公开(公告)号：US12097087B2

公开(公告)日：2024-09-24

申请号：US18340416

申请日：2023-06-23

申请人： James R. Glidewell Dental Ceramics, Inc.

发明人： Jae Won Kim

IPC分类号： A61L24/12 ,  A61C8/00 ,  A61C13/083 ,  A61K6/58 ,  A61K6/80 ,  A61K6/802 ,  A61K6/818 ,  A61K6/824 ,  A61L27/34 ,  A61L27/42 ,  C04B41/45 ,  A61C5/73 ,  A61C13/00 ,  A61K6/50 ,  A61K6/56 ,  C08G77/58 ,  C09D183/14

CPC分类号： A61C8/0013 ,  A61C8/0012 ,  A61C8/0018 ,  A61C13/083 ,  A61K6/58 ,  A61K6/802 ,  A61K6/818 ,  A61K6/824 ,  A61L27/34 ,  A61L27/427 ,  C04B41/4535 ,  A61C5/73 ,  A61C8/005 ,  A61C8/008 ,  A61C13/0022 ,  A61K6/50 ,  A61K6/56 ,  A61L2430/12 ,  C08G77/58 ,  C09D183/14

摘要： A method for making a ceramic body comprised of a ceramic material having an inhibitory effect on bacterial growth is provided. A dental prosthesis may be made of a ceramic material that comprises a molybdenum-containing component on a portion of the prosthesis that contacts the gingival surface of a patient. In one method, a porous zirconia ceramic structure is shaped in the form of a dental prosthesis, and then infiltrated with a molybdenum-containing composition, before sintering to densify the ceramic structure.

公开(公告)号：US11684456B2

公开(公告)日：2023-06-27

申请号：US17717247

申请日：2022-04-11

申请人： James R. Glidewell Dental Ceramics, Inc.

发明人： Jae Won Kim

IPC分类号： A61K6/80 ,  A61L24/00 ,  A61C8/00 ,  A61L27/34 ,  A61C13/083 ,  A61L27/42 ,  A61K6/58 ,  A61K6/818 ,  A61K6/824 ,  A61K6/802 ,  C04B41/45 ,  C08G77/58 ,  C09D183/14 ,  A61C5/73 ,  A61C13/00 ,  A61K6/50 ,  A61K6/56

CPC分类号： A61C8/0013 ,  A61C8/0012 ,  A61C8/0018 ,  A61C13/083 ,  A61K6/58 ,  A61K6/802 ,  A61K6/818 ,  A61K6/824 ,  A61L27/34 ,  A61L27/427 ,  C04B41/4535 ,  A61C5/73 ,  A61C8/005 ,  A61C8/008 ,  A61C13/0022 ,  A61K6/50 ,  A61K6/56 ,  A61L2430/12 ,  C08G77/58 ,  C09D183/14

摘要： A method for making a ceramic body comprised of a ceramic material having an inhibitory effect on bacterial growth is provided. A dental prosthesis may be made of a ceramic material that comprises a molybdenum-containing component on a portion of the prosthesis that contacts the gingival surface of a patient. In one method, a porous zirconia ceramic structure is shaped in the form of a dental prosthesis, and then infiltrated with a molybdenum-containing composition, before sintering to densify the ceramic structure.

公开(公告)号：US20220000722A1

公开(公告)日：2022-01-06

申请号：US17463002

申请日：2021-08-31

申请人： MESOSIL INC.

发明人： Cameron Alexander STEWART ,  Benjamin David HATTON ,  Yoav FINER

IPC分类号： A61K6/84 ,  C08L33/12 ,  A01N25/08 ,  A01N43/40 ,  A01N47/44 ,  A61K6/20 ,  A61K6/35 ,  A61K6/40 ,  A61K6/54 ,  A61K6/71 ,  A61K6/74 ,  A61K6/76 ,  A61K6/80 ,  A61K6/802 ,  A61K6/849 ,  A61K6/853 ,  A61K6/86 ,  A61K6/864 ,  A61K6/871 ,  A61K9/00 ,  A61K9/14 ,  A61K9/51 ,  A61K31/155 ,  A61K31/20 ,  A61K31/444 ,  A61K31/4425 ,  A61K31/785 ,  A61L27/02 ,  A61L27/10 ,  A61L27/12 ,  A61L27/30 ,  A61L27/32 ,  A61L27/42 ,  A61L27/44 ,  A61L27/54 ,  A61L27/56 ,  A61P1/02 ,  A61P31/02 ,  A61P31/04 ,  C07C279/14 ,  C07C279/26 ,  C07D213/20 ,  C07D213/74 ,  C08K3/22 ,  C08K3/32

摘要： A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.

公开(公告)号：US10799429B2

公开(公告)日：2020-10-13

申请号：US16078069

申请日：2017-02-16

申请人： 3M INNOVATIVE PROPERTIES COMPANY

发明人： Kai U. Claussen ,  Johannes M. Leykauff ,  Christine Lienau ,  Reinhold Hecht ,  Peter Braun ,  Markus Mikulla

IPC分类号： A61K6/853 ,  A61K6/54 ,  A61K6/76 ,  A61K6/80 ,  A61K6/889 ,  A61K6/898 ,  A61C5/50 ,  A61C5/00

摘要： The invention relates to a kit of parts for preparing a glass ionomer composition for dental use, the kit comprising a Paste A and a Paste B, Paste A comprising water, acid-reactive inorganic filler A, phyllo silicate(s), Paste B comprising water, poly-acid, non acid-reactive filler B, optionally chelating agent. The invention also relates to a hardenable composition obtainable by combining the pastes of the kit or parts and to the use of such a composition as or for preparing a dental cement, dental filling material, dental core build up material or dental root channel filling material.

公开(公告)号：US11872293B2

公开(公告)日：2024-01-16

申请号：US17527839

申请日：2021-11-16

申请人： Innovative Health Technologies, LLC

发明人： Darnell Kaigler, Sr.

IPC分类号： A61K6/891 ,  A61K6/80 ,  A61K6/802 ,  A61C8/02

CPC分类号： A61K6/891 ,  A61C8/0006 ,  A61K6/80 ,  A61K6/802

摘要： Embodiments described herein are related to pellets that are placed within an extraction site that is in need of bone augmentation and preservation. The pellets are typically cylindrical in shape and comprise a material and a polymer coating. The pellets may advantageously facilitate sufficient new bone growth that jaw bone deterioration is prevented. The pellets create, arrange, and assemble an ideal growth environment for new bone growth to rapidly grow and preserve the original contours of an individual's jaw bone.

公开(公告)号：US20210022839A1

公开(公告)日：2021-01-28

申请号：US16930530

申请日：2020-07-16

申请人： Ivoclar Vivadent AG

发明人： Stephan Lenz ,  Benjamin Gebhardt ,  Theresa Sujata Maria Senti ,  Stefan Lerch

IPC分类号： A61C19/00 ,  A61K6/80 ,  B65D35/08 ,  B65D35/38

摘要： The present invention relates to a container (100) for producing a self-curing or dual-curing dental synthetic material composition (200), which container comprises a deformable wall (101), having a first synthetic material component (103-1); and a second synthetic material component (103-2) for curing the synthetic material composition (200) or starting a curing reaction.

公开(公告)号：US10716648B2

公开(公告)日：2020-07-21

申请号：US15308551

申请日：2015-04-30

申请人： University of Louisville Research Foundation, Inc.

发明人： Amirali Zandinejad ,  Wei-Shao Lin ,  Dean Morton

IPC分类号： A61C13/00 ,  A61C5/77 ,  B29C64/165 ,  A61K6/15 ,  A61K6/80 ,  A61K6/813 ,  B33Y10/00 ,  B33Y80/00 ,  B28B1/00 ,  B29C35/08 ,  B29L31/00

摘要： A method of fabricating a dental restoration is provided that includes the initial step of providing a powder of a dental material. An amount of a binder is then selectively deposited onto the powder of the dental material to produce an unfinished layer of the dental material. Multiple layers of the dental material are then produced by continually providing a powder of dental material and selectively depositing an amount of a binder until a three-dimensional unfinished model is produced. The unfinished model is then separated from an amount of unaffected powder, and is sintered to produce a three-dimensional dental restoration having a functionally-graded structure.

公开(公告)号：US10668134B2

公开(公告)日：2020-06-02

申请号：US16086993

申请日：2017-03-31

申请人： National Center for Geriatrics and Gerontology

发明人： Misako Nakashima ,  Koichiro Iohara ,  Hideto Watanabe

IPC分类号： A61K38/48 ,  A61P1/02 ,  A61K9/51 ,  A61L27/38 ,  A61L27/54 ,  A61L27/50 ,  A61K6/00 ,  A61K6/80

摘要： Provided is a dental pretreatment material for dental tissue regeneration by use of dental pulp stem cells, particularly a dental pretreatment material effectively enabling dental tissue regeneration even by use of dental pulp stem cells of middle-aged or older individuals. The dental pretreatment material is characterized by comprising a serine protease, specifically trypsin. The dental pretreatment material comprising trypsin is used as an injection into a root canal before a root canal filling material comprising dental pulp stem cells and an extracellular matrix is inserted into the root canal as an attempt to regenerate a dental pulp and a dentin. The root canal filling material includes an ALK5 inhibitor, a CCR3 antagonist, or a CCL11 neutralizing antibody.

公开(公告)号：US11844849B2

公开(公告)日：2023-12-19

申请号：US17570781

申请日：2022-01-07

申请人： 3M INNOVATIVE PROPERTIES COMPANY

发明人： Bradley D. Craig ,  Timothy D. Dunbar ,  Karsten Dede ,  Adrian S. Eckert ,  Ahmed S. Abuelyaman ,  Gregory A. Kobussen ,  Christoph H. Thalacker ,  Paul J. Homnick

IPC分类号： A61K6/80 ,  A61K6/818 ,  A61K6/16 ,  A61K6/17 ,  A61K6/71 ,  A61K6/76 ,  A61K6/78 ,  A61K6/887

CPC分类号： A61K6/818 ,  A61K6/16 ,  A61K6/17 ,  A61K6/71 ,  A61K6/76 ,  A61K6/78 ,  A61K6/887 ,  A61K6/887 ,  C08L33/08 ,  A61K6/887 ,  C08L33/10

摘要： Dental compositions and methods of formulating a dental composition are described. In one embodiment, the dental composition comprises a polymerizable resin comprising one or more ethylenically unsaturated monomers or oligomers and nanoparticles. The nanoparticles have a refractive index of at least 1.600 and an average discrete or aggregate particle size of no greater than 100 nm. The dental composition further comprises inorganic metal oxide filler having a discrete or aggregate average particle size of at least 200 nm. The nanoparticles are present at a concentration to provide a refractive index differential between the cured polymerizable resin and inorganic metal oxide filler such that the contrast ratio of the dental composition is at least 40.

公开(公告)号：US20230075693A1

公开(公告)日：2023-03-09

申请号：US17786071

申请日：2020-12-16

申请人： KURARAY NORITAKE DENTAL INC.

发明人： Tatsuya KAJIKAWA ,  Yuki SUGA

IPC分类号： A61K6/80 ,  A61K6/30

摘要： The present invention provides a dental curable composition that shows fluorescence sufficient to enable highly aesthetic harmonious restoration almost indistinguishable from surrounding natural teeth, and that, while having sufficient mechanical strength and radiopacity and good ease of polishing as a restorative material, desirably resists discoloration not only in the intraoral environment but under accelerated heating conditions and under xenon light, without losing fluorescence even under these conditions. The present invention also provides a cured product of such a dental curable composition. The present invention relates to a dental curable composition comprising a polymerizable monomer (A), an inorganic filler (B), a polymerization initiator (C), and a fluorescent agent (D), wherein the fluorescent agent (D) comprises a 9- to 11-membered benzo-fused heterocyclic compound containing two or more heteroatoms (excluding benzoimidazole compounds).