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    Method and apparatus for supplying gas to an area
    3.
    发明申请
    Method and apparatus for supplying gas to an area 失效
    向区域供气的方法和装置

    公开(公告)号：US20040260253A1

    公开(公告)日：2004-12-23

    申请号：US10781965

    申请日：2004-02-18

    Inventor： Coni F. Rosati

    IPC: A61F013/00 ,  A61F015/00

    CPC classification number: A61M35/00 ,  A61F13/0206 ,  A61F13/0209 ,  A61F13/0213 ,  A61F13/0216 ,  A61F13/0226 ,  A61F13/025 ,  A61H33/14 ,  A61H35/00

    Abstract: An apparatus for supplying one or more gases, such as oxygen, to a target area, comprising a top layer and a bottom layer sealed around the perimeter of the layers to form a reservoir between the layers, wherein the top layer is not gas-permeable and the bottom layer is highly gas-permeable, said reservoir containing one or more gases. The present invention also describes methods of using such an apparatus to supply oxygen to a wound for improved wound healing.

    Abstract translation: 一种用于将一种或多种气体（例如氧气）供应到目标区域的装置，包括围绕所述层的周边密封的顶层和底层，以在所述层之间形成储存器，其中所述顶层不是透气的 并且底层是高度透气的，所述储存器包含一种或多种气体。 本发明还描述了使用这种装置向伤口供氧以改善伤口愈合的方法。

    Wound dressing
    4.
    发明申请
    Wound dressing 有权
    伤口敷料

    公开(公告)号：US20040249328A1

    公开(公告)日：2004-12-09

    申请号：US10820270

    申请日：2004-04-08

    Inventor： Patrick G. Linnane ,  Helen L. Shaw

    IPC: A61F013/00

    CPC classification number: A61F13/0203 ,  A61F13/0226 ,  A61F2013/00412

    Abstract: A wound dressing for post-operative sites requiring drainage includes a thin film or film/foam laminate layer with an adhesive applied to one surface thereof and an absorbent layer positioned on the adhesive surface. The dressing has an aperture to accommodate a drainage tube and a slit extending from the aperture to an outer edge of the dressing.

    Abstract translation: 用于需要引流的手术后部位的伤口敷料包括薄膜或膜/泡沫层压层，其粘合剂施加到其一个表面上，吸收层位于粘合剂表面上。 该敷料具有一个孔，以容纳排水管和从该孔延伸至敷料的外边缘的狭缝。

    Wound dressing and method for controlling severe, life-threatening bleeding
    5.
    发明申请
    Wound dressing and method for controlling severe, life-threatening bleeding 有权
    伤口敷料和控制严重威胁生命的出血的方法

    公开(公告)号：US20040243043A1

    公开(公告)日：2004-12-02

    申请号：US10743052

    申请日：2003-12-23

    Inventor： Simon J, McCarthy ,  Kenton W. Gregory ,  William P. Wiesmann ,  Todd D. Campbell

    IPC: A61F013/00

    CPC classification number: A61F13/0203 ,  A61F5/40 ,  A61F13/00063 ,  A61F13/0253 ,  A61F13/0256 ,  A61F13/0276 ,  A61F13/0289 ,  A61F13/36 ,  A61F17/00 ,  A61F2013/00106 ,  A61F2013/00221 ,  A61F2013/00463 ,  A61F2013/00468 ,  A61F2013/00472 ,  A61F2013/0054 ,  A61F2013/00659 ,  A61F2013/00676 ,  A61F2013/0071 ,  A61F2013/00719 ,  A61F2013/00931 ,  A61L15/28 ,  A61L15/425 ,  A61L2400/04 ,  C08L1/00 ,  C08L5/08

    Abstract: This invention is directed to advanced hemorrhage control wound dressings, and methods of using and producing same. The subject wound dressing is constructed from a non-mammalian material for control of severe bleeding. The wound dressing for controlling severe bleeding is formed of a biomaterial comprising chitosan, a hydrophilic polymer, a polyacrylic polymer or a combination thereof. The kind of severe, life-threatening bleeding contemplated by this invention is typically of the type not capable of being stanched when a conventional gauze wound dressing is applied with conventional pressure to the subject wound. The wound dressing being capable of substantially stanching the flow of the severe life-threatening bleeding from the wound by adhering to the wound site, to seal the wound, to accelerate blood clot formation at the wound site, to reinforce clot formation at the wound site and prevent bleed out from the wound site, and to substantially prohibit the flow of blood out of the wound site.

    Abstract translation: 本发明涉及先进的出血控制伤口敷料，以及其使用和生产方法。 受试者伤口敷料由用于控制严重出血的非哺乳动物材料构成。 用于控制严重出血的伤口敷料由包含壳聚糖，亲水性聚合物，聚丙烯酸聚合物或其组合的生物材料形成。 本发明考虑的严重的威胁生命的出血通常是当将传统的纱布伤口敷料以常规压力施加到受试者伤口时不能被切断的类型。 伤口敷料能够通过粘附到伤口部位上来严重地伤害来自创伤的危及生命的出血的流动，以密封伤口，以加速伤口部位的血块形成，从而加强伤口部位的凝块形成 并且防止从伤口部位渗出，并且基本上禁止血液流出伤口部位。

    Ingestible device for the release of substances at distinct locations in alimentary canal
    6.
    发明申请
    Ingestible device for the release of substances at distinct locations in alimentary canal 失效
    用于在消化道不同位置释放物质的可摄入装置

    公开(公告)号：US20040215171A1

    公开(公告)日：2004-10-28

    申请号：US10176160

    申请日：2002-06-20

    Applicant: Phaeton Research Ltd.

    Inventor： Peter John Houzego ,  Peter Neil Morgan ,  Peter Hanson Hirst ,  Duncan James Westland ,  Ian Robert Wilding

    IPC: A61K009/22 ,  A61F013/00

    CPC classification number: A61M31/002

    Abstract: The field of the invention is site-specific drug delivery capsules (SSDC's). The disclosure relates to a closure member (14) for a substance reservoir (12) of an SSDC (10). The SSDC (10) includes a retainer that provides a non-linear force resisting opening of the closure member (14). The non-linear force ensures that the closure member (14) unseals the reservoir (12) only when an opening force exceeds a maximal value of the resisting force, thereby preventing premature or accidental emptying of the reservoir (12). The preferred means of providing the resistive force is a rolling, elastomeric o-ring (64) that additionally seals the closure member (14) into an aperture (13).

    Abstract translation: 本发明的领域是位点特异性药物递送胶囊（SSDC）。 本公开涉及一种用于SSDC（10）的物质储存器（12）的封闭构件（14）。 SSDC（10）包括提供关闭构件（14）的非线性抗力开口的保持器。 只有当打开力超过抵抗力的最大值时，非线性力才能确保关闭构件（14）开启储存器（12），从而防止储存器（12）的过早或意外排空。 提供阻力的优选方式是另外将封闭构件（14）密封成孔（13）的滚动弹性体O形环（64）。

    Demand-release bioactive composition for implantable medical devices
    8.
    发明申请
    Demand-release bioactive composition for implantable medical devices 有权
    可植入医疗器械的需求释放生物活性成分

    公开(公告)号：US20040180073A1

    公开(公告)日：2004-09-16

    申请号：US10386967

    申请日：2003-03-11

    Applicant: Medtronic, Inc.

    Inventor： Kenneth B. Stokes ,  Michael J. Ebert ,  Christopher M. Hobot

    IPC: A61F013/00

    CPC classification number: A61L31/16 ,  A61L27/54 ,  A61L2300/222 ,  A61L2300/41 ,  A61L2300/602 ,  A61L2300/606 ,  A61N1/056 ,  A61N1/0575

    Abstract: A biostable polymeric substrate of an implantable medical device unit includes a demand-release bioactive composition including one or more bioactive agents covalently bound to surface-modifying end groups of the substrate. Certain cellular activities, in proximity to the polymeric substrate, release substances reacting with the end groups such that the end groups release the one or more bioactive agents, which modify the certain cellular activities.

    Abstract translation: 植入式医疗装置单元的生物稳定的聚合物基质包括需求释放生物活性组合物，其包含与基底的表面改性端基共价结合的一种或多种生物活性剂。 在聚合物底物附近的某些细胞活性释放与端基反应的物质，使得端基释放一种或多种改变某些细胞活性的生物活性剂。

    Organ manipulator having suction member supported with freedom to move relative to its support
    9.
    发明申请
    Organ manipulator having suction member supported with freedom to move relative to its support 有权
    器官操纵器具有支撑自由以相对于其支撑件移动的抽吸构件

    公开(公告)号：US20040176659A1

    公开(公告)日：2004-09-09

    申请号：US10801024

    申请日：2004-03-15

    Inventor： Steven Peng ,  Larry Voss ,  David E. Hancock ,  Grace A. Carlson ,  John W. Davis ,  Albert K. Chin ,  Jaime S. Vargas

    IPC: A61B001/32 ,  A61F013/00

    CPC classification number: A61B17/02 ,  A61B17/085 ,  A61B2017/0243 ,  A61B2017/2905 ,  A61B2017/2929 ,  A61B2017/293 ,  A61B2017/308

    Abstract: An organ manipulator including at least one suction member or adhesive disc mounted to a compliant joint, a flexible locking arm for mounting such suction member or compliant joint, and a method for retracting and suspending an organ in a retracted position using suction (or adhesive force) so that the organ is free to move normally (e.g., to beat or undergo other limited-amplitude motion) in at least the vertical direction during both steps. In preferred embodiments, a suction member exerts suction to retract a beating heart and suspend it in a retracted position during surgery. As the retracted heart beats, the compliant joint allows it to expand and contract freely (and otherwise move naturally) at least in the vertical direction so that hemodynamic function is not compromised. The suction member conforms or can be conformed to the organ anatomy, and its inner surface is preferably smooth and lined with absorbent material to improve traction without causing trauma to the organ. The compliant joint can connect the member to an arm which is adjustably mounted to a sternal retractor or operating table. The compliant joint can be a sliding ball joint, a hinged joint, a pin sliding in a slot, a universal joint, a spring assembly, or another compliant element. In preferred embodiments, the method includes the steps of affixing a suction member to a beating heart at a position concentric with the heart's apex, and applying suction to the heart while moving the member to retract the heart such that the heart has freedom to undergo normal beating motion at least in the vertical direction during retraction.

    Abstract translation: 一种器官操纵器，包括至少一个吸附构件或安装在顺应性接头上的粘性盘，用于安装该抽吸构件或柔顺接头的柔性锁定臂，以及使用吸力（或粘合力）将器官缩回和悬挂在缩回位置的方法 ），使得器官在两个步骤中至少在垂直方向上自由地正常移动（例如，以打败或经历其它有限幅度运动）。 在优选实施例中，抽吸构件在手术期间施加抽吸以缩回跳动心脏并将其悬挂在缩回位置。 随着缩回的心脏跳动，柔顺关节允许其至少在垂直方向上自由地膨胀和自然地收缩（或自然地移动），使得血液动力学功能不受损害。 抽吸构件符合或可以符合器官解剖结构，并且其内表面优选地是平滑的并且衬有吸收材料，以改善牵引力而不会对器官造成伤害。 柔性接头可以将构件连接到可调节地安装到胸骨牵开器或手术台的臂上。 柔性接头可以是滑动球接头，铰接接头，在槽中滑动的销，万向接头，弹簧组件或另一柔性元件。 在优选实施例中，该方法包括以下步骤：将吸引构件固定在与心脏顶点同心的位置处的跳动心脏，并且在移动构件以使心脏收缩的同时向心脏施加吸力，使得心脏具有正常的自由 至少在缩回过程中垂直方向进行打击运动。

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