利索-全球专利检索

  1. Login
  2. Sign Up

Search Results

63 records (took 0.015 seconds)

    Process for preparing substituted and unsubstituted arylalkylamines
    4.
    发明授权
    Process for preparing substituted and unsubstituted arylalkylamines 失效
    制备取代和未取代的芳基烷基胺的方法

    公开(公告)号：US5430189A

    公开(公告)日：1995-07-04

    申请号：US185098

    申请日：1994-01-19

    Applicant: Joseph A. McDonough ,  Ahmed M. Tafesh ,  Olan S. Fruchey

    Inventor： Joseph A. McDonough ,  Ahmed M. Tafesh ,  Olan S. Fruchey

    IPC: C07C209/00 ,  C07C209/40 ,  C07C215/52 ,  C07C249/08 ,  C07C209/38

    CPC classification number: C07C215/52 ,  C07C209/00 ,  C07C209/40 ,  C07C249/08

    Abstract: An arylisonitrosoalkanone is hydrogenated in the presence of a noble metal catalyst and a weak carboxylic acid to form an arylalkanolamine which is then hydrogenated in the presence of a strong mineral acid and the transition metal catalyst to form an arylalkylamine. When the arylisonitrosoalkanone is an isonitrosoacetophenone, the isonitrosoacetophenone is prepared by one of two methods.In the first method, a substituted or an unsubstituted isonitrosoacetophenone is prepared from a corresponding substituted or unsubstituted acetophenone by oxidizing the acetophenone to form a substituted or an unsubstituted phenylglyoxalacetal in a reactor, hydrolyzing the phenylglyoxal acetal in the same reactor to form a corresponding substituted or unsubstituted phenylglyoxal, and condensing the phenylglyoxal with hydroxylamine or a salt thereof in the same reactor to form the substituted or unsubstituted isonitrosoacetophenone. Alternatively, the substituted or unsubstituted isonitrosoacetophenone is prepared from the corresponding substituted or unsubstituted acetophenone by reacting the substituted or unsubstituted acetophenone in water with a source of a nitrosonium ion in the presence of a strong acid to form a corresponding substituted or unsubstituted phenylglyoxal, and condensing the phenylglyoxal with hydroxylamine or a salt thereof to form the substituted or unsubstituted isonitrosoacetophenone. In either method, any strong acid that might be present in the reaction mass following the condensation to the isonitrosoacetophenone shall be removed therefrom prior to initiating the hydrogenation of the isonitrosoacetophenone to the arylalkanolamine.

    Abstract translation: 芳基亚硝基烷酮在贵金属催化剂和弱羧酸的存在下氢化形成芳基烷醇胺，然后在强无机酸和过渡金属催化剂的存在下氢化形成芳基烷基胺。 当芳基亚硝基烷酮是异硝基苯乙酮时，通过两种方法之一制备异硝基苯乙酮。 在第一种方法中，通过在反应器中氧化苯乙酮以形成取代或未取代的苯基乙醛缩醛，由相应的取代或未取代的苯乙酮制备取代或未取代的异硝基苯乙酮，在相同的反应器中水解苯乙醛缩醛形成相应的取代或未取代的苯乙酮缩醛， 未取代的苯基乙二醛，并将苯乙醛酸与羟胺或其盐在同一反应器中缩合形成取代或未取代的异硝基苯乙酮。 或者，取代或未取代的异硝基苯乙酮由相应的取代或未取代的苯乙酮通过在强酸存在下使取代或未取代的苯乙酮在水中与亚硝鎓离子源反应形成相应的取代或未取代的苯基乙二醛，并将 苯基乙二醛与羟胺或其盐形成取代或未取代的异硝基苯乙酮。 在任一种方法中，在将异亚氨基苯乙酮氢化成芳基烷醇胺之前，任何在与异亚硝基苯乙酮缩合后可能存在于反应物质中的强酸应从其中除去。

    Process for the preparation of aromatic amines
    8.
    发明授权
    Process for the preparation of aromatic amines 失效
    芳香胺的制备方法

    公开(公告)号：US4375561A

    公开(公告)日：1983-03-01

    申请号：US318117

    申请日：1981-11-04

    Applicant: Rudiger Berthold ,  Werner H. Muller

    Inventor： Rudiger Berthold ,  Werner H. Muller

    IPC: C07B61/00 ,  B01J23/00 ,  C07C67/00 ,  C07C209/00 ,  C07C209/40 ,  C07C209/68 ,  C07C211/45 ,  C07C211/55 ,  C07C85/11

    CPC classification number: C07C209/68

    Abstract: Aromatic amines are obtained from the corresponding cycloaliphatic oximes by heating the oxime to a temperature of from 150.degree. to 350.degree. C. in an ether group containing solvent in the presence of a catalyst containing a noble metal of the 8th auxiliary group of the Periodic Table of Elements. The solvent is preferably an aliphatic ether, especially a lower dialkyl ether of a polyethyleneglycol.

    Abstract translation: 在含有第8族元素周期表的贵金属的催化剂存在下，通过将肟在含有醚基的溶剂中加热至150℃至350℃的温度，从相应的脂环族肟得到芳族胺 的元素。 溶剂优选为脂族醚，特别是聚乙二醇的低级二烷基醚。

    Process for preparing ortho substituted phenylamines
    10.
    发明授权
    Process for preparing ortho substituted phenylamines 失效
    邻位取代苯胺的制备方法

    公开(公告)号：US06953866B2

    公开(公告)日：2005-10-11

    申请号：US10769365

    申请日：2004-01-30

    Applicant: Russell E. Malz, Jr. ,  Ranjit Kumar ,  Luis Javier Garces ,  Steven L. Suib

    Inventor： Russell E. Malz, Jr. ,  Ranjit Kumar ,  Luis Javier Garces ,  Steven L. Suib

    IPC: C07C209/02 ,  C07C209/40 ,  C07C213/00 ,  C07C209/18

    CPC classification number: C07C209/02 ,  C07C209/40 ,  C07C213/00

    Abstract: A process is disclosed for preparing ortho substituted phenylamines comprising contacting phenylhydroxylamine, optionally substituted with at least one inert substituent, with a nucleophilic reagent in the presence of a manganese oxide at a temperature between about 10° C. and about 170° C. and a pressure from subatmospheric to superatmospheric such that an ortho substituted phenylamine, optionally correspondingly substituted with at least one inert substituent, is predominantly formed.

    Abstract translation: 公开了用于制备邻位取代的苯基胺的方法，包括在约10℃至约170℃的温度下，在氧化锰存在下，将任选被至少一个惰性取代基取代的苯基羟胺与亲核试剂接触， 压力从低于大气压到高于大气压，使得主要形成任选相应地被至少一个惰性取代基取代的邻位取代的苯胺。

Patent Agency Ranking