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公开(公告)号：US08361756B2
公开(公告)日：2013-01-29
申请号：US12441272
申请日：2007-09-14
CPC分类号： C12N9/24 , A23C9/206 , A23L33/40 , A23V2002/00 , C12N9/18 , C12N9/2402 , C12N9/2471 , C12N9/88 , C12N9/90 , C12P19/00 , C12P19/04 , C12Y301/01053 , C12Y302/01018 , C12Y302/01023 , C12Y302/01051 , C12Y302/01052 , C12Y403/03007 , C12Y501/03009 , A23V2250/28 , A23V2200/3202
摘要： This invention provides nucleic acids and proteins involved in oligosaccharide modification in the species Bifidobacteria. The invention provides methods for utilizing the proteins of the invention to generate human milk oligosaccharides or oligosaccharide mimics. The invention also provides compositions containing the human milk oligosaccharides or oligosaccharide mimics and methods for use.
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公开(公告)号：US20100113383A1
公开(公告)日：2010-05-06
申请号：US12441272
申请日：2007-09-14
CPC分类号： C12N9/24 , A23C9/206 , A23L33/40 , A23V2002/00 , C12N9/18 , C12N9/2402 , C12N9/2471 , C12N9/88 , C12N9/90 , C12P19/00 , C12P19/04 , C12Y301/01053 , C12Y302/01018 , C12Y302/01023 , C12Y302/01051 , C12Y302/01052 , C12Y403/03007 , C12Y501/03009 , A23V2250/28 , A23V2200/3202
摘要： This invention provides nucleic acids and proteins involved in oligosaccharide modification in the species Bifidobacteria. The invention provides methods for utilizing the proteins of the invention to generate human milk oligosaccharides or oligosaccharide mimics. The invention also provides compositions containing the human milk oligosaccharides or oligosaccharide mimics and methods for use.
摘要翻译： 本发明提供了在双歧杆菌物种中参与寡糖修饰的核酸和蛋白质。 本发明提供了利用本发明的蛋白质产生人乳低聚糖或寡糖模拟物的方法。 本发明还提供含有人乳低聚糖或寡糖模拟物的组合物和使用方法。
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公开(公告)号：US08999705B2
公开(公告)日：2015-04-07
申请号：US13720866
申请日：2012-12-19
IPC分类号： C12N9/24 , C12P19/00 , C07H21/04 , A23C9/20 , A23L1/29 , C12N9/18 , C12N9/88 , C12N9/90 , C12P19/04 , C12N9/38
CPC分类号： C12N9/24 , A23C9/206 , A23L33/40 , A23V2002/00 , C12N9/18 , C12N9/2402 , C12N9/2471 , C12N9/88 , C12N9/90 , C12P19/00 , C12P19/04 , C12Y301/01053 , C12Y302/01018 , C12Y302/01023 , C12Y302/01051 , C12Y302/01052 , C12Y403/03007 , C12Y501/03009 , A23V2250/28 , A23V2200/3202
摘要： This invention provides nucleic acids and proteins involved in oligosaccharide modification in the species Bifidobacteria. The invention provides methods for utilizing the proteins of the invention to generate human milk oligosaccharides or oligosaccharide mimics. The invention also provides compositions containing the human milk oligosaccharides or oligosaccharide mimics and methods for use.
摘要翻译： 本发明提供了在双歧杆菌物种中参与寡糖修饰的核酸和蛋白质。 本发明提供了利用本发明的蛋白质产生人乳低聚糖或寡糖模拟物的方法。 本发明还提供含有人乳低聚糖或寡糖模拟物的组合物和使用方法。
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4.发明申请Novel Purified dihydrodipicolinate synthase polypeptides and structures thereof 审中-公开新型纯化二氢吡啶二羧酸合酶多肽及其结构公开(公告)号：US20070048814A1
公开(公告)日：2007-03-01
申请号：US11224753
申请日：2005-09-12
申请人： Aled Edwards , Akil Dharamsi , Matthew Kimber
发明人： Aled Edwards , Akil Dharamsi , Matthew Kimber
CPC分类号： C12N9/88 , C12Q1/527 , C12Y403/03007
摘要： The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
摘要翻译： 本发明涉及病原菌的新型药物靶标。 因此，本发明提供了包含SEQ ID NO：4所示氨基酸序列的纯化蛋白质。本发明还提供本发明多肽的生物化学和生物物理学特征。
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5.发明授权Mutant microorganism having high production of cadaverine, and preparation method of cadaverine using same 有权具有高死亡率的突变体微生物及其使用的尸胺的制备方法公开(公告)号：US09115362B2
公开(公告)日：2015-08-25
申请号：US13813949
申请日：2011-08-03
申请人： Sang Yup Lee , Zhi Gang Qian , Xiaoxia Xia , Min Young Kim
发明人： Sang Yup Lee , Zhi Gang Qian , Xiaoxia Xia , Min Young Kim
CPC分类号： C12N15/70 , C12N9/001 , C12N9/1029 , C12N9/104 , C12N9/1085 , C12N9/1096 , C12N9/88 , C12N9/93 , C12N15/52 , C12P13/001 , C12Y103/01026 , C12Y203/01057 , C12Y205/01016 , C12Y206/01082 , C12Y401/0102 , C12Y402/01051 , C12Y403/03007
摘要： The present invention relates to a mutant microorganism having a high ability to produce cadaverine, and a method for producing cadaverine using the same. More specifically, the invention relates to a mutant microorganism having a high ability to produce cadaverine wherein a gene involved in the cadaverine degradation or utilization pathway is inactivated or deleted, and to a method for producing cadaverine in high yield by culturing the mutant microorganism under aerobic conditions. The mutant microorganism according to the present invention is useful for producing a high yield of cadaverine which can be widely used in various industrial applications.
摘要翻译： 本发明涉及具有高的生产尸胺能力的突变微生物，以及使用该活性的生物化学品的方法。 更具体地，本发明涉及具有高生产能力的突变体微生物，其中参与尸胺降解或利用途径的基因被失活或缺失，以及通过在需氧下培养突变型微生物而以高产率生产尸胺的方法 条件。 根据本发明的突变体微生物可用于生产可广泛用于各种工业应用中的高产量的尸胺。
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6.发明申请MUTANT MICROORGANISM HAVING HIGH PRODUCTION OF CADAVERINE, AND PREPARATION METHOD OF CADAVERINE USING SAME 有权具有高生产率的复方微生物，以及使用其的CADAVERINE的制备方法公开(公告)号：US20130157323A1
公开(公告)日：2013-06-20
申请号：US13813949
申请日：2011-08-03
申请人： Sang Yup Lee , Zhi Gang Qian , Xiaoxia Xia , Min Young Kim
发明人： Sang Yup Lee , Zhi Gang Qian , Xiaoxia Xia , Min Young Kim
CPC分类号： C12N15/70 , C12N9/001 , C12N9/1029 , C12N9/104 , C12N9/1085 , C12N9/1096 , C12N9/88 , C12N9/93 , C12N15/52 , C12P13/001 , C12Y103/01026 , C12Y203/01057 , C12Y205/01016 , C12Y206/01082 , C12Y401/0102 , C12Y402/01051 , C12Y403/03007
摘要： The present invention relates to a mutant microorganism having a high ability to produce cadaverine, and a method for producing cadaverine using the same. More specifically, the invention relates to a mutant microorganism having a high ability to produce cadaverine wherein a gene involved in the cadaverine degradation or utilization pathway is inactivated or deleted, and to a method for producing cadaverine in high yield by culturing the mutant microorganism under aerobic conditions. The mutant microorganism according to the present invention is useful for producing a high yield of cadaverine which can be widely used in various industrial applications.
摘要翻译： 本发明涉及具有高的生产尸胺能力的突变微生物，以及使用该活性的生物化学品的方法。 更具体地，本发明涉及具有高生产能力的突变体微生物，其中参与尸胺降解或利用途径的基因被失活或缺失，以及通过在需氧下培养突变型微生物而以高产率生产尸胺的方法 条件。 根据本发明的突变体微生物可用于生产可广泛用于各种工业应用中的高产量的尸胺。
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公开(公告)号：US20130095528A1
公开(公告)日：2013-04-18
申请号：US13720866
申请日：2012-12-19
CPC分类号： C12N9/24 , A23C9/206 , A23L33/40 , A23V2002/00 , C12N9/18 , C12N9/2402 , C12N9/2471 , C12N9/88 , C12N9/90 , C12P19/00 , C12P19/04 , C12Y301/01053 , C12Y302/01018 , C12Y302/01023 , C12Y302/01051 , C12Y302/01052 , C12Y403/03007 , C12Y501/03009 , A23V2250/28 , A23V2200/3202
摘要： This invention provides nucleic acids and proteins involved in oligosaccharide modification in the species Bifidobacteria. The invention provides methods for utilizing the proteins of the invention to generate human milk oligosaccharides or oligosaccharide mimics. The invention also provides compositions containing the human milk oligosaccharides or oligosaccharide mimics and methods for use.
摘要翻译： 本发明提供了在双歧杆菌物种中参与寡糖修饰的核酸和蛋白质。 本发明提供了利用本发明的蛋白质产生人乳低聚糖或寡糖模拟物的方法。 本发明还提供含有人乳低聚糖或寡糖模拟物的组合物和使用方法。
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