公开(公告)号：US20180155299A1

公开(公告)日：2018-06-07

申请号：US15833494

申请日：2017-12-06

申请人： Nagaraju Birudukota ,  David Becker

发明人： Nagaraju Birudukota ,  David Becker

IPC分类号： C07D255/02 ,  C07D403/14 ,  C07D487/04 ,  C07C251/20 ,  C07C321/06 ,  C07C49/675 ,  C07B43/04 ,  C07B45/02

CPC分类号： C07D255/02 ,  A61P5/26 ,  C07B43/04 ,  C07B45/02 ,  C07C49/675 ,  C07C243/18 ,  C07C251/20 ,  C07C321/06 ,  C07C2603/06 ,  C07D249/08 ,  C07D257/10 ,  C07D261/08 ,  C07D271/08 ,  C07D403/14 ,  C07D487/02 ,  C07D487/04

摘要： An azasteroid mimic or an intermediate for the preparation of an azasteroid and azasteroid mimic is formed via an oxocycloalkenyl isoxazolium anhydrobase and its dimer. The dimer can be used to form mono- and dihydrazones, which can be an azasteroid mimic or an intermediate for the preparation of an azasteroid and azasteroid mimic. A method of preparation of the dimer and the azasteroid mimic or an intermediate for the preparation of an azasteroid and azasteroid mimic occurs with hydrazonation and, optionally, a subsequent dehydrazonation. The dimer can be converted by inserting a nitrogen atom into the six membered ring of to a C-17 position cyclohexenone moiety of the dimer to yield a reduced tetrazolo[1,5-a]azepin-8-yl group. A subsequent hydrozone formation at a benzylic ketone can be carried out to generate an azasteroid mimic with a (triazol-4-yl)imino substituent. Monohydrazones can be converted to their thione equivalents.

公开(公告)号：US20120035291A1

公开(公告)日：2012-02-09

申请号：US12849072

申请日：2010-08-03

申请人： Michael S. Matson ,  Mitchell D. Refvik ,  Eric J. Netemeyer ,  Colin Cameron ,  Alastair Robert Marrion ,  Anthony Colin Wright

发明人： Michael S. Matson ,  Mitchell D. Refvik ,  Eric J. Netemeyer ,  Colin Cameron ,  Alastair Robert Marrion ,  Anthony Colin Wright

IPC分类号： C08F2/46 ,  C08G75/14 ,  C08K5/524

CPC分类号： C09J175/04 ,  C07C319/04 ,  C07C321/06 ,  C07C321/10 ,  C07C321/22 ,  C07C2601/14 ,  C07C2601/18 ,  C07C2601/20 ,  C09J11/06 ,  C09J163/00 ,  C09J201/00

摘要： The present invention discloses processes for forming polythiol compositions from olefinic hydrocarbons such as cyclooctadiene, cyclododecatriene, and trivinylcyclohexane. The polythiol compositions produced from these processes, including the sulfur-containing compounds of these compositions, also are described.

摘要翻译： 本发明公开了由烯烃如环辛二烯，环十二碳三烯和三乙烯基环己烷形成多硫醇组合物的方法。 还描述了由这些方法制备的多硫醇组合物，包括这些组合物的含硫化合物。

公开(公告)号：US3567608A

公开(公告)日：1971-03-02

申请号：US3567608D

申请日：1968-04-29

申请人： PHILLIPS PETROLEUM CO

发明人： WARNER PAUL F

IPC分类号： B01J1/10 ,  C07C3/24

CPC分类号： C07C319/04 ,  C07C2601/14 ,  C07C2601/16 ,  C07C2602/42 ,  Y10S204/908 ,  C07C321/06 ,  C07C321/22

摘要： THE REACTION RATE AND CONVERSION OF ETHYLEMICALLY UNSATURATED COMPOUNDS AND HYDROGEN SULFIDE CARRIED OUT IN THE PRESENCE OF ULTRAVIOLET RADIATION IS IMPROVED BY THE UTILIZATION IN THE REACTION SYSTEM OF A COMBINATION PROMOTER CONSISTING OF A PHOSPHITE OF THE FORMULA (ARO)2P AND AZOBISISOBUTYRONITRILE.

公开(公告)号：US3369040A

公开(公告)日：1968-02-13

申请号：US23185262

申请日：1962-10-19

申请人： SHELL OIL CO

发明人： DE ACETIS WILLIAM

IPC分类号： C07D339/06 ,  C08G59/30 ,  C08G59/66

CPC分类号： C08G59/66 ,  C07C321/04 ,  C07C321/06 ,  C07C321/22 ,  C07C323/12 ,  C07C323/16 ,  C07C2601/14 ,  C07D339/06 ,  C08G59/302

公开(公告)号：US11905236B2

公开(公告)日：2024-02-20

申请号：US17042667

申请日：2019-04-04

申请人： CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)

发明人： Igancio Alfonso Rodriguez ,  Jordi Sola Oller ,  Maria Lafuente Fabra

IPC分类号： G01N33/58 ,  G01N33/68 ,  C07C321/06

CPC分类号： C07C321/06 ,  G01N33/582 ,  G01N33/6815

摘要： The present invention relates to a dynamic chemical network that mimics the transfer of information and ultimately produces a chemical response, for example a readable signal. More specifically, the invention discloses a dynamic system able to selectively sense a biologically-relevant analyte, such as cysteine, in its reduced or its oxidized form (cystine) in aqueous media and in a biofluid (such as urine) for diagnostic application. Due to this property, said dynamic system is useful for the detection of cysteine or its derivatives in biological fluids such as urine.

公开(公告)号：US09945852B2

公开(公告)日：2018-04-17

申请号：US14115929

申请日：2012-05-04

申请人： Christopher David Gwenin ,  Mark Stephen Baird ,  Vanessa Valerie Gwenin ,  Mark Pitts

发明人： Christopher David Gwenin ,  Mark Stephen Baird ,  Vanessa Valerie Gwenin ,  Mark Pitts

IPC分类号： G01N33/569 ,  C07H13/04 ,  C07C321/06 ,  G01N33/58

CPC分类号： G01N33/5695 ,  C07C321/06 ,  C07H13/04 ,  G01N33/585

摘要： A method of determining the presence or absence in a sample of a biomarker, the method comprising: (a) linking an antigen to colloidal gold to provide a gold-antigen species; (b) contacting the gold-antigen species with the sample; (c) adding a diagnosis agent to the sample; and (d) observing the color of the sample.

公开(公告)号：US09340715B2

公开(公告)日：2016-05-17

申请号：US14820610

申请日：2015-08-07

申请人： Chevron Phillips Chemical Company LP

发明人： Michael S. Matson ,  Colin Cameron ,  Alastair Robert Marrion ,  Anthony Colin Wright ,  Mitchell D. Refvik ,  Eric J. Netemeyer

IPC分类号： C08J11/06 ,  C09J175/04 ,  C09J201/00 ,  C09J163/00 ,  C07C319/04 ,  C07C321/06 ,  C07C321/10 ,  C07C321/22 ,  C09J11/06 ,  C08G75/10 ,  C08G75/14 ,  C08G75/16

CPC分类号： C09J175/04 ,  C07C319/04 ,  C07C321/06 ,  C07C321/10 ,  C07C321/22 ,  C07C2601/14 ,  C07C2601/18 ,  C07C2601/20 ,  C09J11/06 ,  C09J163/00 ,  C09J201/00

摘要： The present invention discloses processes for forming polythiol compositions from olefinic hydrocarbons such as cyclooctadiene, cyclododecatriene, and trivinylcyclohexane. The polythiol compositions produced from these processes, including the sulfur-containing compounds of these compositions, also are described.

公开(公告)号：US20150344756A1

公开(公告)日：2015-12-03

申请号：US14822957

申请日：2015-08-11

申请人： Chevron Phillips Chemical Company LP

发明人： Michael S. Matson ,  Colin Cameron ,  Alastair Robert Marrion ,  Anthony Colin Wright ,  Mitchell D. Refvik ,  Eric J. Netemeyer

IPC分类号： C09J201/00

CPC分类号： C09J175/04 ,  C07C319/04 ,  C07C321/06 ,  C07C321/10 ,  C07C321/22 ,  C07C2601/14 ,  C07C2601/18 ,  C07C2601/20 ,  C09J11/06 ,  C09J163/00 ,  C09J201/00

摘要： The present invention discloses processes for forming polythiol compositions from olefinic hydrocarbons such as cyclooctadiene, cyclododecatriene, and trivinylcyclohexane. The polythiol compositions produced from these processes, including the sulfur-containing compounds of these compositions, also are described.

公开(公告)号：US07173156B1

公开(公告)日：2007-02-06

申请号：US11279153

申请日：2006-04-10

申请人： Brian T Holmes ,  Arthur W Snow

发明人： Brian T Holmes ,  Arthur W Snow

IPC分类号： C07C319/02

CPC分类号： C07C319/02 ,  C07C2601/14 ,  C07C321/04 ,  C07C321/06 ,  C07C321/10 ,  C07C323/03 ,  C07C323/07 ,  C07C323/12 ,  C07C323/16

摘要： A method of thioacetate deprotection by providing a compound of the formula R1—S—CO—R2, and reacting the compound with a quaternary ammonium cyanide salt in the presence of a protic solvent in an inert atmosphere to convert the compound to a product of the formula R1—SH. R1 is an organic group in which the bonding to sulfur is through a saturated carbon, and R2 is an aliphatic group.

摘要翻译： 通过提供式R 1 -S-CO-R 2的化合物的硫代乙酸酯去保护的方法，并使化合物与氰化季铵盐在 在惰性气氛中的质子溶剂将化合物转化成式R 1 -SH的产物。 R 1是其中与硫结合通过饱和碳的有机基团，R 2是脂族基团。

公开(公告)号：US20180072839A1

公开(公告)日：2018-03-15

申请号：US15681411

申请日：2017-08-20

申请人： Chi Mei Corporation

发明人： Hsiu-Mei Wu ,  Yi-Hsiu Huang ,  Chan-Li Hsueh

IPC分类号： C08G18/72 ,  C08G18/83

CPC分类号： C08G18/72 ,  C07C321/06 ,  C08G18/3876 ,  C08G18/722 ,  C08G18/755 ,  C08G18/758 ,  C08G18/834 ,  G02B1/041 ,  C08L75/04 ,  C08L81/00

摘要： A resin composition for an optical material contains a thiol compound and an isocyanate compound. The thiol compound includes a trithiol compound and a tetrathiol compound, and based on 100% of the total mole equivalent of the thiol group of the thiol compound, the total mole equivalent of the thiol group of the trithiol compound is fro 85% to 95%, and the total mole equivalent of the thiol group of the tetrathiol compound is from 5% to 15%. The isocyanate compound includes dicyclohexylmethane diisocyanate, and based on 100% of the total mole equivalent of the isocyanate group of the isocyanate compound, the total mole equivalent of the isocyanate group of the dicyclohexylmethane diisocyanate is from 90% to 100%.