公开(公告)号：US11918191B2

公开(公告)日：2024-03-05

申请号：US17746083

申请日：2022-05-17

申请人： Hannah Life Technologies PTE, Ltd.

发明人： Prusothman Sina Raja ,  Chee Keong Tee ,  Vivek Murali ,  Zongyuan Xu ,  Shruthi Pandi Chelvam

IPC分类号： A61B90/00 ,  A61B10/00 ,  A61B17/425

CPC分类号： A61B10/0058 ,  A61B90/03 ,  A61B17/425 ,  A61B2560/04

摘要： A conception aid for assisting in natural conception may include a platform configured for placement in a vaginal canal, wherein the platform comprises one or more capturing elements configured to collect semen. A method of aiding conception may include providing a conception aid device including one or more capturing elements, collecting semen with the one or more capturing elements wherein the one or more capturing elements is configured to contain the collected semen on the device, and positioning the device in a vaginal canal.

公开(公告)号：US20200297384A1

公开(公告)日：2020-09-24

申请号：US16898090

申请日：2020-06-10

申请人： CrossBay Medical, Inc.

发明人： Steven R. BACICH ,  Matthew Thomas YUREK ,  Cristiano Danilo Maria FONTANA ,  Piush VIDYARTHI

IPC分类号： A61B17/425 ,  A61B17/43 ,  A61B17/435 ,  A61M25/01

摘要： Everting balloon systems and methods for using the same with an alignment element for stability and anti-rotation of the everting balloon are disclosed herein. The systems can be configured to access and deliver instruments, media, or other catheters into bodily lumens and cavities. The alignment element can eliminate the potential for the everting membrane to become twisted or rotated which could impact access or the ability of the system to deliver materials. A compliance member can facilitate internal pressurization of the everting catheter system. An everting catheter system can be configured for use with transvaginal ultrasound and a lower profile speculum is described.

公开(公告)号：US10438686B2

公开(公告)日：2019-10-08

申请号：US15242215

申请日：2016-08-19

申请人： The Board of Trustees of the Leland Stanford Junior University

发明人： Mylene W. M. Yao ,  Wing H. Wong

IPC分类号： G16B5/00 ,  A61B17/425 ,  G16B25/00 ,  G16B40/00 ,  C12Q1/6809 ,  C12Q1/6883 ,  G06F19/00 ,  G16H10/60 ,  G16B20/00

摘要： Methods and computer-based systems for facilitating assessment of clinical infertility are provided. The methods and systems can be implemented to, for example, facilitate assessment of a subject for an in vitro fertilization treatment cycle, including determining probability of a live birth event. The methods and systems can be implemented to, for example, facilitate a determination of success implantation of embryos, selection of an optimal number of embryos to transfer, and determination of success in subsequent in vitro fertilization treatment cycles following an unsuccessful treatment cycle.

公开(公告)号：US10159510B2

公开(公告)日：2018-12-25

申请号：US15210252

申请日：2016-07-14

申请人： Truth in Design, Inc.

发明人： Sherman Souther ,  Hamilton Souther

IPC分类号： A61B17/425 ,  A61B17/43

摘要： A device and method for improving fertility among couples after intercourse is disclosed. The device and method uses an intravaginal device that collects ejaculate from the vaginal canal after intercourse and presents it to the os of the cervix. The device also serves to contain ejaculate near the cervical os to increase the chances of successful fertilization.

公开(公告)号：US20170166882A1

公开(公告)日：2017-06-15

申请号：US15115380

申请日：2015-01-28

申请人： LEIBNIZ-INSTITUT FUER FESTKOERPER-UND WERKSTOFFFORSCHUNG DRESDEN E.V.

发明人： Oliver G. SCHMIDT

IPC分类号： C12N11/14 ,  A61K41/00 ,  A61B17/425 ,  C12N5/076

CPC分类号： C12N11/14 ,  A61B17/425 ,  A61K41/00 ,  C12N5/061 ,  C12N5/0612

摘要： The invention concerns the fields of microtechnologies, biology and medicine and relates to a method for producing mobility in immobile cells as can be used, for example, for in vivo or in vitro fertilization.The object of the present invention is to specify a method for producing mobility in individual immobile cells, with which method activity and guided mobility in previously immobile cells can be achieved.The object is attained with a method for producing mobility in immobile cells in which an immobile cell is connected to a microstructure, .wherein the microstructure is composed at least partially of magnetic materials and a non-reciprocal movement of the microstructure with the immobile cell is executed by means of a time-varying, three-dimensional external magnetic field.

公开(公告)号：US09348972B2

公开(公告)日：2016-05-24

申请号：US13182360

申请日：2011-07-13

申请人： Mylene Yao

发明人： Mylene Yao

IPC分类号： A61B17/425 ,  A61B17/435 ,  A61D19/04 ,  G06F19/00

CPC分类号： G06F19/3431 ,  A61B17/425 ,  A61B17/435 ,  A61D19/04 ,  G06F19/00 ,  G16H50/30 ,  G16H50/50

摘要： Provided is a multiple birth prognostic tool that is used to analyze data in order to predict a multiple birth event in a female human patient undergoing an infertility treatment. The MBP prognostic tool may also be used to enhance the accuracy of diagnostic or prognostic tests that predict embryo viability. The MBP prognostic tool of the present invention may be clinic specific or it may be modified to be used in a multi-clinic approach.

摘要翻译： 提供了一种多发生预后工具，用于分析数据，以预测在不孕不育治疗的女性人类患者中的多发性事件。 MBP预后工具还可用于增强预测胚胎存活力的诊断或预后测试的准确性。 本发明的MBP预后工具可以是临床特异性的，或者可以修改以用于多临床方法。

公开(公告)号：US09157550B2

公开(公告)日：2015-10-13

申请号：US12652735

申请日：2010-01-05

申请人： Matthew B. Wheeler ,  Dongshin Kim ,  David J. Beebe

发明人： Matthew B. Wheeler ,  Dongshin Kim ,  David J. Beebe

IPC分类号： C12M1/34 ,  F16K99/00 ,  C12M3/06 ,  C12M3/00 ,  A61B17/425 ,  B01L3/00

CPC分类号： F16K99/0001 ,  A61B17/425 ,  B01L3/5085 ,  B01L2300/0829 ,  C12M21/06 ,  C12M23/16 ,  F16K99/0017 ,  F16K99/0028 ,  Y10T137/0318 ,  Y10T137/87249

摘要： Microfluidic systems and methods. A microfluidic device for in vitro fertilization comprises a substrate and a plurality of microchannels disposed in the substrate, including an inlet of at least two of the plurality of microchannels arranged on the substrate to align with a fluid-handling device. Another microfluidic system for assaying a plurality of cells comprises a substrate and a plurality of microfluidic channels comprising a source channel, a sink channel, and a cell chamber. An insert for a microfluidic system comprises a substrate configured to be inserted into a dish and a plurality of microscale wells disposed in the substrate. A microfluidic channel comprises a substrate and at least one microchannel having an open inlet, an open outlet, a channel, and an opening in the substrate disposed over a portion of the channel. A device for providing an amount of fluid for a fluidic system comprises a main reservoir, an aspiration well, tubing coupling the reservoirs, and a seal closing the main reservoir. Air tubing having a hydrophobic end extends into the at least one aspiration well.

摘要翻译： 微流体系统和方法。 用于体外受精的微流体装置包括衬底和设置在衬底中的多个微通道，包括布置在衬底上的多个微通道中的至少两个的入口，以与流体处理装置对准。 用于测定多个细胞的另一个微流体系统包括底物和多个包含源通道，宿通道和细胞室的微流体通道。 用于微流体系统的插入件包括构造成插入盘中的衬底和设置在衬底中的多个微孔。 微流体通道包括基底和至少一个具有开放入口，开口的出口，通道和布置在通道的一部分上的基底中的开口的微通道。 用于为流体系统提供一定量的流体的装置包括主储存器，抽吸井，联接储存器的管道和封闭主储存器的密封件。 具有疏水端的空气管延伸到至少一个抽吸井中。

公开(公告)号：US20120271100A1

公开(公告)日：2012-10-25

申请号：US13442453

申请日：2012-04-09

申请人： Teresa K. Woodruff ,  Thomas V. O'Halloran ,  Alison M. Kim ,  Emily Que ,  Betty Kong ,  Miranda Bernhardt

发明人： Teresa K. Woodruff ,  Thomas V. O'Halloran ,  Alison M. Kim ,  Emily Que ,  Betty Kong ,  Miranda Bernhardt

IPC分类号： C07F5/02 ,  A61B17/425 ,  G01N21/64

CPC分类号： G01N33/5091 ,  A61B17/435 ,  A61D19/04 ,  G01N21/6428 ,  G01N21/643

摘要： The invention relates generally to compositions and methods for the detection of zinc. In particular, compositions and methods are provided to detect changes in cellular zinc concentration and to correlate them to cellular phenomena.

摘要翻译： 本发明一般涉及用于检测锌的组合物和方法。 特别地，提供组合物和方法以检测细胞锌浓度的变化并将其与细胞现象相关联。

公开(公告)号：US20120046260A1

公开(公告)日：2012-02-23

申请号：US13286127

申请日：2011-10-31

申请人： Kathy Lee-Sepsick ,  Jeffrey A. Marcus ,  Max S. Azevedo ,  Daniel S. Currie

发明人： Kathy Lee-Sepsick ,  Jeffrey A. Marcus ,  Max S. Azevedo ,  Daniel S. Currie

IPC分类号： A61K31/57 ,  A61P15/00 ,  A61B17/435 ,  A61K31/519 ,  A61B17/425 ,  A61B17/43

CPC分类号： A61M31/00 ,  A61B17/12022 ,  A61B17/12099 ,  A61B17/12159 ,  A61B17/12186 ,  A61B17/1219 ,  A61B17/12195 ,  A61B17/22012 ,  A61B17/320758 ,  A61B17/42 ,  A61B17/43 ,  A61B17/435 ,  A61B2017/22051 ,  A61B2017/22084 ,  A61B2017/4225 ,  A61B2017/4233 ,  A61F6/005 ,  A61F6/225 ,  A61M31/005

摘要： The present invention comprises systems, methods and devices for the delivery of visualizable or treatment compositions or therapeutic agents comprising device elements for diagnosis and/or treatment of conduits. A delivery system comprising an introducer shaft having at least one exit port and at least one delivery catheter for placement of compositions into the conduit, such as a fallopian tube.

摘要翻译： 本发明包括用于递送可视化或治疗组合物或治疗剂的系统，方法和装置，其包括用于诊断和/或治疗导管的装置元件。 一种输送系统，包括具有至少一个出口的导引器轴和用于将组合物放置在诸如输卵管的导管中的至少一个输送导管。

公开(公告)号：US20120029270A1

公开(公告)日：2012-02-02

申请号：US12848154

申请日：2010-07-31

申请人： CHRISTINE STUART

发明人： CHRISTINE STUART

IPC分类号： A61B17/425

CPC分类号： A61B17/425 ,  A61F6/065 ,  A61F6/08

摘要： The present invention relates to a cervical condom for aiding in conception comprising: a dome shape flexible device, where said device is made of a flexible material; and a rim surrounding the outer perimeter of the device. The device is capable of containing a sperm sample for application upon a user's cervix. In one exemplary embodiment, the flexible material is silicone and the condom measures in a range of about two to five centimeters in length.

摘要翻译： 本发明涉及一种用于辅助受孕的子宫颈避孕套，包括：圆顶形柔性装置，其中所述装置由柔性材料制成; 以及围绕设备的外周边的边缘。 该装置能够容纳用于应用于用户子宫颈的精子样品。 在一个示例性实施例中，柔性材料是硅树脂，并且避孕套的长度在约2至5厘米的范围内。