jan Den Toonder ,  Dirk Jan Broer ,  Auke Ronald Van Dijken

    Inventor： Jacob Marinus Jan Den Toonder ,  Dirk Jan Broer ,  Auke Ronald Van Dijken

    IPC: B81B7/02 ,  F15C3/00 ,  B81C1/00

    CPC classification number: F04D33/00 ,  B01F13/0059 ,  B01F13/0091 ,  B01F13/0827 ,  B01L3/502707 ,  B01L3/502746 ,  B01L2300/0858 ,  B01L2300/0887 ,  B01L2400/0484 ,  F04B19/006 ,  Y10T29/49229 ,  Y10T29/494 ,  Y10T137/2191 ,  Y10T137/2213

    Abstract: A micro-fluidic system comprises at least one micro-channel having a wall (14), a plurality of ciliary actuator elements (71) attached to said wall (14), said ciliary actuator elements (71) having an original shape when not subjected to a liquid, and means for applying stimuli to said plurality of ciliary actuator elements (71) so as to cause a change in their shape from an initial shape to an end shape. The ciliary actuator elements (71) are adapted to respond to the presence of a particular liquid by changing their original shape into the initial shape. The response to the presence of the particular liquid may be a curving of the original shape of the ciliary actuator element. Application of stimuli to the plurality of ciliary actuator elements provides a way to locally manipulate the flow of complex fluids in a micro-fluidic system.

    Abstract translation: 微流体系统包括至少一个具有壁（14）的微通道，附接到所述壁（14）的多个纤毛致动器元件（71），所述纤维致动器元件（71）当不受影响时具有原始形状 以及用于将刺激施加到所述多个纤毛致动器元件（71）以使其形状从初始形状改变为端部形状的装置。 纤毛致动器元件（71）适于通过将其原始形状改变为初始形状来响应特定液体的存在。 对特定液体的存在的响应可以是纤毛致动器元件的原始形状的弯曲。 刺激对多个纤毛致动器元件的应用提供了一种在微流体系统中局部地操纵复杂流体的流动的方式。

    MICRO-FLUIDIC SYSTEM
    2.
    发明申请
    MICRO-FLUIDIC SYSTEM 审中-公开
    微流体系统

    公开(公告)号：US20100183456A1

    公开(公告)日：2010-07-22

    申请号：US12376641

    申请日：2007-08-08

    Applicant: Jacob Marinus Jan Den Toonder ,  Lucas Van Rijsewijk ,  Dirk Jan Broer

    Inventor： Jacob Marinus Jan Den Toonder ,  Lucas Van Rijsewijk ,  Dirk Jan Broer

    IPC: F04B35/04 ,  B23P15/00

    CPC classification number: F04D33/00 ,  B01F13/0059 ,  B01F13/0091 ,  B01F13/0827 ,  B01L3/502707 ,  B01L3/502746 ,  B01L2300/0819 ,  B01L2300/089 ,  B01L2400/0415 ,  B01L2400/0484 ,  F04B19/006 ,  Y10T29/49236

    Abstract: The present invention provides a micro-fluidic system, a method for manufacturing a micro-fluidic system and a method for controlling or manipulating a fluid flow through micro-channels of such a micro-fluidic system. The inner side of the wall of the micro-channel is provided with actuator elements. These actuator elements have a shape, an orientation and a geometry that includes a varying cross sectional area along a longitudinal axis. The varying cross sectional area includes one or more openings along the longitudinal axis of the actuator element. The actuator elements can change in shape and orientation as a response to an external stimulus. Through this change of the shape and orientation, the flow of a fluid through a micro-channel may be controlled and manipulated.

    Abstract translation: 本发明提供微流体系统，微流体系统的制造方法以及控制或操纵通过这种微流体系统的微通道的流体流动的方法。 微通道壁的内侧设有致动元件。 这些致动器元件具有包括沿着纵向轴线的变化的横截面积的形状，取向和几何形状。 变化的横截面区域包括沿着致动器元件的纵向轴线的一个或多个开口。 致动器元件可以作为对外部刺激的响应而在形状和方向上改变。 通过形状和取向的这种变化，可以控制和操纵通过微通道的流体的流动。

    MICROFLUIDIC DEVICE WITH INTEGRATED STIRRING STRUCTURE AND MANUFACTURING METHOD THEREOF
    5.
    发明申请
    MICROFLUIDIC DEVICE WITH INTEGRATED STIRRING STRUCTURE AND MANUFACTURING METHOD THEREOF 有权
    具有集成式搅拌结构的微流体装置及其制造方法

    公开(公告)号：US20140308738A1

    公开(公告)日：2014-10-16

    申请号：US14250098

    申请日：2014-04-10

    Applicant: STMicroelectronics S.r.l.

    Inventor： Sabrina Conoci ,  Paolo Ferrari

    IPC: B01L3/00 ,  C12M1/06

    CPC classification number: B81C1/00198 ,  B01F11/0082 ,  B01F13/0059 ,  B01F13/0091 ,  B01L3/502707 ,  B01L3/50273 ,  B01L2200/12 ,  B01L2300/06 ,  B81C1/00166 ,  B81C1/00182 ,  C12M27/02 ,  Y10T29/49009

    Abstract: A microfluidic device, comprising: a semiconductor body, having a first side and a second side, opposite to one another in a first direction; and at least one well, configured for containing a fluid, extending in the semiconductor body starting from the first side and being delimited at the bottom by a bottom surface. The microfluidic device further comprises a stirring structure integrated in the well at the bottom surface, the stirring structure including a first stirring portion coupled to the semiconductor body and provided with at least one first suspended beam configured for being moved in a second direction so as to generate, in use, agitation of the fluid present in said well.

    Abstract translation: 一种微流体装置，包括：半导体本体，具有在第一方向上彼此相对的第一侧和第二侧; 以及至少一个孔，构造成用于容纳流体，所述流体在所述半导体本体中从所述第一侧开始并且在底部由底面限定。 微流体装置还包括集成在底表面中的井中的搅拌结构，搅拌结构包括耦合到半导体主体并设置有至少一个第一悬置梁的第一搅拌部分，所述第一悬吊梁被配置为沿第二方向移动，以便 在使用中产生在所述井中存在的流体的搅动。

    Microfluidic device with integrated stirring structure and manufacturing method thereof
    7.
    发明授权
    Microfluidic device with integrated stirring structure and manufacturing method thereof 有权
    具有集成搅拌结构的微流体装置及其制造方法

    公开(公告)号：US09394160B2

    公开(公告)日：2016-07-19

    申请号：US14250098

    申请日：2014-04-10

    Applicant: STMicroelectronics S.r.l.

    Inventor： Sabrina Conoci ,  Paolo Ferrari

    IPC: B81C1/00 ,  B01F11/00 ,  B01F13/00 ,  B01L3/00 ,  C12M1/06

    CPC classification number: B81C1/00198 ,  B01F11/0082 ,  B01F13/0059 ,  B01F13/0091 ,  B01L3/502707 ,  B01L3/50273 ,  B01L2200/12 ,  B01L2300/06 ,  B81C1/00166 ,  B81C1/00182 ,  C12M27/02 ,  Y10T29/49009

    Abstract: A microfluidic device, comprising: a semiconductor body, having a first side and a second side, opposite to one another in a first direction; and at least one well, configured for containing a fluid, extending in the semiconductor body starting from the first side and being delimited at the bottom by a bottom surface. The microfluidic device further comprises a stirring structure integrated in the well at the bottom surface, the stirring structure including a first stirring portion coupled to the semiconductor body and provided with at least one first suspended beam configured for being moved in a second direction so as to generate, in use, agitation of the fluid present in said well.

    Abstract translation: 一种微流体装置，包括：半导体本体，具有在第一方向上彼此相对的第一侧和第二侧; 以及至少一个孔，构造成用于容纳流体，所述流体在所述半导体本体中从所述第一侧开始并且在底部由底面限定。 微流体装置还包括集成在底表面中的井中的搅拌结构，搅拌结构包括耦合到半导体主体并设置有至少一个第一悬置梁的第一搅拌部分，所述第一悬吊梁被配置为沿第二方向移动，以便 在使用中产生在所述井中存在的流体的搅动。

    MICROFLUIDIC DEVICE WITH INTEGRATED STIRRING STRUCTURE AND MANUFACTURING METHOD THEREOF
    8.
    发明申请
    MICROFLUIDIC DEVICE WITH INTEGRATED STIRRING STRUCTURE AND MANUFACTURING METHOD THEREOF 审中-公开
    具有集成式搅拌结构的微流体装置及其制造方法

    公开(公告)号：US20160090302A1

    公开(公告)日：2016-03-31

    申请号：US14963052

    申请日：2015-12-08

    Applicant: STMicroelectronics S.r.l.

    Inventor： Sabrina Conoci ,  Paolo Ferrari

    IPC: B81C1/00 ,  B01L3/00

    CPC classification number: B81C1/00198 ,  B01F11/0082 ,  B01F13/0059 ,  B01F13/0091 ,  B01L3/502707 ,  B01L3/50273 ,  B01L2200/12 ,  B01L2300/06 ,  B81C1/00166 ,  B81C1/00182 ,  C12M27/02 ,  Y10T29/49009

    Abstract: A microfluidic device, comprising: a semiconductor body, having a first side and a second side, opposite to one another in a first direction; and at least one well, configured for containing a fluid, extending in the semiconductor body starting from the first side and being delimited at the bottom by a bottom surface. The microfluidic device further comprises a stirring structure integrated in the well at the bottom surface, the stirring structure including a first stirring portion coupled to the semiconductor body and provided with at least one first suspended beam configured for being moved in a second direction so as to generate, in use, agitation of the fluid present in said well.

    Abstract translation: 一种微流体装置，包括：半导体本体，具有在第一方向上彼此相对的第一侧和第二侧; 以及至少一个孔，构造成用于容纳流体，所述流体在所述半导体本体中从所述第一侧开始并且在底部由底面限定。 微流体装置还包括集成在底表面中的井中的搅拌结构，搅拌结构包括耦合到半导体主体并设置有至少一个第一悬置梁的第一搅拌部分，所述第一悬吊梁被配置为沿第二方向移动，以便 在使用中产生在所述井中存在的流体的搅动。

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