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30 条记录 (耗时 0.012 秒)

    Cyclohexylamines
    2.
    发明授权
    Cyclohexylamines 失效
    环己胺

    公开(公告)号：US3994975A

    公开(公告)日：1976-11-30

    申请号：US512423

    申请日：1974-10-07

    申请人： Bernardus A. Oude Alink ,  Neil E. S. Thompson

    发明人： Bernardus A. Oude Alink ,  Neil E. S. Thompson

    IPC分类号： C10L1/222 ,  C07C85/08 ,  C07C87/36 ,  C07C87/45

    CPC分类号： C10L1/2222 ,  C10L1/2225

    摘要： This invention relates to the reductive amination of unsaturated cyclic ketones; to cyclic amines prepared thereby; and to uses thereof. For example, when isophorone is reductively aminated, trimethyl cyclohexylamines and cyclohexenamines are obtained. This invention also relates to uses thereof, for example, as fuel additives, particularly for stabilizing distillate fuels.

    摘要翻译： 本发明涉及不饱和环酮的还原胺化; 由此制备的环胺; 并使用它们。 例如，当异佛尔酮被还原胺化时，得到三甲基环己胺和环己烯胺。 本发明还涉及其用途，例如作为燃料添加剂，特别是用于稳定馏出燃料。

    Fluorinated tertiary amino ethers
    4.
    发明授权
    Fluorinated tertiary amino ethers 失效
    氟化泰坦尼治亚

    公开(公告)号：US3882178A

    公开(公告)日：1975-05-06

    申请号：US38686173

    申请日：1973-08-09

    申请人： HOECHST AG

    发明人： BENNINGER SIEGFRIED ,  REBSDAT SIEGFRIED ,  KOHLHAAS RUDOLF

    IPC分类号： A61K9/08 ,  C07B61/00 ,  C07C217/26 ,  C23C2/02 ,  C25B3/08 ,  G21C15/28 ,  H01B3/24 ,  C07C87/36

    CPC分类号： C25B3/08 ,  C23C2/02

    摘要： Tetrafluoro-ethylene can be added to monoamines having oxyethyl or oxypropyl groups in aprotic polar solvents in the presence of alkali metals. The new monoamines obtained having the radicals tetrafluoro-ethyloxy-ethyl or tetrafluoro-ethyl-oxy-propyl are electrolyzed in anhydrous hydrofluoric acid, thus forming new monoamines in which all or nearly all hydrogen atoms of the starting compounds are replaced by fluorine.

    摘要翻译： 在碱金属存在下，四氟乙烯可以加入非质子极性溶剂中具有氧乙基或氧丙基的单胺。 获得的具有四氟乙氧基 - 乙基或四氟 - 乙基 - 氧基 - 丙基基团的新单胺在无水氢氟酸中电解，从而形成新的单胺，其中起始化合物的全部或几乎全部氢原子被氟取代。

    Pseudo-aminosugars, their production and use
    6.
    发明授权
    Pseudo-aminosugars, their production and use 失效
    伪氨基糖，其生产和使用

    公开(公告)号：US4827036A

    公开(公告)日：1989-05-02

    申请号：US367105

    申请日：1982-04-09

    申请人： Yukihiko Kameda ,  Satoshi Horii

    发明人： Yukihiko Kameda ,  Satoshi Horii

    IPC分类号： C12P13/00 ,  C07C87/36

    CPC分类号： C12P13/001 ,  C12R1/55 ,  Y10S435/898

    摘要： Novel pseudo-aminosugars, or 5-amino-1-hydroxymethyl-1,2,3,4-cyclohexanetetrol, their production and use.These pseudo-aminosugars exhibit excellent .alpha.-glucosidase inhibitory activity and are useful for hyperglycemic symptoms and various disorders caused by hyperglycemia.

    摘要翻译： 新型假氨基糖或5-氨基-1-羟甲基-1,2,3,4-环己烷酮，其生产和使用。 这些假氨基糖显示出优异的α-葡糖苷酶抑制活性，并且可用于高血糖症状和由高血糖引起的各种疾病。

    Preparation of trans cyclohexane 1,4-diamine
    7.
    发明授权
    Preparation of trans cyclohexane 1,4-diamine 失效
    反式环己烷1,4-二胺的制备

    公开(公告)号：US4486603A

    公开(公告)日：1984-12-04

    申请号：US420186

    申请日：1982-09-20

    申请人： Hans Zengel ,  Manfred Bergfeld

    发明人： Hans Zengel ,  Manfred Bergfeld

    IPC分类号： C07C271/24 ,  C07C67/00 ,  C07C209/00 ,  C07C209/56 ,  C07C211/36 ,  C07C231/00 ,  C07C231/02 ,  C07C235/58 ,  C07C239/00 ,  C07C241/00 ,  C07C263/06 ,  C07C265/00 ,  C07C265/14 ,  C07C273/18 ,  C07C275/04 ,  C07C275/26 ,  C07C311/56 ,  C07D295/20 ,  C07C85/00 ,  C07C87/36

    CPC分类号： C07C273/1845 ,  C07C311/56

    摘要： A process is disclosed for selectively making trans-cyclohexane-1,4-diisocyanate, trans-cyclohexane-1,4-diamine, a trans-cyclohexane-1,4-diurethane, a trans-cyclohexane-1,4-diurea and trans-cyclohexane-1,4-disulphonyl urea by reacting ammonia with a mixture of cis and trans cyclohexane-1,4-dicarboxylic acid, a lower alkyl ester, a glycol ester, an oligomeric ester or a polyester to make a solid trans-dicarboxylic acid diamide in a first step. The diamide is chlorinated to form trans-cyclohexane-1,4-dicarboxylic acid-bis-N-chloramide. The latter compound is then converted into a(a) trans-cyclohexane-1,4-diamine with an alkali metal hydroxide or alkaline earth metal hydroxide; or into a(b) a trans-cyclohexane-1,4-diurethane by reaction with an alcohol or glycol in a reaction mixture containing an alkali metal hydroxide or alkaline earth metal hydroxide; or into(c) a trans-cyclohexane-1,4-diurea by reaction with a primary or secondary amine in a reaction mixture containing an alkali metal hydroxide or alkaline earth metal hydroxide; or into a(d) trans-cyclohexane-1,4-sulphonyl urea by reaction with a primary sulphonamide in a reaction mixture containing an alkali metal hydroxide and dimethyl formamide and water.The diurea prepared in (c) may be converted into trans-cyclohexane-1,4-diisocyanate with gaseous hydrogen chloride in an inert solvent. The diurethane prepared in (b) and the disulphonyl urea prepared in (d) may be thermally decomposed into trans-cyclohexane-1,4-diisocyanate.

    摘要翻译： 公开了一种选择性制备反式环己烷-1,4-二异氰酸酯，反式环己烷-1,4-二胺，反式环己烷-1,4-二氨基甲酸酯，反式环己烷-1,4-二脲和反式环己烷-1,4-二脲 - 环己烷-1,4-二磺酰脲通过使氨与顺式和反式环己烷-1,4-二羧酸，低级烷基酯，乙二醇酯，低聚酯或聚酯的混合物反应制得固体反式二羧酸 酸二酰胺在第一步。 将二酰胺氯化以形成反式 - 环己烷-1,4-二羧酸 - 双-N-氯酰胺。 然后将后一种化合物用碱金属氢氧化物或碱土金属氢氧化物转化为（a）反式 - 环己烷-1,4-二胺; 或者通过与含有碱金属氢氧化物或碱土金属氢氧化物的反应混合物中的醇或二醇反应形成（b）反式环己烷-1,4-二氨基甲酸酯; 或者通过与含有碱金属氢氧化物或碱土金属氢氧化物的反应混合物中的伯胺或仲胺反应形成（c）反式环己烷-1,4-二脲; 或通过与含有碱金属氢氧化物和二甲基甲酰胺和水的反应混合物中的伯磺酰胺反应而形成（d）反式 - 环己烷-1,4-磺酰脲。 （c）中制备的二脲可以在惰性溶剂中用气态氯化氢转化成反式 - 环己烷-1,4-二异氰酸酯。 （b）中制备的二氨基甲酸酯和（d）中制备的二磺酰脲可以热分解成反式环己烷-1,4-二异氰酸酯。

    Naphthacene derivatives
    9.
    发明授权
    Naphthacene derivatives 失效
    萘衍生物

    公开(公告)号：US3665018A

    公开(公告)日：1972-05-23

    申请号：US3665018D

    申请日：1969-07-14

    申请人： RHONE POULENC SA

    发明人： JOLLES GEORGES

    IPC分类号： C07H15/252 ,  C07C87/10 ,  C07C87/36

    CPC分类号： C07H15/252 ,  Y10S514/908

    摘要： New derivatives of 4-methoxy-5,12-dioxo-6,9,11-trihydroxy-9acetyl-5,7,8,9,10,12 -hexahydronaphthacene with a substituent -OCO-R in the 7-position, wherein R represents cyclohexyl substituted by an aminomethyl group, or by at least one amino group, monoalkylamino group of which the alkyl radical contains one to five carbon atoms, dialkylamino group of which each alkyl radical contains one to five carbon atoms, or sulphomethylamino group, or R represents a said substituted-cyclohexyl group also substituted by at least one hydroxy group or alkanoyloxy group of which the alkanoyl radical contains one to five carbon atoms, or R represents a phenylalkyl group of which the alkyl radical contains one to four carbon atoms and is substituted by a bis(2chlorethyl)amino group, or a piperidyl group, and non-toxic salts thereof, have useful properties against leukaemia L1210 in mice, combined with a low toxicity.