公开(公告)号：US20240226824A9

公开(公告)日：2024-07-11

申请号：US18546612

申请日：2022-02-23

申请人： AFFIVAL

发明人： Matthias DARRINGTON

IPC分类号： B01F25/422 ,  B01F25/421 ,  B01F25/431 ,  B01F25/432 ,  B01F25/452 ,  B01F35/00

CPC分类号： B01F25/422 ,  B01F25/4233 ,  B01F25/43197 ,  B01F25/432 ,  B01F25/45241 ,  B01F35/561

摘要： The present disclosure relates to a mixer device having a housing including at least first and second adjacent mixing cells (2, 3), each cell (2, 3) including a fluid inlet opening (21, 31) and a fluid outlet opening (22, 32), the inlet opening being offset from the outlet opening so that the axis of the inlet opening is parallel to the axis of the outlet opening, the outlet opening of the first cell being connected to the inlet opening of the second cell via a connecting channel.

公开(公告)号：US11666874B2

公开(公告)日：2023-06-06

申请号：US16052705

申请日：2018-08-02

申请人： Massachusetts Institute of Technology

发明人： David Lai ,  Filippos Touriomousis ,  Andreas Mershin ,  Neil Gershenfeld

IPC分类号： B01F23/41 ,  B01F33/3011 ,  C09D11/102 ,  A61K9/107 ,  B33Y80/00 ,  B01L3/00 ,  B01F33/81 ,  B01F35/00 ,  B01F35/22 ,  B01F101/22

CPC分类号： B01F33/3011 ,  A61K9/107 ,  B01F23/41 ,  B01F33/813 ,  B01F35/2202 ,  B01F35/561 ,  B01L3/502784 ,  B33Y80/00 ,  C09D11/102 ,  B01F23/4143 ,  B01F2101/22 ,  B01L2300/0887

摘要： The invention comprises a novel modular, generalizable meso-micro-nano-fluidic platform apparatus, design and methodology which in exemplary embodiments may be applied in conjunction with a novel external triggering and automation/feedback loop control mechanism deployed via computer to explore the phase space of single or double emulsification for applications including the encapsulation of hydrophilic active pharmacological ingredients (APIs). End use applications include the mass production of particulate encapsulation of hydrophobic or hydrophilic APIs with automatic or user-supervised feedback methodology to control and discover mass production or per-drug customized settings of interest for the manufacture of novel or extant therapeutics. This invention allows for a process to produce monodispersed particles of varying sizes and may be used to rapidly screen for optimal size for maximal bioavailability of API particles either on lab bench for in vitro dissolution or in vivo studies, and patient-specific handhelds for maximal drug inhalation.

公开(公告)号：US12011025B2

公开(公告)日：2024-06-18

申请号：US17961865

申请日：2022-10-07

申请人： SOCIETE DES PRODUITS NESTLE S.A.

发明人： Luis Clavier ,  Rafael Marcilla ,  Jean-Francois Chevalier

IPC分类号： A23P30/40 ,  A23G3/02 ,  A23G3/34 ,  B01F23/20 ,  B01F23/235 ,  B01F27/271 ,  B01F33/81 ,  B01F35/00 ,  B01F35/71 ,  B01F101/06 ,  B01F101/12

CPC分类号： A23P30/40 ,  A23G3/0012 ,  A23G3/0221 ,  B01F23/2351 ,  B01F23/291 ,  B01F27/2711 ,  B01F33/811 ,  B01F35/561 ,  B01F35/715 ,  B01F2101/06 ,  B01F2101/12

摘要： A method for aerating a pasty product and for mixing with another product is disclosed herein. In one example, the method includes passing a stream of pasty product to be aerated through an apparatus. The apparatus includes a housing, the housing including an inlet for the pasty product to be aerated an outlet for the aerated product. The apparatus further includes a gas injector for injecting a gas into the pasty product to be aerated. The apparatus further includes an intermediate mixing chamber and a secondary product introduction member. The method further includes injecting via the upstream gas injector a gas into the pasty product stream at a position upstream relative to the first set of a rotor and a stator. The method further includes injecting a secondary product via the secondary product introduction member into the intermediate mixing chamber.

公开(公告)号：US20230142172A1

公开(公告)日：2023-05-11

申请号：US17911096

申请日：2021-03-12

申请人： Japan Science and Technology Agency

发明人： Takasi NISISAKO

IPC分类号： B01F33/3012 ,  B01F33/30 ,  B01F33/3011 ,  B01F35/00 ,  B01F25/314 ,  B01F23/41 ,  B01F23/232 ,  B81B1/00

CPC分类号： B01F33/3012 ,  B01F33/30351 ,  B01F33/3011 ,  B01F35/561 ,  B01F25/31432 ,  B01F23/4143 ,  B01F23/2323 ,  B81B1/006 ,  B01F2215/0431 ,  B81B2201/057 ,  B81B2203/0338

摘要： A microdroplet/bubble-generating device comprising a slit and a row of a plurality of microflow paths is constructed, in such a manner that either a continuous phase or dispersion phase is supplied to the slit, and so that the end of the slit, the other supply port for the continuous phase or dispersion phase and the liquid recovery port are connected. The plurality of microflow paths each have a narrow part where the cross-sectional area of the flow channel is locally narrowed adjacent to or near the connection point between the slit and the microflow path. The continuous phase and dispersion phase that have met at the connection points flow into the narrow parts, and the dispersion phase is sheared at the narrow parts with the continuous phase flow as the driving force, forming droplets or gas bubbles of the dispersion phase. The product is recovered from the liquid recovery port.

公开(公告)号：US20240131481A1

公开(公告)日：2024-04-25

申请号：US18546612

申请日：2022-02-23

申请人： AFFIVAL

发明人： Matthias DARRINGTON

IPC分类号： B01F25/422 ,  B01F25/421 ,  B01F25/431 ,  B01F25/432 ,  B01F25/452 ,  B01F35/00

CPC分类号： B01F25/422 ,  B01F25/4233 ,  B01F25/43197 ,  B01F25/432 ,  B01F25/45241 ,  B01F35/561

摘要： The present disclosure relates to a mixer device having a housing including at least first and second adjacent mixing cells (2, 3), each cell (2, 3) including a fluid inlet opening (21, 31) and a fluid outlet opening (22, 32), the inlet opening being offset from the outlet opening so that the axis of the inlet opening is parallel to the axis of the outlet opening, the outlet opening of the first cell being connected to the inlet opening of the second cell via a connecting channel.

公开(公告)号：US20240115070A1

公开(公告)日：2024-04-11

申请号：US18545868

申请日：2023-12-19

申请人： VERSUNI HOLDING B.V.

发明人： Britt ROUMEN ,  Bart-Jan ZWART

IPC分类号： A47J31/44 ,  B01F25/312 ,  B01F35/00

CPC分类号： A47J31/4403 ,  B01F25/312 ,  B01F35/561

摘要： The invention provides a mixing apparatus. The mixing apparatus includes a first container, wherein the first container comprises: a first port; and a mixing chamber. The mixing apparatus further includes a second container, wherein the second container is adapted to receive the first container, and a seal disposed between the first container and the second container. In addition, the mixing apparatus includes a channel between the first port and the mixing chamber, wherein the channel is defined by the seal and the first container. In some examples, the seal includes: a first seal portion; and a transition seal portion, the transition portion comprising: a seal split; and an air intake channel.

公开(公告)号：US11882958B2

公开(公告)日：2024-01-30

申请号：US16958728

申请日：2018-12-20

申请人： KONINKLIJKE PHILIPS N.V.

发明人： Britt Roumen ,  Bart-Jan Zwart

IPC分类号： A47J31/44 ,  B01F25/312 ,  B01F35/00

CPC分类号： A47J31/4403 ,  B01F25/312 ,  B01F35/561

摘要： The invention provides a mixing apparatus. The mixing apparatus includes a first container, wherein the first container comprises: a first port; and a mixing chamber. The mixing apparatus further includes a second container, wherein the second container is adapted to receive the first container, and a seal disposed between the first container and the second container. In addition, the mixing apparatus includes a channel between the first port and the mixing chamber, wherein the channel is defined by the seal and the first container. In some examples, the seal includes: a first seal portion; and a transition seal portion, the transition portion comprising: a seal split; and an air intake channel.