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66 条记录 (耗时 0.048 秒)

    Intermediate in Production of [2-(3,3,5,5-Tetramethylcyclohexyl)phenyl]Piperazine Compound
    3.
    发明申请
    Intermediate in Production of [2-(3,3,5,5-Tetramethylcyclohexyl)phenyl]Piperazine Compound 审中-公开
    [2-（3,3,5,5-四甲基环己基）苯基]哌嗪化合物的制备中间体

    公开(公告)号：US20090163715A1

    公开(公告)日：2009-06-25

    申请号：US11920920

    申请日：2006-05-25

    申请人： Mitsuo Nagai ,  Kazumasa Nara ,  Kazunori Wakasugi ,  Toshihiko Naito

    发明人： Mitsuo Nagai ,  Kazumasa Nara ,  Kazunori Wakasugi ,  Toshihiko Naito

    IPC分类号： C07D241/04 ,  C07C211/44 ,  C07D207/30 ,  C07D211/08 ,  C07C55/06 ,  C07C57/15 ,  C07C309/01

    CPC分类号： C07C233/05 ,  C07C211/45 ,  C07C233/25 ,  C07C275/32 ,  C07D295/033 ,  Y02P20/55

    摘要： A compound represented by the general formula below or a salt thereof is a useful intermediate in the production of a [2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine compound that has excellent cell adhesion inhibitory effect and cell invasion inhibitory effect and therefore is useful as a therapeutic or prophylactic agent for various inflammatory diseases and autoimmune diseases induced by the adhesion and invasion of leukocytes, such as inflammatory bowel diseases (particularly ulcerative colitis or Crohn's disease), irritable bowel syndrome, rheumatoid arthritis, psoriasis, multiple sclerosis, asthma and atopic dermatitis. wherein R1 and R2 independently represent hydrogen or a protecting group for an amino group, or R1 and R2 bond together to form an optionally substituted pyrrole ring.

    摘要翻译： 由以下通式表示的化合物或其盐是制备具有优异的细胞粘附抑制作用和细胞侵袭抑制作用的[2-（3,3,5,5-四甲基环己基）苯基]哌嗪化合物的有用中间体 因此可用作各种炎性疾病和由白细胞的粘附和侵入引起的自身免疫性疾病（例如炎性肠病（特别是溃疡性结肠炎或克罗恩病）），肠易激综合征，类风湿性关节炎，牛皮癣， 多发性硬化，哮喘和特应性皮炎。 其中R 1和R 2独立地表示氢或氨基的保护基，或者R 1和R 2一起形成任选取代的吡咯环。

    Method of producing near-infrared absorbing dye compound
    4.
    发明授权
    Method of producing near-infrared absorbing dye compound 有权
    生产近红外吸收染料化合物的方法

    公开(公告)号：US07473802B2

    公开(公告)日：2009-01-06

    申请号：US11514181

    申请日：2006-09-01

    申请人： Keizo Kimura ,  Tomohito Masaki ,  Osamu Uchida ,  Katsuyoshi Yamakawa

    发明人： Keizo Kimura ,  Tomohito Masaki ,  Osamu Uchida ,  Katsuyoshi Yamakawa

    IPC分类号： C07C55/06 ,  C07C249/00

    CPC分类号： C09B53/02 ,  C07C249/02 ,  G11B7/246 ,  C07C251/30

    摘要： A method of producing a near-infrared absorbing dye compound, useful for image forming materials, infrared heat-sensitive recording devices, optical film materials, and the like, containing a process of reacting a compound represented by formula (I) with peroxomonosulfuric acid or its salt. wherein R111, R112, R121, R122, R131, R132, R141 and R142 each independently represent a hydrogen atom, an aliphatic group or an aromatic group; R103, R113, R123, R133 and R143 each independently represent a substituent; and n103, n113, n123, n133 and n143 each independently denote an integer from 0 to 4.

    摘要翻译： 一种制造用于成像材料的红外吸收染料化合物的方法，红外热敏记录装置，光学膜材料等，其包含使式（I）表示的化合物与碳酸二氢酸反应的方法或 它的盐 其中R111，R112，R121，R122，R131，R132，R141和R142各自独立地表示氢原子，脂族基团或芳香族基团; R103，R113，R123，R133和R143各自独立地表示取代基; n103，n113，n123，n133和n143各自独立地表示0〜4的整数。

    Heat activated tertiary amine urethane catalysts
    5.
    发明授权
    Heat activated tertiary amine urethane catalysts 有权
    热活化叔胺氨基甲酸酯催化剂

    公开(公告)号：US07351859B2

    公开(公告)日：2008-04-01

    申请号：US10838136

    申请日：2004-05-03

    申请人： Robert A. Grigsby, Jr. ,  Robert L. Zimmerman

    发明人： Robert A. Grigsby, Jr. ,  Robert L. Zimmerman

    IPC分类号： C07C55/06

    CPC分类号： C08G18/1875 ,  C07C217/08

    摘要： This invention concerns a compound formed from a tertiary amine-carboxylic acid salt, where the carboxylic acid and tertiary amine are selected such that the catalyst salt is blocked at room temperature and becomes unblocked at an elevated temperature. The compound is useful as a heat activated urethane catalyst.

    摘要翻译： 本发明涉及由叔胺 - 羧酸盐形成的化合物，其中选择羧酸和叔胺，使得催化剂盐在室温下被阻断并在升高的温度下被阻断。 该化合物可用作热活化聚氨酯催化剂。

    Process for preparing oxalic acid and esters of same
    9.
    发明授权
    Process for preparing oxalic acid and esters of same 失效
    制备草酸及其酯的方法

    公开(公告)号：US4118589A

    公开(公告)日：1978-10-03

    申请号：US649235

    申请日：1976-01-15

    申请人： Luigi Cassar ,  Andrea Gardano

    发明人： Luigi Cassar ,  Andrea Gardano

    IPC分类号： C07C69/36 ,  B01J23/00 ,  B01J27/00 ,  B01J31/00 ,  C07B61/00 ,  C07C51/145 ,  C07C51/00 ,  C07C55/06

    CPC分类号： C07C51/145

    摘要： The present invention relates to a process for preparing oxalic acid and esters of oxalic acid. More particularly, this invention relates to a catalytic process for preparing oxalic acid and esters of same by the oxidative reaction, in a liquid phase, of carbon monoxide and water or alcohols with oxygen in the presence of redox systems.The catalyst systems used in accordance with this invention comprises a redox catalyst consisting essentially of a salt of Pd (II) and salts of a metal more electropositive than Pd having at least two oxidation states and, optionally, salts of alkaline metals, and co-catalytic amounts of at least one base having the formula R.sub.3 N in which the groups R which may be like or unlike and are selected from the group consisting of hydrogen and alkyl radicals having from 1 to 10 carbon atoms.

    摘要翻译： 本发明涉及草酸和草酸酯的制备方法。 更具体地说，本发明涉及在氧化还原体系存在下，通过一氧化碳和水或醇与氧的氧化反应在液相中制备草酸及其酯的催化方法。

    Process for the production of oxalic acid
    10.
    发明授权
    Process for the production of oxalic acid 失效
    草酸生产工艺

    公开(公告)号：US3864393A

    公开(公告)日：1975-02-04

    申请号：US43137374

    申请日：1974-01-07

    申请人： HUELS CHEMISCHE WERKE AG

    发明人： ROHL HERMANN ,  KNEPPER WILHELM

    IPC分类号： C07C55/06 ,  C07C51/00 ,  C07C51/31 ,  C07C67/00 ,  C07C51/24

    CPC分类号： C07C51/313 ,  C07C55/06

    摘要： The nitrous oxides released when ethylene oxide is introduced at 30*-70*C. into aqueous nitric acid of 50-70 percent by weight of HNO3 is recirculated thereto and gaseous oxygen is introduced into the nitric acid. A post-oxidation holding of the oxidation mixture for 8-24 hours at 30*-70*C. increases the yield of oxalic acid.

    摘要翻译： 当环氧乙烷在30-70℃下引入含有50-70％（重量）HNO 3的硝酸水溶液中时释放的氧化亚氮被再循环，气态氧被引入硝酸。 氧化混合物在30-70℃下后氧化保持8-24小时，提高了草酸的产率。